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The map label for this gene is engA

Identifier: 41407513

GI number: 41407513

Start: 1527234

End: 1528634

Strand: Direct

Name: engA

Synonym: MAP1415

Alternate gene names: 41407513

Gene position: 1527234-1528634 (Clockwise)

Preceding gene: 41407512

Following gene: 41407517

Centisome position: 31.62

GC content: 72.23

Gene sequence:

>1401_bases
GTGACTCACGACGGAACATGGAGCGACGAAAGCGACTGGGAAGCGGTCGAATTCGAGCTCGACGAGGCGGCGCACGCGCC
CCCCGCGCCGGTGGTGGCGGTGGTGGGGCGGCCCAACGTCGGCAAGTCGACGCTGGTGAACCGGATCCTGGGCCGCCGGG
AGGCGGTGGTGCAGGACGTCCCTGGTGTCACCCGCGACCGGGTGTCCTACGACGCGCTGTGGACCGGGCGCCGATTCGTC
GTGCAGGACACCGGGGGATGGGAGCCCGACGCCAAGGGGCTGCAGCAGCTGGTCGCCGAACAGGCGTCGGTGGCCATGCG
CACCGCCGACGCGGTGATCCTGGTGGTCGACGCGCTCGTCGGCGCCACCACCGCCGACGAGGCCGCCGCCCGGATCCTGC
TGCGGTCCGGGAAGCCGGTCTTCTTGGCCGCCAACAAGGTTGACAGCGACAAGGCCGAGGCCGACGCGGCGATGCTGTGG
TCGCTGGGCCTCGGCGAGCCGCACCCGATCAGCGCGATGCACGGCCGCGGGGTGGCCGACCTGCTCGACGAGGTGCTGGC
CGCGCTGCCCGAGGTCTCCGAGGTGGCGCCCAGGCCCGGCGGGCCGCGGCGGGTGGCGCTGGTGGGCAAGCCGAACGTGG
GCAAGAGCTCGCTGTTGAACAAGCTGGCCGGCGATCAGCGCTCGGTGGTGCACGATGTGGCCGGGACGACGGTGGACCCG
GTGGACTCGCTGATCGAGCTGGGCGATCGGGTGTGGCGGTTCGTCGACACCGCGGGTCTGCGGCGCAAGGTGGGGCAGGC
CAGCGGCCACGAGTTCTATGCGTCGGTGCGCACGCACTCGGCCATCGACGCGGCCGAGGTGGTGATCGTGCTGATCGACG
CGTCGGCCCCGCTCACCGAGCAGGACCAGCGGGTGCTGTCCATGGTGATCGAAGCCGGCCGGGCCCTGGTGTTGGCGTTC
AACAAATGGGATCTGGTCGACGAGGACCGCCGCGAGCTGCTGGAGCGCGAGATCGACCGCGAGCTGGTGCAGCTGCGCTG
GGCGCAGCGGGTCAACATCTCCGCCAAGACCGGCCGCGCGGTGGCCAAGCTGGTGCCGGCGATGGAGACCGCCCTGGCGT
CGTGGGACACCCGGATCGCCACCGGCCCGCTGAACTCCTGGCTGAAGGAGGTGGTGGCGGCCACCCCGCCGCCGGTGCGG
GGCGGTAAGCAGCCGCGCATCCTGTTCGCCACCCAGGCCGCCGCCCGGCCGCCGACTTTCGTGCTGTTCACCACCGGCTT
TCTCGAGGCCGGATACCGGCGTTTCCTGGAGCGGCGCCTGCGCGAGGCGTTCGGGTTCGAGGGGACGCCGATCCGGATCA
ACGTGCGGGTGCGGGAGAAGCGCGGGGCCCGGCGGCGCTGA

Upstream 100 bases:

>100_bases
CGGCTCCCGACGCGGTGGTGGTCGACACCAGTGACATGACCGAGGCGCAGGTGATCGACCACCTGCGGGACCTGGTCAGA
CAGCGAAGCGAAGTGGCGCG

Downstream 100 bases:

>100_bases
GTGGCGTGGGCTGTGTCTGGAGGTATCGCGCTGTTCGAAATCCGCTAGCGCCGGTGCTGGCGTGTCTGCGGGTCGTCTCG
TAGTTCCCGGCGGTGCCTGG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTHDGTWSDESDWEAVEFELDEAAHAPPAPVVAVVGRPNVGKSTLVNRILGRREAVVQDVPGVTRDRVSYDALWTGRRFV
VQDTGGWEPDAKGLQQLVAEQASVAMRTADAVILVVDALVGATTADEAAARILLRSGKPVFLAANKVDSDKAEADAAMLW
SLGLGEPHPISAMHGRGVADLLDEVLAALPEVSEVAPRPGGPRRVALVGKPNVGKSSLLNKLAGDQRSVVHDVAGTTVDP
VDSLIELGDRVWRFVDTAGLRRKVGQASGHEFYASVRTHSAIDAAEVVIVLIDASAPLTEQDQRVLSMVIEAGRALVLAF
NKWDLVDEDRRELLEREIDRELVQLRWAQRVNISAKTGRAVAKLVPAMETALASWDTRIATGPLNSWLKEVVAATPPPVR
GGKQPRILFATQAAARPPTFVLFTTGFLEAGYRRFLERRLREAFGFEGTPIRINVRVREKRGARRR

Sequences:

>Translated_466_residues
MTHDGTWSDESDWEAVEFELDEAAHAPPAPVVAVVGRPNVGKSTLVNRILGRREAVVQDVPGVTRDRVSYDALWTGRRFV
VQDTGGWEPDAKGLQQLVAEQASVAMRTADAVILVVDALVGATTADEAAARILLRSGKPVFLAANKVDSDKAEADAAMLW
SLGLGEPHPISAMHGRGVADLLDEVLAALPEVSEVAPRPGGPRRVALVGKPNVGKSSLLNKLAGDQRSVVHDVAGTTVDP
VDSLIELGDRVWRFVDTAGLRRKVGQASGHEFYASVRTHSAIDAAEVVIVLIDASAPLTEQDQRVLSMVIEAGRALVLAF
NKWDLVDEDRRELLEREIDRELVQLRWAQRVNISAKTGRAVAKLVPAMETALASWDTRIATGPLNSWLKEVVAATPPPVR
GGKQPRILFATQAAARPPTFVLFTTGFLEAGYRRFLERRLREAFGFEGTPIRINVRVREKRGARRR
>Mature_465_residues
THDGTWSDESDWEAVEFELDEAAHAPPAPVVAVVGRPNVGKSTLVNRILGRREAVVQDVPGVTRDRVSYDALWTGRRFVV
QDTGGWEPDAKGLQQLVAEQASVAMRTADAVILVVDALVGATTADEAAARILLRSGKPVFLAANKVDSDKAEADAAMLWS
LGLGEPHPISAMHGRGVADLLDEVLAALPEVSEVAPRPGGPRRVALVGKPNVGKSSLLNKLAGDQRSVVHDVAGTTVDPV
DSLIELGDRVWRFVDTAGLRRKVGQASGHEFYASVRTHSAIDAAEVVIVLIDASAPLTEQDQRVLSMVIEAGRALVLAFN
KWDLVDEDRRELLEREIDRELVQLRWAQRVNISAKTGRAVAKLVPAMETALASWDTRIATGPLNSWLKEVVAATPPPVRG
GKQPRILFATQAAARPPTFVLFTTGFLEAGYRRFLERRLREAFGFEGTPIRINVRVREKRGARRR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=468, Percent_Identity=35.8974358974359, Blast_Score=274, Evalue=7e-75,
Organism=Escherichia coli, GI1788919, Length=180, Percent_Identity=32.2222222222222, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=127, Percent_Identity=33.8582677165354, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=206, Percent_Identity=26.2135922330097, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50703; Mature: 50572

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDGTWSDESDWEAVEFELDEAAHAPPAPVVAVVGRPNVGKSTLVNRILGRREAVVQDV
CCCCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
PGVTRDRVSYDALWTGRRFVVQDTGGWEPDAKGLQQLVAEQASVAMRTADAVILVVDALV
CCCCHHCCCHHEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GATTADEAAARILLRSGKPVFLAANKVDSDKAEADAAMLWSLGLGEPHPISAMHGRGVAD
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHCCCCHHH
LLDEVLAALPEVSEVAPRPGGPRRVALVGKPNVGKSSLLNKLAGDQRSVVHDVAGTTVDP
HHHHHHHHCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHCCCCCCH
VDSLIELGDRVWRFVDTAGLRRKVGQASGHEFYASVRTHSAIDAAEVVIVLIDASAPLTE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCH
QDQRVLSMVIEAGRALVLAFNKWDLVDEDRRELLEREIDRELVQLRWAQRVNISAKTGRA
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VAKLVPAMETALASWDTRIATGPLNSWLKEVVAATPPPVRGGKQPRILFATQAAARPPTF
HHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEE
VLFTTGFLEAGYRRFLERRLREAFGFEGTPIRINVRVREKRGARRR
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure 
THDGTWSDESDWEAVEFELDEAAHAPPAPVVAVVGRPNVGKSTLVNRILGRREAVVQDV
CCCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
PGVTRDRVSYDALWTGRRFVVQDTGGWEPDAKGLQQLVAEQASVAMRTADAVILVVDALV
CCCCHHCCCHHEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GATTADEAAARILLRSGKPVFLAANKVDSDKAEADAAMLWSLGLGEPHPISAMHGRGVAD
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHCCCCHHH
LLDEVLAALPEVSEVAPRPGGPRRVALVGKPNVGKSSLLNKLAGDQRSVVHDVAGTTVDP
HHHHHHHHCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHCCCCCCH
VDSLIELGDRVWRFVDTAGLRRKVGQASGHEFYASVRTHSAIDAAEVVIVLIDASAPLTE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCH
QDQRVLSMVIEAGRALVLAFNKWDLVDEDRRELLEREIDRELVQLRWAQRVNISAKTGRA
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VAKLVPAMETALASWDTRIATGPLNSWLKEVVAATPPPVRGGKQPRILFATQAAARPPTF
HHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEE
VLFTTGFLEAGYRRFLERRLREAFGFEGTPIRINVRVREKRGARRR
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA