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The map label for this gene is panE [C]

Identifier: 41410114

GI number: 41410114

Start: 4478365

End: 4479282

Strand: Reverse

Name: panE [C]

Synonym: MAP4016c

Alternate gene names: 41410114

Gene position: 4479282-4478365 (Counterclockwise)

Preceding gene: 41410115

Following gene: 41410110

Centisome position: 92.74

GC content: 72.88

Gene sequence:

>918_bases
ATGAAGATCGCGGTAATCGGTTGCGGCGCAATGGGTTCGATCTACGCCGCCAAGCTGGCCGCCGCGGGCGAGCAGGTGCT
GGCGGTCGACCGGCACCGGCCCAGCGTGGAGCGGATCAACCGGGACGGGCTGCGCGTCACCGGCCCCGGCTGCGACCAGG
TGGTGCCGCTGCGGGCCAGCACCGGCGCGGTCGACGAGACGATGGACCTGGTGGTGCTGGCGGTCAAGGCGGCCGACGTG
GAAGCCGCTGCGCGCCAAGCGCTTCCGATGCTGGGGCCGGATACCGCGGTGCTGACCATCCAGAACGGCCTGGGGTCGGC
GGAGACCGTCGCCGGCGTCGTCGGTACACAGCGGGTCGCGGTCGGGATCGCCAGCGGGTTCGGCGCGTCCCGGGTGGCGC
CGGGCCATGTCCACCACAACGCCATGCGGGCGATGCGCTTCGGCCCCTACTCGTCGCTGCCGCACGCGAGGGTGGAATCG
ATCGCCCGGACCTGGGCGCACGCCGGGTTCGACGCGGTCGCGGTCACCGACATCGCCGCGATGCAGTGGGAGAAGCTGAT
CTGCAACGTCGCCTACAGCGCGCCGTGCGCGCTGACCGGCATGACGGTCGGCCAGGTGATGGACGACGCCGAGATGGGTC
CGGTCAGCCGGGCGGCGGCCACCGAGGCGTGGTCGGTGGCGCGCGCGTCCGGTGTCGCGATCGCCGTCGCCGACGCGGTC
GAGCATGTCCGCGCGTTCGGGGCGCAGATGCCCGACGCGAAACCCTCGGCGCTGCTGGATCACGAGGCCCGCCGGGTCAG
CGAGATCGACGTCATCAACGGCGCGGTGCCGCGGCAGGGCGCGCGGGTCGGCGTCGACGCGCCGGTGAATGCGACGCTGA
CGGCCGTGGTCAAGTCCATCGAACGGCGGTGGCGCTGA

Upstream 100 bases:

>100_bases
TCTCGTCGGGCATGATCGCGCCGCCGGACGCCGCCGGGTTCGGGTTGGAGCAGAAACCCGGCCTGGCCGAACTGATCGCC
GAGCTGACGGGAGAACGCCG

Downstream 100 bases:

>100_bases
CCGGGCTCCGCTAGAACGGGCCGGGGCGGGTATACGGCACCGCGCCGGCGCGCACACCGGCTGAGCGCGGTCACCGCGCG
GCGACCCGGCCGCGCGAGCA

Product: hypothetical protein

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKIAVIGCGAMGSIYAAKLAAAGEQVLAVDRHRPSVERINRDGLRVTGPGCDQVVPLRASTGAVDETMDLVVLAVKAADV
EAAARQALPMLGPDTAVLTIQNGLGSAETVAGVVGTQRVAVGIASGFGASRVAPGHVHHNAMRAMRFGPYSSLPHARVES
IARTWAHAGFDAVAVTDIAAMQWEKLICNVAYSAPCALTGMTVGQVMDDAEMGPVSRAAATEAWSVARASGVAIAVADAV
EHVRAFGAQMPDAKPSALLDHEARRVSEIDVINGAVPRQGARVGVDAPVNATLTAVVKSIERRWR

Sequences:

>Translated_305_residues
MKIAVIGCGAMGSIYAAKLAAAGEQVLAVDRHRPSVERINRDGLRVTGPGCDQVVPLRASTGAVDETMDLVVLAVKAADV
EAAARQALPMLGPDTAVLTIQNGLGSAETVAGVVGTQRVAVGIASGFGASRVAPGHVHHNAMRAMRFGPYSSLPHARVES
IARTWAHAGFDAVAVTDIAAMQWEKLICNVAYSAPCALTGMTVGQVMDDAEMGPVSRAAATEAWSVARASGVAIAVADAV
EHVRAFGAQMPDAKPSALLDHEARRVSEIDVINGAVPRQGARVGVDAPVNATLTAVVKSIERRWR
>Mature_305_residues
MKIAVIGCGAMGSIYAAKLAAAGEQVLAVDRHRPSVERINRDGLRVTGPGCDQVVPLRASTGAVDETMDLVVLAVKAADV
EAAARQALPMLGPDTAVLTIQNGLGSAETVAGVVGTQRVAVGIASGFGASRVAPGHVHHNAMRAMRFGPYSSLPHARVES
IARTWAHAGFDAVAVTDIAAMQWEKLICNVAYSAPCALTGMTVGQVMDDAEMGPVSRAAATEAWSVARASGVAIAVADAV
EHVRAFGAQMPDAKPSALLDHEARRVSEIDVINGAVPRQGARVGVDAPVNATLTAVVKSIERRWR

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=315, Percent_Identity=26.3492063492064, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 31592; Mature: 31592

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVIGCGAMGSIYAAKLAAAGEQVLAVDRHRPSVERINRDGLRVTGPGCDQVVPLRAS
CEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCEEECCCCCCEEEECCC
TGAVDETMDLVVLAVKAADVEAAARQALPMLGPDTAVLTIQNGLGSAETVAGVVGTQRVA
CCCHHHHHHEEEEEHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHE
VGIASGFGASRVAPGHVHHNAMRAMRFGPYSSLPHARVESIARTWAHAGFDAVAVTDIAA
EEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
MQWEKLICNVAYSAPCALTGMTVGQVMDDAEMGPVSRAAATEAWSVARASGVAIAVADAV
HHHHHHHHHHHCCCCCHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHH
EHVRAFGAQMPDAKPSALLDHEARRVSEIDVINGAVPRQGARVGVDAPVNATLTAVVKSI
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHHH
ERRWR
HHHCC
>Mature Secondary Structure
MKIAVIGCGAMGSIYAAKLAAAGEQVLAVDRHRPSVERINRDGLRVTGPGCDQVVPLRAS
CEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCEEECCCCCCEEEECCC
TGAVDETMDLVVLAVKAADVEAAARQALPMLGPDTAVLTIQNGLGSAETVAGVVGTQRVA
CCCHHHHHHEEEEEHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHE
VGIASGFGASRVAPGHVHHNAMRAMRFGPYSSLPHARVESIARTWAHAGFDAVAVTDIAA
EEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
MQWEKLICNVAYSAPCALTGMTVGQVMDDAEMGPVSRAAATEAWSVARASGVAIAVADAV
HHHHHHHHHHHCCCCCHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHH
EHVRAFGAQMPDAKPSALLDHEARRVSEIDVINGAVPRQGARVGVDAPVNATLTAVVKSI
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHHH
ERRWR
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]