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The map label for this gene is moaC

Identifier: 41406900

GI number: 41406900

Start: 823328

End: 823858

Strand: Direct

Name: moaC

Synonym: MAP0802

Alternate gene names: 41406900

Gene position: 823328-823858 (Clockwise)

Preceding gene: 41406899

Following gene: 41406901

Centisome position: 17.05

GC content: 71.75

Gene sequence:

>531_bases
ATGGCCAGGGCCCCTGAGGCCTCGACAGCCTCGGCGACCCGGGCGTCGGGAGAACCCCGCTCGGGTGCCCTGTCACACCT
GGACGAGCGGGGGGCCGCGCACATGGTCGACGTCAGCGGGAAGGCGCCCAGCAAGCGCACCGCCGTCGCCGCCGGGGTGC
TGCGCACCTCGGCGGACGTGGTGGCGCTGATCTCGACCGGCGGGCTGCCCAAGGGTGACGCGCTGGCCACCGCGCGGGTG
GCGGGCATCCAGGCCGCCAAGCGCACCAGCGACCTGATCCCGCTGTGCCATCAGCTGGCGCTCACCGGGGTCGACGTCGA
CTTCGCCGTGGGCGAGTCGGACATCGAGATCACCGCGACGGTGGCCAGCACCGACCGCACCGGCGTGGAGATGGAGGCGC
TGACCGCGGTCAGCGTGGCGGGCCTGACGCTCTACGACATGATCAAAGCGGTCGACCCGGCCGCGCGCATCGACGACGTT
CGAGTGCTCCGCAAGGAAGGCGGCAAAACCGGAATGTGGACACGGTCATGA

Upstream 100 bases:

>100_bases
CCGGCGCGCTGTCGCCGTTCGGCGAGCTGGTGTTCCCGCTGCCCGCCACCGAGCTGCCCTACCTGCACCCGGTCACCGTC
GTCAATCGGTAGGTCGCCGG

Downstream 100 bases:

>100_bases
CCACCCGATCGGCCCGCGTCATCATCGCCTCCACGCGTGCGTCGTCCGGAGAGTACGAGGACCGCTGCGGGCCGATCATC
ACCGAATGGCTTGCCCAGCA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MARAPEASTASATRASGEPRSGALSHLDERGAAHMVDVSGKAPSKRTAVAAGVLRTSADVVALISTGGLPKGDALATARV
AGIQAAKRTSDLIPLCHQLALTGVDVDFAVGESDIEITATVASTDRTGVEMEALTAVSVAGLTLYDMIKAVDPAARIDDV
RVLRKEGGKTGMWTRS

Sequences:

>Translated_176_residues
MARAPEASTASATRASGEPRSGALSHLDERGAAHMVDVSGKAPSKRTAVAAGVLRTSADVVALISTGGLPKGDALATARV
AGIQAAKRTSDLIPLCHQLALTGVDVDFAVGESDIEITATVASTDRTGVEMEALTAVSVAGLTLYDMIKAVDPAARIDDV
RVLRKEGGKTGMWTRS
>Mature_175_residues
ARAPEASTASATRASGEPRSGALSHLDERGAAHMVDVSGKAPSKRTAVAAGVLRTSADVVALISTGGLPKGDALATARVA
GIQAAKRTSDLIPLCHQLALTGVDVDFAVGESDIEITATVASTDRTGVEMEALTAVSVAGLTLYDMIKAVDPAARIDDVR
VLRKEGGKTGMWTRS

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=150, Percent_Identity=51.3333333333333, Blast_Score=136, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=42.9530201342282, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28574490, Length=148, Percent_Identity=47.2972972972973, Blast_Score=126, Evalue=7e-30,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=47.4452554744526, Blast_Score=116, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17996; Mature: 17864

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARAPEASTASATRASGEPRSGALSHLDERGAAHMVDVSGKAPSKRTAVAAGVLRTSADV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCE
VALISTGGLPKGDALATARVAGIQAAKRTSDLIPLCHQLALTGVDVDFAVGESDIEITAT
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEE
VASTDRTGVEMEALTAVSVAGLTLYDMIKAVDPAARIDDVRVLRKEGGKTGMWTRS
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ARAPEASTASATRASGEPRSGALSHLDERGAAHMVDVSGKAPSKRTAVAAGVLRTSADV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCE
VALISTGGLPKGDALATARVAGIQAAKRTSDLIPLCHQLALTGVDVDFAVGESDIEITAT
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEE
VASTDRTGVEMEALTAVSVAGLTLYDMIKAVDPAARIDDVRVLRKEGGKTGMWTRS
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]