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The map label for this gene is erg3 [H]

Identifier: 41407623

GI number: 41407623

Start: 1675815

End: 1676699

Strand: Direct

Name: erg3 [H]

Synonym: MAP1525

Alternate gene names: 41407623

Gene position: 1675815-1676699 (Clockwise)

Preceding gene: 41407622

Following gene: 41407624

Centisome position: 34.7

GC content: 66.33

Gene sequence:

>885_bases
CTGCGCGACCCGGTGCTGGTGGCCATTCCGTTCTTCCTGTTGTTGCTGACGCTCGAATGGACCGCGGCCCGCAAGCTGGA
ACACCTCACCGCCCGTCCGGCCCCGGGGGCGCACCAGACCCGCGACTCGCTGACCAGCATTTCGATGGGCTTGGTGTCGG
TGGCCACCACCGCGGGCTGGAAGACGCTGGCCCTGTTCGGCTACGCCGCGATCTACGCCTACCTGGCACCGTGGCACCTT
CCGGCGACCCGCTGGTACACCTGGGCGATCGCGATTCTCGGCGTCGACCTGCTCTACTACGCCTATCACCGGATCGCGCA
CCGGGTGCGGCTGATCTGGGCGACGCACCAGGCCCACCACTCCAGCGAGTACTACAACTTCGCCACCGCACTGCGCCAGA
AGTGGAACAACAGCGGCGAGATCTTGATGTGGCTTCCGTTGCCGCTGTTGGGGATTCCGCCGTGGATGGTGTTCTTCAGC
TTCTCGGTGAACCTGATTTACCAGTTCTGGATCCACACCGAGCGGATCGACAAGCTGCCCCGCCCGTTCGAGTTCGTGTT
CAACACGCCGTCGCACCACCGGGTGCACCACGGCATGGACAAGGTATACCTGGACAAGAACTACGGCGGCATCCTCATCG
TGTGGGACCGGCTGTTCGGCACCTTCCAGGCCGAGCTGTTCCGCCCGCACTACGGCCTGACCAAGCACGTCGACACCTTC
AACGTCTGGACGCTGCAGACCCGCGAATCCGTCGCCATCGCCCGCGACTGGCGGTCGGCGAGCCGGTTGCGGGACCGGTT
GGGCTACGTGTTCGGGCCGCCCGGCTGGGCACCGCGCAGCGCCGGCCGAACCGCGGCCGGCGCGCCCGTCGTGACCTCTC
TGTAA

Upstream 100 bases:

>100_bases
GCGCAGGCGTCCGACGATCGGCGCTGAGCGCCGCGGCGTTCGTCGTACGCTTACCGGTGTGAGCGCCCTGTCCGGCTACC
TGACCGCGCTGCCGCCGCAG

Downstream 100 bases:

>100_bases
CATCGGCGCTGGCCGGCGCGAAAAGCTGAGCGTGGAGGACGGTTACGCCGTAACCTCGACCTCCCGTCGGTAGTTGGCCC
GATGGATCGGAGTTCATGGT

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MRDPVLVAIPFFLLLLTLEWTAARKLEHLTARPAPGAHQTRDSLTSISMGLVSVATTAGWKTLALFGYAAIYAYLAPWHL
PATRWYTWAIAILGVDLLYYAYHRIAHRVRLIWATHQAHHSSEYYNFATALRQKWNNSGEILMWLPLPLLGIPPWMVFFS
FSVNLIYQFWIHTERIDKLPRPFEFVFNTPSHHRVHHGMDKVYLDKNYGGILIVWDRLFGTFQAELFRPHYGLTKHVDTF
NVWTLQTRESVAIARDWRSASRLRDRLGYVFGPPGWAPRSAGRTAAGAPVVTSL

Sequences:

>Translated_294_residues
MRDPVLVAIPFFLLLLTLEWTAARKLEHLTARPAPGAHQTRDSLTSISMGLVSVATTAGWKTLALFGYAAIYAYLAPWHL
PATRWYTWAIAILGVDLLYYAYHRIAHRVRLIWATHQAHHSSEYYNFATALRQKWNNSGEILMWLPLPLLGIPPWMVFFS
FSVNLIYQFWIHTERIDKLPRPFEFVFNTPSHHRVHHGMDKVYLDKNYGGILIVWDRLFGTFQAELFRPHYGLTKHVDTF
NVWTLQTRESVAIARDWRSASRLRDRLGYVFGPPGWAPRSAGRTAAGAPVVTSL
>Mature_294_residues
MRDPVLVAIPFFLLLLTLEWTAARKLEHLTARPAPGAHQTRDSLTSISMGLVSVATTAGWKTLALFGYAAIYAYLAPWHL
PATRWYTWAIAILGVDLLYYAYHRIAHRVRLIWATHQAHHSSEYYNFATALRQKWNNSGEILMWLPLPLLGIPPWMVFFS
FSVNLIYQFWIHTERIDKLPRPFEFVFNTPSHHRVHHGMDKVYLDKNYGGILIVWDRLFGTFQAELFRPHYGLTKHVDTF
NVWTLQTRESVAIARDWRSASRLRDRLGYVFGPPGWAPRSAGRTAAGAPVVTSL

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=277, Percent_Identity=41.5162454873646, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI25144659, Length=258, Percent_Identity=35.6589147286822, Blast_Score=158, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 33856; Mature: 33856

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDPVLVAIPFFLLLLTLEWTAARKLEHLTARPAPGAHQTRDSLTSISMGLVSVATTAGW
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
KTLALFGYAAIYAYLAPWHLPATRWYTWAIAILGVDLLYYAYHRIAHRVRLIWATHQAHH
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHC
SSEYYNFATALRQKWNNSGEILMWLPLPLLGIPPWMVFFSFSVNLIYQFWIHTERIDKLP
CHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
RPFEFVFNTPSHHRVHHGMDKVYLDKNYGGILIVWDRLFGTFQAELFRPHYGLTKHVDTF
CCEEEEECCCCCCHHHCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCE
NVWTLQTRESVAIARDWRSASRLRDRLGYVFGPPGWAPRSAGRTAAGAPVVTSL
EEEEEECCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRDPVLVAIPFFLLLLTLEWTAARKLEHLTARPAPGAHQTRDSLTSISMGLVSVATTAGW
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
KTLALFGYAAIYAYLAPWHLPATRWYTWAIAILGVDLLYYAYHRIAHRVRLIWATHQAHH
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHC
SSEYYNFATALRQKWNNSGEILMWLPLPLLGIPPWMVFFSFSVNLIYQFWIHTERIDKLP
CHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
RPFEFVFNTPSHHRVHHGMDKVYLDKNYGGILIVWDRLFGTFQAELFRPHYGLTKHVDTF
CCEEEEECCCCCCHHHCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCE
NVWTLQTRESVAIARDWRSASRLRDRLGYVFGPPGWAPRSAGRTAAGAPVVTSL
EEEEEECCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]