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The map label for this gene is rpoD [H]

Identifier: 45358885

GI number: 45358885

Start: 1307356

End: 1307898

Strand: Direct

Name: rpoD [H]

Synonym: MMP1322

Alternate gene names: 45358885

Gene position: 1307356-1307898 (Clockwise)

Preceding gene: 45358884

Following gene: 45358886

Centisome position: 78.7

GC content: 32.41

Gene sequence:

>543_bases
ATGAAAATGGAATTAAAAGCCCCTTTATCTTTTTCCAGTGCATTGAGAAGAATAATGATTTCAGAAGTTCCTACATATGC
TATTGAAAATGTATACTTTTATGAAAACACATCTTCAATGTACGATGAAGTTCTAGCTCACAGACTTGGATTAATTCCAA
TAAAAGGAGTTCCGGTAAGTGGTGATGAAGTTATAGTACTTACAATATCCAAAGAAGGACCTTGTACAGTATATTCATCA
GATTTAAAATCAGAATCCGGTGAGCCTGCTTTTGAAAATATTCCTATAGTAAAATTAGCAGAAGACCAGAAACTTGAGTT
AGAAACCGAAGCTCTTGTTGGCACAGGAAAAATTCATGCAAAATGGCAACCCTGCAATGCAAGTTACAAACAAATATCAA
ATGACGAAGTGGAATTTAAAATTGAGTCATTCGGAAACATGGATGCTGAAGACATTATAAGATCTTCACTTGAAATTTTA
AAAAATAAAGCTGAAAAATTCTTATTAGAATTAGAAGGCCAAGAATTAAGTGACGAAAATTAA

Upstream 100 bases:

>100_bases
AATTCCACACGATGGTACTACACCAAAAAGAAAGAACAGATAATTGGTGATTTTTTTGATAAAAAATATCCAAAAAGAGG
AAAAGAGAATAGGGGAAATC

Downstream 100 bases:

>100_bases
TTACTCTTTCTTCCAAATTATTGGAAATTATGAATCAATATCATAAGGGTGAATTTATGAAAAAAATCATGTCAACAAAC
CCAAAAACTCCTGAATTGAT

Product: DNA-directed RNA polymerase subunit D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKMELKAPLSFSSALRRIMISEVPTYAIENVYFYENTSSMYDEVLAHRLGLIPIKGVPVSGDEVIVLTISKEGPCTVYSS
DLKSESGEPAFENIPIVKLAEDQKLELETEALVGTGKIHAKWQPCNASYKQISNDEVEFKIESFGNMDAEDIIRSSLEIL
KNKAEKFLLELEGQELSDEN

Sequences:

>Translated_180_residues
MKMELKAPLSFSSALRRIMISEVPTYAIENVYFYENTSSMYDEVLAHRLGLIPIKGVPVSGDEVIVLTISKEGPCTVYSS
DLKSESGEPAFENIPIVKLAEDQKLELETEALVGTGKIHAKWQPCNASYKQISNDEVEFKIESFGNMDAEDIIRSSLEIL
KNKAEKFLLELEGQELSDEN
>Mature_180_residues
MKMELKAPLSFSSALRRIMISEVPTYAIENVYFYENTSSMYDEVLAHRLGLIPIKGVPVSGDEVIVLTISKEGPCTVYSS
DLKSESGEPAFENIPIVKLAEDQKLELETEALVGTGKIHAKWQPCNASYKQISNDEVEFKIESFGNMDAEDIIRSSLEIL
KNKAEKFLLELEGQELSDEN

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0202

COG function: function code K; DNA-directed RNA polymerase, alpha subunit/40 kD subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal rpoD/eukaryotic RPB3 RNA polymerase subunit family [H]

Homologues:

Organism=Caenorhabditis elegans, GI25155095, Length=183, Percent_Identity=31.6939890710383, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6325367, Length=169, Percent_Identity=34.3195266272189, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322168, Length=149, Percent_Identity=34.8993288590604, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI20129237, Length=165, Percent_Identity=32.1212121212121, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001514
- InterPro:   IPR011261
- InterPro:   IPR011262
- InterPro:   IPR009025
- InterPro:   IPR011263
- InterPro:   IPR022842 [H]

Pfam domain/function: PF01000 RNA_pol_A_bac; PF01193 RNA_pol_L [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 20138; Mature: 20138

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMELKAPLSFSSALRRIMISEVPTYAIENVYFYENTSSMYDEVLAHRLGLIPIKGVPVS
CCCCCCCCCCHHHHHHHHHHHHCCCHHHCEEEEEECCHHHHHHHHHHHCCCEEECCCCCC
GDEVIVLTISKEGPCTVYSSDLKSESGEPAFENIPIVKLAEDQKLELETEALVGTGKIHA
CCCEEEEEECCCCCEEEEECCCCCCCCCCCHHCCCEEEECCCCCEEEEHHEEEECCEEEE
KWQPCNASYKQISNDEVEFKIESFGNMDAEDIIRSSLEILKNKAEKFLLELEGQELSDEN
EECCCCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCC
>Mature Secondary Structure
MKMELKAPLSFSSALRRIMISEVPTYAIENVYFYENTSSMYDEVLAHRLGLIPIKGVPVS
CCCCCCCCCCHHHHHHHHHHHHCCCHHHCEEEEEECCHHHHHHHHHHHCCCEEECCCCCC
GDEVIVLTISKEGPCTVYSSDLKSESGEPAFENIPIVKLAEDQKLELETEALVGTGKIHA
CCCEEEEEECCCCCEEEEECCCCCCCCCCCHHCCCEEEECCCCCEEEEHHEEEECCEEEE
KWQPCNASYKQISNDEVEFKIESFGNMDAEDIIRSSLEILKNKAEKFLLELEGQELSDEN
EECCCCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]