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The map label for this gene is aidB [H]

Identifier: 45656282

GI number: 45656282

Start: 431902

End: 433599

Strand: Reverse

Name: aidB [H]

Synonym: LIC10382

Alternate gene names: 45656282

Gene position: 433599-431902 (Counterclockwise)

Preceding gene: 45656283

Following gene: 45656281

Centisome position: 10.14

GC content: 38.34

Gene sequence:

>1698_bases
ATGCAATACCCATTCAATCAATCTACAAATCCAGGGCTGGCTCCTTTTGATATTTCGAACTATAAAGGCAATCGAGGAAA
AAACTTTTACGAAGAAGACAGAGTATTACAGACACTTGTAGAAAAATATTCTAAAGGTTACGATTCTACACATAAGAAAG
CTATGATCGAACATCTTTTAGGTTATGGCGCCTTGGTCGGAGGAATTTTAGACGAACTTACAGAAGCTTCTCATAAAGAA
GGAAAATACGGCGAGATTGTTAAATACGACCGAACCGGAAATCGAATCGACGCAGTTGTATATTCTAATGAACAAAAACT
TTCTAGAAAAATTTCATACGACTATGGAATCGTAAATCTAAACTATCATTCATCTTGGAAACATCCTTTTACCGATTTAC
ACCGCTATGCTCTTGCTTATCTCGCCAATCAAAATGGAGAAGGTGGAGTCACTTGTCCACTTGCAATGACCGAAGGTATG
ATTAAAGTTTTAGAGGCTCTCGGAACTTCAGAACAAAAAGAAAAATATCTTCCTCTTGTTGCAGGCGAAGGAAGTCAATC
CCACTTTATGGCGGGACAATACGTAACCGAAAGAGTCGGGGGTTCTAACGTAAGCGCTAACAGAACGATCGCAAGAAAAC
AGGATAACGGTAAATGGATTCTCACGGGAGAGAAATGGTTCTGTTCTAATCCGGGAGATCTTTGGGTAACAACAGCAAGA
GTAGAAGATACAAACACAATTGGAATGTTTTTAGTTCCTAGAATTAAAGACGATGGTACTTTAAACGGACATCATATTTT
ACGTAAAAAAGATATTATCGGTTCCAGAGGTAAACTCACTGTAGAAATAGTTTATGACGGAGTAGAAGCGGAAGCACTCG
GAAGACCCGCACACGGAATCGCCAATTTAATCAAATACGTGATCGGGATTTCAAGATTACACGTATCCATCGCGGCTTCC
GGAATTTCGAGAAGAGCCTGGATGGAAGCCTACGAATACGCCAAATTTAGAACCGCTTATGGAAGTAAAATATTAGAATT
TTCTTCTTTACTAAAACAACTCAGTGATCAAAGACTCAAACACACTGCGATGTTAACTTCCATTTTCAGACATTTTCATA
CCCCTGAAACTTTAAAACTCGCAGGAGAGGTACTTGCTCCACTTTTAAAGTACAAATGTTCCGCCACCTCCACGGAAATT
ACCTATAACTCCATTTTAGTTTTAGGCGGAAACGGTATCGTAGGTGATTTTTCCCCACTTCCTAGACTACATAACGATTC
CATAATCAATGAAACTTGGGAAGGAACCCATTTATTATTAAGCGAACATGTACTTCGGGGATTTAAAAGAGAAAAAGTTG
CAAAAGCATTTTTTAAATATGTGGAAGAAATTACAGATCCAAACTCAGTAGCAGCAGAAACGACCCTTAAAAAATCAGAA
CTTTTACAAAATCTACTGGATCATTCAAGTTCTCAAGAATTGGATCTAAATCGGATTTATATCGCAGACCTGGCGTTTGA
AACATTCGCACTCGCCGCACTTTCGGACGCTTCTGGAAAAAATTCTCCAGATTCTCAAAAGGATCTGTCGGCCTTCCGAG
ACGGTTATTTAGATTTAGTAAATTCCTCTCAAACTTTTTCTCAAAAAGAAAATTTTTCTGGAAATACGGAAAATCTCAAA
TCCGTTATTCATTTCTAA

Upstream 100 bases:

>100_bases
TTATGAGTTCATGATTCTATTATTTGAGTTTCCACACTTTTAGATTTTGAAATAGACTTTAAAAATCAAATGATTCACTT
GAATCAATTAGGAAAGAACA

Downstream 100 bases:

>100_bases
ATAGAATTTTAGATTTTTATCATGTAATTAACGTGAGTTAGAAAAATATTTAGGACGCGTTAGAAAGGCAGATCATGACA
TTTGATAAACAAATTCAGAA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MQYPFNQSTNPGLAPFDISNYKGNRGKNFYEEDRVLQTLVEKYSKGYDSTHKKAMIEHLLGYGALVGGILDELTEASHKE
GKYGEIVKYDRTGNRIDAVVYSNEQKLSRKISYDYGIVNLNYHSSWKHPFTDLHRYALAYLANQNGEGGVTCPLAMTEGM
IKVLEALGTSEQKEKYLPLVAGEGSQSHFMAGQYVTERVGGSNVSANRTIARKQDNGKWILTGEKWFCSNPGDLWVTTAR
VEDTNTIGMFLVPRIKDDGTLNGHHILRKKDIIGSRGKLTVEIVYDGVEAEALGRPAHGIANLIKYVIGISRLHVSIAAS
GISRRAWMEAYEYAKFRTAYGSKILEFSSLLKQLSDQRLKHTAMLTSIFRHFHTPETLKLAGEVLAPLLKYKCSATSTEI
TYNSILVLGGNGIVGDFSPLPRLHNDSIINETWEGTHLLLSEHVLRGFKREKVAKAFFKYVEEITDPNSVAAETTLKKSE
LLQNLLDHSSSQELDLNRIYIADLAFETFALAALSDASGKNSPDSQKDLSAFRDGYLDLVNSSQTFSQKENFSGNTENLK
SVIHF

Sequences:

>Translated_565_residues
MQYPFNQSTNPGLAPFDISNYKGNRGKNFYEEDRVLQTLVEKYSKGYDSTHKKAMIEHLLGYGALVGGILDELTEASHKE
GKYGEIVKYDRTGNRIDAVVYSNEQKLSRKISYDYGIVNLNYHSSWKHPFTDLHRYALAYLANQNGEGGVTCPLAMTEGM
IKVLEALGTSEQKEKYLPLVAGEGSQSHFMAGQYVTERVGGSNVSANRTIARKQDNGKWILTGEKWFCSNPGDLWVTTAR
VEDTNTIGMFLVPRIKDDGTLNGHHILRKKDIIGSRGKLTVEIVYDGVEAEALGRPAHGIANLIKYVIGISRLHVSIAAS
GISRRAWMEAYEYAKFRTAYGSKILEFSSLLKQLSDQRLKHTAMLTSIFRHFHTPETLKLAGEVLAPLLKYKCSATSTEI
TYNSILVLGGNGIVGDFSPLPRLHNDSIINETWEGTHLLLSEHVLRGFKREKVAKAFFKYVEEITDPNSVAAETTLKKSE
LLQNLLDHSSSQELDLNRIYIADLAFETFALAALSDASGKNSPDSQKDLSAFRDGYLDLVNSSQTFSQKENFSGNTENLK
SVIHF
>Mature_565_residues
MQYPFNQSTNPGLAPFDISNYKGNRGKNFYEEDRVLQTLVEKYSKGYDSTHKKAMIEHLLGYGALVGGILDELTEASHKE
GKYGEIVKYDRTGNRIDAVVYSNEQKLSRKISYDYGIVNLNYHSSWKHPFTDLHRYALAYLANQNGEGGVTCPLAMTEGM
IKVLEALGTSEQKEKYLPLVAGEGSQSHFMAGQYVTERVGGSNVSANRTIARKQDNGKWILTGEKWFCSNPGDLWVTTAR
VEDTNTIGMFLVPRIKDDGTLNGHHILRKKDIIGSRGKLTVEIVYDGVEAEALGRPAHGIANLIKYVIGISRLHVSIAAS
GISRRAWMEAYEYAKFRTAYGSKILEFSSLLKQLSDQRLKHTAMLTSIFRHFHTPETLKLAGEVLAPLLKYKCSATSTEI
TYNSILVLGGNGIVGDFSPLPRLHNDSIINETWEGTHLLLSEHVLRGFKREKVAKAFFKYVEEITDPNSVAAETTLKKSE
LLQNLLDHSSSQELDLNRIYIADLAFETFALAALSDASGKNSPDSQKDLSAFRDGYLDLVNSSQTFSQKENFSGNTENLK
SVIHF

