| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is hflB [C]
Identifier: 41410026
GI number: 41410026
Start: 4387333
End: 4389501
Strand: Reverse
Name: hflB [C]
Synonym: MAP3928c
Alternate gene names: 41410026
Gene position: 4389501-4387333 (Counterclockwise)
Preceding gene: 41410027
Following gene: 41410024
Centisome position: 90.88
GC content: 74.23
Gene sequence:
>2169_bases GTGACCGGTTCCGGCTCGGCGCGTCAACTCACGCTGACCGCCCGGCTGAACACCTCGGCCGTCGACTCCCGTCGCGGCGT CGTCCGCCTGCACCCGAGTGCCGTTGCGGCCCTTGGCATTCGGGAGTGGGACGCGGTGTCGCTGATCGGTTCGCGCACCA CCGCGGCGGTGGCCGGCCTGGCCGGCCCCGAAATACCCTCCGGCACCGTGTTGCTCGACGACGTGACGCTGTCCAACGCC GGCCTGCGCGACGGGACCGCCGTGGTGGTCAGCCCGGTCACCGTGTACGGCGCGCGGTCGGTGACCCTGTCCGGCTCGCC GCTGACCACCCGGTCGGTGTCACCGGTCACGTTGCGTCAGGCGCTGCTGGGCAAGGTGCTCACCGTCGGCGACGCGGTGT CGCTGCTGCCCCGCGACCTCGGGCCCGGCACCTCGACGTCCGAGGCGACCCGTGCGCTGGCCGCCGCGGTAGGCATCAGC TGGACCTCCGAGCTGCTGACCGTCACCGGCGTCGACCCGGACGGGCCGGTCAGCGTGCAGCCCAACTCGCTGGTCGGCTG GGGCGCCGGGGCGGCGCCCGCGGCGGCGTCGCGGGCCTCGGTCGAGGAAGCCCGCCCACAGACGGTGGTCGAGGAGCTCA AGGGCTGCCAGCCGCAGGCCGCCAAGCTGGTCGAATGGCTCAAGCTCGCGCTGGACGAGCCGCACCTGCTCAAGACCCTG GGCGCGGCCACCTTCCTGGGCGTGCTGGTGACCGGCCCGGCCGGGGTGGGCAAGGTGACGCTGGTGCGCGCGGTGTGCGG GGATCGCCGGCTGGTCACGCTGGACGGCCCGGAGGTCGGCGCGCTGGGCGCCGACGACCGGCTCAAGGCGGTGGCCTCGG CCGTGCAGACGGTCCGCGACGGCGGCGGCGTGCTGCTGATCACCGACGTCGACGCCCTGCTACCGGCCACCGCCGAGCCG GTGGCCTCGTTGATCCTCGCCGAGCTGCGCGGCGCGGTGGCCAGCGAGGGTGTCGCCCTGATCGCCACCTCGGCGCGCCC CGACCAGCTCGACGCCCGGCTGCGCGCGCCGGACCTGTGCGACCGGGAGCTGAGCCTGCCGCTGCCCGACGCCGCCACCC GCAAGGCCCTGCTGGAGTCGCTGCTGCGCAACGTGCCCACCGATGGCCTCGATTTGGATGAAATTGCTTCTCGCACACCG GGTTTCGTCGTCGCCGACCTGGCCGCGCTGATCCGCGAGGCGGCGCTGCGGGCGGCGTCGCGGGCCAGCTCCGACGGCCG TCCCCCCGCGCTGCACCAGGAGGACCTCACCGGCGCGCTGAGCGTGATCAGGCCGCTGTCCCGCTCGGCCGCCGAAGAGG TCAGCGTCGGGGACATCACCCTCGACGACGTCGGTGACATGGCGCAGGCCCGGCAGGCGCTCACCGAGGCGGTGTTGTGG CCGCTGCAGCATCCGGACACGTTCGCCCGGCTGGGTGTGCAGCCGCCGCGCGGGGTGCTGCTGTACGGGCCGCCCGGCTG CGGCAAGACCTTCGTGGTGCGCGCGCTGGCCAGCACCGGCCAGCTGTCGGTGCACGCCGTCAAGGGCTCCGAGCTGATGG ACAAGTGGGTGGGCAGCTCGGAAAAGGCGGTGCGCGAACTGTTTCGGCGGGCCCGGGATTCGGCGCCCGCGCTGATCTTT CTCGACGAGGTGGACGCGCTGGCGCCCCGGCGCGGGCAGAGCTTCGACTCCGGGGTGACCGACCGGGTGGTGGCCGCGCT GCTGACCGAACTGGACGGCGTCGACCCGCTGCGCGACGTCGTGGTGCTGGGCGCCACCAACCGGCCCGACCTCATCGACC CCGCGCTGCTGCGGCCGGGCCGGCTGGAGCGGCTGGTGTTCGTGGAGCCGCCCGACGCCGCGGCGCGGCGCGAAATCCTG CGCACCGCGGGCAAATCGATTCCGCTGAGCGCTGACGTCGACCTCGACGAGCTGGCCGCCGGCCTGGACGGCTACAGCGC CGCCGACTGCGTGGCGCTGCTGCGCGAGGCCGCGCTGACGGCCATGCGCCGGTCCATCGACGCCACCGACGTGACGGCCG CCGACCTCGCCGCGGCTCGCGAAAACGTCCGTCCCTCTTTGGATCCCGCGCAGGTCGCGTCGCTACGGGCGTTCGCCGAA GCTCCGTAG
Upstream 100 bases:
>100_bases CCAAGCAGCGCCGCGCCGCCCGGCGGGCGATCCGCCGGGCACAGCCCAACCGCCGGTCGGTGACGCGGCTGGGCCTGCGC AAGCCGGGCAGGCGCGTGCC
Downstream 100 bases:
>100_bases CACGGCCCGGGCCGACGCGGCCACGTCGGTTTCCAGCCAGGACGGCATCGGGTCGTCGTGCGCGTGACGGCGCACCACGG CATACGGCAGGTCGGCGACG
Product: hypothetical protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 722; Mature: 721
Protein sequence:
>722_residues MTGSGSARQLTLTARLNTSAVDSRRGVVRLHPSAVAALGIREWDAVSLIGSRTTAAVAGLAGPEIPSGTVLLDDVTLSNA GLRDGTAVVVSPVTVYGARSVTLSGSPLTTRSVSPVTLRQALLGKVLTVGDAVSLLPRDLGPGTSTSEATRALAAAVGIS WTSELLTVTGVDPDGPVSVQPNSLVGWGAGAAPAAASRASVEEARPQTVVEELKGCQPQAAKLVEWLKLALDEPHLLKTL GAATFLGVLVTGPAGVGKVTLVRAVCGDRRLVTLDGPEVGALGADDRLKAVASAVQTVRDGGGVLLITDVDALLPATAEP VASLILAELRGAVASEGVALIATSARPDQLDARLRAPDLCDRELSLPLPDAATRKALLESLLRNVPTDGLDLDEIASRTP GFVVADLAALIREAALRAASRASSDGRPPALHQEDLTGALSVIRPLSRSAAEEVSVGDITLDDVGDMAQARQALTEAVLW PLQHPDTFARLGVQPPRGVLLYGPPGCGKTFVVRALASTGQLSVHAVKGSELMDKWVGSSEKAVRELFRRARDSAPALIF LDEVDALAPRRGQSFDSGVTDRVVAALLTELDGVDPLRDVVVLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARREIL RTAGKSIPLSADVDLDELAAGLDGYSAADCVALLREAALTAMRRSIDATDVTAADLAAARENVRPSLDPAQVASLRAFAE AP
Sequences:
>Translated_722_residues MTGSGSARQLTLTARLNTSAVDSRRGVVRLHPSAVAALGIREWDAVSLIGSRTTAAVAGLAGPEIPSGTVLLDDVTLSNA GLRDGTAVVVSPVTVYGARSVTLSGSPLTTRSVSPVTLRQALLGKVLTVGDAVSLLPRDLGPGTSTSEATRALAAAVGIS WTSELLTVTGVDPDGPVSVQPNSLVGWGAGAAPAAASRASVEEARPQTVVEELKGCQPQAAKLVEWLKLALDEPHLLKTL GAATFLGVLVTGPAGVGKVTLVRAVCGDRRLVTLDGPEVGALGADDRLKAVASAVQTVRDGGGVLLITDVDALLPATAEP VASLILAELRGAVASEGVALIATSARPDQLDARLRAPDLCDRELSLPLPDAATRKALLESLLRNVPTDGLDLDEIASRTP GFVVADLAALIREAALRAASRASSDGRPPALHQEDLTGALSVIRPLSRSAAEEVSVGDITLDDVGDMAQARQALTEAVLW PLQHPDTFARLGVQPPRGVLLYGPPGCGKTFVVRALASTGQLSVHAVKGSELMDKWVGSSEKAVRELFRRARDSAPALIF LDEVDALAPRRGQSFDSGVTDRVVAALLTELDGVDPLRDVVVLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARREIL RTAGKSIPLSADVDLDELAAGLDGYSAADCVALLREAALTAMRRSIDATDVTAADLAAARENVRPSLDPAQVASLRAFAE AP >Mature_721_residues TGSGSARQLTLTARLNTSAVDSRRGVVRLHPSAVAALGIREWDAVSLIGSRTTAAVAGLAGPEIPSGTVLLDDVTLSNAG LRDGTAVVVSPVTVYGARSVTLSGSPLTTRSVSPVTLRQALLGKVLTVGDAVSLLPRDLGPGTSTSEATRALAAAVGISW TSELLTVTGVDPDGPVSVQPNSLVGWGAGAAPAAASRASVEEARPQTVVEELKGCQPQAAKLVEWLKLALDEPHLLKTLG AATFLGVLVTGPAGVGKVTLVRAVCGDRRLVTLDGPEVGALGADDRLKAVASAVQTVRDGGGVLLITDVDALLPATAEPV ASLILAELRGAVASEGVALIATSARPDQLDARLRAPDLCDRELSLPLPDAATRKALLESLLRNVPTDGLDLDEIASRTPG FVVADLAALIREAALRAASRASSDGRPPALHQEDLTGALSVIRPLSRSAAEEVSVGDITLDDVGDMAQARQALTEAVLWP LQHPDTFARLGVQPPRGVLLYGPPGCGKTFVVRALASTGQLSVHAVKGSELMDKWVGSSEKAVRELFRRARDSAPALIFL DEVDALAPRRGQSFDSGVTDRVVAALLTELDGVDPLRDVVVLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARREILR TAGKSIPLSADVDLDELAAGLDGYSAADCVALLREAALTAMRRSIDATDVTAADLAAARENVRPSLDPAQVASLRAFAEA P
Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving
COG id: COG0464
COG function: function code O; ATPases of the AAA+ class
Gene ontology:
Cell location: Integral Membrane Protein. Inner Membrane [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]
Homologues:
Organism=Homo sapiens, GI157671927, Length=535, Percent_Identity=40.3738317757009, Blast_Score=352, Evalue=6e-97, Organism=Homo sapiens, GI6005942, Length=543, Percent_Identity=33.7016574585635, Blast_Score=298, Evalue=2e-80, Organism=Homo sapiens, GI45643123, Length=536, Percent_Identity=36.9402985074627, Blast_Score=289, Evalue=8e-78, Organism=Homo sapiens, GI45643125, Length=536, Percent_Identity=36.9402985074627, Blast_Score=289, Evalue=8e-78, Organism=Homo sapiens, GI229577436, Length=508, Percent_Identity=36.4173228346457, Blast_Score=286, Evalue=4e-77, Organism=Homo sapiens, GI4505725, Length=468, Percent_Identity=36.3247863247863, Blast_Score=247, Evalue=3e-65, Organism=Homo sapiens, GI194018488, Length=510, Percent_Identity=33.7254901960784, Blast_Score=212, Evalue=1e-54, Organism=Homo sapiens, GI24497618, Length=244, Percent_Identity=42.2131147540984, Blast_Score=191, Evalue=2e-48, Organism=Homo sapiens, GI24430151, Length=246, Percent_Identity=40.2439024390244, Blast_Score=190, Evalue=4e-48, Organism=Homo sapiens, GI153792536, Length=281, Percent_Identity=39.1459074733096, Blast_Score=190, Evalue=4e-48, Organism=Homo sapiens, GI24430155, Length=251, Percent_Identity=39.8406374501992, Blast_Score=186, Evalue=5e-47, Organism=Homo sapiens, GI195539395, Length=273, Percent_Identity=37.3626373626374, Blast_Score=186, Evalue=5e-47, Organism=Homo sapiens, GI5729991, Length=251, Percent_Identity=39.8406374501992, Blast_Score=186, Evalue=6e-47, Organism=Homo sapiens, GI21361144, Length=236, Percent_Identity=39.8305084745763, Blast_Score=186, Evalue=7e-47, Organism=Homo sapiens, GI89064750, Length=251, Percent_Identity=39.8406374501992, Blast_Score=186, Evalue=8e-47, Organism=Homo sapiens, GI5901990, Length=238, Percent_Identity=42.0168067226891, Blast_Score=179, Evalue=1e-44, Organism=Homo sapiens, GI4506209, Length=231, Percent_Identity=41.1255411255411, Blast_Score=177, Evalue=3e-44, Organism=Homo sapiens, GI24497435, Length=248, Percent_Identity=37.9032258064516, Blast_Score=176, Evalue=9e-44, Organism=Homo sapiens, GI14149767, Length=237, Percent_Identity=41.3502109704641, Blast_Score=170, Evalue=5e-42, Organism=Homo sapiens, GI62177112, Length=237, Percent_Identity=41.3502109704641, Blast_Score=170, Evalue=5e-42, Organism=Homo sapiens, GI300192933, Length=271, Percent_Identity=35.0553505535055, Blast_Score=167, Evalue=3e-41, Organism=Homo sapiens, GI21327685, Length=256, Percent_Identity=35.9375, Blast_Score=165, Evalue=1e-40, Organism=Homo sapiens, GI7657689, Length=256, Percent_Identity=35.9375, Blast_Score=165, Evalue=2e-40, Organism=Homo sapiens, GI156564401, Length=256, Percent_Identity=39.453125, Blast_Score=165, Evalue=2e-40, Organism=Homo sapiens, GI310125280, Length=230, Percent_Identity=41.304347826087, Blast_Score=164, Evalue=2e-40, Organism=Homo sapiens, GI310125282, Length=230, Percent_Identity=41.304347826087, Blast_Score=163, Evalue=5e-40, Organism=Homo sapiens, GI7019569, Length=278, Percent_Identity=35.6115107913669, Blast_Score=157, Evalue=3e-38, Organism=Homo sapiens, GI4507173, Length=247, Percent_Identity=36.4372469635627, Blast_Score=157, Evalue=3e-38, Organism=Homo sapiens, GI31742536, Length=265, Percent_Identity=34.3396226415094, Blast_Score=152, Evalue=1e-36, Organism=Homo sapiens, GI112789543, Length=265, Percent_Identity=34.3396226415094, Blast_Score=152, Evalue=1e-36, Organism=Homo sapiens, GI17865802, Length=263, Percent_Identity=33.8403041825095, Blast_Score=146, Evalue=6e-35, Organism=Homo sapiens, GI226371754, Length=268, Percent_Identity=32.8358208955224, Blast_Score=139, Evalue=1e-32, Organism=Homo sapiens, GI31377644, Length=267, Percent_Identity=33.7078651685393, Blast_Score=137, Evalue=3e-32, Organism=Homo sapiens, GI40806170, Length=265, Percent_Identity=34.3396226415094, Blast_Score=136, Evalue=9e-32, Organism=Homo sapiens, GI11875211, Length=265, Percent_Identity=34.3396226415094, Blast_Score=135, Evalue=9e-32, Organism=Homo sapiens, GI64084766, Length=263, Percent_Identity=28.8973384030418, Blast_Score=100, Evalue=5e-21, Organism=Homo sapiens, GI40806173, Length=138, Percent_Identity=35.5072463768116, Blast_Score=95, Evalue=3e-19, Organism=Homo sapiens, GI116292174, Length=242, Percent_Identity=28.5123966942149, Blast_Score=78, Evalue=3e-14, Organism=Escherichia coli, GI1789568, Length=248, Percent_Identity=37.9032258064516, Blast_Score=174, Evalue=1e-44, Organism=Caenorhabditis elegans, GI17531535, Length=693, Percent_Identity=31.3131313131313, Blast_Score=307, Evalue=1e-83, Organism=Caenorhabditis elegans, GI17532375, Length=694, Percent_Identity=31.1239193083574, Blast_Score=306, Evalue=3e-83, Organism=Caenorhabditis elegans, GI17537217, Length=573, Percent_Identity=33.1588132635253, Blast_Score=265, Evalue=4e-71, Organism=Caenorhabditis elegans, GI17508053, Length=456, Percent_Identity=38.8157894736842, Blast_Score=262, Evalue=5e-70, Organism=Caenorhabditis elegans, GI25153574, Length=461, Percent_Identity=31.6702819956616, Blast_Score=210, Evalue=2e-54, Organism=Caenorhabditis elegans, GI193209502, Length=225, Percent_Identity=43.1111111111111, Blast_Score=196, Evalue=3e-50, Organism=Caenorhabditis elegans, GI17562804, Length=463, Percent_Identity=28.7257019438445, Blast_Score=194, Evalue=1e-49, Organism=Caenorhabditis elegans, GI71987372, Length=297, Percent_Identity=37.7104377104377, Blast_Score=192, Evalue=5e-49, Organism=Caenorhabditis elegans, GI71987364, Length=297, Percent_Identity=37.7104377104377, Blast_Score=192, Evalue=5e-49, Organism=Caenorhabditis elegans, GI17563250, Length=246, Percent_Identity=40.650406504065, Blast_Score=189, Evalue=5e-48, Organism=Caenorhabditis elegans, GI17508701, Length=239, Percent_Identity=40.1673640167364, Blast_Score=188, Evalue=7e-48, Organism=Caenorhabditis elegans, GI17554784, Length=315, Percent_Identity=36.5079365079365, Blast_Score=187, Evalue=3e-47, Organism=Caenorhabditis elegans, GI17563248, Length=229, Percent_Identity=43.6681222707424, Blast_Score=179, Evalue=5e-45, Organism=Caenorhabditis elegans, GI17554786, Length=238, Percent_Identity=38.2352941176471, Blast_Score=176, Evalue=5e-44, Organism=Caenorhabditis elegans, GI25144281, Length=299, Percent_Identity=35.1170568561873, Blast_Score=175, Evalue=9e-44, Organism=Caenorhabditis elegans, GI25144278, Length=299, Percent_Identity=35.1170568561873, Blast_Score=174, Evalue=1e-43, Organism=Caenorhabditis elegans, GI193206116, Length=236, Percent_Identity=41.5254237288136, Blast_Score=173, Evalue=2e-43, Organism=Caenorhabditis elegans, GI193206114, Length=236, Percent_Identity=41.5254237288136, Blast_Score=173, Evalue=3e-43, Organism=Caenorhabditis elegans, GI133931034, Length=236, Percent_Identity=41.5254237288136, Blast_Score=173, Evalue=3e-43, Organism=Caenorhabditis elegans, GI17508421, Length=252, Percent_Identity=39.2857142857143, Blast_Score=162, Evalue=5e-40, Organism=Caenorhabditis elegans, GI32563584, Length=254, Percent_Identity=38.9763779527559, Blast_Score=162, Evalue=8e-40, Organism=Caenorhabditis elegans, GI25146157, Length=278, Percent_Identity=34.5323741007194, Blast_Score=157, Evalue=2e-38, Organism=Caenorhabditis elegans, GI17505546, Length=226, Percent_Identity=34.5132743362832, Blast_Score=156, Evalue=3e-38, Organism=Caenorhabditis elegans, GI86561515, Length=262, Percent_Identity=33.969465648855, Blast_Score=156, Evalue=4e-38, Organism=Caenorhabditis elegans, GI17554264, Length=237, Percent_Identity=37.9746835443038, Blast_Score=152, Evalue=7e-37, Organism=Caenorhabditis elegans, GI133901662, Length=225, Percent_Identity=37.3333333333333, Blast_Score=142, Evalue=6e-34, Organism=Caenorhabditis elegans, GI133901658, Length=225, Percent_Identity=37.3333333333333, Blast_Score=142, Evalue=8e-34, Organism=Caenorhabditis elegans, GI17560432, Length=270, Percent_Identity=36.2962962962963, Blast_Score=140, Evalue=3e-33, Organism=Caenorhabditis elegans, GI115534323, Length=276, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=2e-32, Organism=Caenorhabditis elegans, GI71994521, Length=244, Percent_Identity=34.8360655737705, Blast_Score=127, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17541224, Length=219, Percent_Identity=34.703196347032, Blast_Score=124, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17541226, Length=219, Percent_Identity=34.703196347032, Blast_Score=124, Evalue=2e-28, Organism=Saccharomyces cerevisiae, GI6320077, Length=597, Percent_Identity=33.1658291457286, Blast_Score=306, Evalue=9e-84, Organism=Saccharomyces cerevisiae, GI6323429, Length=529, Percent_Identity=35.1606805293006, Blast_Score=304, Evalue=3e-83, Organism=Saccharomyces cerevisiae, GI6322994, Length=576, Percent_Identity=31.5972222222222, Blast_Score=273, Evalue=1e-73, Organism=Saccharomyces cerevisiae, GI6324000, Length=346, Percent_Identity=35.2601156069364, Blast_Score=200, Evalue=8e-52, Organism=Saccharomyces cerevisiae, GI6322651, Length=366, Percent_Identity=33.0601092896175, Blast_Score=199, Evalue=9e-52, Organism=Saccharomyces cerevisiae, GI6321390, Length=294, Percent_Identity=35.7142857142857, Blast_Score=188, Evalue=3e-48, Organism=Saccharomyces cerevisiae, GI6320602, Length=303, Percent_Identity=39.6039603960396, Blast_Score=187, Evalue=4e-48, Organism=Saccharomyces cerevisiae, GI6320197, Length=273, Percent_Identity=36.6300366300366, Blast_Score=185, Evalue=3e-47, Organism=Saccharomyces cerevisiae, GI6321709, Length=236, Percent_Identity=41.1016949152542, Blast_Score=184, Evalue=5e-47, Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=39.0243902439024, Blast_Score=182, Evalue=1e-46, Organism=Saccharomyces cerevisiae, GI6322704, Length=231, Percent_Identity=40.2597402597403, Blast_Score=169, Evalue=2e-42, Organism=Saccharomyces cerevisiae, GI6323736, Length=271, Percent_Identity=36.1623616236162, Blast_Score=166, Evalue=2e-41, Organism=Saccharomyces cerevisiae, GI6325281, Length=248, Percent_Identity=36.6935483870968, Blast_Score=160, Evalue=1e-39, Organism=Saccharomyces cerevisiae, GI6324691, Length=227, Percent_Identity=36.5638766519824, Blast_Score=154, Evalue=4e-38, Organism=Saccharomyces cerevisiae, GI6325431, Length=243, Percent_Identity=36.6255144032922, Blast_Score=154, Evalue=5e-38, Organism=Saccharomyces cerevisiae, GI6319554, Length=234, Percent_Identity=37.1794871794872, Blast_Score=153, Evalue=1e-37, Organism=Saccharomyces cerevisiae, GI6320854, Length=238, Percent_Identity=37.3949579831933, Blast_Score=150, Evalue=5e-37, Organism=Saccharomyces cerevisiae, GI6321465, Length=231, Percent_Identity=38.5281385281385, Blast_Score=144, Evalue=4e-35, Organism=Saccharomyces cerevisiae, GI6325183, Length=270, Percent_Identity=32.5925925925926, Blast_Score=129, Evalue=2e-30, Organism=Saccharomyces cerevisiae, GI6320887, Length=280, Percent_Identity=31.4285714285714, Blast_Score=125, Evalue=2e-29, Organism=Saccharomyces cerevisiae, GI6320583, Length=171, Percent_Identity=29.2397660818713, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI161076486, Length=703, Percent_Identity=30.4409672830725, Blast_Score=306, Evalue=4e-83, Organism=Drosophila melanogaster, GI17137560, Length=703, Percent_Identity=30.4409672830725, Blast_Score=305, Evalue=5e-83, Organism=Drosophila melanogaster, GI19921202, Length=492, Percent_Identity=37.8048780487805, Blast_Score=303, Evalue=2e-82, Organism=Drosophila melanogaster, GI161076488, Length=519, Percent_Identity=34.4894026974952, Blast_Score=303, Evalue=3e-82, Organism=Drosophila melanogaster, GI24660075, Length=281, Percent_Identity=44.4839857651246, Blast_Score=239, Evalue=7e-63, Organism=Drosophila melanogaster, GI281365776, Length=281, Percent_Identity=44.4839857651246, Blast_Score=239, Evalue=7e-63, Organism=Drosophila melanogaster, GI45552965, Length=281, Percent_Identity=44.4839857651246, Blast_Score=238, Evalue=9e-63, Organism=Drosophila melanogaster, GI24656825, Length=499, Percent_Identity=32.4649298597194, Blast_Score=225, Evalue=1e-58, Organism=Drosophila melanogaster, GI24656820, Length=434, Percent_Identity=34.331797235023, Blast_Score=222, Evalue=9e-58, Organism=Drosophila melanogaster, GI21355121, Length=424, Percent_Identity=34.1981132075472, Blast_Score=212, Evalue=6e-55, Organism=Drosophila melanogaster, GI18860063, Length=314, Percent_Identity=36.9426751592357, Blast_Score=197, Evalue=3e-50, Organism=Drosophila melanogaster, GI281363136, Length=306, Percent_Identity=39.5424836601307, Blast_Score=193, Evalue=3e-49, Organism=Drosophila melanogaster, GI78707192, Length=306, Percent_Identity=39.5424836601307, Blast_Score=193, Evalue=3e-49, Organism=Drosophila melanogaster, GI24652279, Length=198, Percent_Identity=44.9494949494949, Blast_Score=190, Evalue=4e-48, Organism=Drosophila melanogaster, GI281361487, Length=253, Percent_Identity=38.3399209486166, Blast_Score=187, Evalue=2e-47, Organism=Drosophila melanogaster, GI24649446, Length=246, Percent_Identity=40.2439024390244, Blast_Score=187, Evalue=2e-47, Organism=Drosophila melanogaster, GI17738151, Length=239, Percent_Identity=40.1673640167364, Blast_Score=187, Evalue=3e-47, Organism=Drosophila melanogaster, GI24640100, Length=242, Percent_Identity=40.0826446280992, Blast_Score=182, Evalue=1e-45, Organism=Drosophila melanogaster, GI19920408, Length=247, Percent_Identity=38.0566801619433, Blast_Score=182, Evalue=1e-45, Organism=Drosophila melanogaster, GI24651451, Length=268, Percent_Identity=36.9402985074627, Blast_Score=181, Evalue=2e-45, Organism=Drosophila melanogaster, GI24663015, Length=246, Percent_Identity=39.0243902439024, Blast_Score=179, Evalue=4e-45, Organism=Drosophila melanogaster, GI17137738, Length=231, Percent_Identity=41.991341991342, Blast_Score=179, Evalue=7e-45, Organism=Drosophila melanogaster, GI24658770, Length=253, Percent_Identity=40.3162055335968, Blast_Score=169, Evalue=7e-42, Organism=Drosophila melanogaster, GI24639391, Length=253, Percent_Identity=35.5731225296443, Blast_Score=156, Evalue=5e-38, Organism=Drosophila melanogaster, GI24644145, Length=233, Percent_Identity=39.0557939914163, Blast_Score=154, Evalue=1e-37, Organism=Drosophila melanogaster, GI28573010, Length=255, Percent_Identity=37.2549019607843, Blast_Score=152, Evalue=7e-37, Organism=Drosophila melanogaster, GI28574878, Length=253, Percent_Identity=35.1778656126482, Blast_Score=152, Evalue=1e-36, Organism=Drosophila melanogaster, GI24665814, Length=252, Percent_Identity=35.3174603174603, Blast_Score=151, Evalue=1e-36, Organism=Drosophila melanogaster, GI17864540, Length=218, Percent_Identity=40.3669724770642, Blast_Score=150, Evalue=3e-36, Organism=Drosophila melanogaster, GI18859657, Length=236, Percent_Identity=35.5932203389831, Blast_Score=147, Evalue=4e-35, Organism=Drosophila melanogaster, GI24581396, Length=230, Percent_Identity=38.695652173913, Blast_Score=145, Evalue=1e-34, Organism=Drosophila melanogaster, GI281360146, Length=233, Percent_Identity=37.3390557939914, Blast_Score=142, Evalue=6e-34, Organism=Drosophila melanogaster, GI281360138, Length=233, Percent_Identity=37.3390557939914, Blast_Score=142, Evalue=6e-34, Organism=Drosophila melanogaster, GI281360142, Length=233, Percent_Identity=37.3390557939914, Blast_Score=142, Evalue=7e-34, Organism=Drosophila melanogaster, GI21357333, Length=233, Percent_Identity=37.3390557939914, Blast_Score=142, Evalue=7e-34, Organism=Drosophila melanogaster, GI281360144, Length=233, Percent_Identity=37.3390557939914, Blast_Score=142, Evalue=7e-34, Organism=Drosophila melanogaster, GI281360140, Length=233, Percent_Identity=37.3390557939914, Blast_Score=142, Evalue=7e-34, Organism=Drosophila melanogaster, GI281360136, Length=233, Percent_Identity=37.3390557939914, Blast_Score=142, Evalue=8e-34, Organism=Drosophila melanogaster, GI24644411, Length=233, Percent_Identity=37.3390557939914, Blast_Score=142, Evalue=8e-34, Organism=Drosophila melanogaster, GI20129423, Length=256, Percent_Identity=34.375, Blast_Score=141, Evalue=1e-33, Organism=Drosophila melanogaster, GI20129529, Length=232, Percent_Identity=35.3448275862069, Blast_Score=132, Evalue=7e-31, Organism=Drosophila melanogaster, GI24639486, Length=229, Percent_Identity=36.6812227074236, Blast_Score=131, Evalue=2e-30, Organism=Drosophila melanogaster, GI28571849, Length=253, Percent_Identity=38.3399209486166, Blast_Score=126, Evalue=6e-29, Organism=Drosophila melanogaster, GI28571847, Length=253, Percent_Identity=38.3399209486166, Blast_Score=126, Evalue=6e-29, Organism=Drosophila melanogaster, GI45554047, Length=167, Percent_Identity=35.9281437125749, Blast_Score=117, Evalue=2e-26, Organism=Drosophila melanogaster, GI20129417, Length=177, Percent_Identity=29.9435028248588, Blast_Score=74, Evalue=5e-13, Organism=Drosophila melanogaster, GI24583262, Length=177, Percent_Identity=29.9435028248588, Blast_Score=74, Evalue=5e-13, Organism=Drosophila melanogaster, GI28573181, Length=161, Percent_Identity=32.2981366459627, Blast_Score=66, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR009010 - InterPro: IPR003593 - InterPro: IPR005938 - InterPro: IPR003959 - InterPro: IPR003960 - InterPro: IPR003338 - InterPro: IPR004201 - InterPro: IPR015415 [H]
Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]
EC number: 3.4.24.- [C]
Molecular weight: Translated: 74674; Mature: 74543
Theoretical pI: Translated: 4.83; Mature: 4.83
Prosite motif: PS00674 AAA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 0.6 %Met (Translated Protein) 1.2 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 0.4 %Met (Mature Protein) 1.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTGSGSARQLTLTARLNTSAVDSRRGVVRLHPSAVAALGIREWDAVSLIGSRTTAAVAGL CCCCCCCEEEEEEEECCCHHHHCCCCEEEECCHHHHHHCCCCCCHHHHHCCCHHHHHHHC AGPEIPSGTVLLDDVTLSNAGLRDGTAVVVSPVTVYGARSVTLSGSPLTTRSVSPVTLRQ CCCCCCCCCEEEEEEEECCCCCCCCCEEEEECEEEECCEEEEECCCCCCCCCCCHHHHHH ALLGKVLTVGDAVSLLPRDLGPGTSTSEATRALAAAVGISWTSELLTVTGVDPDGPVSVQ HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEC PNSLVGWGAGAAPAAASRASVEEARPQTVVEELKGCQPQAAKLVEWLKLALDEPHLLKTL CCCEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH GAATFLGVLVTGPAGVGKVTLVRAVCGDRRLVTLDGPEVGALGADDRLKAVASAVQTVRD HHHHHHHHHEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHC GGGVLLITDVDALLPATAEPVASLILAELRGAVASEGVALIATSARPDQLDARLRAPDLC CCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCCCCC DRELSLPLPDAATRKALLESLLRNVPTDGLDLDEIASRTPGFVVADLAALIREAALRAAS CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHH RASSDGRPPALHQEDLTGALSVIRPLSRSAAEEVSVGDITLDDVGDMAQARQALTEAVLW HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHC PLQHPDTFARLGVQPPRGVLLYGPPGCGKTFVVRALASTGQLSVHAVKGSELMDKWVGSS CCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCC EKAVRELFRRARDSAPALIFLDEVDALAPRRGQSFDSGVTDRVVAALLTELDGVDPLRDV HHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHE VVLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARREILRTAGKSIPLSADVDLDELAA EEECCCCCCCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHH GLDGYSAADCVALLREAALTAMRRSIDATDVTAADLAAARENVRPSLDPAQVASLRAFAE CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHC AP CC >Mature Secondary Structure TGSGSARQLTLTARLNTSAVDSRRGVVRLHPSAVAALGIREWDAVSLIGSRTTAAVAGL CCCCCCEEEEEEEECCCHHHHCCCCEEEECCHHHHHHCCCCCCHHHHHCCCHHHHHHHC AGPEIPSGTVLLDDVTLSNAGLRDGTAVVVSPVTVYGARSVTLSGSPLTTRSVSPVTLRQ CCCCCCCCCEEEEEEEECCCCCCCCCEEEEECEEEECCEEEEECCCCCCCCCCCHHHHHH ALLGKVLTVGDAVSLLPRDLGPGTSTSEATRALAAAVGISWTSELLTVTGVDPDGPVSVQ HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEC PNSLVGWGAGAAPAAASRASVEEARPQTVVEELKGCQPQAAKLVEWLKLALDEPHLLKTL CCCEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH GAATFLGVLVTGPAGVGKVTLVRAVCGDRRLVTLDGPEVGALGADDRLKAVASAVQTVRD HHHHHHHHHEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHC GGGVLLITDVDALLPATAEPVASLILAELRGAVASEGVALIATSARPDQLDARLRAPDLC CCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCCCCC DRELSLPLPDAATRKALLESLLRNVPTDGLDLDEIASRTPGFVVADLAALIREAALRAAS CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHH RASSDGRPPALHQEDLTGALSVIRPLSRSAAEEVSVGDITLDDVGDMAQARQALTEAVLW HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHC PLQHPDTFARLGVQPPRGVLLYGPPGCGKTFVVRALASTGQLSVHAVKGSELMDKWVGSS CCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCC EKAVRELFRRARDSAPALIFLDEVDALAPRRGQSFDSGVTDRVVAALLTELDGVDPLRDV HHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHE VVLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARREILRTAGKSIPLSADVDLDELAA EEECCCCCCCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHH GLDGYSAADCVALLREAALTAMRRSIDATDVTAADLAAARENVRPSLDPAQVASLRAFAE CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHC AP CC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9389475 [H]