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The map label for this gene is ileS

Identifier: 45359037

GI number: 45359037

Start: 1433443

End: 1436547

Strand: Direct

Name: ileS

Synonym: MMP1474

Alternate gene names: 45359037

Gene position: 1433443-1436547 (Clockwise)

Preceding gene: 45359036

Following gene: 45359040

Centisome position: 86.29

GC content: 34.65

Gene sequence:

>3105_bases
ATGAAACAAGTTAAATCCGTAAATTTTAGAGAATTAGATAAAAAAGTAAAAGAATACTGGAAAAAAGAAAATACCTACAA
AAAAGTAAAAGCATTAAATGAACACGGCCCTGAATACTATTTTGTTGACGGCCCTCCGTACTGTTCTGGTGCAATACACC
TTGGAACAGCTTGGAATAAAATTATAAAGGATACAGTTTTAAGATTTAAGAGAATTCAAGGATACAATGTTTTAGATAAA
GCTGGATGGGATATGCACGGGCTTCCTATCGAAGTTAAAGTGGAAAATGAATTTAACATCGGCTCCAAAAAAGACATTGA
AACAAAAATTGGAACACAAGAATTTATAAACAAATGTAAAGAGTTTGCATTAAATCACCTCGGACATATGCAAGGGCAGT
TTGAAAACTTAGGTGTATGGCTCGATTTTGAAAACGCATACATGCCGATCAAAAGAGACTACATGGAAATGGGCTGGTGG
ACGCTTAAAAAAGCTCATGAAAAAGAATTACTCACAAAAGACTTGAGATCAGGATACTGGTGCCCAAGATGTGAAACTTC
GCTTGCTGAACACGAAGTAAGAGGAGAATACAAAGAAGTACTTGACCCTTCAGTTTATGTAAAATTCAAACTTGAAAAAA
GCGATGAATACATCACAATCTGGACCACTACTCCTTGGACACTTCCTTCAAACATGCTCGTATGTGTAAATCCGGAATTT
GATTACGCTTATGTTAATGTTGAATTTGAAAATGGAACTGCTGAAACATGGATTATTGCTGAAAAATTAGTAAATGACGT
AATGAAAAAGGCTGAAAAAAACAACGACATTTCAAAATTCAGTATTTCAAAAGTAGTTAAAGGAGATTCCTTAATTGGAT
TAAAATACATTCACCCACTCCTTGAAGAAAATGAAAAACAACAAGAATTTGCAAAAATAGAAAATGTGCACACGATTGTT
CCAGGAGACCACGTAACTCTTGAAGGGGGAACGGGTTTAGTTCACACCGCACCAGGATTTGGTGAAGATGACTTTAACAT
TGGTAAAGAACACAACATTCCAGTATACGCACCAATTGATGACAACGGAAAGTATACCGATAGTATCTGGAAAGGAACTT
TTGTAAAAGATATGGATGAATCAGTTATTGAAACATTGATATCCAAAAATTTACTCGTAAACTCTGGAAAAGTAAAACAC
ACCTATCCACACTGCTGGAGATGCAAAACACCACTTTTATTCAGGGCAACTGAACAGTGGTTCCTTTCAATCTCAAAAAT
AAAAGATTCCATCATCGAACAGGGTAAAACTGTTGATTGGGTCCCAGACTGGGTTAAAACAAGATATGTTAACGGAGTAA
GCTTTGTTGGAGACTGGAACATCTCAAGACAGCGATACTGGGGAATTCCGCTTCCAATCTGGATCTGTGAAGAATGTGGA
AATTACGAAGTAATCGGTTCAGTTGATGAATTAAAAGAAAGAGCTAACGAAAAAGATGTAGATTTAAGCGACATCCACAA
ACCTGCCGTTGATAAAATTACGCTTACATGTTCCTGCGGCGGAAAAATGAAAAGAACCCCTGATGTATTAGATGTCTGGT
ACGACAGCGGTTTGGCGCCATATGCGTCAATTGGATCTAAAAAACTTAAAAAAGCTCAATTTATTACCGAAGGAAACGAT
CAGGTTACAAAATGGTTCTACTCACAGCATGCATTGAGTGCAGTTGTATTTGACGATACTTCTTACGAAAAATGTATGAT
GCACGGATTCACTCTTGATGAAACCGGAGAAAAAATGAGTAAATCCTTAGGAAACATTGTAAGTCCTGATGATGTTACAG
AACAGTACGGTGCAGATGTTTTAAGGTTCTACCTTTTAAGTGCAAACAAAGCGTGGGAAGATTTAAGATTTTCATACTCA
GAAATGGATGAAACTAGAAGTATGTTAAATACACTCTGGAATTCATACGCATTCTCTGCAAATTACATGGTTCTTGATGA
TTTCGTTCCAAATAACGAATATTTCAAGCATGTTAAAGATGAAGACGCATGGATATTGAGCAGAATCAATACTGTCGCTA
AAGAAGCTGTTGAAGCTTTAGAAAAACCTCATTTACACGTGTACACATGGGCACTTAGGGATTTCATACTCAACGACTTT
TCAAGATGGTATATTAAATTAATTCGTGACAGAACATGGATGGAGAAAAATGACGTGCAGAAATTATCTGCATACCAGAC
TCTGTACTACGTGATCATGAAATTAATTTCGATAATGGCTCCGGTAACACCTCACCTTTCAGAAGAAATCTATCAAAACT
TAAAAACAGAAGATATGCCTGAAAGCATCTTTATGAACAAGTTAACAATTGAATCTGAATTTATAAATGAAACTTTGGAA
AAAGATACCGAAATTATTCGTGAAATTGTAGATTCAATCCTCAAAGGAAGAGATAAAGCAAAATACACACTAAGATATCC
AATTACAAAAATAACGCTTCCTGAAAACATTGCTGAAACTGTTGAAAAATACGGATATATCATAAAAGAACAGGGCAACG
TAAAAGAAATTGAATTAAAAGAATTTGAAGGAAATATAACAGTAAAACCAAACTTCAAAGAACTTGGAAAAATATTCAGA
AGCGACGTTCCAAAAGTAGTTGCTGCAATAAATTCAGTAGCTCCTAACGAACTAAAAGAAAAATTGAAATCTGGAAACTT
TGAAGTTTCAGAATATGAAATAAAACCAGAATACGTTGAATTCAGGGTTGAAATTCCTGAAAACATTGTCGGTGTTGAAT
TCTCAAAAGGAAACGTTTACATTAACATTGAGATGAACGATGAAGTAATCAAAGAAGGATTGGTTAGAGAAGTTGTTAGA
AGAATCCAATCCATGAGAAAAGATATGGATTTAGATATTAACGAAAAAATCAACGTTAAATTGGAAGGAATTGATTTTAG
TAGTGATTATTTAAGCCATATCGCAAATGAAGTTAGAGGAAACTTCGTTGAAAGTTTAAAATCTGATTACAATCAAAAAT
GGACTATCAAAACGCCAAACGAAGAAACTTACGATATTTCAATCGACATTGAAAAAAATAAATAA

Upstream 100 bases:

>100_bases
GAAAGGGTACTACAAAAGTAAAAGTCTTGATTCAGATGAAGAAATTGAAGAATCACATTAATCTAAATTAAATTATTTTA
AAAATTATCGGGGTGAATAA

Downstream 100 bases:

>100_bases
AATAAAAAAATCTTTTTTTATATTTTTATTATCAATTTACCGGTAGTTTGAGTAGTAATCCGACATATCAATTGCATTCT
CTGCTTCTTTTGGAAGTTCT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1034; Mature: 1034

Protein sequence:

>1034_residues
MKQVKSVNFRELDKKVKEYWKKENTYKKVKALNEHGPEYYFVDGPPYCSGAIHLGTAWNKIIKDTVLRFKRIQGYNVLDK
AGWDMHGLPIEVKVENEFNIGSKKDIETKIGTQEFINKCKEFALNHLGHMQGQFENLGVWLDFENAYMPIKRDYMEMGWW
TLKKAHEKELLTKDLRSGYWCPRCETSLAEHEVRGEYKEVLDPSVYVKFKLEKSDEYITIWTTTPWTLPSNMLVCVNPEF
DYAYVNVEFENGTAETWIIAEKLVNDVMKKAEKNNDISKFSISKVVKGDSLIGLKYIHPLLEENEKQQEFAKIENVHTIV
PGDHVTLEGGTGLVHTAPGFGEDDFNIGKEHNIPVYAPIDDNGKYTDSIWKGTFVKDMDESVIETLISKNLLVNSGKVKH
TYPHCWRCKTPLLFRATEQWFLSISKIKDSIIEQGKTVDWVPDWVKTRYVNGVSFVGDWNISRQRYWGIPLPIWICEECG
NYEVIGSVDELKERANEKDVDLSDIHKPAVDKITLTCSCGGKMKRTPDVLDVWYDSGLAPYASIGSKKLKKAQFITEGND
QVTKWFYSQHALSAVVFDDTSYEKCMMHGFTLDETGEKMSKSLGNIVSPDDVTEQYGADVLRFYLLSANKAWEDLRFSYS
EMDETRSMLNTLWNSYAFSANYMVLDDFVPNNEYFKHVKDEDAWILSRINTVAKEAVEALEKPHLHVYTWALRDFILNDF
SRWYIKLIRDRTWMEKNDVQKLSAYQTLYYVIMKLISIMAPVTPHLSEEIYQNLKTEDMPESIFMNKLTIESEFINETLE
KDTEIIREIVDSILKGRDKAKYTLRYPITKITLPENIAETVEKYGYIIKEQGNVKEIELKEFEGNITVKPNFKELGKIFR
SDVPKVVAAINSVAPNELKEKLKSGNFEVSEYEIKPEYVEFRVEIPENIVGVEFSKGNVYINIEMNDEVIKEGLVREVVR
RIQSMRKDMDLDINEKINVKLEGIDFSSDYLSHIANEVRGNFVESLKSDYNQKWTIKTPNEETYDISIDIEKNK

Sequences:

>Translated_1034_residues
MKQVKSVNFRELDKKVKEYWKKENTYKKVKALNEHGPEYYFVDGPPYCSGAIHLGTAWNKIIKDTVLRFKRIQGYNVLDK
AGWDMHGLPIEVKVENEFNIGSKKDIETKIGTQEFINKCKEFALNHLGHMQGQFENLGVWLDFENAYMPIKRDYMEMGWW
TLKKAHEKELLTKDLRSGYWCPRCETSLAEHEVRGEYKEVLDPSVYVKFKLEKSDEYITIWTTTPWTLPSNMLVCVNPEF
DYAYVNVEFENGTAETWIIAEKLVNDVMKKAEKNNDISKFSISKVVKGDSLIGLKYIHPLLEENEKQQEFAKIENVHTIV
PGDHVTLEGGTGLVHTAPGFGEDDFNIGKEHNIPVYAPIDDNGKYTDSIWKGTFVKDMDESVIETLISKNLLVNSGKVKH
TYPHCWRCKTPLLFRATEQWFLSISKIKDSIIEQGKTVDWVPDWVKTRYVNGVSFVGDWNISRQRYWGIPLPIWICEECG
NYEVIGSVDELKERANEKDVDLSDIHKPAVDKITLTCSCGGKMKRTPDVLDVWYDSGLAPYASIGSKKLKKAQFITEGND
QVTKWFYSQHALSAVVFDDTSYEKCMMHGFTLDETGEKMSKSLGNIVSPDDVTEQYGADVLRFYLLSANKAWEDLRFSYS
EMDETRSMLNTLWNSYAFSANYMVLDDFVPNNEYFKHVKDEDAWILSRINTVAKEAVEALEKPHLHVYTWALRDFILNDF
SRWYIKLIRDRTWMEKNDVQKLSAYQTLYYVIMKLISIMAPVTPHLSEEIYQNLKTEDMPESIFMNKLTIESEFINETLE
KDTEIIREIVDSILKGRDKAKYTLRYPITKITLPENIAETVEKYGYIIKEQGNVKEIELKEFEGNITVKPNFKELGKIFR
SDVPKVVAAINSVAPNELKEKLKSGNFEVSEYEIKPEYVEFRVEIPENIVGVEFSKGNVYINIEMNDEVIKEGLVREVVR
RIQSMRKDMDLDINEKINVKLEGIDFSSDYLSHIANEVRGNFVESLKSDYNQKWTIKTPNEETYDISIDIEKNK
>Mature_1034_residues
MKQVKSVNFRELDKKVKEYWKKENTYKKVKALNEHGPEYYFVDGPPYCSGAIHLGTAWNKIIKDTVLRFKRIQGYNVLDK
AGWDMHGLPIEVKVENEFNIGSKKDIETKIGTQEFINKCKEFALNHLGHMQGQFENLGVWLDFENAYMPIKRDYMEMGWW
TLKKAHEKELLTKDLRSGYWCPRCETSLAEHEVRGEYKEVLDPSVYVKFKLEKSDEYITIWTTTPWTLPSNMLVCVNPEF
DYAYVNVEFENGTAETWIIAEKLVNDVMKKAEKNNDISKFSISKVVKGDSLIGLKYIHPLLEENEKQQEFAKIENVHTIV
PGDHVTLEGGTGLVHTAPGFGEDDFNIGKEHNIPVYAPIDDNGKYTDSIWKGTFVKDMDESVIETLISKNLLVNSGKVKH
TYPHCWRCKTPLLFRATEQWFLSISKIKDSIIEQGKTVDWVPDWVKTRYVNGVSFVGDWNISRQRYWGIPLPIWICEECG
NYEVIGSVDELKERANEKDVDLSDIHKPAVDKITLTCSCGGKMKRTPDVLDVWYDSGLAPYASIGSKKLKKAQFITEGND
QVTKWFYSQHALSAVVFDDTSYEKCMMHGFTLDETGEKMSKSLGNIVSPDDVTEQYGADVLRFYLLSANKAWEDLRFSYS
EMDETRSMLNTLWNSYAFSANYMVLDDFVPNNEYFKHVKDEDAWILSRINTVAKEAVEALEKPHLHVYTWALRDFILNDF
SRWYIKLIRDRTWMEKNDVQKLSAYQTLYYVIMKLISIMAPVTPHLSEEIYQNLKTEDMPESIFMNKLTIESEFINETLE
KDTEIIREIVDSILKGRDKAKYTLRYPITKITLPENIAETVEKYGYIIKEQGNVKEIELKEFEGNITVKPNFKELGKIFR
SDVPKVVAAINSVAPNELKEKLKSGNFEVSEYEIKPEYVEFRVEIPENIVGVEFSKGNVYINIEMNDEVIKEGLVREVVR
RIQSMRKDMDLDINEKINVKLEGIDFSSDYLSHIANEVRGNFVESLKSDYNQKWTIKTPNEETYDISIDIEKNK

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1050, Percent_Identity=30.3809523809524, Blast_Score=496, Evalue=1e-140,
Organism=Homo sapiens, GI94721241, Length=1050, Percent_Identity=30.3809523809524, Blast_Score=496, Evalue=1e-140,
Organism=Homo sapiens, GI46852147, Length=862, Percent_Identity=29.3503480278422, Blast_Score=349, Evalue=9e-96,
Organism=Homo sapiens, GI268370297, Length=831, Percent_Identity=21.2996389891697, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI268370293, Length=831, Percent_Identity=21.2996389891697, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI268370295, Length=802, Percent_Identity=21.9451371571072, Blast_Score=156, Evalue=1e-37,
Organism=Homo sapiens, GI5454158, Length=848, Percent_Identity=21.4622641509434, Blast_Score=134, Evalue=5e-31,
Organism=Escherichia coli, GI2367096, Length=799, Percent_Identity=31.1639549436796, Blast_Score=383, Evalue=1e-107,
Organism=Escherichia coli, GI1790708, Length=850, Percent_Identity=21.8823529411765, Blast_Score=173, Evalue=6e-44,
Organism=Escherichia coli, GI1786861, Length=887, Percent_Identity=19.9549041713641, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17541896, Length=1019, Percent_Identity=30.1275760549558, Blast_Score=463, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI71980946, Length=818, Percent_Identity=28.9731051344743, Blast_Score=304, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17510661, Length=903, Percent_Identity=22.1483942414175, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI72001587, Length=582, Percent_Identity=24.5704467353952, Blast_Score=118, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1035, Percent_Identity=31.1111111111111, Blast_Score=483, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6325217, Length=800, Percent_Identity=29.375, Blast_Score=295, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6321531, Length=808, Percent_Identity=23.019801980198, Blast_Score=167, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6323414, Length=566, Percent_Identity=23.4982332155477, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28574730, Length=1019, Percent_Identity=29.7350343473994, Blast_Score=486, Evalue=1e-137,
Organism=Drosophila melanogaster, GI24668547, Length=1019, Percent_Identity=29.7350343473994, Blast_Score=486, Evalue=1e-137,
Organism=Drosophila melanogaster, GI24668543, Length=1019, Percent_Identity=29.7350343473994, Blast_Score=486, Evalue=1e-137,
Organism=Drosophila melanogaster, GI281366294, Length=781, Percent_Identity=30.3457106274008, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI17864482, Length=972, Percent_Identity=21.0905349794239, Blast_Score=162, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24653289, Length=972, Percent_Identity=21.0905349794239, Blast_Score=162, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21355675, Length=882, Percent_Identity=20.8616780045351, Blast_Score=138, Evalue=2e-32,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_METMP (Q6LX78)

Other databases:

- EMBL:   BX950229
- RefSeq:   NP_988594.1
- ProteinModelPortal:   Q6LX78
- SMR:   Q6LX78
- GeneID:   2761573
- GenomeReviews:   BX950229_GR
- KEGG:   mmp:MMP1474
- NMPDR:   fig|267377.1.peg.1474
- HOGENOM:   HBG577712
- OMA:   DCHGLPA
- ProtClustDB:   PRK06039
- BioCyc:   MMAR267377:MMP1474-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 119911; Mature: 119911

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 601-601

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVKSVNFRELDKKVKEYWKKENTYKKVKALNEHGPEYYFVDGPPYCSGAIHLGTAWNK
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEECHHHHH
IIKDTVLRFKRIQGYNVLDKAGWDMHGLPIEVKVENEFNIGSKKDIETKIGTQEFINKCK
HHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHCCHHHHHHHHH
EFALNHLGHMQGQFENLGVWLDFENAYMPIKRDYMEMGWWTLKKAHEKELLTKDLRSGYW
HHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
CPRCETSLAEHEVRGEYKEVLDPSVYVKFKLEKSDEYITIWTTTPWTLPSNMLVCVNPEF
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCCCCEEEEECCCC
DYAYVNVEFENGTAETWIIAEKLVNDVMKKAEKNNDISKFSISKVVKGDSLIGLKYIHPL
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEHHHHHHHH
LEENEKQQEFAKIENVHTIVPGDHVTLEGGTGLVHTAPGFGEDDFNIGKEHNIPVYAPID
HHCCHHHHHHHHHHCCEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCEEEEEC
DNGKYTDSIWKGTFVKDMDESVIETLISKNLLVNSGKVKHTYPHCWRCKTPLLFRATEQW
CCCCCCCHHHCCCHHHHHHHHHHHHHHHCCEEECCCCEEECCCCCCCCCCCCEEEECHHH
FLSISKIKDSIIEQGKTVDWVPDWVKTRYVNGVSFVGDWNISRQRYWGIPLPIWICEECG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCEECCCCCCHHHHCCCC
NYEVIGSVDELKERANEKDVDLSDIHKPAVDKITLTCSCGGKMKRTPDVLDVWYDSGLAP
CEEEECCHHHHHHHCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCC
YASIGSKKLKKAQFITEGNDQVTKWFYSQHALSAVVFDDTSYEKCMMHGFTLDETGEKMS
HHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHCCCCCCHHHHHHH
KSLGNIVSPDDVTEQYGADVLRFYLLSANKAWEDLRFSYSEMDETRSMLNTLWNSYAFSA
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHEECC
NYMVLDDFVPNNEYFKHVKDEDAWILSRINTVAKEAVEALEKPHLHVYTWALRDFILNDF
CEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHH
SRWYIKLIRDRTWMEKNDVQKLSAYQTLYYVIMKLISIMAPVTPHLSEEIYQNLKTEDMP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
ESIFMNKLTIESEFINETLEKDTEIIREIVDSILKGRDKAKYTLRYPITKITLPENIAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCHHHHHH
VEKYGYIIKEQGNVKEIELKEFEGNITVKPNFKELGKIFRSDVPKVVAAINSVAPNELKE
HHHCCEEEECCCCEEEEEEEECCCCEEECCCHHHHHHHHHHCHHHHHHHHHCCCHHHHHH
KLKSGNFEVSEYEIKPEYVEFRVEIPENIVGVEFSKGNVYINIEMNDEVIKEGLVREVVR
HHHCCCCEEEEEEECCCEEEEEEECCCCEEEEEEECCEEEEEEEECHHHHHHHHHHHHHH
RIQSMRKDMDLDINEKINVKLEGIDFSSDYLSHIANEVRGNFVESLKSDYNQKWTIKTPN
HHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
EETYDISIDIEKNK
CCEEEEEEEEECCC
>Mature Secondary Structure
MKQVKSVNFRELDKKVKEYWKKENTYKKVKALNEHGPEYYFVDGPPYCSGAIHLGTAWNK
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEECHHHHH
IIKDTVLRFKRIQGYNVLDKAGWDMHGLPIEVKVENEFNIGSKKDIETKIGTQEFINKCK
HHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHCCHHHHHHHHH
EFALNHLGHMQGQFENLGVWLDFENAYMPIKRDYMEMGWWTLKKAHEKELLTKDLRSGYW
HHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
CPRCETSLAEHEVRGEYKEVLDPSVYVKFKLEKSDEYITIWTTTPWTLPSNMLVCVNPEF
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCCCCEEEEECCCC
DYAYVNVEFENGTAETWIIAEKLVNDVMKKAEKNNDISKFSISKVVKGDSLIGLKYIHPL
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEHHHHHHHH
LEENEKQQEFAKIENVHTIVPGDHVTLEGGTGLVHTAPGFGEDDFNIGKEHNIPVYAPID
HHCCHHHHHHHHHHCCEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCEEEEEC
DNGKYTDSIWKGTFVKDMDESVIETLISKNLLVNSGKVKHTYPHCWRCKTPLLFRATEQW
CCCCCCCHHHCCCHHHHHHHHHHHHHHHCCEEECCCCEEECCCCCCCCCCCCEEEECHHH
FLSISKIKDSIIEQGKTVDWVPDWVKTRYVNGVSFVGDWNISRQRYWGIPLPIWICEECG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCEECCCCCCHHHHCCCC
NYEVIGSVDELKERANEKDVDLSDIHKPAVDKITLTCSCGGKMKRTPDVLDVWYDSGLAP
CEEEECCHHHHHHHCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCC
YASIGSKKLKKAQFITEGNDQVTKWFYSQHALSAVVFDDTSYEKCMMHGFTLDETGEKMS
HHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHCCCCCCHHHHHHH
KSLGNIVSPDDVTEQYGADVLRFYLLSANKAWEDLRFSYSEMDETRSMLNTLWNSYAFSA
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHEECC
NYMVLDDFVPNNEYFKHVKDEDAWILSRINTVAKEAVEALEKPHLHVYTWALRDFILNDF
CEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHH
SRWYIKLIRDRTWMEKNDVQKLSAYQTLYYVIMKLISIMAPVTPHLSEEIYQNLKTEDMP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
ESIFMNKLTIESEFINETLEKDTEIIREIVDSILKGRDKAKYTLRYPITKITLPENIAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCHHHHHH
VEKYGYIIKEQGNVKEIELKEFEGNITVKPNFKELGKIFRSDVPKVVAAINSVAPNELKE
HHHCCEEEECCCCEEEEEEEECCCCEEECCCHHHHHHHHHHCHHHHHHHHHCCCHHHHHH
KLKSGNFEVSEYEIKPEYVEFRVEIPENIVGVEFSKGNVYINIEMNDEVIKEGLVREVVR
HHHCCCCEEEEEEECCCEEEEEEECCCCEEEEEEECCEEEEEEEECHHHHHHHHHHHHHH
RIQSMRKDMDLDINEKINVKLEGIDFSSDYLSHIANEVRGNFVESLKSDYNQKWTIKTPN
HHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
EETYDISIDIEKNK
CCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA