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The map label for this gene is 45358988

Identifier: 45358988

GI number: 45358988

Start: 1398277

End: 1398816

Strand: Direct

Name: 45358988

Synonym: MMP1425

Alternate gene names: NA

Gene position: 1398277-1398816 (Clockwise)

Preceding gene: 45358987

Following gene: 45358989

Centisome position: 84.18

GC content: 37.04

Gene sequence:

>540_bases
ATGGCTATTGAGATATTGAGGTTGGGCCATCGAGGCGAGAGAGACAAGAGAATATCTACCCACGTTGCACTAACTTCAAG
AGCACTGGGGGCTGAAAAGATAATATTTACTGAAGAGGATAAACACGTTAAAGAAAGCGTTGAAAGAATTGTTGAAGCTT
GGGGCGGAGAATTTAAATTTGAAGTCGTCAAATCCTGGAGATCTTATGCAAAAAGGTTTAAAGATAACGGGATAGTAGTA
CATCTTACAATGTATGGGGAAAATATTAATAAAATTATGACAGAGATTAGAGAAGATATTTCAAAAACGAATAAAAACTT
GCTTTTGATAATTGGTGCTGAAAAAGTTCCAAGAGAAGCTTACGATCTTGCAGACTACAACCTTTCAGTTGGAAACCAGC
CCCATTCTGAAGTTGCGGCACTTGCAATATTCCTGGACCGATTTACCGAAGGAAAAACACTTTATTCTGAGTATGATGAT
GCCAAAATAAAAGTAACACCTTCAAAATCCGAAAAGTGTGTTTTTGTAGAAAAGGACTAA

Upstream 100 bases:

>100_bases
TTTTTTTAACATTTCAATTAATTTTAAATATTAACTTTTTTAATATTTTTTGAAAACTTTTAATTTAACTCGAATTTTAT
TTGATTAATTTGGTGATTTT

Downstream 100 bases:

>100_bases
TCTAAATCTCTCTGGTGAAATAGATGATATTAAGTGATAAAGACATTTTTAATTATGTTACTTCAAAAAGAGTTTTAATT
GAGCCTTTCAACTCAAAATT

Product: tRNA 2'-O-methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MAIEILRLGHRGERDKRISTHVALTSRALGAEKIIFTEEDKHVKESVERIVEAWGGEFKFEVVKSWRSYAKRFKDNGIVV
HLTMYGENINKIMTEIREDISKTNKNLLLIIGAEKVPREAYDLADYNLSVGNQPHSEVAALAIFLDRFTEGKTLYSEYDD
AKIKVTPSKSEKCVFVEKD

Sequences:

>Translated_179_residues
MAIEILRLGHRGERDKRISTHVALTSRALGAEKIIFTEEDKHVKESVERIVEAWGGEFKFEVVKSWRSYAKRFKDNGIVV
HLTMYGENINKIMTEIREDISKTNKNLLLIIGAEKVPREAYDLADYNLSVGNQPHSEVAALAIFLDRFTEGKTLYSEYDD
AKIKVTPSKSEKCVFVEKD
>Mature_178_residues
AIEILRLGHRGERDKRISTHVALTSRALGAEKIIFTEEDKHVKESVERIVEAWGGEFKFEVVKSWRSYAKRFKDNGIVVH
LTMYGENINKIMTEIREDISKTNKNLLLIIGAEKVPREAYDLADYNLSVGNQPHSEVAALAIFLDRFTEGKTLYSEYDDA
KIKVTPSKSEKCVFVEKD

Specific function: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs [H]

COG id: COG1303

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aTrm56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002845
- ProDom:   PD016584 [H]

Pfam domain/function: PF01994 DUF127 [H]

EC number: NA

Molecular weight: Translated: 20478; Mature: 20346

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEILRLGHRGERDKRISTHVALTSRALGAEKIIFTEEDKHVKESVERIVEAWGGEFKF
CEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCHH
EVVKSWRSYAKRFKDNGIVVHLTMYGENINKIMTEIREDISKTNKNLLLIIGAEKVPREA
HHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
YDLADYNLSVGNQPHSEVAALAIFLDRFTEGKTLYSEYDDAKIKVTPSKSEKCVFVEKD
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCEEEECCCCCCCEEEEECC
>Mature Secondary Structure 
AIEILRLGHRGERDKRISTHVALTSRALGAEKIIFTEEDKHVKESVERIVEAWGGEFKF
EEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCHH
EVVKSWRSYAKRFKDNGIVVHLTMYGENINKIMTEIREDISKTNKNLLLIIGAEKVPREA
HHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
YDLADYNLSVGNQPHSEVAALAIFLDRFTEGKTLYSEYDDAKIKVTPSKSEKCVFVEKD
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCEEEECCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA