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The map label for this gene is secA

Identifier: 42521895

GI number: 42521895

Start: 258157

End: 260826

Strand: Direct

Name: secA

Synonym: Bd0272

Alternate gene names: 42521895

Gene position: 258157-260826 (Clockwise)

Preceding gene: 42521894

Following gene: 42521896

Centisome position: 6.82

GC content: 49.89

Gene sequence:

>2670_bases
ATGGTTACACAAATTTTGACAAAAATGTTCGGAACGAAGCACGACCGTGAGATGAAAAAGATCCAGCCCACCGTGGATCG
TATCAATGCCCTGGAACCTCAGATGGCAGCCCTTACGGATGATCAACTCAAAGCCAAAACTCCTGAGTTTCAAGAGAGAC
TGAAGAAGGGCGAAACAGTTCACGATATCCTGCCGGAAGCATTCGCGGTTTGCCGTGAAGCCTCCAAGCGTGTGTTGGGA
ATGCGCCACTATGACGTTCAGTTGATCGGTGGTTATGTTCTGAATCGCGGCAACATCGCCGAGATGAGAACGGGTGAAGG
TAAAACCCTGGTGGCGACTTTGCCGGTTTACCTGAATGCTCTTACGGGCCGCGGTGTTCACGTTGTGACTGTGAATGACT
ATCTGGTTCGTCGTGATGCTGAGCACATGGGTCGTCTTTATGGCTGGCTGGGTCTTACCACGGGTATCATCGTTCACGGT
CTGACAGATCAGCAGCGCAAACAGATGTACGCTTGTGACATCACTTATTGCACCAACAATGAACTTGGTTTCGACTATCT
TCGCGACAACATGAAGTTTGATTTGAACGACTATGTTCAAAGACCTCACTATTATGCCATCGTCGATGAGTGCGACTCCA
TCCTGGTCGATGAAGCGCGTACGCCGCTGATCATTTCCGGTCCTGCGGAATCCTCCACTGACAAATACTATGCTGTGAAT
CAGATCATCCCGCACCTGAAGCGCGATGTTCACTTCACCATGGAGGAAAAATCCAAAACAGCCTCCCTGACTGACGCCGG
AAACGCGAAAGTCGAAGAGCTGATGGGACTTTCCAATCTTTATGATCCACAAAACATCGAGATCCTGCACCACGTGTATC
AGGGCCTGAAAGCTCACTATCTGTATCGTCTTGATGTGGAATACATGATCAAAGACGGCGAGATCGTGATCGTCGATGAA
TTCACCGGACGTTTGATGCCAGGTCGTCGCTGGAGCGATGGTCTGCACCAGGCGATTGAAGCCAAAGAAGGCGTTGAAGT
GAAGTCTGAGAATCAGACTTTGGCGACCATCACCTTCCAGAACTATTTCCGTATGTACGAAAAACTGTCTGGTATGACCG
GTACGGCAGATACTGAAGCGGTGGAGTTCAAGAAAATCTACAATCTTGAAGTGAACGTGATTCCGACCAACCGTCCGATC
CAGCGTAAAGATCAGGAAGACGTGGTCTACAAATCAGAAAAAGCGAAATTCAAAGCCATCACCGCCGACATCAAAGAGCG
TATGGCCAAGGGTCAGCCGATTCTGGTGGGTACTGAATCCATCGAAAAATCCGAAGCTTTGAGTGCGTTCCTGCGCAAAG
AGGGTGTTAAGCACGAAGTTCTGAATGCAAAACACCACGAACGTGAAGCGGAAATCATCGCGCAGGCGGGCCGCAAAGGG
GCTGTGACCATCGCCACCAATATGGCGGGTCGTGGTACTGACATCATGCTGGGCGGTAACGCTGACATGCTGGCAAAAGC
TCAGGTGGGCAATGATGATTCTCCGGAATTCGCGGAAGCGGTTCAGAAAATCAAACCTCAGGTTGAAGCCGAGCGTGCGG
AAGTTCGCTCTGTGGGTGGTTTGTACATTATCGGTACTGAACGTCACGAATCTCGCCGTATCGACAACCAGCTGCGGGGT
CGTTCCGGTCGTCAAGGGGATCCGGGTGAATCCAGATTCTATCTGTCTTTGGAAGACAAACTGATGAGAATCTTCAACGG
TGAGCGCATCCAGAAGATCATGGAAATGCTGAACATCCCTGAAGATGAACCAATCACAGCTAAAATGGTGACCAACGCGA
TCGAAGGCGCTCAACGCAAGGTCGAAGGTCACAACTTTGATATCCGTAAAAACCTGATGGAATACGACTCTGTGATGAAT
GCGCAGAGAAACGCCATCTACGGCATGCGCCGCAAGGTTCTGGAGGGTCAGGAAATCGAAAGAACCACTTTGGACTGGCT
TGGTGATGTTGTTTCCAATCTGCTGGATACGCACATCCCTGAAGGTGGAAAAAAAGAAGAGTGGAGCCTGGAAGGCCTGA
ACAACTCTCTGGCACAAAGCTTCGGTTTCAAAATCGACTTTGCGACCATGGCGGTGAACACCGAGACGGTCACGGACGCG
GTGAAGTCCGGTGTGAAGGAAGTTTGGGAACGTCAGAAAAATTCCATGGGTCCGTTCTTTGAACAGGTTCAGAAGATGAT
CCTTCTTCAAAGCATCGATCACCACTGGAAGAACCACTTGTACGTGATCGACAAACTGAAAGAGGGTATCTCTTTGCGCG
GTTACGCACAGAAAGACCCTTTGATCGAGTACAAAAAAGAGGCGTTCAAAGCCTTTGAAACTTTGAACAACACCATCAAG
TCTGATGCGATCGAAAAAGTGATGCGCGTTCAGCTGGTGGCTCAGCAAAACGAGCAGGAAGTTTTGGAAAGCCTGCGTCC
GGAAGAAGCGGACCTGGATGAGTTGGATTATTCATCTCCTAGCGAAGCGGACATCGGTCACAGTATTCCTGAGACTTCTG
AAGATGCTCCAAAGCGCAAGATGACCTTCCAAAGCGGCCCGCGTGATGATCGTCCCATGAACCGCGAAGAGCGTCGTCGT
ATGGACAAAGACACGAAGGGAAAAAGATAA

Upstream 100 bases:

>100_bases
GAAGTCTTTGAAATTCTGAATGAAATCGCGTCAATGACGCATCCAGAAATTGCCCCCTTACCTTGCCGCCTCTGTCAATT
TGGGTCTATCCTCTTAGGCT

Downstream 100 bases:

>100_bases
TTGGCTTCTTGTCCAAGTTGCCACCAGCCGGTAGAGATTCTTGATAAGCATCTGGGGACTCTTTTCACGTGTTCCCACTG
CAATGCGGTTTTCTTTGTCG

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 889; Mature: 889

Protein sequence:

>889_residues
MVTQILTKMFGTKHDREMKKIQPTVDRINALEPQMAALTDDQLKAKTPEFQERLKKGETVHDILPEAFAVCREASKRVLG
MRHYDVQLIGGYVLNRGNIAEMRTGEGKTLVATLPVYLNALTGRGVHVVTVNDYLVRRDAEHMGRLYGWLGLTTGIIVHG
LTDQQRKQMYACDITYCTNNELGFDYLRDNMKFDLNDYVQRPHYYAIVDECDSILVDEARTPLIISGPAESSTDKYYAVN
QIIPHLKRDVHFTMEEKSKTASLTDAGNAKVEELMGLSNLYDPQNIEILHHVYQGLKAHYLYRLDVEYMIKDGEIVIVDE
FTGRLMPGRRWSDGLHQAIEAKEGVEVKSENQTLATITFQNYFRMYEKLSGMTGTADTEAVEFKKIYNLEVNVIPTNRPI
QRKDQEDVVYKSEKAKFKAITADIKERMAKGQPILVGTESIEKSEALSAFLRKEGVKHEVLNAKHHEREAEIIAQAGRKG
AVTIATNMAGRGTDIMLGGNADMLAKAQVGNDDSPEFAEAVQKIKPQVEAERAEVRSVGGLYIIGTERHESRRIDNQLRG
RSGRQGDPGESRFYLSLEDKLMRIFNGERIQKIMEMLNIPEDEPITAKMVTNAIEGAQRKVEGHNFDIRKNLMEYDSVMN
AQRNAIYGMRRKVLEGQEIERTTLDWLGDVVSNLLDTHIPEGGKKEEWSLEGLNNSLAQSFGFKIDFATMAVNTETVTDA
VKSGVKEVWERQKNSMGPFFEQVQKMILLQSIDHHWKNHLYVIDKLKEGISLRGYAQKDPLIEYKKEAFKAFETLNNTIK
SDAIEKVMRVQLVAQQNEQEVLESLRPEEADLDELDYSSPSEADIGHSIPETSEDAPKRKMTFQSGPRDDRPMNREERRR
MDKDTKGKR

Sequences:

>Translated_889_residues
MVTQILTKMFGTKHDREMKKIQPTVDRINALEPQMAALTDDQLKAKTPEFQERLKKGETVHDILPEAFAVCREASKRVLG
MRHYDVQLIGGYVLNRGNIAEMRTGEGKTLVATLPVYLNALTGRGVHVVTVNDYLVRRDAEHMGRLYGWLGLTTGIIVHG
LTDQQRKQMYACDITYCTNNELGFDYLRDNMKFDLNDYVQRPHYYAIVDECDSILVDEARTPLIISGPAESSTDKYYAVN
QIIPHLKRDVHFTMEEKSKTASLTDAGNAKVEELMGLSNLYDPQNIEILHHVYQGLKAHYLYRLDVEYMIKDGEIVIVDE
FTGRLMPGRRWSDGLHQAIEAKEGVEVKSENQTLATITFQNYFRMYEKLSGMTGTADTEAVEFKKIYNLEVNVIPTNRPI
QRKDQEDVVYKSEKAKFKAITADIKERMAKGQPILVGTESIEKSEALSAFLRKEGVKHEVLNAKHHEREAEIIAQAGRKG
AVTIATNMAGRGTDIMLGGNADMLAKAQVGNDDSPEFAEAVQKIKPQVEAERAEVRSVGGLYIIGTERHESRRIDNQLRG
RSGRQGDPGESRFYLSLEDKLMRIFNGERIQKIMEMLNIPEDEPITAKMVTNAIEGAQRKVEGHNFDIRKNLMEYDSVMN
AQRNAIYGMRRKVLEGQEIERTTLDWLGDVVSNLLDTHIPEGGKKEEWSLEGLNNSLAQSFGFKIDFATMAVNTETVTDA
VKSGVKEVWERQKNSMGPFFEQVQKMILLQSIDHHWKNHLYVIDKLKEGISLRGYAQKDPLIEYKKEAFKAFETLNNTIK
SDAIEKVMRVQLVAQQNEQEVLESLRPEEADLDELDYSSPSEADIGHSIPETSEDAPKRKMTFQSGPRDDRPMNREERRR
MDKDTKGKR
>Mature_889_residues
MVTQILTKMFGTKHDREMKKIQPTVDRINALEPQMAALTDDQLKAKTPEFQERLKKGETVHDILPEAFAVCREASKRVLG
MRHYDVQLIGGYVLNRGNIAEMRTGEGKTLVATLPVYLNALTGRGVHVVTVNDYLVRRDAEHMGRLYGWLGLTTGIIVHG
LTDQQRKQMYACDITYCTNNELGFDYLRDNMKFDLNDYVQRPHYYAIVDECDSILVDEARTPLIISGPAESSTDKYYAVN
QIIPHLKRDVHFTMEEKSKTASLTDAGNAKVEELMGLSNLYDPQNIEILHHVYQGLKAHYLYRLDVEYMIKDGEIVIVDE
FTGRLMPGRRWSDGLHQAIEAKEGVEVKSENQTLATITFQNYFRMYEKLSGMTGTADTEAVEFKKIYNLEVNVIPTNRPI
QRKDQEDVVYKSEKAKFKAITADIKERMAKGQPILVGTESIEKSEALSAFLRKEGVKHEVLNAKHHEREAEIIAQAGRKG
AVTIATNMAGRGTDIMLGGNADMLAKAQVGNDDSPEFAEAVQKIKPQVEAERAEVRSVGGLYIIGTERHESRRIDNQLRG
RSGRQGDPGESRFYLSLEDKLMRIFNGERIQKIMEMLNIPEDEPITAKMVTNAIEGAQRKVEGHNFDIRKNLMEYDSVMN
AQRNAIYGMRRKVLEGQEIERTTLDWLGDVVSNLLDTHIPEGGKKEEWSLEGLNNSLAQSFGFKIDFATMAVNTETVTDA
VKSGVKEVWERQKNSMGPFFEQVQKMILLQSIDHHWKNHLYVIDKLKEGISLRGYAQKDPLIEYKKEAFKAFETLNNTIK
SDAIEKVMRVQLVAQQNEQEVLESLRPEEADLDELDYSSPSEADIGHSIPETSEDAPKRKMTFQSGPRDDRPMNREERRR
MDKDTKGKR

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=855, Percent_Identity=53.9181286549708, Blast_Score=890, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_BDEBA (Q6MR29)

Other databases:

- EMBL:   BX842646
- RefSeq:   NP_967275.1
- HSSP:   P28366
- ProteinModelPortal:   Q6MR29
- SMR:   Q6MR29
- GeneID:   2733273
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd0272
- NMPDR:   fig|264462.1.peg.245
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- PhylomeDB:   Q6MR29
- ProtClustDB:   PRK12904
- BioCyc:   BBAC264462:BD0272-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 101165; Mature: 101165

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTQILTKMFGTKHDREMKKIQPTVDRINALEPQMAALTDDQLKAKTPEFQERLKKGETV
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHCCCHHHHHHHHCCCHH
HDILPEAFAVCREASKRVLGMRHYDVQLIGGYVLNRGNIAEMRTGEGKTLVATLPVYLNA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCEEEEECCCCCEEEEEHHHHHHH
LTGRGVHVVTVNDYLVRRDAEHMGRLYGWLGLTTGIIVHGLTDQQRKQMYACDITYCTNN
HCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCHHHHCEEEEEEEEECCC
ELGFDYLRDNMKFDLNDYVQRPHYYAIVDECDSILVDEARTPLIISGPAESSTDKYYAVN
CCCHHHHHCCCCCCHHHHHCCCCEEEEHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEHH
QIIPHLKRDVHFTMEEKSKTASLTDAGNAKVEELMGLSNLYDPQNIEILHHVYQGLKAHY
HHHHHHHHCCEEEEHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHE
LYRLDVEYMIKDGEIVIVDEFTGRLMPGRRWSDGLHQAIEAKEGVEVKSENQTLATITFQ
EEEEEEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCEEEEEEHH
NYFRMYEKLSGMTGTADTEAVEFKKIYNLEVNVIPTNRPIQRKDQEDVVYKSEKAKFKAI
HHHHHHHHHCCCCCCCCCHHHHHHHEEEEEEEEEECCCCCCCCCCHHHHCCCCCHHHHHH
TADIKERMAKGQPILVGTESIEKSEALSAFLRKEGVKHEVLNAKHHEREAEIIAQAGRKG
HHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCC
AVTIATNMAGRGTDIMLGGNADMLAKAQVGNDDSPEFAEAVQKIKPQVEAERAEVRSVGG
EEEEEECCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCC
LYIIGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLEDKLMRIFNGERIQKIMEMLNIP
EEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHCCC
EDEPITAKMVTNAIEGAQRKVEGHNFDIRKNLMEYDSVMNAQRNAIYGMRRKVLEGQEIE
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RTTLDWLGDVVSNLLDTHIPEGGKKEEWSLEGLNNSLAQSFGFKIDFATMAVNTETVTDA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHCCCEEEEEEEEECHHHHHHH
VKSGVKEVWERQKNSMGPFFEQVQKMILLQSIDHHWKNHLYVIDKLKEGISLRGYAQKDP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCC
LIEYKKEAFKAFETLNNTIKSDAIEKVMRVQLVAQQNEQEVLESLRPEEADLDELDYSSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCC
SEADIGHSIPETSEDAPKRKMTFQSGPRDDRPMNREERRRMDKDTKGKR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVTQILTKMFGTKHDREMKKIQPTVDRINALEPQMAALTDDQLKAKTPEFQERLKKGETV
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHCCCHHHHHHHHCCCHH
HDILPEAFAVCREASKRVLGMRHYDVQLIGGYVLNRGNIAEMRTGEGKTLVATLPVYLNA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCEEEEECCCCCEEEEEHHHHHHH
LTGRGVHVVTVNDYLVRRDAEHMGRLYGWLGLTTGIIVHGLTDQQRKQMYACDITYCTNN
HCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCHHHHCEEEEEEEEECCC
ELGFDYLRDNMKFDLNDYVQRPHYYAIVDECDSILVDEARTPLIISGPAESSTDKYYAVN
CCCHHHHHCCCCCCHHHHHCCCCEEEEHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEHH
QIIPHLKRDVHFTMEEKSKTASLTDAGNAKVEELMGLSNLYDPQNIEILHHVYQGLKAHY
HHHHHHHHCCEEEEHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHE
LYRLDVEYMIKDGEIVIVDEFTGRLMPGRRWSDGLHQAIEAKEGVEVKSENQTLATITFQ
EEEEEEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCEEEEEEHH
NYFRMYEKLSGMTGTADTEAVEFKKIYNLEVNVIPTNRPIQRKDQEDVVYKSEKAKFKAI
HHHHHHHHHCCCCCCCCCHHHHHHHEEEEEEEEEECCCCCCCCCCHHHHCCCCCHHHHHH
TADIKERMAKGQPILVGTESIEKSEALSAFLRKEGVKHEVLNAKHHEREAEIIAQAGRKG
HHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCC
AVTIATNMAGRGTDIMLGGNADMLAKAQVGNDDSPEFAEAVQKIKPQVEAERAEVRSVGG
EEEEEECCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCC
LYIIGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLEDKLMRIFNGERIQKIMEMLNIP
EEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHCCC
EDEPITAKMVTNAIEGAQRKVEGHNFDIRKNLMEYDSVMNAQRNAIYGMRRKVLEGQEIE
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RTTLDWLGDVVSNLLDTHIPEGGKKEEWSLEGLNNSLAQSFGFKIDFATMAVNTETVTDA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHCCCEEEEEEEEECHHHHHHH
VKSGVKEVWERQKNSMGPFFEQVQKMILLQSIDHHWKNHLYVIDKLKEGISLRGYAQKDP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCC
LIEYKKEAFKAFETLNNTIKSDAIEKVMRVQLVAQQNEQEVLESLRPEEADLDELDYSSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCC
SEADIGHSIPETSEDAPKRKMTFQSGPRDDRPMNREERRRMDKDTKGKR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA