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The map label for this gene is mrp

Identifier: 41408651

GI number: 41408651

Start: 2871210

End: 2872370

Strand: Direct

Name: mrp

Synonym: MAP2553

Alternate gene names: 41408651

Gene position: 2871210-2872370 (Clockwise)

Preceding gene: 41408650

Following gene: 41408656

Centisome position: 59.45

GC content: 72.01

Gene sequence:

>1161_bases
GTGATGTCCCGCCATGACTCCTCCGACTCAGCAGCCGACCTGAGCGCCGCCGTCCGCGCCGCCCTGGGCAAGGTGATCGA
CCCCGAACTGCGGCGTCCGATCACCGAACTCGGGATGGTCAAGAGCATCGACACCGAGCCCGACGGCGCGGTGCATGTCG
CGATCTACCTGACCACGGCCGCGTGCCCGAAGAAGACCGAGATCAGCGACCGGGTCACCCGGGCGGTCGCCGACGTCCCG
GGCACCGGCGCGGTCAAGGTCACCCTGGACGTGATGAGCGACGAGCAGCGCACCGAGCTGCGCAAGCAGCTGCGCGGCGA
TGCCCGCGAGCCGGTTATCCCGTTCGCGCAACCGAATTCGCTGACCCGGGTCTACGCGGTCGCGTCCGGCAAGGGCGGGG
TGGGAAAGTCCACCGTCACCGTCAACCTGGCGGCGGCGATGGCCGCCCGCGGCCTGTCGGTCGGCGTGCTGGACGCCGAC
ATCCACGGCCATTCCATCCCGCGGATGATGGGCACCACCGACCGGCCCACCCAGGTCGAGTCGATGATCCTGCCGCCCAT
CGCCCACGACGTGCGGGTCATCTCGATCGCCCAGTTCACCCAGGGAAACACCCCGGTCGTGTGGCGCGGCCCGATGCTGC
ACCGGGCGCTGCAGCAGTTCCTGGCCGACGTCTACTGGGGCGACCTGGACGTGCTGCTGCTCGACCTGCCGCCGGGCACC
GGTGACATCGCCATTTCGGTGGCCCAGCTGATTCCCAACGCCGAGATCCTGGTGGTGACGACGCCGCAGCTGGCCGCCGC
CGAGGTGGCCGAGCGGGCCGGCAGCATCGCGCTGCAGACCCGCCAGCGGGTGGTCGGTGTGGTGGAGAACATGTCGGGGC
TCACCCTGCCGGACGGCTCCACGTTGCAGGTGTTCGGCGAGGGCGGCGGCCAGCAGGTGGCCGAGCGGCTGTCCCGGGCG
GTCGGCGCCGAGGTGCCGCTGCTGGGTCAGATCCCGCTGGACCCCGCGCTGGTGGAGGCGGGCGATTCCGGTACCCCGCT
GGTGCTCAGCGCGCCGGATTCGCCGGTGGGCAAGGCGCTGCGCGCGGTGGCCGACAGCCTGTCGTCGCGCCGGCGCGGAC
TGGCCGGGGTGTCGCTGGGGCTCGACCCCACCCGGCGCTGA

Upstream 100 bases:

>100_bases
GGCCGGCCCCGCGCCGAACGCGCCGAAGAAGCCGGGCCCGGTCTAGCCGGCCCGCAGGGTCGCCGCCCGACGGCACCCGG
CCACCCGCCTACACTCGGCG

Downstream 100 bases:

>100_bases
CGGTTCAGGTGGCGTCGGCGTCGAACGGCGTCTGGCCGGAGCGGTGCGGCTCGGGCGGTGGCGCCGGGGCGGGCGGCGGC
TGGGCCGCGGCGCCGTTGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MMSRHDSSDSAADLSAAVRAALGKVIDPELRRPITELGMVKSIDTEPDGAVHVAIYLTTAACPKKTEISDRVTRAVADVP
GTGAVKVTLDVMSDEQRTELRKQLRGDAREPVIPFAQPNSLTRVYAVASGKGGVGKSTVTVNLAAAMAARGLSVGVLDAD
IHGHSIPRMMGTTDRPTQVESMILPPIAHDVRVISIAQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGT
GDIAISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRVVGVVENMSGLTLPDGSTLQVFGEGGGQQVAERLSRA
VGAEVPLLGQIPLDPALVEAGDSGTPLVLSAPDSPVGKALRAVADSLSSRRRGLAGVSLGLDPTRR

Sequences:

>Translated_386_residues
MMSRHDSSDSAADLSAAVRAALGKVIDPELRRPITELGMVKSIDTEPDGAVHVAIYLTTAACPKKTEISDRVTRAVADVP
GTGAVKVTLDVMSDEQRTELRKQLRGDAREPVIPFAQPNSLTRVYAVASGKGGVGKSTVTVNLAAAMAARGLSVGVLDAD
IHGHSIPRMMGTTDRPTQVESMILPPIAHDVRVISIAQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGT
GDIAISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRVVGVVENMSGLTLPDGSTLQVFGEGGGQQVAERLSRA
VGAEVPLLGQIPLDPALVEAGDSGTPLVLSAPDSPVGKALRAVADSLSSRRRGLAGVSLGLDPTRR
>Mature_386_residues
MMSRHDSSDSAADLSAAVRAALGKVIDPELRRPITELGMVKSIDTEPDGAVHVAIYLTTAACPKKTEISDRVTRAVADVP
GTGAVKVTLDVMSDEQRTELRKQLRGDAREPVIPFAQPNSLTRVYAVASGKGGVGKSTVTVNLAAAMAARGLSVGVLDAD
IHGHSIPRMMGTTDRPTQVESMILPPIAHDVRVISIAQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGT
GDIAISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRVVGVVENMSGLTLPDGSTLQVFGEGGGQQVAERLSRA
VGAEVPLLGQIPLDPALVEAGDSGTPLVLSAPDSPVGKALRAVADSLSSRRRGLAGVSLGLDPTRR

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=265, Percent_Identity=39.2452830188679, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI157384956, Length=272, Percent_Identity=38.6029411764706, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI118572611, Length=247, Percent_Identity=35.6275303643725, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI87082045, Length=372, Percent_Identity=34.9462365591398, Blast_Score=182, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI25143050, Length=256, Percent_Identity=37.5, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6322188, Length=250, Percent_Identity=36.4, Blast_Score=152, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6321347, Length=270, Percent_Identity=32.962962962963, Blast_Score=132, Evalue=9e-32,
Organism=Drosophila melanogaster, GI221511043, Length=247, Percent_Identity=35.2226720647773, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24667611, Length=260, Percent_Identity=33.8461538461538, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI19921440, Length=235, Percent_Identity=37.8723404255319, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 40409; Mature: 40409

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSRHDSSDSAADLSAAVRAALGKVIDPELRRPITELGMVKSIDTEPDGAVHVAIYLTTA
CCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHCCHHCCCCCCCCEEEEEEEEEEC
ACPKKTEISDRVTRAVADVPGTGAVKVTLDVMSDEQRTELRKQLRGDAREPVIPFAQPNS
CCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCC
LTRVYAVASGKGGVGKSTVTVNLAAAMAARGLSVGVLDADIHGHSIPRMMGTTDRPTQVE
CEEEEEEECCCCCCCCCEEEEEHHHHHHHCCCEEEEEEECCCCCCCHHHCCCCCCCCHHH
SMILPPIAHDVRVISIAQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGT
HHCCCCCCCCEEEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
GDIAISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRVVGVVENMSGLTLPDGS
CHHEEEHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
TLQVFGEGGGQQVAERLSRAVGAEVPLLGQIPLDPALVEAGDSGTPLVLSAPDSPVGKAL
EEEEEECCCHHHHHHHHHHHHCCCCCEEECCCCCHHHEECCCCCCEEEEECCCCHHHHHH
RAVADSLSSRRRGLAGVSLGLDPTRR
HHHHHHHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure
MMSRHDSSDSAADLSAAVRAALGKVIDPELRRPITELGMVKSIDTEPDGAVHVAIYLTTA
CCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHCCHHCCCCCCCCEEEEEEEEEEC
ACPKKTEISDRVTRAVADVPGTGAVKVTLDVMSDEQRTELRKQLRGDAREPVIPFAQPNS
CCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCC
LTRVYAVASGKGGVGKSTVTVNLAAAMAARGLSVGVLDADIHGHSIPRMMGTTDRPTQVE
CEEEEEEECCCCCCCCCEEEEEHHHHHHHCCCEEEEEEECCCCCCCHHHCCCCCCCCHHH
SMILPPIAHDVRVISIAQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGT
HHCCCCCCCCEEEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
GDIAISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRVVGVVENMSGLTLPDGS
CHHEEEHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
TLQVFGEGGGQQVAERLSRAVGAEVPLLGQIPLDPALVEAGDSGTPLVLSAPDSPVGKAL
EEEEEECCCHHHHHHHHHHHHCCCCCEEECCCCCHHHEECCCCCCEEEEECCCCHHHHHH
RAVADSLSSRRRGLAGVSLGLDPTRR
HHHHHHHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]