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The map label for this gene is pitA

Identifier: 41410139

GI number: 41410139

Start: 4501284

End: 4502552

Strand: Reverse

Name: pitA

Synonym: MAP4041c

Alternate gene names: 41410139

Gene position: 4502552-4501284 (Counterclockwise)

Preceding gene: 41410140

Following gene: 41410138

Centisome position: 93.22

GC content: 69.03

Gene sequence:

>1269_bases
TTGCCCCTACCACCAGAATCAGGCGCTGTGAACATCCAATTGTTCCTCTTGATCATTGTCGTAATCACGGCATTGGCTTT
CGATTTCACCAACGGCTTCCATGACACGGGCAACGCGATGGCCACCTCGATCGCCAGCGGTGCGCTCAAGCCCAAGACCG
CGGTCGCGCTCTCGGCGGTGCTGAATCTGGTGGGCGCCTTCATGTCCACCGCCGTCGCCGCCACCATCGCCAAGGGCCTG
ATCGACTCCAACATCGTCACGCTGGAGCTGGTGTTCGCCGGCCTGGTCGGCGGCGTGGTCTGGAACCTGCTGACCTGGCT
GCTGGGTATCCCGTCGAGCTCGTCGCACGCACTGATCGGCGGCATCGTCGGCGCCACGATCGCCGCCGTCGGCGCGCACG
GGGTGATCTGGAAGGGCGTGATCTCCAAGGCCATCATCCCGGCCATCGTCTCGGCGATCCTGGCCATCCTGGTCGGCGCG
GTCGCCACCTGGCTGGTCTACCGGATCACCCGCGGCGTCCCGAAGAAGCGCACCGAGGCCGGTTTCCGGCGCGGCCAGAT
CGGCTCGGCGTCGCTGGTGTCGCTGGCGCACGGCACCAACGACGCGCAGAAGACGATGGGCATCATCTTCCTGGCGCTGA
TCTCCTACGGCTCGGTCAGCAAGACCGCGGCCATGCCGCCGCTGTGGGTGATCGTCAGCTGCGCGCTGGCCATGGCGACC
GGCACCTACCTGGGCGGCTGGCGGATCATCCGCACCCTGGGCAAGGGCCTGGTGGAGATCCAGTCGCCGCAGGGCATGGC
GGCAGAGTCGTCGTCGGCCGCGGTGATCCTGCTGTCCGCCCACTTCGGCTACGCGCTGTCCACCACCCAGGTCTGCACGG
GCTCGGTGCTGGGCAGCGGGCTGGGCAAGCCCGGCGGCGAGGTCCGCTGGGGCGTGGCCGGCCGGATGGGGGTGGCCTGG
CTGGTCACCCTGCCGCTGGCCGGGCTGGTCGGCGCCGTCACCTACTGGATCGTGCACCTGATCGGCGGCTACCCCGGCGC
GATCATCGGCTTCGCGTTGCTGGTCGCGGTGTCGGCCACCATCTACCTGCGCTCGCGCAAGGTGAAGGTGGACCACCACA
ACGTCAACGCCGAGTGGAAGGGCGACCTGACCACCGGGCTGGAAGGCGCCGACGACCACTCCCCGCCCCCGGACGCCGGG
CCCCCGTTCGGCGGGCCGGGCGACCGGTACCAGTCCGACGACCCGACGCTCAAGGCGAGCGCGTCATGA

Upstream 100 bases:

>100_bases
CGAGGTGAACGGCAAGCGAAGCCCGGTTAACTGAGAGGTAACATCTGGCGACGACTCAAGGTACACCCGCGTTTCGGGTC
ATGCCGCATTCGACAATGGA

Downstream 100 bases:

>100_bases
GCCACCTCGGCGACTGGTTCAACTACCAGGCCAGCCTGAAGATCCTGCTGTTCGCCATGCTGGCCGGCGCGGCGCTGCCG
GGGCTGTTCGCCCTGGGCAT

Product: hypothetical protein

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MPLPPESGAVNIQLFLLIIVVITALAFDFTNGFHDTGNAMATSIASGALKPKTAVALSAVLNLVGAFMSTAVAATIAKGL
IDSNIVTLELVFAGLVGGVVWNLLTWLLGIPSSSSHALIGGIVGATIAAVGAHGVIWKGVISKAIIPAIVSAILAILVGA
VATWLVYRITRGVPKKRTEAGFRRGQIGSASLVSLAHGTNDAQKTMGIIFLALISYGSVSKTAAMPPLWVIVSCALAMAT
GTYLGGWRIIRTLGKGLVEIQSPQGMAAESSSAAVILLSAHFGYALSTTQVCTGSVLGSGLGKPGGEVRWGVAGRMGVAW
LVTLPLAGLVGAVTYWIVHLIGGYPGAIIGFALLVAVSATIYLRSRKVKVDHHNVNAEWKGDLTTGLEGADDHSPPPDAG
PPFGGPGDRYQSDDPTLKASAS

Sequences:

>Translated_422_residues
MPLPPESGAVNIQLFLLIIVVITALAFDFTNGFHDTGNAMATSIASGALKPKTAVALSAVLNLVGAFMSTAVAATIAKGL
IDSNIVTLELVFAGLVGGVVWNLLTWLLGIPSSSSHALIGGIVGATIAAVGAHGVIWKGVISKAIIPAIVSAILAILVGA
VATWLVYRITRGVPKKRTEAGFRRGQIGSASLVSLAHGTNDAQKTMGIIFLALISYGSVSKTAAMPPLWVIVSCALAMAT
GTYLGGWRIIRTLGKGLVEIQSPQGMAAESSSAAVILLSAHFGYALSTTQVCTGSVLGSGLGKPGGEVRWGVAGRMGVAW
LVTLPLAGLVGAVTYWIVHLIGGYPGAIIGFALLVAVSATIYLRSRKVKVDHHNVNAEWKGDLTTGLEGADDHSPPPDAG
PPFGGPGDRYQSDDPTLKASAS
>Mature_421_residues
PLPPESGAVNIQLFLLIIVVITALAFDFTNGFHDTGNAMATSIASGALKPKTAVALSAVLNLVGAFMSTAVAATIAKGLI
DSNIVTLELVFAGLVGGVVWNLLTWLLGIPSSSSHALIGGIVGATIAAVGAHGVIWKGVISKAIIPAIVSAILAILVGAV
ATWLVYRITRGVPKKRTEAGFRRGQIGSASLVSLAHGTNDAQKTMGIIFLALISYGSVSKTAAMPPLWVIVSCALAMATG
TYLGGWRIIRTLGKGLVEIQSPQGMAAESSSAAVILLSAHFGYALSTTQVCTGSVLGSGLGKPGGEVRWGVAGRMGVAWL
VTLPLAGLVGAVTYWIVHLIGGYPGAIIGFALLVAVSATIYLRSRKVKVDHHNVNAEWKGDLTTGLEGADDHSPPPDAGP
PFGGPGDRYQSDDPTLKASAS

Specific function: Low-affinity inorganic phosphate transport [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily [H]

Homologues:

Organism=Homo sapiens, GI5803173, Length=153, Percent_Identity=34.640522875817, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI31543630, Length=153, Percent_Identity=31.3725490196078, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789360, Length=217, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789907, Length=222, Percent_Identity=29.7297297297297, Blast_Score=88, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17539280, Length=161, Percent_Identity=31.6770186335404, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71981576, Length=171, Percent_Identity=29.8245614035088, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32566716, Length=178, Percent_Identity=28.6516853932584, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25146401, Length=172, Percent_Identity=28.4883720930233, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319773, Length=162, Percent_Identity=28.3950617283951, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356511, Length=209, Percent_Identity=27.7511961722488, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 43198; Mature: 43067

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPPESGAVNIQLFLLIIVVITALAFDFTNGFHDTGNAMATSIASGALKPKTAVALSAV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
LNLVGAFMSTAVAATIAKGLIDSNIVTLELVFAGLVGGVVWNLLTWLLGIPSSSSHALIG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
GIVGATIAAVGAHGVIWKGVISKAIIPAIVSAILAILVGAVATWLVYRITRGVPKKRTEA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GFRRGQIGSASLVSLAHGTNDAQKTMGIIFLALISYGSVSKTAAMPPLWVIVSCALAMAT
HHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHH
GTYLGGWRIIRTLGKGLVEIQSPQGMAAESSSAAVILLSAHFGYALSTTQVCTGSVLGSG
CCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCC
LGKPGGEVRWGVAGRMGVAWLVTLPLAGLVGAVTYWIVHLIGGYPGAIIGFALLVAVSAT
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IYLRSRKVKVDHHNVNAEWKGDLTTGLEGADDHSPPPDAGPPFGGPGDRYQSDDPTLKAS
HEEEECEEEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECC
AS
CC
>Mature Secondary Structure 
PLPPESGAVNIQLFLLIIVVITALAFDFTNGFHDTGNAMATSIASGALKPKTAVALSAV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
LNLVGAFMSTAVAATIAKGLIDSNIVTLELVFAGLVGGVVWNLLTWLLGIPSSSSHALIG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
GIVGATIAAVGAHGVIWKGVISKAIIPAIVSAILAILVGAVATWLVYRITRGVPKKRTEA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GFRRGQIGSASLVSLAHGTNDAQKTMGIIFLALISYGSVSKTAAMPPLWVIVSCALAMAT
HHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHH
GTYLGGWRIIRTLGKGLVEIQSPQGMAAESSSAAVILLSAHFGYALSTTQVCTGSVLGSG
CCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCC
LGKPGGEVRWGVAGRMGVAWLVTLPLAGLVGAVTYWIVHLIGGYPGAIIGFALLVAVSAT
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IYLRSRKVKVDHHNVNAEWKGDLTTGLEGADDHSPPPDAGPPFGGPGDRYQSDDPTLKAS
HEEEECEEEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECC
AS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]