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The map label for this gene is kgd

Identifier: 41408634

GI number: 41408634

Start: 2850460

End: 2854203

Strand: Direct

Name: kgd

Synonym: MAP2536

Alternate gene names: 41408634

Gene position: 2850460-2854203 (Clockwise)

Preceding gene: 41408633

Following gene: 41408635

Centisome position: 59.02

GC content: 67.36

Gene sequence:

>3744_bases
GTGAGCAACATAAGTTCACCATTCGGGCAGAACGAATGGCTGGTCGAGGAGATGTACCGCAAGTTCCGCGACGACCCCTC
GTCGGTCGATCCGAGCTGGCACGAATTCCTCGTCGACTACAACCCCGAGCCCACCGGCGACTCGGTGCTGGCCGCCCCGG
CCAGCACCGACGGCCCGTCCGCCCCGGCGCCGGCTGCCCCGCAAACCGCCCAGCCCGCCCTGCCCGCCCAAACGGCCCCG
CCGGCTCAGACCGCCCAGCCGGCCCGGCCCGCGCCCCAGCCCGCCGCGGCCCCGGGCAACGGGGCGAGCACCCGCCCGGC
CAAGCCCGCCACTCCCCCGCCGGCCGAGGGTGACGAGCTGCAGACGTTGCGCGGCGCCGCCGCGGCCGTCGTCAAGAACA
TGTCCGCGTCGCTGGAGGTGCCGACGGCCACCAGCGTGCGCGCCATCCCGGCCAAACTGCTGATCGACAACCGGATCGTC
ATCAACAACCAGCTCAAGCGCACCCGCGGCGGCAAGATCTCGTTCACTCACCTGTTGGGCTACGCGCTGGTGCAGGCGAT
CAAGAAGTTCCCGAACATGAATCGGCACTACGCCGAGATCGACGGCAAACCCACCGCGATCACCCCGGCGCACACCAACC
TGGGCCTGGCCATCGATCTGCAGGGCAAGGACGGCAAGCGGTCGTTGGTGGTGGCCGGCATCAAGAACTGCGAGACCATG
CGGTTCGCCCAGTTCGTCACCGCCTACGAGGACATCGTGCGGCGGGCCCGCGACGGCAAGCTGACCGCCGAAGACTTTGC
CGGCGTGACGATTTCGCTCACCAACCCCGGCACCATCGGCACCGTGCACTCGGTGCCGCGGCTGATGAACGGCCAGGGCG
CCATCATCGGCGTGGGCGCGATGGAGTACCCCGCCGAATTCCAGGGGGCCAGCGAGGAACGCATCGCCGAACTGGGCATC
GGCAAGCTGATCACACTGACCTCGACCTACGACCACCGCATCATCCAGGGCGCGGAATCCGGTGACTTCCTGCGCACCAT
CCACGAGATGCTGCTGTCGGACGGGTTCTGGGACGACATCTTCCGCGAGCTGAGCATCCCGTACCTGCCGATCCGGTGGA
GCACCGACAACCCGGACTCGATCGTCGACAAGAACGCCCGGGTGATGGAGTTGATCGCGGCCTACCGCAACCGCGGGCAC
CTGATGGCCGACATCGACCCGCTGCGGTTGGACGGCAGCCGGTTCCGCAGCCACCCCGATCTGGAGATCCTCAACCACGG
CCTGACGCTGTGGGACCTGGACCGGGTGTTCAAGGTCAACGGCTTCGCCGGGGCGGAGTACAAGAAGCTGCGCGACATCC
TGGGCCTGCTGCGGGATGCGTACTGCCGCCACATCGGCGTGGAGTACACCCACATCCTCGACCCCGAGCAGCAGGAATGG
CTGCAGCAGCGGGTCGAGACCAAACACGTCAAGCCGACGGTGGCCGAGCAGAAGTTCATCCTGAGCAAGCTGAACGCGGC
CGAGGCCTTCGAGACCTTCTTGCAGACCAAATACGTTGGGCAGAAACGCTTTTCGCTGGAAGGCGCGGAAAGTGTGATCC
CGATGATGGACGCGGCGATCGATCAGTGCGCCGAGCACGGGCTCGACGAAGTGGTGATCGGGATGCCGCACCGCGGCCGG
CTCAACGTGCTGGCCAACATCGTCGGCAAGCCGTACTCGCAGATCTTCTCCGAGTTCGAGGGCAACCTCAACCCGGCGCA
GGCGCACGGCTCCGGCGACGTCAAGTACCACCTGGGCGCCACCGGCGTGTACCTACAGATGTTCGGCGACAACGACATTC
AGGTGTCGTTGACCGCCAACCCGTCGCACCTGGAGGCCGTCGACCCGGTGCTGGAGGGTCTGGTCCGGGCCAAGCAGGAC
CTGCTGGATCACGGCGCCGACGACCAGGGAGACGAGAAGGCCTTCTCGGTGGTGCCGATGATGCTGCACGGCGATGCCGC
GTTCGCCGGCCAGGGCGTGGTGGCCGAGACACTGAACCTGACCCATCTGCCCGGCTACCGGGTCGGCGGCACCATCCACA
TCATCGTCAACAACCAGATCGGCTTCACCACGGCGCCGGAGCACTCCCGCTCCAGCGAGTACTGCACCGACGTCGCCAAG
ATGATCGGGGCCCCCATCTTCCACGTCAACGGCGACGACCCGGAGGCCTGCGCGTGGGTGGCCAAGCTGGCCGTCGACTT
CCGGCAGAAATTCAAGAAGGACGTCGTCATCGACATGCTGTGCTACCGCAAGCGCGGGCACAACGAGGGCGACGACCCGT
CGATGACCAACCCGGCCATGTACGACGTCGTCGACATCAAGCGCGGGGTGCGCAAGAGCTACACCGAGGCGCTGATCGGC
CGCGGCGACATCTCGATGAAAGAGGCCGAGGACGCGCTGCGCGACTACCAGGGCCAGCTGGAGCGGGTGTTCAACGAGGT
CCGCGAACTGGAGAAGCACGGCGTGGGGCCCAGCGAGTCGGTGGAAGCCGACCAGATGCTGCCCGCGGGCCTGGCCACCG
CGGTGGACAAGGCGCTGCTGGCCCGCATCGGCGACGCGTTCCTGGCGCTGCCGGAGGGTTTCACCGCCCACCCTCGGGTG
CAGCCGGTACTGGAGAAGCGCCGGGAGATGGCCTACGAGGGCAAGATCGACTGGGCCTTCGCCGAACTGCTGGCGCTGGG
CTCGCTGGTGGCCGGGGGCAAGCTGGTGCGGCTGTCCGGGCAGGACACCCGGCGCGGCACCTTCTCGCAACGGCACTCGG
TGATCATCGACCGCAACACCGGCGAGGAGTTCACCCCGCTGCAGTTGCTGGCGACCAACCCCGACGGCACCCCGACCGGC
GGCAAATTCCTGGTGTATGACTCCCCGCTGTCGGAGTACGCGGCCGTCGGCTTCGAGTACGGCTACACCGTGGGCAACCC
CGACGCCCTGGTGCTGTGGGAGGCGCAGTTCGGCGACTTCGTCAACGGCGCGCAGTCGATCATCGACGAGTTCATCAGCT
CGGGTGAGGCCAAGTGGGGTCAGCTGTCCAACGTCGTGCTGTTGCTGCCGCACGGGCACGAGGGCCAGGGCCCCGACCAC
ACCTCGGCGCGCATCGAGCGCTTCCTGCAGCTGTGGGCGGAGGGGTCGATGACGATCGCGATGCCGTCCACCCCGTCCAA
CTACTTCCACCTGTTGCGCCGGCACGCCCTGGACGGGATCAAGCGGCCGCTGATCGTGTTCACCCCGAAGTCGATGCTGC
GCAACAAGGCCGCGGTCAGCGACATCAAGGACTTCACCGAGATCAAGTTCCGCTCGGTGCTCGAGGAGCCGACCTACGAG
GACGGCATCGGCGATCGCGGCAAGGTCAGCCGGGTGCTGTTGACCAGCGGCAAGCTCTACTACGAGCTGGTCGCGCGCAA
GAACAAGGACAACCGCGACGACGTGGCGATCGTGCGGATCGAACAGCTGGCCCCGCTGCCCAAGCGCCGGCTGGGCGAGA
CGCTGGACCGCTATCCGAACGTGCGCGAGTACTTCTGGGTGCAGGAGGAGCCGGCCAACCAGGGGGCCTGGCCGCGATTC
GGCCTGGAGCTGCCCGAGCTGCTGCCCGACAAGCTGACCGGGCTCAAGCGGATTTCCCGCCGGGCGATGTCGGCGCCGTC
GTCGGGCTCGTCGAAGGTGCACGCCGTCGAGCAGCAGGAGATCATCGACACCGCCTTCGCCTGA

Upstream 100 bases:

>100_bases
TGTGGGGTGCTCGGGCACCCGGGACCGACAAGAGGGCAGGCGCCGCGGAACAGCGCTGCGGTGACCCTGCGGGACAACGG
GATTGAGGCGAACTGCGGTC

Downstream 100 bases:

>100_bases
GGCGTCGACGGGTCCTCAGCGTCACGCCAGCGTGGCGCTCGGGTCCCGGCGCCACGCTGGCGTGACGCTCGGCGAGGCGG
GCGGCGTGGATGCGCGCACC

Product: alpha-ketoglutarate decarboxylase

Products: NA

Alternate protein names: 2-oxoglutarate carboxy-lyase; Alpha-ketoglutarate decarboxylase

Number of amino acids: Translated: 1247; Mature: 1246

Protein sequence:

>1247_residues
MSNISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPTGDSVLAAPASTDGPSAPAPAAPQTAQPALPAQTAP
PAQTAQPARPAPQPAAAPGNGASTRPAKPATPPPAEGDELQTLRGAAAAVVKNMSASLEVPTATSVRAIPAKLLIDNRIV
INNQLKRTRGGKISFTHLLGYALVQAIKKFPNMNRHYAEIDGKPTAITPAHTNLGLAIDLQGKDGKRSLVVAGIKNCETM
RFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMNGQGAIIGVGAMEYPAEFQGASEERIAELGI
GKLITLTSTYDHRIIQGAESGDFLRTIHEMLLSDGFWDDIFRELSIPYLPIRWSTDNPDSIVDKNARVMELIAAYRNRGH
LMADIDPLRLDGSRFRSHPDLEILNHGLTLWDLDRVFKVNGFAGAEYKKLRDILGLLRDAYCRHIGVEYTHILDPEQQEW
LQQRVETKHVKPTVAEQKFILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGR
LNVLANIVGKPYSQIFSEFEGNLNPAQAHGSGDVKYHLGATGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQD
LLDHGADDQGDEKAFSVVPMMLHGDAAFAGQGVVAETLNLTHLPGYRVGGTIHIIVNNQIGFTTAPEHSRSSEYCTDVAK
MIGAPIFHVNGDDPEACAWVAKLAVDFRQKFKKDVVIDMLCYRKRGHNEGDDPSMTNPAMYDVVDIKRGVRKSYTEALIG
RGDISMKEAEDALRDYQGQLERVFNEVRELEKHGVGPSESVEADQMLPAGLATAVDKALLARIGDAFLALPEGFTAHPRV
QPVLEKRREMAYEGKIDWAFAELLALGSLVAGGKLVRLSGQDTRRGTFSQRHSVIIDRNTGEEFTPLQLLATNPDGTPTG
GKFLVYDSPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDH
TSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIKRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYE
DGIGDRGKVSRVLLTSGKLYYELVARKNKDNRDDVAIVRIEQLAPLPKRRLGETLDRYPNVREYFWVQEEPANQGAWPRF
GLELPELLPDKLTGLKRISRRAMSAPSSGSSKVHAVEQQEIIDTAFA

Sequences:

>Translated_1247_residues
MSNISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPTGDSVLAAPASTDGPSAPAPAAPQTAQPALPAQTAP
PAQTAQPARPAPQPAAAPGNGASTRPAKPATPPPAEGDELQTLRGAAAAVVKNMSASLEVPTATSVRAIPAKLLIDNRIV
INNQLKRTRGGKISFTHLLGYALVQAIKKFPNMNRHYAEIDGKPTAITPAHTNLGLAIDLQGKDGKRSLVVAGIKNCETM
RFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMNGQGAIIGVGAMEYPAEFQGASEERIAELGI
GKLITLTSTYDHRIIQGAESGDFLRTIHEMLLSDGFWDDIFRELSIPYLPIRWSTDNPDSIVDKNARVMELIAAYRNRGH
LMADIDPLRLDGSRFRSHPDLEILNHGLTLWDLDRVFKVNGFAGAEYKKLRDILGLLRDAYCRHIGVEYTHILDPEQQEW
LQQRVETKHVKPTVAEQKFILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGR
LNVLANIVGKPYSQIFSEFEGNLNPAQAHGSGDVKYHLGATGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQD
LLDHGADDQGDEKAFSVVPMMLHGDAAFAGQGVVAETLNLTHLPGYRVGGTIHIIVNNQIGFTTAPEHSRSSEYCTDVAK
MIGAPIFHVNGDDPEACAWVAKLAVDFRQKFKKDVVIDMLCYRKRGHNEGDDPSMTNPAMYDVVDIKRGVRKSYTEALIG
RGDISMKEAEDALRDYQGQLERVFNEVRELEKHGVGPSESVEADQMLPAGLATAVDKALLARIGDAFLALPEGFTAHPRV
QPVLEKRREMAYEGKIDWAFAELLALGSLVAGGKLVRLSGQDTRRGTFSQRHSVIIDRNTGEEFTPLQLLATNPDGTPTG
GKFLVYDSPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDH
TSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIKRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYE
DGIGDRGKVSRVLLTSGKLYYELVARKNKDNRDDVAIVRIEQLAPLPKRRLGETLDRYPNVREYFWVQEEPANQGAWPRF
GLELPELLPDKLTGLKRISRRAMSAPSSGSSKVHAVEQQEIIDTAFA
>Mature_1246_residues
SNISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPTGDSVLAAPASTDGPSAPAPAAPQTAQPALPAQTAPP
AQTAQPARPAPQPAAAPGNGASTRPAKPATPPPAEGDELQTLRGAAAAVVKNMSASLEVPTATSVRAIPAKLLIDNRIVI
NNQLKRTRGGKISFTHLLGYALVQAIKKFPNMNRHYAEIDGKPTAITPAHTNLGLAIDLQGKDGKRSLVVAGIKNCETMR
FAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMNGQGAIIGVGAMEYPAEFQGASEERIAELGIG
KLITLTSTYDHRIIQGAESGDFLRTIHEMLLSDGFWDDIFRELSIPYLPIRWSTDNPDSIVDKNARVMELIAAYRNRGHL
MADIDPLRLDGSRFRSHPDLEILNHGLTLWDLDRVFKVNGFAGAEYKKLRDILGLLRDAYCRHIGVEYTHILDPEQQEWL
QQRVETKHVKPTVAEQKFILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRL
NVLANIVGKPYSQIFSEFEGNLNPAQAHGSGDVKYHLGATGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDL
LDHGADDQGDEKAFSVVPMMLHGDAAFAGQGVVAETLNLTHLPGYRVGGTIHIIVNNQIGFTTAPEHSRSSEYCTDVAKM
IGAPIFHVNGDDPEACAWVAKLAVDFRQKFKKDVVIDMLCYRKRGHNEGDDPSMTNPAMYDVVDIKRGVRKSYTEALIGR
GDISMKEAEDALRDYQGQLERVFNEVRELEKHGVGPSESVEADQMLPAGLATAVDKALLARIGDAFLALPEGFTAHPRVQ
PVLEKRREMAYEGKIDWAFAELLALGSLVAGGKLVRLSGQDTRRGTFSQRHSVIIDRNTGEEFTPLQLLATNPDGTPTGG
KFLVYDSPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHT
SARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIKRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYED
GIGDRGKVSRVLLTSGKLYYELVARKNKDNRDDVAIVRIEQLAPLPKRRLGETLDRYPNVREYFWVQEEPANQGAWPRFG
LELPELLPDKLTGLKRISRRAMSAPSSGSSKVHAVEQQEIIDTAFA

Specific function: Catalyzes an oxidative decarboxylation from five-carbon 2-oxoglutarate (alpha-ketoglutarate) to four-carbon succinate semialdehyde

COG id: COG0567

COG function: function code C; 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 2-oxoacid dehydrogenase family. Kgd subfamily

Homologues:

Organism=Homo sapiens, GI259013553, Length=914, Percent_Identity=42.0131291028446, Blast_Score=670, Evalue=0.0,
Organism=Homo sapiens, GI51873036, Length=918, Percent_Identity=41.7211328976035, Blast_Score=667, Evalue=0.0,
Organism=Homo sapiens, GI221316661, Length=917, Percent_Identity=40.7851690294438, Blast_Score=651, Evalue=0.0,
Organism=Homo sapiens, GI221316665, Length=905, Percent_Identity=40.6629834254144, Blast_Score=642, Evalue=0.0,
Organism=Homo sapiens, GI221316669, Length=815, Percent_Identity=42.0858895705521, Blast_Score=611, Evalue=1e-174,
Organism=Homo sapiens, GI38788380, Length=891, Percent_Identity=37.7104377104377, Blast_Score=579, Evalue=1e-165,
Organism=Homo sapiens, GI51873038, Length=275, Percent_Identity=43.2727272727273, Blast_Score=213, Evalue=9e-55,
Organism=Homo sapiens, GI110671329, Length=245, Percent_Identity=27.3469387755102, Blast_Score=75, Evalue=6e-13,
Organism=Homo sapiens, GI19923748, Length=123, Percent_Identity=34.1463414634146, Blast_Score=67, Evalue=9e-11,
Organism=Escherichia coli, GI1786945, Length=896, Percent_Identity=43.5267857142857, Blast_Score=708, Evalue=0.0,
Organism=Escherichia coli, GI1786946, Length=221, Percent_Identity=29.4117647058824, Blast_Score=87, Evalue=8e-18,
Organism=Escherichia coli, GI1786305, Length=186, Percent_Identity=26.8817204301075, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17542494, Length=911, Percent_Identity=41.2733260153677, Blast_Score=663, Evalue=0.0,
Organism=Caenorhabditis elegans, GI72001668, Length=899, Percent_Identity=35.706340378198, Blast_Score=536, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI25146366, Length=122, Percent_Identity=33.6065573770492, Blast_Score=70, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17537937, Length=331, Percent_Identity=24.773413897281, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322066, Length=955, Percent_Identity=39.6858638743456, Blast_Score=650, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320352, Length=325, Percent_Identity=25.5384615384615, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324258, Length=224, Percent_Identity=26.3392857142857, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28574590, Length=928, Percent_Identity=40.301724137931, Blast_Score=638, Evalue=0.0,
Organism=Drosophila melanogaster, GI161084450, Length=928, Percent_Identity=40.301724137931, Blast_Score=638, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665669, Length=919, Percent_Identity=40.1523394994559, Blast_Score=634, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665673, Length=919, Percent_Identity=40.1523394994559, Blast_Score=634, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665677, Length=919, Percent_Identity=40.1523394994559, Blast_Score=634, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574592, Length=919, Percent_Identity=40.1523394994559, Blast_Score=634, Evalue=0.0,
Organism=Drosophila melanogaster, GI161084461, Length=872, Percent_Identity=41.5137614678899, Blast_Score=632, Evalue=0.0,
Organism=Drosophila melanogaster, GI78706592, Length=925, Percent_Identity=39.6756756756757, Blast_Score=627, Evalue=1e-179,
Organism=Drosophila melanogaster, GI78706596, Length=925, Percent_Identity=39.6756756756757, Blast_Score=627, Evalue=1e-179,
Organism=Drosophila melanogaster, GI281365454, Length=925, Percent_Identity=39.6756756756757, Blast_Score=627, Evalue=1e-179,
Organism=Drosophila melanogaster, GI281365452, Length=925, Percent_Identity=39.6756756756757, Blast_Score=627, Evalue=1e-179,
Organism=Drosophila melanogaster, GI78706594, Length=947, Percent_Identity=38.7539598732841, Blast_Score=614, Evalue=1e-175,
Organism=Drosophila melanogaster, GI78706598, Length=947, Percent_Identity=38.7539598732841, Blast_Score=614, Evalue=1e-175,
Organism=Drosophila melanogaster, GI24651589, Length=896, Percent_Identity=36.8303571428571, Blast_Score=536, Evalue=1e-152,
Organism=Drosophila melanogaster, GI161079314, Length=758, Percent_Identity=39.3139841688654, Blast_Score=499, Evalue=1e-141,
Organism=Drosophila melanogaster, GI24651591, Length=758, Percent_Identity=39.3139841688654, Blast_Score=499, Evalue=1e-141,
Organism=Drosophila melanogaster, GI18859875, Length=268, Percent_Identity=29.1044776119403, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24645909, Length=180, Percent_Identity=31.1111111111111, Blast_Score=70, Evalue=7e-12,

Paralogues:

None

Copy number: 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): KGD_MYCPA (Q73WX4)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_961470.1
- ProteinModelPortal:   Q73WX4
- EnsemblBacteria:   EBMYCT00000038281
- GeneID:   2719042
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP2536
- NMPDR:   fig|262316.1.peg.2536
- GeneTree:   EBGT00050000014858
- HOGENOM:   HBG289950
- OMA:   EGDEPAF
- ProtClustDB:   PRK12270
- BRENDA:   4.1.1.71
- GO:   GO:0006096
- InterPro:   IPR001078
- InterPro:   IPR011603
- InterPro:   IPR023213
- InterPro:   IPR001017
- InterPro:   IPR005475
- Gene3D:   G3DSA:3.30.559.10
- PANTHER:   PTHR23152
- PIRSF:   PIRSF000157
- SMART:   SM00861
- TIGRFAMs:   TIGR00239

Pfam domain/function: PF00198 2-oxoacid_dh; PF00676 E1_dh; PF02779 Transket_pyr

EC number: =4.1.1.71

Molecular weight: Translated: 137075; Mature: 136944

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPTGDSVLAAPASTDGPS
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHEEECCCCCCCCCEEECCCCCCCCC
APAPAAPQTAQPALPAQTAPPAQTAQPARPAPQPAAAPGNGASTRPAKPATPPPAEGDEL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QTLRGAAAAVVKNMSASLEVPTATSVRAIPAKLLIDNRIVINNQLKRTRGGKISFTHLLG
HHHHHHHHHHHHHCCCCEECCCCCCHHHCCHHHEECCEEEECCCHHHCCCCCEEHHHHHH
YALVQAIKKFPNMNRHYAEIDGKPTAITPAHTNLGLAIDLQGKDGKRSLVVAGIKNCETM
HHHHHHHHHCCCCCCEEEECCCCCCEECCCCCCCEEEEEECCCCCCCEEEEEECCCCHHH
RFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMNGQGAIIGVGA
HHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCCEEECCC
MEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHEMLLSDGFWDDI
CCCCHHHCCCCHHHHHHHCCCCEEEEECCCCHHHHCCCCCCHHHHHHHHHHHCCCCHHHH
FRELSIPYLPIRWSTDNPDSIVDKNARVMELIAAYRNRGHLMADIDPLRLDGSRFRSHPD
HHHHCCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHCCCCEEECCCCEEECHHHHCCCCC
LEILNHGLTLWDLDRVFKVNGFAGAEYKKLRDILGLLRDAYCRHIGVEYTHILDPEQQEW
HHHHHCCCEEEECHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHH
LQQRVETKHVKPTVAEQKFILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHH
DQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPAQAHGSGDVKYHLGA
HHHHHCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHCCCCCCEEEEECC
TGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGADDQGDEKAFSVVPM
CEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MLHGDAAFAGQGVVAETLNLTHLPGYRVGGTIHIIVNNQIGFTTAPEHSRSSEYCTDVAK
EEECCCHHCCCCHHHHHCCCCCCCCEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
MIGAPIFHVNGDDPEACAWVAKLAVDFRQKFKKDVVIDMLCYRKRGHNEGDDPSMTNPAM
HHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
YDVVDIKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGVGPSES
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VEADQMLPAGLATAVDKALLARIGDAFLALPEGFTAHPRVQPVLEKRREMAYEGKIDWAF
CCHHHHCCHHHHHHHHHHHHHHHCHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
AELLALGSLVAGGKLVRLSGQDTRRGTFSQRHSVIIDRNTGEEFTPLQLLATNPDGTPTG
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCC
GKFLVYDSPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWG
CEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEECHHCHHHHHHHHHHHHHHHCCCCCCC
QLSNVVLLLPHGHEGQGPDHTSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGI
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
KRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYEDGIGDRGKVSRVLLTSGKLY
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHH
YELVARKNKDNRDDVAIVRIEQLAPLPKRRLGETLDRYPNVREYFWVQEEPANQGAWPRF
HHHHHHCCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCC
GLELPELLPDKLTGLKRISRRAMSAPSSGSSKVHAVEQQEIIDTAFA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCC
>Mature Secondary Structure 
SNISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPTGDSVLAAPASTDGPS
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHEEECCCCCCCCCEEECCCCCCCCC
APAPAAPQTAQPALPAQTAPPAQTAQPARPAPQPAAAPGNGASTRPAKPATPPPAEGDEL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QTLRGAAAAVVKNMSASLEVPTATSVRAIPAKLLIDNRIVINNQLKRTRGGKISFTHLLG
HHHHHHHHHHHHHCCCCEECCCCCCHHHCCHHHEECCEEEECCCHHHCCCCCEEHHHHHH
YALVQAIKKFPNMNRHYAEIDGKPTAITPAHTNLGLAIDLQGKDGKRSLVVAGIKNCETM
HHHHHHHHHCCCCCCEEEECCCCCCEECCCCCCCEEEEEECCCCCCCEEEEEECCCCHHH
RFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMNGQGAIIGVGA
HHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCCEEECCC
MEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHEMLLSDGFWDDI
CCCCHHHCCCCHHHHHHHCCCCEEEEECCCCHHHHCCCCCCHHHHHHHHHHHCCCCHHHH
FRELSIPYLPIRWSTDNPDSIVDKNARVMELIAAYRNRGHLMADIDPLRLDGSRFRSHPD
HHHHCCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHCCCCEEECCCCEEECHHHHCCCCC
LEILNHGLTLWDLDRVFKVNGFAGAEYKKLRDILGLLRDAYCRHIGVEYTHILDPEQQEW
HHHHHCCCEEEECHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHH
LQQRVETKHVKPTVAEQKFILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHH
DQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPAQAHGSGDVKYHLGA
HHHHHCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHCCCCCCEEEEECC
TGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGADDQGDEKAFSVVPM
CEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MLHGDAAFAGQGVVAETLNLTHLPGYRVGGTIHIIVNNQIGFTTAPEHSRSSEYCTDVAK
EEECCCHHCCCCHHHHHCCCCCCCCEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
MIGAPIFHVNGDDPEACAWVAKLAVDFRQKFKKDVVIDMLCYRKRGHNEGDDPSMTNPAM
HHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
YDVVDIKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGVGPSES
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VEADQMLPAGLATAVDKALLARIGDAFLALPEGFTAHPRVQPVLEKRREMAYEGKIDWAF
CCHHHHCCHHHHHHHHHHHHHHHCHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
AELLALGSLVAGGKLVRLSGQDTRRGTFSQRHSVIIDRNTGEEFTPLQLLATNPDGTPTG
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCC
GKFLVYDSPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWG
CEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEECHHCHHHHHHHHHHHHHHHCCCCCCC
QLSNVVLLLPHGHEGQGPDHTSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGI
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
KRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYEDGIGDRGKVSRVLLTSGKLY
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHH
YELVARKNKDNRDDVAIVRIEQLAPLPKRRLGETLDRYPNVREYFWVQEEPANQGAWPRF
HHHHHHCCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCC
GLELPELLPDKLTGLKRISRRAMSAPSSGSSKVHAVEQQEIIDTAFA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA