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The map label for this gene is ileS

Identifier: 41407344

GI number: 41407344

Start: 1324371

End: 1327532

Strand: Direct

Name: ileS

Synonym: MAP1246

Alternate gene names: 41407344

Gene position: 1324371-1327532 (Clockwise)

Preceding gene: 41407343

Following gene: 41407345

Centisome position: 27.42

GC content: 68.28

Gene sequence:

>3162_bases
GTGACCGACAATCTCGGGTTCCAGGCTGACCGCGAGGCTCAGCCGGCGGATTCCGTCCAGACTTACCCGAAGCCGGCCGG
CGGCGCGCCCGACTTCCCGGCGCTCGAGCTCGAGGTGCTCGACTACTGGGCCCGCGACGACACCTTCCGGGCCAGCATCG
CCCGCCGCGACGGCGCCGAGGAATACGTGTTCTACGACGGGCCGCCGTTCGCCAACGGGCTGCCGCACTACGGCCACCTG
CTCACCGGCTACGTCAAGGACATCGTCCCGCGCTACCGCACCATGCGCGGCAACAAGGTGGAGCGCCGCTTCGGCTGGGA
CACCCATGGGCTGCCGGCCGAACTGGAAGTGGAACGCCAGTTGGGCATCACCGACAAATCGCAGATCGACGACATGGGCA
TCGCCGCGTTCAACGACGCCTGCCGCGAATCGGTGTTGCGCTACACCGACGAGTGGCGGGCCTATGTGACCCGCCAGGCC
CGCTGGGTCGATTTCGACCACGACTACAAGACGCTCGACCTGCCCTACATGGAGTCGGTGATCTGGGCGTTCAAGCAGCT
CTGGGACAAGGGCCTGGCCTACGAGGGCTACCGGGTGCTGCCGTACTGCTGGCGCGACGAAACCCCGCTGTCCAACCACG
AATTGCGGATGGACGACGACGTGTACCCGAGCCGGCAGGACCCGGCGCTGACGGTCGGGTTCAAGGTGGTGGGCGGCGAG
CTGGACGGCGCGCACCTGTTGATCTGGACGACGACGCCGTGGACGCTGCCGTCCAACCTGGCCGTCGCCGTCCACCCGGA
GGTGACCTATGTGCAGGTGCGCTCCGGTGACCGTCGTTTCGTGCTGGCCCAGCCGCGGCTGGCCGCCTACGCCCGCGAGC
TGGGCCCCGAACCCGAGATCCTGGGCAGCTACCGGGGCGCCGAGCTGCTGGGCACCCGGTACCTGCCGCCGTTCCCGTAT
TTCATGGACAACCCCAACGCATTTCGGGTGCTGGCCGGCGAGTTCGTCACCACCGAGGACGGTACCGGGATCGTGCACCT
GGCGCCGGCCTACGGCGAAGACGACATGGCCGTCGCCGACGCCGCGGGCATCGCCCCGGTCACGCCGGTCGACTCCAACG
GACGCTTCGACGCCGCCGTCCCGGATTACCAGGGACTCAACGTCTTCGACGCCAACCCGCAGATCATCTGGGACCTGAAG
AACGGCAGCGGCGCCGCCGCGGCCAACGCGCCGGTGCTGCTGCGCCACGAAACCTACGAGCACCCTTACCCGCACTGCTG
GCGCTGCCGCAACCCGCTGATCTATCGGGCGGTGTCGTCCTGGTTCGTGGCGGTCACCCGATTCCGGGACCGCATGGTCG
AACTCAACCAGCAGATCACCTGGTATCCCGAACACGTCAAGGACGGCCAGTTCGGCAAGTGGCTGGCCGGCGCCCGCGAC
TGGTCGATCTCACGAAACCGCTACTGGGGCACCCCGATTCCGGTGTGGAAGTCCGACGACCCGGCCTACCCGCGGATCGA
CGTGTACGGCAGCCTCGACGAACTCGAGCGCGACTTCGGGGTGCGGCCGGACAACCTGCACCGGCCCTACATCGACGAGC
TGACCCGGCCCAACCCCGACGACCCGAGCGGTCGCAGCACCATGCGCCGCATCCCCGACGTGCTCGACGTCTGGTTCGAC
TCGGGGTCCATGCCGTACGCGCAGGTCCACTACCCGTTCGAGAACCGCGACTGGTTCGAGACGCATTACCCCGGCGACTT
CATCGTCGAATACATCGGGCAGACCCGCGGCTGGTTCTACACCCTGCACGTGCTGGCCACCGCGCTGTTCGACCGGCCGG
CGTTCAAAACCTGTGTGGCCCATGGCATCGTGCTGGGCTCCGACGGACAGAAGATGAGCAAGTCGCTGCGCAACTACCCC
GACGTGTCGGAGGTGTTCGACCGCGACGGCTCCGATGCCATGCGCTGGTTCTTGATGGCCTCGCCGATCCTGCGCGGGGG
CAATCTAATCGTCACCGAACAGGGCATCCGCGACGGCGTGCGCCAGGTGCTGCTGCCGTTCTGGAACGCCTACAGCTTCC
TGGCCCTCTACGCGCCGAAAATCGGTACCTGGCGCACGGATTCGCCCCAGGTGCTGGACCGCTACATCCTGGCCAAATTA
GCCGAACTGCGCGACGACCTGACCCGGGAGATGGACGCCTGCGACATTTCGCGGGCCTGCGAGCAGCTGCGCCAGTTCAC
CGAGGCGCTGACGAATTGGTATGTGCGACGGTCGCGTTCGCGGTTCTGGAGCGAGGACGCCGACGCCATCGACACGCTGC
ACACCGTGCTGGAGGTGACCGCGCGGCTGGCCGCGCCGCTGCTGCCCTCGGTCACCGAGTTGGTCTGGCGCGGCCTGACC
GGTGGACGCTCGGTGCATCTGACCGACTGGCCGCGCAGCGGCGAGCTGCCCGCCGACCCCGGCCTGGTCGCGGCGATGGA
CCAGGTTCGCGAGGTGTGCTCGGCCGCCTCCTCGCTGCGTAAGGCAAAGAAGCTGCGGGTGCGCCTACCGCTGCCGAAAC
TGACTGTGGCGGTGGAGAATCCGCAACACCTGGCGCCGTTCGTCGACCTGATCGCCGACGAGCTCAACGTCAAGAGCGTC
GAGTTGACCGACGCGATCGACACCTACGGCACCTTCGAGCTGACCGTCAACGCCCGGGTGGCCGGGCCGCGGCTGGGCAA
GGACGTGCAGGCGGCCATCAAGGCCGTCAAGGCGGGGGAGGGCGTCGTCAACGCAGACGGCACCCTGACCGCAGGCCCGG
CCGTGCTGCGGCCCGAGGAGTACAGCTCACGGCTGGTGGCCGCCGACCCGGAATTCACCGCGGCCCTGCCGAATGGGGCC
GGCCTGGTGGTCCTCGACGGCACGGTCACCCCGGAGCTAGAGGCCGAGGGGTGGGCGAAGGACCGGATCCGCGAATTGCA
GGAGCTGCGCAAGTCGACCGGGCTGGACGTCTCCGACCGGATCAGCGTGGTGATGTCGGTGCCCGCCGGGCGGGCCGAGT
GGGCGCGCACCCACCGCGACCTGATCGCCGGTGAAATCCTGGCCACCCGTTTCGAATTCGGGGAGCCGGCCGACCCCGTC
GCGATCGGCGACGGCGTGCGGGTGAGCATTTCCAAAGTCTGA

Upstream 100 bases:

>100_bases
CCACGCGAAAGCGCGGCAAGCGGGGTGGTACCGCGGCGCTCGCGCAGCCAGCGCGTCGTCGTCCCCGGTTTGCACCGTGG
CACAGGAGACAACGCGCATC

Downstream 100 bases:

>100_bases
GCCGCGAAAGTGCAACTGGCGACGCATTTACCGAGTAACGGTGTCGGTAGATGCACTTTCGTCGGTTGTCGGAGCTGTGT
GGCAGCCTCCGCCCATGGGC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1053; Mature: 1052

Protein sequence:

>1053_residues
MTDNLGFQADREAQPADSVQTYPKPAGGAPDFPALELEVLDYWARDDTFRASIARRDGAEEYVFYDGPPFANGLPHYGHL
LTGYVKDIVPRYRTMRGNKVERRFGWDTHGLPAELEVERQLGITDKSQIDDMGIAAFNDACRESVLRYTDEWRAYVTRQA
RWVDFDHDYKTLDLPYMESVIWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYPSRQDPALTVGFKVVGGE
LDGAHLLIWTTTPWTLPSNLAVAVHPEVTYVQVRSGDRRFVLAQPRLAAYARELGPEPEILGSYRGAELLGTRYLPPFPY
FMDNPNAFRVLAGEFVTTEDGTGIVHLAPAYGEDDMAVADAAGIAPVTPVDSNGRFDAAVPDYQGLNVFDANPQIIWDLK
NGSGAAAANAPVLLRHETYEHPYPHCWRCRNPLIYRAVSSWFVAVTRFRDRMVELNQQITWYPEHVKDGQFGKWLAGARD
WSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDELERDFGVRPDNLHRPYIDELTRPNPDDPSGRSTMRRIPDVLDVWFD
SGSMPYAQVHYPFENRDWFETHYPGDFIVEYIGQTRGWFYTLHVLATALFDRPAFKTCVAHGIVLGSDGQKMSKSLRNYP
DVSEVFDRDGSDAMRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPFWNAYSFLALYAPKIGTWRTDSPQVLDRYILAKL
AELRDDLTREMDACDISRACEQLRQFTEALTNWYVRRSRSRFWSEDADAIDTLHTVLEVTARLAAPLLPSVTELVWRGLT
GGRSVHLTDWPRSGELPADPGLVAAMDQVREVCSAASSLRKAKKLRVRLPLPKLTVAVENPQHLAPFVDLIADELNVKSV
ELTDAIDTYGTFELTVNARVAGPRLGKDVQAAIKAVKAGEGVVNADGTLTAGPAVLRPEEYSSRLVAADPEFTAALPNGA
GLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVSDRISVVMSVPAGRAEWARTHRDLIAGEILATRFEFGEPADPV
AIGDGVRVSISKV

Sequences:

>Translated_1053_residues
MTDNLGFQADREAQPADSVQTYPKPAGGAPDFPALELEVLDYWARDDTFRASIARRDGAEEYVFYDGPPFANGLPHYGHL
LTGYVKDIVPRYRTMRGNKVERRFGWDTHGLPAELEVERQLGITDKSQIDDMGIAAFNDACRESVLRYTDEWRAYVTRQA
RWVDFDHDYKTLDLPYMESVIWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYPSRQDPALTVGFKVVGGE
LDGAHLLIWTTTPWTLPSNLAVAVHPEVTYVQVRSGDRRFVLAQPRLAAYARELGPEPEILGSYRGAELLGTRYLPPFPY
FMDNPNAFRVLAGEFVTTEDGTGIVHLAPAYGEDDMAVADAAGIAPVTPVDSNGRFDAAVPDYQGLNVFDANPQIIWDLK
NGSGAAAANAPVLLRHETYEHPYPHCWRCRNPLIYRAVSSWFVAVTRFRDRMVELNQQITWYPEHVKDGQFGKWLAGARD
WSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDELERDFGVRPDNLHRPYIDELTRPNPDDPSGRSTMRRIPDVLDVWFD
SGSMPYAQVHYPFENRDWFETHYPGDFIVEYIGQTRGWFYTLHVLATALFDRPAFKTCVAHGIVLGSDGQKMSKSLRNYP
DVSEVFDRDGSDAMRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPFWNAYSFLALYAPKIGTWRTDSPQVLDRYILAKL
AELRDDLTREMDACDISRACEQLRQFTEALTNWYVRRSRSRFWSEDADAIDTLHTVLEVTARLAAPLLPSVTELVWRGLT
GGRSVHLTDWPRSGELPADPGLVAAMDQVREVCSAASSLRKAKKLRVRLPLPKLTVAVENPQHLAPFVDLIADELNVKSV
ELTDAIDTYGTFELTVNARVAGPRLGKDVQAAIKAVKAGEGVVNADGTLTAGPAVLRPEEYSSRLVAADPEFTAALPNGA
GLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVSDRISVVMSVPAGRAEWARTHRDLIAGEILATRFEFGEPADPV
AIGDGVRVSISKV
>Mature_1052_residues
TDNLGFQADREAQPADSVQTYPKPAGGAPDFPALELEVLDYWARDDTFRASIARRDGAEEYVFYDGPPFANGLPHYGHLL
TGYVKDIVPRYRTMRGNKVERRFGWDTHGLPAELEVERQLGITDKSQIDDMGIAAFNDACRESVLRYTDEWRAYVTRQAR
WVDFDHDYKTLDLPYMESVIWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYPSRQDPALTVGFKVVGGEL
DGAHLLIWTTTPWTLPSNLAVAVHPEVTYVQVRSGDRRFVLAQPRLAAYARELGPEPEILGSYRGAELLGTRYLPPFPYF
MDNPNAFRVLAGEFVTTEDGTGIVHLAPAYGEDDMAVADAAGIAPVTPVDSNGRFDAAVPDYQGLNVFDANPQIIWDLKN
GSGAAAANAPVLLRHETYEHPYPHCWRCRNPLIYRAVSSWFVAVTRFRDRMVELNQQITWYPEHVKDGQFGKWLAGARDW
SISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDELERDFGVRPDNLHRPYIDELTRPNPDDPSGRSTMRRIPDVLDVWFDS
GSMPYAQVHYPFENRDWFETHYPGDFIVEYIGQTRGWFYTLHVLATALFDRPAFKTCVAHGIVLGSDGQKMSKSLRNYPD
VSEVFDRDGSDAMRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPFWNAYSFLALYAPKIGTWRTDSPQVLDRYILAKLA
ELRDDLTREMDACDISRACEQLRQFTEALTNWYVRRSRSRFWSEDADAIDTLHTVLEVTARLAAPLLPSVTELVWRGLTG
GRSVHLTDWPRSGELPADPGLVAAMDQVREVCSAASSLRKAKKLRVRLPLPKLTVAVENPQHLAPFVDLIADELNVKSVE
LTDAIDTYGTFELTVNARVAGPRLGKDVQAAIKAVKAGEGVVNADGTLTAGPAVLRPEEYSSRLVAADPEFTAALPNGAG
LVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVSDRISVVMSVPAGRAEWARTHRDLIAGEILATRFEFGEPADPVA
IGDGVRVSISKV

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1027, Percent_Identity=40.7984420642648, Blast_Score=731, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1027, Percent_Identity=40.7984420642648, Blast_Score=731, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=819, Percent_Identity=28.3272283272283, Blast_Score=291, Evalue=3e-78,
Organism=Homo sapiens, GI268370293, Length=884, Percent_Identity=24.2081447963801, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI268370297, Length=884, Percent_Identity=24.2081447963801, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI268370295, Length=855, Percent_Identity=24.4444444444444, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI5454158, Length=888, Percent_Identity=24.0990990990991, Blast_Score=147, Evalue=4e-35,
Organism=Escherichia coli, GI2367096, Length=821, Percent_Identity=28.5018270401949, Blast_Score=303, Evalue=5e-83,
Organism=Escherichia coli, GI1790708, Length=900, Percent_Identity=22.4444444444444, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1786861, Length=875, Percent_Identity=22.2857142857143, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17541896, Length=1029, Percent_Identity=38.7755102040816, Blast_Score=686, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=805, Percent_Identity=25.0931677018634, Blast_Score=215, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI72001587, Length=920, Percent_Identity=22.7173913043478, Blast_Score=149, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17510661, Length=811, Percent_Identity=21.8249075215783, Blast_Score=130, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1070, Percent_Identity=37.6635514018692, Blast_Score=694, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=895, Percent_Identity=23.463687150838, Blast_Score=210, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6321531, Length=794, Percent_Identity=23.4256926952141, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI28574730, Length=1034, Percent_Identity=39.7485493230174, Blast_Score=694, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1034, Percent_Identity=39.7485493230174, Blast_Score=694, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1034, Percent_Identity=39.7485493230174, Blast_Score=694, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=769, Percent_Identity=26.1378413524057, Blast_Score=229, Evalue=1e-59,
Organism=Drosophila melanogaster, GI21355675, Length=875, Percent_Identity=22.6285714285714, Blast_Score=144, Evalue=4e-34,
Organism=Drosophila melanogaster, GI17864482, Length=857, Percent_Identity=22.7537922987165, Blast_Score=141, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24653289, Length=857, Percent_Identity=22.7537922987165, Blast_Score=141, Evalue=3e-33,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_MYCPA (Q740U6)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_960180.1
- ProteinModelPortal:   Q740U6
- SMR:   Q740U6
- EnsemblBacteria:   EBMYCT00000036540
- GeneID:   2719583
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP1246
- NMPDR:   fig|262316.1.peg.1246
- GeneTree:   EBGT00050000015649
- HOGENOM:   HBG577712
- OMA:   DCHGLPA
- ProtClustDB:   PRK06039
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 118306; Mature: 118175

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 634-634

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNLGFQADREAQPADSVQTYPKPAGGAPDFPALELEVLDYWARDDTFRASIARRDGAE
CCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEHHHHHHCCCCHHHHHHHHCCCCC
EYVFYDGPPFANGLPHYGHLLTGYVKDIVPRYRTMRGNKVERRFGWDTHGLPAELEVERQ
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCEEEHHH
LGITDKSQIDDMGIAAFNDACRESVLRYTDEWRAYVTRQARWVDFDHDYKTLDLPYMESV
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCHHHHHH
IWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYPSRQDPALTVGFKVVGGE
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEECCCCCCCCCCCCEEEEEEEEECCC
LDGAHLLIWTTTPWTLPSNLAVAVHPEVTYVQVRSGDRRFVLAQPRLAAYARELGPEPEI
CCCCEEEEEECCCCCCCCCCEEEECCCEEEEEEECCCCEEEEECCHHHHHHHHHCCCHHH
LGSYRGAELLGTRYLPPFPYFMDNPNAFRVLAGEFVTTEDGTGIVHLAPAYGEDDMAVAD
HHCCCCHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCCHHH
AAGIAPVTPVDSNGRFDAAVPDYQGLNVFDANPQIIWDLKNGSGAAAANAPVLLRHETYE
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCC
HPYPHCWRCRNPLIYRAVSSWFVAVTRFRDRMVELNQQITWYPEHVKDGQFGKWLAGARD
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHCCCCCCCHHHCCCCC
WSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDELERDFGVRPDNLHRPYIDELTRPNPD
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCHHHHHCCCCCC
DPSGRSTMRRIPDVLDVWFDSGSMPYAQVHYPFENRDWFETHYPGDFIVEYIGQTRGWFY
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHH
TLHVLATALFDRPAFKTCVAHGIVLGSDGQKMSKSLRNYPDVSEVFDRDGSDAMRWFLMA
HHHHHHHHHHCCHHHHHHHHHCEEECCCCHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHH
SPILRGGNLIVTEQGIRDGVRQVLLPFWNAYSFLALYAPKIGTWRTDSPQVLDRYILAKL
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AELRDDLTREMDACDISRACEQLRQFTEALTNWYVRRSRSRFWSEDADAIDTLHTVLEVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ARLAAPLLPSVTELVWRGLTGGRSVHLTDWPRSGELPADPGLVAAMDQVREVCSAASSLR
HHHHHHCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KAKKLRVRLPLPKLTVAVENPQHLAPFVDLIADELNVKSVELTDAIDTYGTFELTVNARV
HHHHCEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEHHHHCCCCEEEEEEEEEE
AGPRLGKDVQAAIKAVKAGEGVVNADGTLTAGPAVLRPEEYSSRLVAADPEFTAALPNGA
CCCCCCHHHHHHHHHHHCCCCEECCCCCEECCCCEECCHHHCCCEEECCCCCEEECCCCC
GLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVSDRISVVMSVPAGRAEWARTHRD
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCEEEEEECCCCHHHHHHHHHH
LIAGEILATRFEFGEPADPVAIGDGVRVSISKV
HHHHHHHHHHHCCCCCCCCEEECCCCEEEEECC
>Mature Secondary Structure 
TDNLGFQADREAQPADSVQTYPKPAGGAPDFPALELEVLDYWARDDTFRASIARRDGAE
CCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEHHHHHHCCCCHHHHHHHHCCCCC
EYVFYDGPPFANGLPHYGHLLTGYVKDIVPRYRTMRGNKVERRFGWDTHGLPAELEVERQ
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCEEEHHH
LGITDKSQIDDMGIAAFNDACRESVLRYTDEWRAYVTRQARWVDFDHDYKTLDLPYMESV
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCHHHHHH
IWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYPSRQDPALTVGFKVVGGE
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEECCCCCCCCCCCCEEEEEEEEECCC
LDGAHLLIWTTTPWTLPSNLAVAVHPEVTYVQVRSGDRRFVLAQPRLAAYARELGPEPEI
CCCCEEEEEECCCCCCCCCCEEEECCCEEEEEEECCCCEEEEECCHHHHHHHHHCCCHHH
LGSYRGAELLGTRYLPPFPYFMDNPNAFRVLAGEFVTTEDGTGIVHLAPAYGEDDMAVAD
HHCCCCHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCCHHH
AAGIAPVTPVDSNGRFDAAVPDYQGLNVFDANPQIIWDLKNGSGAAAANAPVLLRHETYE
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCC
HPYPHCWRCRNPLIYRAVSSWFVAVTRFRDRMVELNQQITWYPEHVKDGQFGKWLAGARD
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHCCCCCCCHHHCCCCC
WSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDELERDFGVRPDNLHRPYIDELTRPNPD
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCHHHHHCCCCCC
DPSGRSTMRRIPDVLDVWFDSGSMPYAQVHYPFENRDWFETHYPGDFIVEYIGQTRGWFY
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHH
TLHVLATALFDRPAFKTCVAHGIVLGSDGQKMSKSLRNYPDVSEVFDRDGSDAMRWFLMA
HHHHHHHHHHCCHHHHHHHHHCEEECCCCHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHH
SPILRGGNLIVTEQGIRDGVRQVLLPFWNAYSFLALYAPKIGTWRTDSPQVLDRYILAKL
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AELRDDLTREMDACDISRACEQLRQFTEALTNWYVRRSRSRFWSEDADAIDTLHTVLEVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ARLAAPLLPSVTELVWRGLTGGRSVHLTDWPRSGELPADPGLVAAMDQVREVCSAASSLR
HHHHHHCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KAKKLRVRLPLPKLTVAVENPQHLAPFVDLIADELNVKSVELTDAIDTYGTFELTVNARV
HHHHCEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEHHHHCCCCEEEEEEEEEE
AGPRLGKDVQAAIKAVKAGEGVVNADGTLTAGPAVLRPEEYSSRLVAADPEFTAALPNGA
CCCCCCHHHHHHHHHHHCCCCEECCCCCEECCCCEECCHHHCCCEEECCCCCEEECCCCC
GLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVSDRISVVMSVPAGRAEWARTHRD
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCEEEEEECCCCHHHHHHHHHH
LIAGEILATRFEFGEPADPVAIGDGVRVSISKV
HHHHHHHHHHHCCCCCCCCEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA