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The map label for this gene is fprB

Identifier: 41406923

GI number: 41406923

Start: 841517

End: 843217

Strand: Direct

Name: fprB

Synonym: MAP0825

Alternate gene names: 41406923

Gene position: 841517-843217 (Clockwise)

Preceding gene: 41406922

Following gene: 41406926

Centisome position: 17.42

GC content: 71.6

Gene sequence:

>1701_bases
ATGCCGCACGTTATTACCCAGTCGTGCTGTAACGACGGGTCCTGTGTTTTCGCGTGCCCGGTGAACTGCATTCACCCCAC
GCCCGACGAGCCCGGCTTCGCCACCTCGGAGATGCTCTACATCGACCCGGCGGCGTGCGTGGACTGCGGCGCCTGCGTCA
GCGCCTGCCCCGTCGGTGCGATCGCCCCCGACAACCGGCTGGACGACAAACAGCTGCCCTTCGTCGAGATCAACGCGTCG
TTCTACCCGAAACGGCCGGCCGGCCAGAAACTGCCGCCGACGTCCAAGCTGGCGCCGGTGATCCCGGCCGTCCCGGTGCG
GCCGCGCGGCCGGCCGCTGACGGTGGCCATCGTCGGATCCGGCCCGGCGGCGATGTACGCCGCCGACGAACTGCTCACCC
AGGACGGCGTGCGCGTCAACGTCTTCGAGAAGCTGCCGACGCCCTATGGGCTGGTGCGCGCCGGGGTGGCGCCCGATCAC
CAGAACACCAAGAAGGTGACCCGGCTCTTCGATCGGGTCGCCGGTCATGACCGCTTCCGGTTCTACCTCAACGTCGAGGT
CGGCAAGCATCTCAGCCACGCCGATCTGCTGGCCCATCATCACGCCGTGCTGTACGCGGTGGGGGCGCCCGACGACCGCC
GGCTCGACATCGAGGGCATGGGGCTGGCGGGCAGCGGAACCGCGACCGAGCTGGTGGCGTGGATCAACGGGCATCCCGAG
TTCACCGCGCTGCCAGTCGATCTGCGCCACGAGCGGGTGGTGATCATCGGCAACGGCAACGTCGCGCTCGACGTCGCCCG
GGTGCTCACCGCGGACCCCGATGACCTGGCCCGCACCGATATCGCCGACCACGCGCTGGCGGCACTGCGCGGCTCGGCGG
TGCGCGAGGTGGTGATCGCCGCCCGGCGCGGGCCGGCCCAGTCGGCGTTCACGCTGCCGGAACTGATCGGGCTCACCGGC
AGCCGCGAGGTGGTGCTCAGCGCGGCCGACCGCGAGCTGGTCGCCGCCGACCTGGCGAACGCCTCGGATGCCCTGACCAA
GGCCAAGCTGGAGGTTTTGAGCACGCTCGGCGACGCTGCGGCGCCCAGCGAGCGTCCGAGAATCAGGCTGGCGTATCGGC
TCACCCCCGACCGGATCCTCGGCGAGCAACGCGTCACCGGTGTGCAGTTCACGCTCACCGGCACCGACGAGACACGGTGC
CTGCCAACGGGTTTGGTGCTGACGTCGATCGGCTACCGCGGCAAGCCGATTCGCGACCTGCCCTACGACGAGGCGGCGGC
GGTGGTGCCCAACGACGGCGGCCGCGTCGTCGACCCCGCCTCGGGACGACCGGTGCCCGGCGCCTACGTCGCCGGCTGGA
TCAAGCGGGGACCCAGCGGGTTCATCGGTACCAACAAGTCCTGCTCGCTGCAGACCGTGCAGGCCCTGGTGGCCGATTTC
AACGCCGGCGAGCTGGCCGACCCGGCGGCCAAACCCGAGGCGCTGACCGCCCTGGTGCGTGCCCGCCGGCCCGACGCGAT
CGACGCGGCGGGGTGGCGAGCCATCGACGCCGCCGAAATCGCGCGCGGCAGCCAGGACGGCCGACCGCGCAACAAGTTCA
CCGACATCGGCGACATGCTGGCCGCCGCGGCCGCCGCAGAGCCGGCGCCGCCGCCGCGACGCCGGCTCCTGGCCCGGTTG
GTGCCGTCCGGGCGCGGCTAG

Upstream 100 bases:

>100_bases
GGCTGTGCAAGATCAACGGCAAGCCGTCGCGCTACCGCAGTGAACCGCAGCGGCAGCACCTGGCTGCCGTGCCGGCCGCC
TAACCACGGCGAGTTCCTTT

Downstream 100 bases:

>100_bases
GCCTGCCCGGCCCCCTGCTCAGCGGCCATCGCCGCCATCGCCGCCGCCATCTCCTCCGGGCTGACCTCGCGCACCGGCTG
CCCCAGGGACCAGTGGTGGC

Product: FprB

Products: NA

Alternate protein names: FNR [H]

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MPHVITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPAACVDCGACVSACPVGAIAPDNRLDDKQLPFVEINAS
FYPKRPAGQKLPPTSKLAPVIPAVPVRPRGRPLTVAIVGSGPAAMYAADELLTQDGVRVNVFEKLPTPYGLVRAGVAPDH
QNTKKVTRLFDRVAGHDRFRFYLNVEVGKHLSHADLLAHHHAVLYAVGAPDDRRLDIEGMGLAGSGTATELVAWINGHPE
FTALPVDLRHERVVIIGNGNVALDVARVLTADPDDLARTDIADHALAALRGSAVREVVIAARRGPAQSAFTLPELIGLTG
SREVVLSAADRELVAADLANASDALTKAKLEVLSTLGDAAAPSERPRIRLAYRLTPDRILGEQRVTGVQFTLTGTDETRC
LPTGLVLTSIGYRGKPIRDLPYDEAAAVVPNDGGRVVDPASGRPVPGAYVAGWIKRGPSGFIGTNKSCSLQTVQALVADF
NAGELADPAAKPEALTALVRARRPDAIDAAGWRAIDAAEIARGSQDGRPRNKFTDIGDMLAAAAAAEPAPPPRRRLLARL
VPSGRG

Sequences:

>Translated_566_residues
MPHVITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPAACVDCGACVSACPVGAIAPDNRLDDKQLPFVEINAS
FYPKRPAGQKLPPTSKLAPVIPAVPVRPRGRPLTVAIVGSGPAAMYAADELLTQDGVRVNVFEKLPTPYGLVRAGVAPDH
QNTKKVTRLFDRVAGHDRFRFYLNVEVGKHLSHADLLAHHHAVLYAVGAPDDRRLDIEGMGLAGSGTATELVAWINGHPE
FTALPVDLRHERVVIIGNGNVALDVARVLTADPDDLARTDIADHALAALRGSAVREVVIAARRGPAQSAFTLPELIGLTG
SREVVLSAADRELVAADLANASDALTKAKLEVLSTLGDAAAPSERPRIRLAYRLTPDRILGEQRVTGVQFTLTGTDETRC
LPTGLVLTSIGYRGKPIRDLPYDEAAAVVPNDGGRVVDPASGRPVPGAYVAGWIKRGPSGFIGTNKSCSLQTVQALVADF
NAGELADPAAKPEALTALVRARRPDAIDAAGWRAIDAAEIARGSQDGRPRNKFTDIGDMLAAAAAAEPAPPPRRRLLARL
VPSGRG
>Mature_565_residues
PHVITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPAACVDCGACVSACPVGAIAPDNRLDDKQLPFVEINASF
YPKRPAGQKLPPTSKLAPVIPAVPVRPRGRPLTVAIVGSGPAAMYAADELLTQDGVRVNVFEKLPTPYGLVRAGVAPDHQ
NTKKVTRLFDRVAGHDRFRFYLNVEVGKHLSHADLLAHHHAVLYAVGAPDDRRLDIEGMGLAGSGTATELVAWINGHPEF
TALPVDLRHERVVIIGNGNVALDVARVLTADPDDLARTDIADHALAALRGSAVREVVIAARRGPAQSAFTLPELIGLTGS
REVVLSAADRELVAADLANASDALTKAKLEVLSTLGDAAAPSERPRIRLAYRLTPDRILGEQRVTGVQFTLTGTDETRCL
PTGLVLTSIGYRGKPIRDLPYDEAAAVVPNDGGRVVDPASGRPVPGAYVAGWIKRGPSGFIGTNKSCSLQTVQALVADFN
AGELADPAAKPEALTALVRARRPDAIDAAGWRAIDAAEIARGSQDGRPRNKFTDIGDMLAAAAAAEPAPPPRRRLLARLV
PSGRG

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=453, Percent_Identity=39.2935982339956, Blast_Score=273, Evalue=3e-73,
Organism=Homo sapiens, GI111118983, Length=459, Percent_Identity=38.7799564270153, Blast_Score=266, Evalue=3e-71,
Organism=Escherichia coli, GI87082180, Length=165, Percent_Identity=29.6969696969697, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789606, Length=158, Percent_Identity=32.2784810126582, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17543860, Length=440, Percent_Identity=32.5, Blast_Score=202, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6320584, Length=485, Percent_Identity=28.659793814433, Blast_Score=160, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6320030, Length=262, Percent_Identity=25.9541984732824, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17137178, Length=460, Percent_Identity=35.4347826086957, Blast_Score=228, Evalue=7e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 59798; Mature: 59667

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHVITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPAACVDCGACVSACPVGA
CCCCCCHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCC
IAPDNRLDDKQLPFVEINASFYPKRPAGQKLPPTSKLAPVIPAVPVRPRGRPLTVAIVGS
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
GPAAMYAADELLTQDGVRVNVFEKLPTPYGLVRAGVAPDHQNTKKVTRLFDRVAGHDRFR
CCHHHHHHHHHHHCCCCEEEEHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEE
FYLNVEVGKHLSHADLLAHHHAVLYAVGAPDDRRLDIEGMGLAGSGTATELVAWINGHPE
EEEEEECCCCCCHHHHHHHCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHEEEECCCCC
FTALPVDLRHERVVIIGNGNVALDVARVLTADPDDLARTDIADHALAALRGSAVREVVIA
EEEEEEECCCCEEEEEECCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRGPAQSAFTLPELIGLTGSREVVLSAADRELVAADLANASDALTKAKLEVLSTLGDAA
HCCCCCCCHHCCHHHHCCCCCCEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
APSERPRIRLAYRLTPDRILGEQRVTGVQFTLTGTDETRCLPTGLVLTSIGYRGKPIRDL
CCCCCCEEEEEEEECHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCC
PYDEAAAVVPNDGGRVVDPASGRPVPGAYVAGWIKRGPSGFIGTNKSCSLQTVQALVADF
CCCCCEEEEECCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
NAGELADPAAKPEALTALVRARRPDAIDAAGWRAIDAAEIARGSQDGRPRNKFTDIGDML
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHH
AAAAAAEPAPPPRRRLLARLVPSGRG
HHHHCCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PHVITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPAACVDCGACVSACPVGA
CCCCCHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCC
IAPDNRLDDKQLPFVEINASFYPKRPAGQKLPPTSKLAPVIPAVPVRPRGRPLTVAIVGS
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
GPAAMYAADELLTQDGVRVNVFEKLPTPYGLVRAGVAPDHQNTKKVTRLFDRVAGHDRFR
CCHHHHHHHHHHHCCCCEEEEHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEE
FYLNVEVGKHLSHADLLAHHHAVLYAVGAPDDRRLDIEGMGLAGSGTATELVAWINGHPE
EEEEEECCCCCCHHHHHHHCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHEEEECCCCC
FTALPVDLRHERVVIIGNGNVALDVARVLTADPDDLARTDIADHALAALRGSAVREVVIA
EEEEEEECCCCEEEEEECCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRGPAQSAFTLPELIGLTGSREVVLSAADRELVAADLANASDALTKAKLEVLSTLGDAA
HCCCCCCCHHCCHHHHCCCCCCEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
APSERPRIRLAYRLTPDRILGEQRVTGVQFTLTGTDETRCLPTGLVLTSIGYRGKPIRDL
CCCCCCEEEEEEEECHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCC
PYDEAAAVVPNDGGRVVDPASGRPVPGAYVAGWIKRGPSGFIGTNKSCSLQTVQALVADF
CCCCCEEEEECCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
NAGELADPAAKPEALTALVRARRPDAIDAAGWRAIDAAEIARGSQDGRPRNKFTDIGDML
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHH
AAAAAAEPAPPPRRRLLARLVPSGRG
HHHHCCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]