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The map label for this gene is corA

Identifier: 41408640

GI number: 41408640

Start: 2859417

End: 2860517

Strand: Direct

Name: corA

Synonym: MAP2542

Alternate gene names: 41408640

Gene position: 2859417-2860517 (Clockwise)

Preceding gene: 41408636

Following gene: 41408641

Centisome position: 59.2

GC content: 65.94

Gene sequence:

>1101_bases
GTGTTCCAGGGATTCGACGCATTGCCCGAAGTGCTTCGGCCCATCGCCCACCAACCGCACCCGCAGCCGGCGCCCGAGGC
CCCGCCGGCCCGCGCGACGCTGGTCGACTGCGCGGTGTACGACGACGGGAACCGGCTGCCCGGCGTGTTCGGTTACGCCG
ACGCCCTGGACAAGGTCCGCGAGATCGAATCCCAGGGGCGCGAGGGATTCGTCTGGGTCGGCCTGCGCGAACCGAACCAG
ACCGAAATGCAGGAAGTGGCAGACGTTTTCGGGCTGCACGCGCTGGCCGTCGAGGACGCCGTGTGCGCCCATCAGCGGCC
CAAGGTGGAGCGCTACGACGACACACTGTTTCTGGTGCTCAAGACCGTCAACTACGTGCCGCACGAATCGGTGGTGCTGG
CCCGCGAGATCGTCGAGACCGGCGAGATCATGGTGTTCGTCGGCCGCGATTTCGTGGTGACCGTCCGGCACGGCGAACAC
GGCGGGCTGTCCGAGGTGCGCAAGCGGATGGACGGCGACCCCGAGCAAATGCGGCTGGGCCCGTTCGCGGTGATGCACGC
GATCGCCGACCACGTGGTGGACCACTATCTCGAGGTGAGCAGCTTGATGCTCGCCGACATCGACAGCATCGAGGGGTTGG
CGTTCGCCCCGGGCAGCAAGATCGACGTCGAACCGATCTATCTGCTCAAGCGCGAGGTCGTCGAACTGCGCCGCTGCGTC
AACCCGCTGTCGTCGGCGTTTCACCGGATCCAGACCGAGAACAAGGACGTGATCTCCAAGGAGGTGCGCCGCTATCTGCG
CGACGTCGCCGATCACCACTCCGAGGCCGCCGACCAGATCGCCAGCTACGACGACATGCTCAACTCGCTGATCCAGGCGG
CCCTGGCCCGGGTGGGGATGCAGCAGAACAACGACATGCGCAAGATGGCGGCCTGGGCCGGCATCTTGGCGGTGCCGACC
ATGATCGCCGCCATTTACGGGATGAACTTCCATTTCATGCCCGAGCTCAACTGGACCTGGGGATACCCGGCGGTGATGGC
GGGCATGGCCGTCGTCTGCCTGGTGCTGTACTTCCAGTTCCGCAACCGCAACTGGCTCTAG

Upstream 100 bases:

>100_bases
GCTACCAGGGCTTTCCGCCGCGCGATCGTCACGCCGGCCGGCGCCGGGACGCGTAGCATGAGCACCGCCTGGTCTGACCT
GCGCTGCGTGGGAGGTGGAT

Downstream 100 bases:

>100_bases
CGCTCGCTTTTCCCGCGAGTTCCTCCGCGAGCAGACGCAAAAGCCCCTCGACGCCCGGCGTGTCGGGGGCTTTTGCGTCT
GCTCGAGGGAGGGGGTGGGG

Product: hypothetical protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MFQGFDALPEVLRPIAHQPHPQPAPEAPPARATLVDCAVYDDGNRLPGVFGYADALDKVREIESQGREGFVWVGLREPNQ
TEMQEVADVFGLHALAVEDAVCAHQRPKVERYDDTLFLVLKTVNYVPHESVVLAREIVETGEIMVFVGRDFVVTVRHGEH
GGLSEVRKRMDGDPEQMRLGPFAVMHAIADHVVDHYLEVSSLMLADIDSIEGLAFAPGSKIDVEPIYLLKREVVELRRCV
NPLSSAFHRIQTENKDVISKEVRRYLRDVADHHSEAADQIASYDDMLNSLIQAALARVGMQQNNDMRKMAAWAGILAVPT
MIAAIYGMNFHFMPELNWTWGYPAVMAGMAVVCLVLYFQFRNRNWL

Sequences:

>Translated_366_residues
MFQGFDALPEVLRPIAHQPHPQPAPEAPPARATLVDCAVYDDGNRLPGVFGYADALDKVREIESQGREGFVWVGLREPNQ
TEMQEVADVFGLHALAVEDAVCAHQRPKVERYDDTLFLVLKTVNYVPHESVVLAREIVETGEIMVFVGRDFVVTVRHGEH
GGLSEVRKRMDGDPEQMRLGPFAVMHAIADHVVDHYLEVSSLMLADIDSIEGLAFAPGSKIDVEPIYLLKREVVELRRCV
NPLSSAFHRIQTENKDVISKEVRRYLRDVADHHSEAADQIASYDDMLNSLIQAALARVGMQQNNDMRKMAAWAGILAVPT
MIAAIYGMNFHFMPELNWTWGYPAVMAGMAVVCLVLYFQFRNRNWL
>Mature_366_residues
MFQGFDALPEVLRPIAHQPHPQPAPEAPPARATLVDCAVYDDGNRLPGVFGYADALDKVREIESQGREGFVWVGLREPNQ
TEMQEVADVFGLHALAVEDAVCAHQRPKVERYDDTLFLVLKTVNYVPHESVVLAREIVETGEIMVFVGRDFVVTVRHGEH
GGLSEVRKRMDGDPEQMRLGPFAVMHAIADHVVDHYLEVSSLMLADIDSIEGLAFAPGSKIDVEPIYLLKREVVELRRCV
NPLSSAFHRIQTENKDVISKEVRRYLRDVADHHSEAADQIASYDDMLNSLIQAALARVGMQQNNDMRKMAAWAGILAVPT
MIAAIYGMNFHFMPELNWTWGYPAVMAGMAVVCLVLYFQFRNRNWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=109, Percent_Identity=34.8623853211009, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 41163; Mature: 41163

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQGFDALPEVLRPIAHQPHPQPAPEAPPARATLVDCAVYDDGNRLPGVFGYADALDKVR
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHH
EIESQGREGFVWVGLREPNQTEMQEVADVFGLHALAVEDAVCAHQRPKVERYDDTLFLVL
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHH
KTVNYVPHESVVLAREIVETGEIMVFVGRDFVVTVRHGEHGGLSEVRKRMDGDPEQMRLG
HHHCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHH
PFAVMHAIADHVVDHYLEVSSLMLADIDSIEGLAFAPGSKIDVEPIYLLKREVVELRRCV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHH
NPLSSAFHRIQTENKDVISKEVRRYLRDVADHHSEAADQIASYDDMLNSLIQAALARVGM
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QQNNDMRKMAAWAGILAVPTMIAAIYGMNFHFMPELNWTWGYPAVMAGMAVVCLVLYFQF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
RNRNWL
HCCCCC
>Mature Secondary Structure
MFQGFDALPEVLRPIAHQPHPQPAPEAPPARATLVDCAVYDDGNRLPGVFGYADALDKVR
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHH
EIESQGREGFVWVGLREPNQTEMQEVADVFGLHALAVEDAVCAHQRPKVERYDDTLFLVL
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHH
KTVNYVPHESVVLAREIVETGEIMVFVGRDFVVTVRHGEHGGLSEVRKRMDGDPEQMRLG
HHHCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHH
PFAVMHAIADHVVDHYLEVSSLMLADIDSIEGLAFAPGSKIDVEPIYLLKREVVELRRCV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHH
NPLSSAFHRIQTENKDVISKEVRRYLRDVADHHSEAADQIASYDDMLNSLIQAALARVGM
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QQNNDMRKMAAWAGILAVPTMIAAIYGMNFHFMPELNWTWGYPAVMAGMAVVCLVLYFQF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
RNRNWL
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]