Click here to switch to the map view.

The map label for this gene is pcoS [H]

Identifier: 41407320

GI number: 41407320

Start: 1279708

End: 1281150

Strand: Direct

Name: pcoS [H]

Synonym: MAP1222

Alternate gene names: 41407320

Gene position: 1279708-1281150 (Clockwise)

Preceding gene: 41407319

Following gene: 41407323

Centisome position: 26.5

GC content: 75.26

Gene sequence:

>1443_bases
ATGACGCCGACGCCGTCGCTGCAACGCCGGGTGACGCTGGTGGTGCTGGCGCTGTTGACCGTGCTGCTGGTGGTGCTCGG
CGTCACCATCGACGTCACGATGGGCGTGCTCGCCCGCCGCAACCTGCACGACCGGCTGCTCGCCGCGACGTCGCGGGCCG
ACGCGCTGAGCGCCGCGCACACCGCCCCCGACCTGCTCGCCGCCGAGCTCAACGGCGGCGGGATCCGCGCGCTCGTCGTC
ACCGCGGACGGCCAGGCCTACGGGGACCGCGCGATCAGCCCCGACCTGGCCGAGGGGCCGGTCGAACCGCCCCCGCCGTA
CCCGCCGCCGTTACCGCCGCCGGCCTACCCGCCGCCGTACCCACCGCCCTATCCGCCCCCGCCCGGCCCGCCGCCGGATA
CGACTGCGACGGCCGTCGTGCACCCGTTGCCCGACGGCGCGCGGCTGATCCTGGTCGCCGACACCACGCAAACCACTCAG
GTCACCCGGCAACTGCGGGGTCTGATGATCGCCGCCGGCATCGTGACCCTGCTGATCGCGGCGCTGCTGTTGATCGCGGT
CAGCCGGGCGGCCCTGCGCCCGCTGGACCGGCTCACCGCGCTGGCCAACGCCATCACCACCGGGGACCGCGGCCGCCGGT
TGCGCCCGCACCGCGCCGACACCGAATTAGGCCGCGCCGCAAGCGCTTTCGACACGATGCTGGACGCCCTGGAGATGTCG
GAACGCCGGGCCCAACAGGCCGCCCAGGCCGCCCAGCGCGCCGAGACGGCGACCCGGCGCTTCCTCGTCGACGCCGCCCA
CGAGCTGCGCACCCCGATCGCCGGCATGCAGGTCGCCGCCGAGCAACTCGCGCACGGCGCCTCCGAACACCCCGACGACG
GGCAATACCGTCGGGCGGGCCTGCTGCTCTCCGACGCGCGCCGCGCCGGGCGACTCGTCAACGACATGCTGGACCTGAGC
CGCATCGACGCCGGGCTTCCGCTGGAACTGCACGACGTCGACGTGGCCGCCGTGCTGCGCGACGAAGCCGACCGGGCGGC
CCTGCTGGCACCCCAAATCGGCGTGCGCCGCACGGGACTCACCGCGCTGAACGTCCGGGCCGACGCCACCCGGCTGTCGC
AGATCGTGTCCAACCTGCTCGACAACGCTCGCCGCTACACCCCGCCCGGCGGCGCCATCGAGATCGACCTGCGCGCCGGC
GACGGCGCCGCCGAGATCACCGTCACCGACACCGGCCCGGGCATCCCGGACGACGAGCGGGAGCGCATTTTCGACCGGCT
GGTGCGCCTGGATGCCGGCCGCGCCCGCGACCACGGCGGCGCCGGGCTGGGCCTGGCCATCGCCCGGGCGCTGGCCCGCG
CGCACGGCGGCGACCTGGTGTGCCTGCCGCATCGGGGCGGTGCCCGGTTCCGGCTCACATTGCCGCGGGCGACCACACAG
TGA

Upstream 100 bases:

>100_bases
AGGTTCACGTCAGCGGGCTGCGGCGCAAGCTCGAGGCACACGGCCCGCGGATCCTGCACACCGTCCGCGGCATCGGCTAC
CGCCTACAACCCGAGCGGTC

Downstream 100 bases:

>100_bases
ACGGTGGCCGCCTCGAATACTCGAGGCGGCCACCCGTCGACGCATCACCAGCCCGGCGGTGGCGGAGGCCCGCCCGGCCC
GCCCGGTGGCGGGCCCAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTPTPSLQRRVTLVVLALLTVLLVVLGVTIDVTMGVLARRNLHDRLLAATSRADALSAAHTAPDLLAAELNGGGIRALVV
TADGQAYGDRAISPDLAEGPVEPPPPYPPPLPPPAYPPPYPPPYPPPPGPPPDTTATAVVHPLPDGARLILVADTTQTTQ
VTRQLRGLMIAAGIVTLLIAALLLIAVSRAALRPLDRLTALANAITTGDRGRRLRPHRADTELGRAASAFDTMLDALEMS
ERRAQQAAQAAQRAETATRRFLVDAAHELRTPIAGMQVAAEQLAHGASEHPDDGQYRRAGLLLSDARRAGRLVNDMLDLS
RIDAGLPLELHDVDVAAVLRDEADRAALLAPQIGVRRTGLTALNVRADATRLSQIVSNLLDNARRYTPPGGAIEIDLRAG
DGAAEITVTDTGPGIPDDERERIFDRLVRLDAGRARDHGGAGLGLAIARALARAHGGDLVCLPHRGGARFRLTLPRATTQ

Sequences:

>Translated_480_residues
MTPTPSLQRRVTLVVLALLTVLLVVLGVTIDVTMGVLARRNLHDRLLAATSRADALSAAHTAPDLLAAELNGGGIRALVV
TADGQAYGDRAISPDLAEGPVEPPPPYPPPLPPPAYPPPYPPPYPPPPGPPPDTTATAVVHPLPDGARLILVADTTQTTQ
VTRQLRGLMIAAGIVTLLIAALLLIAVSRAALRPLDRLTALANAITTGDRGRRLRPHRADTELGRAASAFDTMLDALEMS
ERRAQQAAQAAQRAETATRRFLVDAAHELRTPIAGMQVAAEQLAHGASEHPDDGQYRRAGLLLSDARRAGRLVNDMLDLS
RIDAGLPLELHDVDVAAVLRDEADRAALLAPQIGVRRTGLTALNVRADATRLSQIVSNLLDNARRYTPPGGAIEIDLRAG
DGAAEITVTDTGPGIPDDERERIFDRLVRLDAGRARDHGGAGLGLAIARALARAHGGDLVCLPHRGGARFRLTLPRATTQ
>Mature_479_residues
TPTPSLQRRVTLVVLALLTVLLVVLGVTIDVTMGVLARRNLHDRLLAATSRADALSAAHTAPDLLAAELNGGGIRALVVT
ADGQAYGDRAISPDLAEGPVEPPPPYPPPLPPPAYPPPYPPPYPPPPGPPPDTTATAVVHPLPDGARLILVADTTQTTQV
TRQLRGLMIAAGIVTLLIAALLLIAVSRAALRPLDRLTALANAITTGDRGRRLRPHRADTELGRAASAFDTMLDALEMSE
RRAQQAAQAAQRAETATRRFLVDAAHELRTPIAGMQVAAEQLAHGASEHPDDGQYRRAGLLLSDARRAGRLVNDMLDLSR
IDAGLPLELHDVDVAAVLRDEADRAALLAPQIGVRRTGLTALNVRADATRLSQIVSNLLDNARRYTPPGGAIEIDLRAGD
GAAEITVTDTGPGIPDDERERIFDRLVRLDAGRARDHGGAGLGLAIARALARAHGGDLVCLPHRGGARFRLTLPRATTQ

Specific function: Probable member of a two-component regulatory system pcoS/pcoR. May activate pcoR by phosphorylation [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=316, Percent_Identity=29.4303797468354, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788393, Length=292, Percent_Identity=29.4520547945205, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790861, Length=359, Percent_Identity=29.5264623955432, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=33.0396475770925, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789149, Length=298, Percent_Identity=28.5234899328859, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI48994928, Length=251, Percent_Identity=30.6772908366534, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=31.7269076305221, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790346, Length=313, Percent_Identity=28.1150159744409, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787894, Length=319, Percent_Identity=31.0344827586207, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788713, Length=259, Percent_Identity=27.027027027027, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=31.3008130081301, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790551, Length=212, Percent_Identity=31.6037735849057, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788279, Length=308, Percent_Identity=25.6493506493506, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=28.0172413793103, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1789403, Length=209, Percent_Identity=35.8851674641148, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=217, Percent_Identity=29.0322580645161, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=29.2237442922374, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787374, Length=367, Percent_Identity=26.158038147139, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR006290
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50784; Mature: 50653

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTPSLQRRVTLVVLALLTVLLVVLGVTIDVTMGVLARRNLHDRLLAATSRADALSAAH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TAPDLLAAELNGGGIRALVVTADGQAYGDRAISPDLAEGPVEPPPPYPPPLPPPAYPPPY
CCHHHHEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPPYPPPPGPPPDTTATAVVHPLPDGARLILVADTTQTTQVTRQLRGLMIAAGIVTLLIA
CCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ALLLIAVSRAALRPLDRLTALANAITTGDRGRRLRPHRADTELGRAASAFDTMLDALEMS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ERRAQQAAQAAQRAETATRRFLVDAAHELRTPIAGMQVAAEQLAHGASEHPDDGQYRRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHH
LLLSDARRAGRLVNDMLDLSRIDAGLPLELHDVDVAAVLRDEADRAALLAPQIGVRRTGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCCCEEECCCCCCCCCCC
TALNVRADATRLSQIVSNLLDNARRYTPPGGAIEIDLRAGDGAAEITVTDTGPGIPDDER
EEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHH
ERIFDRLVRLDAGRARDHGGAGLGLAIARALARAHGGDLVCLPHRGGARFRLTLPRATTQ
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCC
>Mature Secondary Structure 
TPTPSLQRRVTLVVLALLTVLLVVLGVTIDVTMGVLARRNLHDRLLAATSRADALSAAH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TAPDLLAAELNGGGIRALVVTADGQAYGDRAISPDLAEGPVEPPPPYPPPLPPPAYPPPY
CCHHHHEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPPYPPPPGPPPDTTATAVVHPLPDGARLILVADTTQTTQVTRQLRGLMIAAGIVTLLIA
CCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ALLLIAVSRAALRPLDRLTALANAITTGDRGRRLRPHRADTELGRAASAFDTMLDALEMS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ERRAQQAAQAAQRAETATRRFLVDAAHELRTPIAGMQVAAEQLAHGASEHPDDGQYRRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHH
LLLSDARRAGRLVNDMLDLSRIDAGLPLELHDVDVAAVLRDEADRAALLAPQIGVRRTGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCCCEEECCCCCCCCCCC
TALNVRADATRLSQIVSNLLDNARRYTPPGGAIEIDLRAGDGAAEITVTDTGPGIPDDER
EEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHH
ERIFDRLVRLDAGRARDHGGAGLGLAIARALARAHGGDLVCLPHRGGARFRLTLPRATTQ
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8594334 [H]