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=297, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI226958412, Length=280, Percent_Identity=25.3571428571429, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI226958414, Length=280, Percent_Identity=25.3571428571429, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI4503943, Length=284, Percent_Identity=28.169014084507, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082384, Length=438, Percent_Identity=24.4292237442922, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI86563383, Length=414, Percent_Identity=28.5024154589372, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI86563381, Length=438, Percent_Identity=27.8538812785388, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17538396, Length=293, Percent_Identity=27.9863481228669, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=278, Percent_Identity=24.8201438848921, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508101, Length=279, Percent_Identity=25.089605734767, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=314, Percent_Identity=25.4777070063694, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17569725, Length=303, Percent_Identity=24.7524752475248, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21355753, Length=280, Percent_Identity=26.0714285714286, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356377, Length=304, Percent_Identity=25, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24646207, Length=356, Percent_Identity=22.1910112359551, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 63034; Mature: 63034

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYPFNQSTNPGLAPFDISNYKGNRGKNFYEEDRVLQTLVEKYSKGYDSTHKKAMIEHLL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GYGALVGGILDELTEASHKEGKYGEIVKYDRTGNRIDAVVYSNEQKLSRKISYDYGIVNL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEEECCHHHHHHHHCCCEEEEEE
NYHSSWKHPFTDLHRYALAYLANQNGEGGVTCPLAMTEGMIKVLEALGTSEQKEKYLPLV
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCCCEE
AGEGSQSHFMAGQYVTERVGGSNVSANRTIARKQDNGKWILTGEKWFCSNPGDLWVTTAR
ECCCCCCCEEHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEECCEEEECCCCCEEEEEEE
VEDTNTIGMFLVPRIKDDGTLNGHHILRKKDIIGSRGKLTVEIVYDGVEAEALGRPAHGI
ECCCCCEEEEEEEEECCCCCCCCCEEEEHHHCCCCCCCEEEEEEECCCCHHHCCCCHHHH
ANLIKYVIGISRLHVSIAASGISRRAWMEAYEYAKFRTAYGSKILEFSSLLKQLSDQRLK
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTAMLTSIFRHFHTPETLKLAGEVLAPLLKYKCSATSTEITYNSILVLGGNGIVGDFSPL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCC
PRLHNDSIINETWEGTHLLLSEHVLRGFKREKVAKAFFKYVEEITDPNSVAAETTLKKSE
CCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LLQNLLDHSSSQELDLNRIYIADLAFETFALAALSDASGKNSPDSQKDLSAFRDGYLDLV
HHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
NSSQTFSQKENFSGNTENLKSVIHF
CCCHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MQYPFNQSTNPGLAPFDISNYKGNRGKNFYEEDRVLQTLVEKYSKGYDSTHKKAMIEHLL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GYGALVGGILDELTEASHKEGKYGEIVKYDRTGNRIDAVVYSNEQKLSRKISYDYGIVNL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEEECCHHHHHHHHCCCEEEEEE
NYHSSWKHPFTDLHRYALAYLANQNGEGGVTCPLAMTEGMIKVLEALGTSEQKEKYLPLV
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCCCEE
AGEGSQSHFMAGQYVTERVGGSNVSANRTIARKQDNGKWILTGEKWFCSNPGDLWVTTAR
ECCCCCCCEEHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEECCEEEECCCCCEEEEEEE
VEDTNTIGMFLVPRIKDDGTLNGHHILRKKDIIGSRGKLTVEIVYDGVEAEALGRPAHGI
ECCCCCEEEEEEEEECCCCCCCCCEEEEHHHCCCCCCCEEEEEEECCCCHHHCCCCHHHH
ANLIKYVIGISRLHVSIAASGISRRAWMEAYEYAKFRTAYGSKILEFSSLLKQLSDQRLK
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTAMLTSIFRHFHTPETLKLAGEVLAPLLKYKCSATSTEITYNSILVLGGNGIVGDFSPL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCC
PRLHNDSIINETWEGTHLLLSEHVLRGFKREKVAKAFFKYVEEITDPNSVAAETTLKKSE
CCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LLQNLLDHSSSQELDLNRIYIADLAFETFALAALSDASGKNSPDSQKDLSAFRDGYLDLV
HHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
NSSQTFSQKENFSGNTENLKSVIHF
CCCHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]