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The map label for this gene is rpoB [H]

Identifier: 39997954

GI number: 39997954

Start: 3138159

End: 3142271

Strand: Reverse

Name: rpoB [H]

Synonym: GSU2863

Alternate gene names: 39997954

Gene position: 3142271-3138159 (Counterclockwise)

Preceding gene: 39997955

Following gene: 39997953

Centisome position: 82.38

GC content: 58.86

Gene sequence:

>4113_bases
ATGGCTTATTCAATTGCGAATAACCAGCTTCTGCGCAAGAATTTCGCCAAGATCAAGAAGATCATCGACATCCCCAATCT
GATTGACATCCAGAAGAATTCCTACAAACGATTCCTCCAGATCGACACTCCCCCCGAGGCCCGCAAGAACAGTGGGCTTG
AGGCGGTTTTTAAAAGCGTCTTTCCCATAAAGGATTTCAGCGATACTGCCTCGCTTGAGTACGTTACCTATACTCTTGGC
GCTCCCAAGTATGATGTTGAGGAGTGCCACCAGCGCGGGATGACCTTCGCCGCTCCCATGAAGGTGAAGGTTCGGCTCGT
GGTCTGGGACGTGAATAAGGATACCGGCGTCCGTTCCATCCGCGATATCAAGGAGCAGGAGGTCTACTTCGGCGAGATCC
CGCTCATGACCGAGAACGGTACGTTCATCATAAATGGTACGGAGAGGGTTATCGTCAGCCAGCTCCACCGCTCACCGGGC
GTTTTCTACGACCATGACAAAGGCAAGACCCACTCCAGTGGCAAGGTGCTTTATTCGGCACGGGTAATTCCCTACCGCGG
CTCCTGGCTCGATTTCGAGTTCGACCACAAAGATATCCTCTTCGTGCGGATCGACCGCCGCCGCAAGATGCCGGCGACCG
TGCTGCTCAAGGCACTTGGCTATTCCGCCGAAGCTCTGCTGAACTACTTTTATAAGAGCGAAGAGATCCTCGTCGCCGCC
GAGGGCATGTGGAAGAAAGCCGATCCGGAGCTGCTCGCGAGCCAGAAGGCATCTGTCGACATCGTTGCGCCTAAGACGGG
CGAAGTGCTGCTCAAGGCCAACCGCAAGTTCACCAAGGCAGCAATCCGCAAGATGACTGAGCACGGCATCACGCAGATTC
CGATTACCATGGAGGAAGTGCTCGGCAAGTATGCCTCCAACGATATCGTTGACCCGTCCACCGGGGAAGTCATCGTAGAG
TGCAACGACGAGATCACCCAGGCGCGCCTCGATGACATCAAGGCTAAGGGGATCACTGAGTTCAAGGTGCTCTTCATCGA
CAACCTCCATGTGACTTCATCGCTTCGCGATACGCTCATCGCCGACAAGATTGCGGCAACGGAAGAGGCTCTCATCGAGA
TTTACCGCCGCCTGCGCCCCGGCGATCCGCCGACCCTCAAGAGCGCACAGGCCCTCTTCGAGAACCTGTTTTTCAATGCC
GAGCGGTATGACCTTTCTGCCGTTGGTCGTCTCAAGCTGAATTTCAAGCTTGGGCTGAACGTTCCCCTCGACTGCCAGAC
GCTGACGAAAGACGACGTGCTCGAGGTGGTGCGCTACCTGATCGACCTCAAGAACGGCAAGGGCACCATCGATGACATCG
ATCACCTGGGTAACCGCCGCGTGCGCGCCGTGGGCGAGCTGCTGGAGAACCAGTACCGGATCGGCCTCGTCCGTATGGAG
CGGGCCATTAAAGAGCGGATGAGTCTCCAGGAGGTCGAGAACCTCATGCCGCACGACCTGATCAACTCCAAGCCCGTCTC
AGCGGTCGTCAAGGAGTTCTTCGGTTCGTCCCAGCTCTCGCAGTTCATGGACCAGACGAACCCCCTCTCCGAGGTTACCC
ACAAGCGACGGCTCTCGGCCCTCGGACCGGGCGGTCTGACTCGCGAACGTGCTGGCTTCGAGGTCCGCGACGTACACCCG
ACCCACTACGGCCGGGTCTGCCCCATCGAGACTCCTGAAGGTCCGAACATCGGTCTCATCGCGTCCCTCTCCACTTACGC
GCGCATCAATGAGCACGGCTTTGTGGAGACCCCTTACCGCATCGTCCAGGACGGCAAGGTAACAAGCGACGTCAAGTTTT
TCTCGGCTCTGGAGGAAGAGGGGCATGCAATCGCCCAGGCCAACGCCGAGATGGACGCAGACGGCCGCTTCGTTAACGAA
TACGTATCGGCCCGCAAGTCGGGCGAGTTTCTGCTGGTCCACCGGGACGAACTCGAACTCATGGACGTTGCTCCCATGCA
GCTCGTCTCCGTGGCCGCATCGCTCATCCCGTTCCTGGAGAATGATGACGCCAACCGCGCACTCATGGGGTCGAACATGC
AGCGCCAGGCCGTGCCGCTCCTCAAGGCCGATTCGCCCCTCGTGGGCACTGGTATGGAGCGCGTCGTTGCCAAGGATTCC
GGGGTGTCAGTGGTGGCGCGCCATACCGGCATCGTCGAGTCGGTCGATGCCTCTCGCATCGTTGTCAAGATCGACGAGGA
CGAGTTCGATGAAACCGGCACCGGTGTCGACATCTACAATCTGATCAAGTTCGCCCGTTCAAACCAGAACACCTGCATCA
ACCAGCGGCCGGTGGTCAAGGTGGGCGACCATGTCAAGCGGGGCGACGTCATTGCCGACGGTCCCTCCACCGACATGGGC
GAACTCGCCCTTGGGCAGAATGTGGTTGTTGCCTTCATGCCGTGGGGCGGGTACAACTTCGAGGACTCCATCCTCGTGTC
CGAAAAGCTCGTGAAGGACGACCGCTACACCTCGATCCACATTGAGGAGTTCGAGTGCGTTGCTCGCGACACCAAACTCG
GCAAGGAGGAAATCACCTCCGATATCCCGAACCTCGGCGAAGAGGCCCTAAAGGACCTGGACGAGTCGGGGATCATCCGG
ATCGGTGCGGAGGTGAAGCCGGGAGACATCCTCGTGGGCAAGATAACCCCCAAGGGCGAAACCCAGCTTTCGCCGGAGGA
AAAGCTCCTCCGTGCCATCTTCGGCGAGAAGGCGGGAGATGTCCGCGATACCTCCCTGCGCGTCCCGCCGGGGGTCGAGG
GAACCGTCATCGGGGCCAAAATCTTCTCGCGCAAGGGGGCTGATAAGGACTCCCGTACCGAGATGATCGAGCGGATGGAA
GAGGACAAACTGCGCAAGGATGAGCAGGACGAGATCCGCATCATCCGCAATTCCGCCGTGGGCAAGCTCAAGAAGCTCCT
CGTCGGCAAGTCCGCTGCGGTCAAGGTGGAGGACAAGAGCGGCCGGACCGTCATCGCCAAGGGTGCCGCCATTACCGAAG
AGGCCCTTGACGCGATCCCGCTCGATCGTTGGGACGAGATTTCCGTGTCCGGCGAGGCGGGGGTCGATGAGAAAGTGTCG
GCGATTCTCCAGACACTCCAGCAGCAGATCGATATAATCCGTTACGTGTTCGATGACAAGGTCCAGAAGCTGAAGCGTGG
CGACGACCTGCCGCCGGGCGTCATCAAGATGGTGAAGGTCTACATCGCCATCAAGAGAAAGCTCCAGGTGGGGGACAAGA
TGGCCGGGCGCCACGGTAACAAGGGTGTCGTCTCCCGTATCCTCCCCGAAGAAGACATGCCATACATGGAGGACGGTCGT
CCGGTCGAGATCGTTCTGAACCCCCTCGGTGTTCCGTCCCGTATGAACGTGGGCCAGATTCTCGAAACCCACTTGGGATG
GGCAGCCAAGGGCATCGGCTGGAAGATCGAAGAGATGCTTGAAAGCTACTCGCCGGCCGACCACATCAAGGGCTACCTCA
AGGATGTGTATGGCACCACAGAGATGGACACATTCCTTGACTCTCTCGACAAAGACGAGCTCATGAACGTTGCAAAGCGG
CTCCAGCGGGGCGTTGCTATGGCATCCCCCGTCTTCGAGGGGGCCTCGGAGGAGCAGATCCGGAGCATGCTCGATAAAGC
CGGATTTGATGAAACCGCGCAGGTTTCCCTCTATGACGGCAAGAGCGGTGAGCCCTTCAAGCATAAGGTCACCGTCGGGG
TCATGTATGTCCTCAAACTTCATCACTTGGTCGACGATAAGATCCATGCCCGCTCCATTGGACCCTACAGCCTTGTGACC
CAGCAGCCGCTCGGCGGCAAGGCTCAGTTCGGCGGCCAGCGCCTCGGGGAGATGGAAGTCTGGGCCATGGAAGCCTACGG
TGCCGCCTATGCGCTTCAGGAATTCCTGACCGTCAAGTCCGACGACGTGGCGGGCCGGACGCGGATGTACGAGGCCATCG
TCAAAGGCAAGCACACCCTTGAGCCGGGGCTTCCAGAATCCTTCAACGTTCTTATCAAGGAACTCCAGTCCCTCTGCCTC
GATGTGGAACTGCTCGAAGGGGATGAAGACTAG

Upstream 100 bases:

>100_bases
TTTAGTTCTGAAGCGGTGACCGTAGTGACGGGAGTGGGTGCCTAGTTTCCAATAATTCCAGTGGGTTGAATGCCCCAAGG
GCATCGCCGAAGGAGAATAT

Downstream 100 bases:

>100_bases
CAGCTTGTCCGGGCCGGCCGGCATCGTCCCACCGGCCCGTTGAAACGTACACGGAAAGCACTCACTCCTACGCTGAGGAG
GATCAGACATTGGAAGATTT

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1370; Mature: 1369

Protein sequence:

>1370_residues
MAYSIANNQLLRKNFAKIKKIIDIPNLIDIQKNSYKRFLQIDTPPEARKNSGLEAVFKSVFPIKDFSDTASLEYVTYTLG
APKYDVEECHQRGMTFAAPMKVKVRLVVWDVNKDTGVRSIRDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPG
VFYDHDKGKTHSSGKVLYSARVIPYRGSWLDFEFDHKDILFVRIDRRRKMPATVLLKALGYSAEALLNYFYKSEEILVAA
EGMWKKADPELLASQKASVDIVAPKTGEVLLKANRKFTKAAIRKMTEHGITQIPITMEEVLGKYASNDIVDPSTGEVIVE
CNDEITQARLDDIKAKGITEFKVLFIDNLHVTSSLRDTLIADKIAATEEALIEIYRRLRPGDPPTLKSAQALFENLFFNA
ERYDLSAVGRLKLNFKLGLNVPLDCQTLTKDDVLEVVRYLIDLKNGKGTIDDIDHLGNRRVRAVGELLENQYRIGLVRME
RAIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHP
THYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYRIVQDGKVTSDVKFFSALEEEGHAIAQANAEMDADGRFVNE
YVSARKSGEFLLVHRDELELMDVAPMQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLKADSPLVGTGMERVVAKDS
GVSVVARHTGIVESVDASRIVVKIDEDEFDETGTGVDIYNLIKFARSNQNTCINQRPVVKVGDHVKRGDVIADGPSTDMG
ELALGQNVVVAFMPWGGYNFEDSILVSEKLVKDDRYTSIHIEEFECVARDTKLGKEEITSDIPNLGEEALKDLDESGIIR
IGAEVKPGDILVGKITPKGETQLSPEEKLLRAIFGEKAGDVRDTSLRVPPGVEGTVIGAKIFSRKGADKDSRTEMIERME
EDKLRKDEQDEIRIIRNSAVGKLKKLLVGKSAAVKVEDKSGRTVIAKGAAITEEALDAIPLDRWDEISVSGEAGVDEKVS
AILQTLQQQIDIIRYVFDDKVQKLKRGDDLPPGVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGR
PVEIVLNPLGVPSRMNVGQILETHLGWAAKGIGWKIEEMLESYSPADHIKGYLKDVYGTTEMDTFLDSLDKDELMNVAKR
LQRGVAMASPVFEGASEEQIRSMLDKAGFDETAQVSLYDGKSGEPFKHKVTVGVMYVLKLHHLVDDKIHARSIGPYSLVT
QQPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKSDDVAGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCL
DVELLEGDED

Sequences:

>Translated_1370_residues
MAYSIANNQLLRKNFAKIKKIIDIPNLIDIQKNSYKRFLQIDTPPEARKNSGLEAVFKSVFPIKDFSDTASLEYVTYTLG
APKYDVEECHQRGMTFAAPMKVKVRLVVWDVNKDTGVRSIRDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPG
VFYDHDKGKTHSSGKVLYSARVIPYRGSWLDFEFDHKDILFVRIDRRRKMPATVLLKALGYSAEALLNYFYKSEEILVAA
EGMWKKADPELLASQKASVDIVAPKTGEVLLKANRKFTKAAIRKMTEHGITQIPITMEEVLGKYASNDIVDPSTGEVIVE
CNDEITQARLDDIKAKGITEFKVLFIDNLHVTSSLRDTLIADKIAATEEALIEIYRRLRPGDPPTLKSAQALFENLFFNA
ERYDLSAVGRLKLNFKLGLNVPLDCQTLTKDDVLEVVRYLIDLKNGKGTIDDIDHLGNRRVRAVGELLENQYRIGLVRME
RAIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHP
THYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYRIVQDGKVTSDVKFFSALEEEGHAIAQANAEMDADGRFVNE
YVSARKSGEFLLVHRDELELMDVAPMQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLKADSPLVGTGMERVVAKDS
GVSVVARHTGIVESVDASRIVVKIDEDEFDETGTGVDIYNLIKFARSNQNTCINQRPVVKVGDHVKRGDVIADGPSTDMG
ELALGQNVVVAFMPWGGYNFEDSILVSEKLVKDDRYTSIHIEEFECVARDTKLGKEEITSDIPNLGEEALKDLDESGIIR
IGAEVKPGDILVGKITPKGETQLSPEEKLLRAIFGEKAGDVRDTSLRVPPGVEGTVIGAKIFSRKGADKDSRTEMIERME
EDKLRKDEQDEIRIIRNSAVGKLKKLLVGKSAAVKVEDKSGRTVIAKGAAITEEALDAIPLDRWDEISVSGEAGVDEKVS
AILQTLQQQIDIIRYVFDDKVQKLKRGDDLPPGVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGR
PVEIVLNPLGVPSRMNVGQILETHLGWAAKGIGWKIEEMLESYSPADHIKGYLKDVYGTTEMDTFLDSLDKDELMNVAKR
LQRGVAMASPVFEGASEEQIRSMLDKAGFDETAQVSLYDGKSGEPFKHKVTVGVMYVLKLHHLVDDKIHARSIGPYSLVT
QQPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKSDDVAGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCL
DVELLEGDED
>Mature_1369_residues
AYSIANNQLLRKNFAKIKKIIDIPNLIDIQKNSYKRFLQIDTPPEARKNSGLEAVFKSVFPIKDFSDTASLEYVTYTLGA
PKYDVEECHQRGMTFAAPMKVKVRLVVWDVNKDTGVRSIRDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPGV
FYDHDKGKTHSSGKVLYSARVIPYRGSWLDFEFDHKDILFVRIDRRRKMPATVLLKALGYSAEALLNYFYKSEEILVAAE
GMWKKADPELLASQKASVDIVAPKTGEVLLKANRKFTKAAIRKMTEHGITQIPITMEEVLGKYASNDIVDPSTGEVIVEC
NDEITQARLDDIKAKGITEFKVLFIDNLHVTSSLRDTLIADKIAATEEALIEIYRRLRPGDPPTLKSAQALFENLFFNAE
RYDLSAVGRLKLNFKLGLNVPLDCQTLTKDDVLEVVRYLIDLKNGKGTIDDIDHLGNRRVRAVGELLENQYRIGLVRMER
AIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPT
HYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYRIVQDGKVTSDVKFFSALEEEGHAIAQANAEMDADGRFVNEY
VSARKSGEFLLVHRDELELMDVAPMQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLKADSPLVGTGMERVVAKDSG
VSVVARHTGIVESVDASRIVVKIDEDEFDETGTGVDIYNLIKFARSNQNTCINQRPVVKVGDHVKRGDVIADGPSTDMGE
LALGQNVVVAFMPWGGYNFEDSILVSEKLVKDDRYTSIHIEEFECVARDTKLGKEEITSDIPNLGEEALKDLDESGIIRI
GAEVKPGDILVGKITPKGETQLSPEEKLLRAIFGEKAGDVRDTSLRVPPGVEGTVIGAKIFSRKGADKDSRTEMIERMEE
DKLRKDEQDEIRIIRNSAVGKLKKLLVGKSAAVKVEDKSGRTVIAKGAAITEEALDAIPLDRWDEISVSGEAGVDEKVSA
ILQTLQQQIDIIRYVFDDKVQKLKRGDDLPPGVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRP
VEIVLNPLGVPSRMNVGQILETHLGWAAKGIGWKIEEMLESYSPADHIKGYLKDVYGTTEMDTFLDSLDKDELMNVAKRL
QRGVAMASPVFEGASEEQIRSMLDKAGFDETAQVSLYDGKSGEPFKHKVTVGVMYVLKLHHLVDDKIHARSIGPYSLVTQ
QPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKSDDVAGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLD
VELLEGDED

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI238908505, Length=292, Percent_Identity=30.1369863013699, Blast_Score=130, Evalue=1e-29,
Organism=Homo sapiens, GI238908503, Length=292, Percent_Identity=30.1369863013699, Blast_Score=130, Evalue=1e-29,
Organism=Homo sapiens, GI33469941, Length=257, Percent_Identity=31.1284046692607, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI212286172, Length=257, Percent_Identity=31.1284046692607, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI4505941, Length=301, Percent_Identity=27.5747508305648, Blast_Score=116, Evalue=1e-25,
Organism=Escherichia coli, GI1790419, Length=1375, Percent_Identity=57.5272727272727, Blast_Score=1620, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=292, Percent_Identity=29.7945205479452, Blast_Score=120, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17506623, Length=246, Percent_Identity=30.0813008130081, Blast_Score=117, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17552304, Length=246, Percent_Identity=29.6747967479675, Blast_Score=116, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6324781, Length=292, Percent_Identity=30.8219178082192, Blast_Score=128, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6325267, Length=251, Percent_Identity=31.4741035856574, Blast_Score=121, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6324725, Length=269, Percent_Identity=29.368029739777, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI17647877, Length=293, Percent_Identity=30.7167235494881, Blast_Score=128, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17136446, Length=253, Percent_Identity=31.2252964426877, Blast_Score=113, Evalue=9e-25,
Organism=Drosophila melanogaster, GI17136444, Length=246, Percent_Identity=28.8617886178862, Blast_Score=112, Evalue=2e-24,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 152510; Mature: 152378

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSIANNQLLRKNFAKIKKIIDIPNLIDIQKNSYKRFLQIDTPPEARKNSGLEAVFKSV
CCEECCCCHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEEECCCCCHHHCCCHHHHHHHH
FPIKDFSDTASLEYVTYTLGAPKYDVEECHQRGMTFAAPMKVKVRLVVWDVNKDTGVRSI
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCEEECCCEEEEEEEEEECCCCCCHHHH
RDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPGVFYDHDKGKTHSSGKVLYSA
HHHHHHCEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEE
RVIPYRGSWLDFEFDHKDILFVRIDRRRKMPATVLLKALGYSAEALLNYFYKSEEILVAA
EEEEECCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEE
EGMWKKADPELLASQKASVDIVAPKTGEVLLKANRKFTKAAIRKMTEHGITQIPITMEEV
CCCCCCCCHHHHHCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCEECCEEHHHH
LGKYASNDIVDPSTGEVIVECNDEITQARLDDIKAKGITEFKVLFIDNLHVTSSLRDTLI
HHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHH
ADKIAATEEALIEIYRRLRPGDPPTLKSAQALFENLFFNAERYDLSAVGRLKLNFKLGLN
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCC
VPLDCQTLTKDDVLEVVRYLIDLKNGKGTIDDIDHLGNRRVRAVGELLENQYRIGLVRME
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHH
RAIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSA
HHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
LGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYR
CCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCCHH
IVQDGKVTSDVKFFSALEEEGHAIAQANAEMDADGRFVNEYVSARKSGEFLLVHRDELEL
HHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCH
MDVAPMQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLKADSPLVGTGMERVVAKDS
HHCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCEECCCCCCCCCHHHHHCCCC
GVSVVARHTGIVESVDASRIVVKIDEDEFDETGTGVDIYNLIKFARSNQNTCINQRPVVK
CCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
VGDHVKRGDVIADGPSTDMGELALGQNVVVAFMPWGGYNFEDSILVSEKLVKDDRYTSIH
CCCCCCCCCEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCEEEE
IEEFECVARDTKLGKEEITSDIPNLGEEALKDLDESGIIRIGAEVKPGDILVGKITPKGE
EHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCC
TQLSPEEKLLRAIFGEKAGDVRDTSLRVPPGVEGTVIGAKIFSRKGADKDSRTEMIERME
CCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEHHHHHHCCCCCCHHHHHHHHHHH
EDKLRKDEQDEIRIIRNSAVGKLKKLLVGKSAAVKVEDKSGRTVIAKGAAITEEALDAIP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCHHHHHHHHCCC
LDRWDEISVSGEAGVDEKVSAILQTLQQQIDIIRYVFDDKVQKLKRGDDLPPGVIKMVKV
CCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRPVEIVLNPLGVPSRMNVGQI
HHHHHHHHHHCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHH
LETHLGWAAKGIGWKIEEMLESYSPADHIKGYLKDVYGTTEMDTFLDSLDKDELMNVAKR
HHHHHCHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHH
LQRGVAMASPVFEGASEEQIRSMLDKAGFDETAQVSLYDGKSGEPFKHKVTVGVMYVLKL
HHHCHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHH
HHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKS
HHHHCCCHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCC
DDVAGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLDVELLEGDED
CCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCC
>Mature Secondary Structure 
AYSIANNQLLRKNFAKIKKIIDIPNLIDIQKNSYKRFLQIDTPPEARKNSGLEAVFKSV
CEECCCCHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEEECCCCCHHHCCCHHHHHHHH
FPIKDFSDTASLEYVTYTLGAPKYDVEECHQRGMTFAAPMKVKVRLVVWDVNKDTGVRSI
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCEEECCCEEEEEEEEEECCCCCCHHHH
RDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPGVFYDHDKGKTHSSGKVLYSA
HHHHHHCEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEE
RVIPYRGSWLDFEFDHKDILFVRIDRRRKMPATVLLKALGYSAEALLNYFYKSEEILVAA
EEEEECCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEE
EGMWKKADPELLASQKASVDIVAPKTGEVLLKANRKFTKAAIRKMTEHGITQIPITMEEV
CCCCCCCCHHHHHCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCEECCEEHHHH
LGKYASNDIVDPSTGEVIVECNDEITQARLDDIKAKGITEFKVLFIDNLHVTSSLRDTLI
HHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHH
ADKIAATEEALIEIYRRLRPGDPPTLKSAQALFENLFFNAERYDLSAVGRLKLNFKLGLN
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCC
VPLDCQTLTKDDVLEVVRYLIDLKNGKGTIDDIDHLGNRRVRAVGELLENQYRIGLVRME
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHH
RAIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSA
HHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
LGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYR
CCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCCHH
IVQDGKVTSDVKFFSALEEEGHAIAQANAEMDADGRFVNEYVSARKSGEFLLVHRDELEL
HHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCH
MDVAPMQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLKADSPLVGTGMERVVAKDS
HHCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCEECCCCCCCCCHHHHHCCCC
GVSVVARHTGIVESVDASRIVVKIDEDEFDETGTGVDIYNLIKFARSNQNTCINQRPVVK
CCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
VGDHVKRGDVIADGPSTDMGELALGQNVVVAFMPWGGYNFEDSILVSEKLVKDDRYTSIH
CCCCCCCCCEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCEEEE
IEEFECVARDTKLGKEEITSDIPNLGEEALKDLDESGIIRIGAEVKPGDILVGKITPKGE
EHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCC
TQLSPEEKLLRAIFGEKAGDVRDTSLRVPPGVEGTVIGAKIFSRKGADKDSRTEMIERME
CCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEHHHHHHCCCCCCHHHHHHHHHHH
EDKLRKDEQDEIRIIRNSAVGKLKKLLVGKSAAVKVEDKSGRTVIAKGAAITEEALDAIP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCHHHHHHHHCCC
LDRWDEISVSGEAGVDEKVSAILQTLQQQIDIIRYVFDDKVQKLKRGDDLPPGVIKMVKV
CCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRPVEIVLNPLGVPSRMNVGQI
HHHHHHHHHHCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHH
LETHLGWAAKGIGWKIEEMLESYSPADHIKGYLKDVYGTTEMDTFLDSLDKDELMNVAKR
HHHHHCHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHH
LQRGVAMASPVFEGASEEQIRSMLDKAGFDETAQVSLYDGKSGEPFKHKVTVGVMYVLKL
HHHCHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHH
HHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKS
HHHHCCCHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCC
DDVAGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLDVELLEGDED
CCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA