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The map label for this gene is infC

Identifier: 41407450

GI number: 41407450

Start: 1454622

End: 1455176

Strand: Direct

Name: infC

Synonym: MAP1352

Alternate gene names: 41407450

Gene position: 1454622-1455176 (Clockwise)

Preceding gene: 41407443

Following gene: 41407451

Centisome position: 30.12

GC content: 64.68

Gene sequence:

>555_bases
TTGATCGGCCCAGGGGGAGAGCAGGTAGGCATAGTGCGCATCGAAGACGCACTGCGCGTCGCCGCGGACGCCGATCTCGA
CCTTGTCGAAGTCGCCCCGAACGCCAGACCACCGGTCTGCAAGATCATGGACTACGGCAAGTTCAAATACGAAGCGGCGC
AAAAGGCGCGCGAATCCCGCCGGAATCAGCAGCAGACCGTCGTCAAGGAACAAAAGCTGCGACCCAAGATCGACGATCAC
GACTACGAGACCAAAAAGGGTCACGTCATCCGCTTCCTGGAAGCGGGATCGAAGGTGAAGGTGACCATCATGTTCCGCGG
ACGTGAGCAGTCGCGGCCCGAGCTGGGCTACCGATTGCTGCAGCGGCTGGGCGCCGACGTCGCCGAATACGGTTTCGTCG
AGACGTCCGCCAAGCAGGACGGCCGCAACATGACGATGGTGCTGGCACCGCATCGCGGCGCGAAGACTCGCGCCAGGGCG
CGGCATCCCGAGGGGCCCGGCGGCGCGGCATCGGACTCCGATGCGGCCGCGGACGCCGAACCCTCGTCGAACTGA

Upstream 100 bases:

>100_bases
CACGCAGGATATTCGCCAGGACATATAGAAGCCCAACAAGGGAGGCCCCATCAGCACTGAGACCCGCGTCAACGAGCGCA
TCCGCGTACCTGAAGTCCGG

Downstream 100 bases:

>100_bases
CCCACCGCCCGACCACGACAGTCCTTACCGAACAGAGGAAACATGCCCAAAGCCAAGACCCACAGCGGGGCTTCAAAGCG
GTTCCGGCGCACCGGAACCG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKFKYEAAQKARESRRNQQQTVVKEQKLRPKIDDH
DYETKKGHVIRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVAEYGFVETSAKQDGRNMTMVLAPHRGAKTRARA
RHPEGPGGAASDSDAAADAEPSSN

Sequences:

>Translated_184_residues
MIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKFKYEAAQKARESRRNQQQTVVKEQKLRPKIDDH
DYETKKGHVIRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVAEYGFVETSAKQDGRNMTMVLAPHRGAKTRARA
RHPEGPGGAASDSDAAADAEPSSN
>Mature_184_residues
MIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKFKYEAAQKARESRRNQQQTVVKEQKLRPKIDDH
DYETKKGHVIRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVAEYGFVETSAKQDGRNMTMVLAPHRGAKTRARA
RHPEGPGGAASDSDAAADAEPSSN

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=153, Percent_Identity=47.7124183006536, Blast_Score=136, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20255; Mature: 20255

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKFKYEAAQKARESR
CCCCCCCEEEEEEEHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHH
RNQQQTVVKEQKLRPKIDDHDYETKKGHVIRFLEAGSKVKVTIMFRGREQSRPELGYRLL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHH
QRLGADVAEYGFVETSAKQDGRNMTMVLAPHRGAKTRARARHPEGPGGAASDSDAAADAE
HHHCCCHHHHCCEECCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
PSSN
CCCC
>Mature Secondary Structure
MIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKFKYEAAQKARESR
CCCCCCCEEEEEEEHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHH
RNQQQTVVKEQKLRPKIDDHDYETKKGHVIRFLEAGSKVKVTIMFRGREQSRPELGYRLL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHH
QRLGADVAEYGFVETSAKQDGRNMTMVLAPHRGAKTRARARHPEGPGGAASDSDAAADAE
HHHCCCHHHHCCEECCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
PSSN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]