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The map label for this gene is aroC [H]

Identifier: 45358896

GI number: 45358896

Start: 1313078

End: 1314199

Strand: Direct

Name: aroC [H]

Synonym: MMP1333

Alternate gene names: 45358896

Gene position: 1313078-1314199 (Clockwise)

Preceding gene: 45358892

Following gene: 45358897

Centisome position: 79.05

GC content: 34.67

Gene sequence:

>1122_bases
TTGAACACTTTTGGGGATAATTTTAGAGTAACGACATGGGGAGAAAGCCACGGAAAAGCATTAGGTGCAGTAATTGACGG
ATGTCCTGCAAATCTACCCATTTTAGAAGAAGATATTCAAAATGAATTGAATAGAAGAAGACCCGGATACAGTATATTCT
CAACACCGCGAAAAGAAGAAGATATGTTGGAAATTCTTTCAGGGATATTTGAAGGAAAAACTACAGGAACACCGATTTCA
GGACTTGTATTTAACAAAGGACAAAAATCAAAAGATTACAGTAAAATTAAAGATACCCCAAGACCGGGACATGCTGATTT
AAACTACTTTTTAAAGTACGGAAACTACGACTACAGGGGCGGCGGAAGAAGTAGCGGAAGAACCACGATTGGAAACGTGA
TTGGTGGAGCAGTTGCTAAAAAATTAATTGAATTTACGCACAATATTAAAATAATCGGTTACTCTACAAAAATTGGAAAA
ATAAATGGAGATTTTGATTACTATAAAAACCCAGAATTCTTTGAAAGTGATTCAAATATCGAAAAATTATTTGAAAAAAC
GGAAAATAACCCCTTAAGATGTCCTTCAAAAAATAGCGATGAAATGAAAGATTATGTACTTGACGCAATGGATAAAAAGG
ACAGTGTTGGAGGAATAATTGAAATAATTATAAAAGGAATTCCGCAAGGCGTTGGAAATCCAGTATTCAATAAATTAGAA
GGAAAACTAGGAAGTGCATTCATTGGAATTAACGCAGTGAAAGGATTTGAAATAGGTCGTGGTTTTGAATCTTCAGACCT
TTATGGAAGCGAAATGAATGACGAATATTATATTGATGAAAATTCAATAAATGAAAAAACTAACAATGCTGGAGGAATTA
TCGGCGGAATTAGTACCGGTTCTCCAGTTGTCCTTAGAGTTTCGATAAAACCCACTCCCTCAATTTCAAAAATTCAAGAC
AGTGTAAATTTAATATCAAATGAAAATGAAAAAATCGAAATTGGTGGCCGACACGACCCGATAATCGTTCCAAGAGTAAT
TCCAGTACTTGAATCAATGGCTGCAATAACAGTTGCAGATTTAATGATTTCAGGTGGATATATTAACCCCTGCAGACTAT
AA

Upstream 100 bases:

>100_bases
CCTACAACTGCAATCATAATCCATCCCCTCATTTTTTAAACCAGTATATCTAATGTATTGAATGTATTATGTTTATATCT
TACGAAATCACGGTGATACA

Downstream 100 bases:

>100_bases
AACCAATAAAAAAACTTTTAATTCTTTTAAAAAATAATAAAAAAAGCGGATGCAGAACTCAATCCAAAAAATCCAACATC
CTAACGTATAATCCCCATTA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MNTFGDNFRVTTWGESHGKALGAVIDGCPANLPILEEDIQNELNRRRPGYSIFSTPRKEEDMLEILSGIFEGKTTGTPIS
GLVFNKGQKSKDYSKIKDTPRPGHADLNYFLKYGNYDYRGGGRSSGRTTIGNVIGGAVAKKLIEFTHNIKIIGYSTKIGK
INGDFDYYKNPEFFESDSNIEKLFEKTENNPLRCPSKNSDEMKDYVLDAMDKKDSVGGIIEIIIKGIPQGVGNPVFNKLE
GKLGSAFIGINAVKGFEIGRGFESSDLYGSEMNDEYYIDENSINEKTNNAGGIIGGISTGSPVVLRVSIKPTPSISKIQD
SVNLISNENEKIEIGGRHDPIIVPRVIPVLESMAAITVADLMISGGYINPCRL

Sequences:

>Translated_373_residues
MNTFGDNFRVTTWGESHGKALGAVIDGCPANLPILEEDIQNELNRRRPGYSIFSTPRKEEDMLEILSGIFEGKTTGTPIS
GLVFNKGQKSKDYSKIKDTPRPGHADLNYFLKYGNYDYRGGGRSSGRTTIGNVIGGAVAKKLIEFTHNIKIIGYSTKIGK
INGDFDYYKNPEFFESDSNIEKLFEKTENNPLRCPSKNSDEMKDYVLDAMDKKDSVGGIIEIIIKGIPQGVGNPVFNKLE
GKLGSAFIGINAVKGFEIGRGFESSDLYGSEMNDEYYIDENSINEKTNNAGGIIGGISTGSPVVLRVSIKPTPSISKIQD
SVNLISNENEKIEIGGRHDPIIVPRVIPVLESMAAITVADLMISGGYINPCRL
>Mature_373_residues
MNTFGDNFRVTTWGESHGKALGAVIDGCPANLPILEEDIQNELNRRRPGYSIFSTPRKEEDMLEILSGIFEGKTTGTPIS
GLVFNKGQKSKDYSKIKDTPRPGHADLNYFLKYGNYDYRGGGRSSGRTTIGNVIGGAVAKKLIEFTHNIKIIGYSTKIGK
INGDFDYYKNPEFFESDSNIEKLFEKTENNPLRCPSKNSDEMKDYVLDAMDKKDSVGGIIEIIIKGIPQGVGNPVFNKLE
GKLGSAFIGINAVKGFEIGRGFESSDLYGSEMNDEYYIDENSINEKTNNAGGIIGGISTGSPVVLRVSIKPTPSISKIQD
SVNLISNENEKIEIGGRHDPIIVPRVIPVLESMAAITVADLMISGGYINPCRL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=363, Percent_Identity=43.801652892562, Blast_Score=276, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=42.2343324250681, Blast_Score=295, Evalue=7e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 40809; Mature: 40809

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTFGDNFRVTTWGESHGKALGAVIDGCPANLPILEEDIQNELNRRRPGYSIFSTPRKEE
CCCCCCCCEEEECCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHH
DMLEILSGIFEGKTTGTPISGLVFNKGQKSKDYSKIKDTPRPGHADLNYFLKYGNYDYRG
HHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHCCCCCCCCCCCEEEEEECCEEECC
GGRSSGRTTIGNVIGGAVAKKLIEFTHNIKIIGYSTKIGKINGDFDYYKNPEFFESDSNI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECEECCCCCCCCCCCCCCCCCCCCHH
EKLFEKTENNPLRCPSKNSDEMKDYVLDAMDKKDSVGGIIEIIIKGIPQGVGNPVFNKLE
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GKLGSAFIGINAVKGFEIGRGFESSDLYGSEMNDEYYIDENSINEKTNNAGGIIGGISTG
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCC
SPVVLRVSIKPTPSISKIQDSVNLISNENEKIEIGGRHDPIIVPRVIPVLESMAAITVAD
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHH
LMISGGYINPCRL
HHHCCCCCCCCCC
>Mature Secondary Structure
MNTFGDNFRVTTWGESHGKALGAVIDGCPANLPILEEDIQNELNRRRPGYSIFSTPRKEE
CCCCCCCCEEEECCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHH
DMLEILSGIFEGKTTGTPISGLVFNKGQKSKDYSKIKDTPRPGHADLNYFLKYGNYDYRG
HHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHCCCCCCCCCCCEEEEEECCEEECC
GGRSSGRTTIGNVIGGAVAKKLIEFTHNIKIIGYSTKIGKINGDFDYYKNPEFFESDSNI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECEECCCCCCCCCCCCCCCCCCCCHH
EKLFEKTENNPLRCPSKNSDEMKDYVLDAMDKKDSVGGIIEIIIKGIPQGVGNPVFNKLE
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GKLGSAFIGINAVKGFEIGRGFESSDLYGSEMNDEYYIDENSINEKTNNAGGIIGGISTG
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCC
SPVVLRVSIKPTPSISKIQDSVNLISNENEKIEIGGRHDPIIVPRVIPVLESMAAITVAD
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHH
LMISGGYINPCRL
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA