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The map label for this gene is frc [H]

Identifier: 41406854

GI number: 41406854

Start: 778887

End: 780092

Strand: Direct

Name: frc [H]

Synonym: MAP0756

Alternate gene names: 41406854

Gene position: 778887-780092 (Clockwise)

Preceding gene: 41406853

Following gene: 41406855

Centisome position: 16.13

GC content: 68.41

Gene sequence:

>1206_bases
ATGAGGCCGCTGGAAGGCATCCGCGTCCTGGAAGTCGCCATGTACGGGTTCGTCCCGTCGGCGGGCGCCGTGCTGGCCGA
GTGGGGCGCCGAGGTGGTCAAGGTCGAGCACGCGGTGACCGGTGACCCGCAGCGTGGGCTCCGCCAGACCGGGATGCTGC
GCGTCGAGGGCGATCCCAACCCCAACATCGAGCACGCCAACCGCGGCAAGCGCAGCATCGGGCTGGACATATCGGTGCCG
GAGGGCAAGGAAGTGCTCTACGAGTTGGCCCGCCGCTCGGATGTGTTCCTCACGAGCTTCCTTCCCGCTCACCGGAAGAA
GTTCGGCATCGATGTCGACGACATTCGTACGGTCAATCCGAAGATCGTCTACGCCCGAGGGAGCGCGCTCGGCCCCCGGG
GCGCCGAATCGGAAAAGGGTGGCTACGACATGACCGCCTTCTGGTGCCGGGCGGGAACCGCTGCGACGATCACGCCCGCC
GGCATGCCGGGAATGATCGCCCCGCCCGGACCGGCCTACGGTGACACCATCTCGGGCACCAACCTGGCCGGCGGCATCGC
GGCGGCACTGCTCAAGCGGGAGCGCACCGGAGAACCGTCCGTCGTCGACGTCTCGCTGCTGGGCAGCGGTCTGTGGTCGC
TGGGCCACACCGTCGCGCTGACCAATCATCTGCACCAGCGGCTGGAATCACCGCCGCCCGGAGTGCACGGCGCGCCGAAC
AATCCGTTGGTGGGGCTGTACACGACCTCCGACGGCCGCTATATCTCCTTCGTGATGATGCAGCCCACCAAGTTCTGGGC
CGACGTGTGCCGGCATGTCGACCTGCCCGAGCTGGCCGACGACCCGCGCTTCGACACGGCCGAAAACATTGCCGCCAACA
CGGCGGAAGCGGTGGAACTGCTGACCAAGGCCATCGCCACCCGGACGTTGGCCGAATGGACCGAGCGCTTCGCCACCCTC
GCCGGGCCGTGGGCGCCGGTCCAGGACACCCTGCAAGCGGCCGACGATGCCCAGATCCGGGCGAACGAGTACATCGTGCG
GGCGGGCGAGCTGGAGCTCGTCGCCAACCCGGTACAGTTCGACGTCGCAGCACCGCAGACCGGGCCGGCCCCCGGATTCG
CCGAGCAGACCGACGAGATCCTGATGGAGCTCGGCCTCGACTGGGACCGCATCATCGAACTCAAGACGGCCGGCGCCGTC
ACCTGA

Upstream 100 bases:

>100_bases
AGTCCGGCGTGGGCCGCGAGATGGGGGTTGCGGGATTGGAAGAGTTCTTGGAGCGCAAGACCTTTGCCGTTGTCGCGGGG
CCGGCCGAGGGGGCGCTCGC

Downstream 100 bases:

>100_bases
GCACTACCGGACTGGAGCAGCCCCTGACATGCCTGAGCGGACTGTCGCATGTGTTGGCACGCGGGTGCCTTACGCGTTTG
CGCAAAGCGCCGAGCGCGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MRPLEGIRVLEVAMYGFVPSAGAVLAEWGAEVVKVEHAVTGDPQRGLRQTGMLRVEGDPNPNIEHANRGKRSIGLDISVP
EGKEVLYELARRSDVFLTSFLPAHRKKFGIDVDDIRTVNPKIVYARGSALGPRGAESEKGGYDMTAFWCRAGTAATITPA
GMPGMIAPPGPAYGDTISGTNLAGGIAAALLKRERTGEPSVVDVSLLGSGLWSLGHTVALTNHLHQRLESPPPGVHGAPN
NPLVGLYTTSDGRYISFVMMQPTKFWADVCRHVDLPELADDPRFDTAENIAANTAEAVELLTKAIATRTLAEWTERFATL
AGPWAPVQDTLQAADDAQIRANEYIVRAGELELVANPVQFDVAAPQTGPAPGFAEQTDEILMELGLDWDRIIELKTAGAV
T

Sequences:

>Translated_401_residues
MRPLEGIRVLEVAMYGFVPSAGAVLAEWGAEVVKVEHAVTGDPQRGLRQTGMLRVEGDPNPNIEHANRGKRSIGLDISVP
EGKEVLYELARRSDVFLTSFLPAHRKKFGIDVDDIRTVNPKIVYARGSALGPRGAESEKGGYDMTAFWCRAGTAATITPA
GMPGMIAPPGPAYGDTISGTNLAGGIAAALLKRERTGEPSVVDVSLLGSGLWSLGHTVALTNHLHQRLESPPPGVHGAPN
NPLVGLYTTSDGRYISFVMMQPTKFWADVCRHVDLPELADDPRFDTAENIAANTAEAVELLTKAIATRTLAEWTERFATL
AGPWAPVQDTLQAADDAQIRANEYIVRAGELELVANPVQFDVAAPQTGPAPGFAEQTDEILMELGLDWDRIIELKTAGAV
T
>Mature_401_residues
MRPLEGIRVLEVAMYGFVPSAGAVLAEWGAEVVKVEHAVTGDPQRGLRQTGMLRVEGDPNPNIEHANRGKRSIGLDISVP
EGKEVLYELARRSDVFLTSFLPAHRKKFGIDVDDIRTVNPKIVYARGSALGPRGAESEKGGYDMTAFWCRAGTAATITPA
GMPGMIAPPGPAYGDTISGTNLAGGIAAALLKRERTGEPSVVDVSLLGSGLWSLGHTVALTNHLHQRLESPPPGVHGAPN
NPLVGLYTTSDGRYISFVMMQPTKFWADVCRHVDLPELADDPRFDTAENIAANTAEAVELLTKAIATRTLAEWTERFATL
AGPWAPVQDTLQAADDAQIRANEYIVRAGELELVANPVQFDVAAPQTGPAPGFAEQTDEILMELGLDWDRIIELKTAGAV
T

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate. Essential enzyme for the bacterium survival, as it relies on oxalic acid as its sole source of energy [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=414, Percent_Identity=28.2608695652174, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI300863124, Length=440, Percent_Identity=26.8181818181818, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI300863126, Length=416, Percent_Identity=25, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI266456254, Length=410, Percent_Identity=26.3414634146341, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI42794625, Length=399, Percent_Identity=25.8145363408521, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI13376042, Length=440, Percent_Identity=24.5454545454545, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI266458393, Length=263, Percent_Identity=27.7566539923954, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI266458397, Length=263, Percent_Identity=27.7566539923954, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI266458395, Length=142, Percent_Identity=30.2816901408451, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI42822893, Length=142, Percent_Identity=30.2816901408451, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082093, Length=384, Percent_Identity=25.5208333333333, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788717, Length=432, Percent_Identity=26.3888888888889, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786222, Length=354, Percent_Identity=25.9887005649718, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI32564160, Length=346, Percent_Identity=22.5433526011561, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648431, Length=404, Percent_Identity=29.4554455445545, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24585488, Length=347, Percent_Identity=25.9365994236311, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 42987; Mature: 42987

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLEGIRVLEVAMYGFVPSAGAVLAEWGAEVVKVEHAVTGDPQRGLRQTGMLRVEGDPN
CCCCHHHHHHHHHHHHCCCCCCHHHHHCCCHHEEEEHHCCCCHHHHHHHHCEEEEECCCC
PNIEHANRGKRSIGLDISVPEGKEVLYELARRSDVFLTSFLPAHRKKFGIDVDDIRTVNP
CCCCCCCCCCCEECEEEECCCHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCHHHCEECCC
KIVYARGSALGPRGAESEKGGYDMTAFWCRAGTAATITPAGMPGMIAPPGPAYGDTISGT
EEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
NLAGGIAAALLKRERTGEPSVVDVSLLGSGLWSLGHTVALTNHLHQRLESPPPGVHGAPN
CHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NPLVGLYTTSDGRYISFVMMQPTKFWADVCRHVDLPELADDPRFDTAENIAANTAEAVEL
CCEEEEEECCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCHHHHHHH
LTKAIATRTLAEWTERFATLAGPWAPVQDTLQAADDAQIRANEYIVRAGELELVANPVQF
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEECCEEEEEECCEEEEECCEEE
DVAAPQTGPAPGFAEQTDEILMELGLDWDRIIELKTAGAVT
EEECCCCCCCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCC
>Mature Secondary Structure
MRPLEGIRVLEVAMYGFVPSAGAVLAEWGAEVVKVEHAVTGDPQRGLRQTGMLRVEGDPN
CCCCHHHHHHHHHHHHCCCCCCHHHHHCCCHHEEEEHHCCCCHHHHHHHHCEEEEECCCC
PNIEHANRGKRSIGLDISVPEGKEVLYELARRSDVFLTSFLPAHRKKFGIDVDDIRTVNP
CCCCCCCCCCCEECEEEECCCHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCHHHCEECCC
KIVYARGSALGPRGAESEKGGYDMTAFWCRAGTAATITPAGMPGMIAPPGPAYGDTISGT
EEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
NLAGGIAAALLKRERTGEPSVVDVSLLGSGLWSLGHTVALTNHLHQRLESPPPGVHGAPN
CHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NPLVGLYTTSDGRYISFVMMQPTKFWADVCRHVDLPELADDPRFDTAENIAANTAEAVEL
CCEEEEEECCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCHHHHHHH
LTKAIATRTLAEWTERFATLAGPWAPVQDTLQAADDAQIRANEYIVRAGELELVANPVQF
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEECCEEEEEECCEEEEECCEEE
DVAAPQTGPAPGFAEQTDEILMELGLDWDRIIELKTAGAVT
EEECCCCCCCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9150242; 2361939 [H]