| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is cya [H]
Identifier: 45656150
GI number: 45656150
Start: 280557
End: 282458
Strand: Reverse
Name: cya [H]
Synonym: LIC10245
Alternate gene names: 45656150
Gene position: 282458-280557 (Counterclockwise)
Preceding gene: 45656151
Following gene: 45656148
Centisome position: 6.6
GC content: 35.59
Gene sequence:
>1902_bases ATGCCCGTTCCTAAAGCCTGGACTAGAATCCAAGAGCCAAACGGAAAAAATTATCCAGGAACCGGAATTGCAACATATTT TTTGAAAGTAATTCTACCAGAAAACCTAAGTTCAAACAATCTTGCAATCTTAGCCGAAACTTCGGAAACAGCATACGAGG TTTGGATAGACGATAACAAAATCGGAGCCCAAGGTGTTCCTGGAGAAACAGCAGATACCTCTACTCCAGAATGGAACGTA AAAATTTTACCGTTTCAAATTAATAAGAAAGAATTTCAAATTAGAATTCCACTTTCCAATTTTTATCATGCGAGAGGAGG CTTGACCGCGCGTCTGATTTTAGGTAACGAAGATCAGATCATTCGACTACGGGAAAGAAGAATGACCATGGATGTATTTC TTCTCGGATTTTTAGTCGCGATGGCGTTATATCATTTTACTCTTTATTTTTTGAGAAAAAAAGACGCAGCACTTTGGTAT TTTGGAACTATTTGTTTTGTATTTTGTTTTAGAGAAATTAGTACCGGACAAAATCTGATTCAAGTAATTGTTCCTGGTAT TTCGTATAACGTTCATATGCGAATTGTATATTTAAGTTTTTATCTTCTTACGCCGATTACCGCCGCATTTTTACGCGCCT TATTTCCAGAAGAACTAAAAAAAGAAATCTACTATGGAATCGTTTTTATCTCCTCTATCTTTTCTTTGATAGTCATTTCT CAAGATCCCGTTCTGTTTACCGCAACTATAGAGTTATATTATTTATTTACATTTTTTTGTTTTGCGATTGGATTTTACGT ATTAATGCTCGCGTTGATCCGAAAAAAGCCAGGAGCAATAGCCATATTAGTCGGAATGTTAGGGATCTTTCTTTCATACA GTCAGGATATTTTTTACACAAAAAGAATCATACCTACGTTTATACTTGCCCCATTTGGATTGATTGCTCTCATTTTTTCC GAAGCATATCTTTTAGCTAAAAGGTATTCACTTGCTTTTAACGCAGTAGAAGACATGTCCGAAAGTTTAAAAAAAATTAA TTCTTCTTATAGGCTTTTTGTCCCTAAAGAATTATTAAAAATATTAAATAAACATGATATTCTTGACATTAAACTCGGAG ATATAGCGGAAGAAGAAATGAGTCTTCTCTATAACGAAATTCGAACCTTTTCTGATTTTTCGGAAAAAATAACCGGAAAA GAAAATTTTGAATTTATTAATTCTTTTTTAGGTAAGGTCGGTCCTGCAATTCGAGAAAGGGACGGGTTTATCGATAAATA TTTTGGAGAAGCGTTTTTGGCCTTATTTCCCCCGGAGCCGGAAAAGGCTTTAGAAAGCGCCATTGAAATACAACGAATTT TAAGAGAATTCAATCGAGAAAGAATCGCAAACGGAAAAGACCCCATCCGTTCCGGAAGTGGGATTCATACAGGACCGATC TTACTTGGAACGATTGGAGAAACGGAAAGAATGGAAAGTACGGTGATCTCTTCTTCGGTAAACGTGGCTTCTAAAATTGT ACAACTCTCTAGAACATACGAATCTTCACTATTGATCACCGATTCTACTCTATTTCGCTTAACAAATTCGTCCGAATACT TTTACAGAGTTGTGGATCGGATTCAAATTCGGGATCAAAGAAGTATTTACACCGTTTTAGAAGTTCTCAACGGACTTCCT GAAAACTTAATCGATTCTTACATGAAAACAAGAGAAGAATTTGAACACGGAATTCTTTTATTTCGAGAAAAACATTTTGA GGAAGCATGTCTTATTTTTAATCGTATCTTGGAAAAGAATCGAGTCGATCAAGCCGCAAGAGTCTACTTAGAAAAATCAG TTCACAATTGCAGATTTGGAGTTCCTGAAAATTGGCAAGGAATCACTCTTTTAGAAGACTAG
Upstream 100 bases:
>100_bases TTTTGAACAACACGGTCCGGTAGCTTTACAAGGAGATTGGATCTTTCGTTGGAAAGAATTTATTAAAAATCCTAAAATCG ATTCTGAAAAAAACCGAATC
Downstream 100 bases:
>100_bases TTTACAGTAATAATCTAAACTTGAGTGTAAGTTTTTAAATCCAACTTAAAACTGTACAATAGAGTTGTTGAAAAATTTCC CTAGTTCCAATTAACAAAAC
Product: adenylate/guanylate cyclase
Products: NA
Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase [H]
Number of amino acids: Translated: 633; Mature: 632
Protein sequence:
>633_residues MPVPKAWTRIQEPNGKNYPGTGIATYFLKVILPENLSSNNLAILAETSETAYEVWIDDNKIGAQGVPGETADTSTPEWNV KILPFQINKKEFQIRIPLSNFYHARGGLTARLILGNEDQIIRLRERRMTMDVFLLGFLVAMALYHFTLYFLRKKDAALWY FGTICFVFCFREISTGQNLIQVIVPGISYNVHMRIVYLSFYLLTPITAAFLRALFPEELKKEIYYGIVFISSIFSLIVIS QDPVLFTATIELYYLFTFFCFAIGFYVLMLALIRKKPGAIAILVGMLGIFLSYSQDIFYTKRIIPTFILAPFGLIALIFS EAYLLAKRYSLAFNAVEDMSESLKKINSSYRLFVPKELLKILNKHDILDIKLGDIAEEEMSLLYNEIRTFSDFSEKITGK ENFEFINSFLGKVGPAIRERDGFIDKYFGEAFLALFPPEPEKALESAIEIQRILREFNRERIANGKDPIRSGSGIHTGPI LLGTIGETERMESTVISSSVNVASKIVQLSRTYESSLLITDSTLFRLTNSSEYFYRVVDRIQIRDQRSIYTVLEVLNGLP ENLIDSYMKTREEFEHGILLFREKHFEEACLIFNRILEKNRVDQAARVYLEKSVHNCRFGVPENWQGITLLED
Sequences:
>Translated_633_residues MPVPKAWTRIQEPNGKNYPGTGIATYFLKVILPENLSSNNLAILAETSETAYEVWIDDNKIGAQGVPGETADTSTPEWNV KILPFQINKKEFQIRIPLSNFYHARGGLTARLILGNEDQIIRLRERRMTMDVFLLGFLVAMALYHFTLYFLRKKDAALWY FGTICFVFCFREISTGQNLIQVIVPGISYNVHMRIVYLSFYLLTPITAAFLRALFPEELKKEIYYGIVFISSIFSLIVIS QDPVLFTATIELYYLFTFFCFAIGFYVLMLALIRKKPGAIAILVGMLGIFLSYSQDIFYTKRIIPTFILAPFGLIALIFS EAYLLAKRYSLAFNAVEDMSESLKKINSSYRLFVPKELLKILNKHDILDIKLGDIAEEEMSLLYNEIRTFSDFSEKITGK ENFEFINSFLGKVGPAIRERDGFIDKYFGEAFLALFPPEPEKALESAIEIQRILREFNRERIANGKDPIRSGSGIHTGPI LLGTIGETERMESTVISSSVNVASKIVQLSRTYESSLLITDSTLFRLTNSSEYFYRVVDRIQIRDQRSIYTVLEVLNGLP ENLIDSYMKTREEFEHGILLFREKHFEEACLIFNRILEKNRVDQAARVYLEKSVHNCRFGVPENWQGITLLED >Mature_632_residues PVPKAWTRIQEPNGKNYPGTGIATYFLKVILPENLSSNNLAILAETSETAYEVWIDDNKIGAQGVPGETADTSTPEWNVK ILPFQINKKEFQIRIPLSNFYHARGGLTARLILGNEDQIIRLRERRMTMDVFLLGFLVAMALYHFTLYFLRKKDAALWYF GTICFVFCFREISTGQNLIQVIVPGISYNVHMRIVYLSFYLLTPITAAFLRALFPEELKKEIYYGIVFISSIFSLIVISQ DPVLFTATIELYYLFTFFCFAIGFYVLMLALIRKKPGAIAILVGMLGIFLSYSQDIFYTKRIIPTFILAPFGLIALIFSE AYLLAKRYSLAFNAVEDMSESLKKINSSYRLFVPKELLKILNKHDILDIKLGDIAEEEMSLLYNEIRTFSDFSEKITGKE NFEFINSFLGKVGPAIRERDGFIDKYFGEAFLALFPPEPEKALESAIEIQRILREFNRERIANGKDPIRSGSGIHTGPIL LGTIGETERMESTVISSSVNVASKIVQLSRTYESSLLITDSTLFRLTNSSEYFYRVVDRIQIRDQRSIYTVLEVLNGLPE NLIDSYMKTREEFEHGILLFREKHFEEACLIFNRILEKNRVDQAARVYLEKSVHNCRFGVPENWQGITLLED
Specific function: May function as a membrane-localized receptor protein [H]
COG id: COG2114
COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)
Gene ontology:
Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HAMP domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001054 - InterPro: IPR003660 [H]
Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]
EC number: =4.6.1.1 [H]
Molecular weight: Translated: 72653; Mature: 72522
Theoretical pI: Translated: 6.54; Mature: 6.54
Prosite motif: PS50125 GUANYLATE_CYCLASES_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPVPKAWTRIQEPNGKNYPGTGIATYFLKVILPENLSSNNLAILAETSETAYEVWIDDNK CCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEECCC IGAQGVPGETADTSTPEWNVKILPFQINKKEFQIRIPLSNFYHARGGLTARLILGNEDQI CCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEEEECHHHHHHCCCCCEEEEEECCCCHH IRLRERRMTMDVFLLGFLVAMALYHFTLYFLRKKDAALWYFGTICFVFCFREISTGQNLI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHH QVIVPGISYNVHMRIVYLSFYLLTPITAAFLRALFPEELKKEIYYGIVFISSIFSLIVIS HHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEEC QDPVLFTATIELYYLFTFFCFAIGFYVLMLALIRKKPGAIAILVGMLGIFLSYSQDIFYT CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHH KRIIPTFILAPFGLIALIFSEAYLLAKRYSLAFNAVEDMSESLKKINSSYRLFVPKELLK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH ILNKHDILDIKLGDIAEEEMSLLYNEIRTFSDFSEKITGKENFEFINSFLGKVGPAIRER HHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHH DGFIDKYFGEAFLALFPPEPEKALESAIEIQRILREFNRERIANGKDPIRSGSGIHTGPI CCCHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE LLGTIGETERMESTVISSSVNVASKIVQLSRTYESSLLITDSTLFRLTNSSEYFYRVVDR EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCHHHHHHHHH IQIRDQRSIYTVLEVLNGLPENLIDSYMKTREEFEHGILLFREKHFEEACLIFNRILEKN HHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHH RVDQAARVYLEKSVHNCRFGVPENWQGITLLED HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC >Mature Secondary Structure PVPKAWTRIQEPNGKNYPGTGIATYFLKVILPENLSSNNLAILAETSETAYEVWIDDNK CCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEECCC IGAQGVPGETADTSTPEWNVKILPFQINKKEFQIRIPLSNFYHARGGLTARLILGNEDQI CCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEEEECHHHHHHCCCCCEEEEEECCCCHH IRLRERRMTMDVFLLGFLVAMALYHFTLYFLRKKDAALWYFGTICFVFCFREISTGQNLI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHH QVIVPGISYNVHMRIVYLSFYLLTPITAAFLRALFPEELKKEIYYGIVFISSIFSLIVIS HHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEEC QDPVLFTATIELYYLFTFFCFAIGFYVLMLALIRKKPGAIAILVGMLGIFLSYSQDIFYT CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHH KRIIPTFILAPFGLIALIFSEAYLLAKRYSLAFNAVEDMSESLKKINSSYRLFVPKELLK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH ILNKHDILDIKLGDIAEEEMSLLYNEIRTFSDFSEKITGKENFEFINSFLGKVGPAIRER HHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHH DGFIDKYFGEAFLALFPPEPEKALESAIEIQRILREFNRERIANGKDPIRSGSGIHTGPI CCCHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE LLGTIGETERMESTVISSSVNVASKIVQLSRTYESSLLITDSTLFRLTNSSEYFYRVVDR EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCHHHHHHHHH IQIRDQRSIYTVLEVLNGLPENLIDSYMKTREEFEHGILLFREKHFEEACLIFNRILEKN HHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHH RVDQAARVYLEKSVHNCRFGVPENWQGITLLED HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7601856 [H]