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The map label for this gene is ycbL [H]

Identifier: 39997862

GI number: 39997862

Start: 3048784

End: 3049671

Strand: Reverse

Name: ycbL [H]

Synonym: GSU2769

Alternate gene names: 39997862

Gene position: 3049671-3048784 (Counterclockwise)

Preceding gene: 39997863

Following gene: 39997860

Centisome position: 79.96

GC content: 46.85

Gene sequence:

>888_bases
ATGCAGATCACCCCACGTATCCATGCCATCAACATCCCCTTTACCGTGCCAACCCCATCCGGAACTATTAACCGATCAGT
CAACGTATTTCTTTATTGCGGCGCAAAAATTACCCTGATTGACAGCGGAGTTGCTGGATCAGAACAGCATATTTCCCAGT
ATCTAGAGCAAAGAGGACTTCAGCTACAACAGATTGAACACCTTATCCTTACTCACTCGCACCCTGATCACATTGGTGCA
GCTATGGAAATACAAAGGGCAACCGGATGCCGTGTTTCGGCTCATACGGCTGAAAGGAGCTGGATTGAAGATATCAATCT
CCAAGAAAAGGAGCGGCCTGTTCCAGGGTTTCAAACCCTTGTGGGTGGATCAGTTTCCGTTGATAATCTGCTTTATGACG
GCGAAACTATCCTCATCGATCAAGGCATTTCTTTGAAAGTCATACATACCCCAGGTCATTCAGCGGGCTCAATCTCATTA
TGGTGCCCATCTGAGAAGGTGTTATTTACTGGCGATGCCGTGCTTGTACCTGGAGATATGCCCATCTTTGACAACTATCA
ACTTGCTGTTGATTCCCTAGTGAAATTGGAGGCTATTGAGTTGGAATGGCTTTTGTCAGCATGGGATGAGCCAAAGCAGG
CTACCGAAGCTAAAATATTGTTCAGAGAAAGCATAGACTGGCTTAAGAAAATTAACGCAGCGGTGCATAACGCAGCTAGC
ATTCTTGGAACTGAAAATCATATGGAGATATGTCGCAATGTGGTGGCAGAGCTTGGCCTTCCGCAATTTGCAGTAAATCC
CCTCGTTTCACGTTCACTCATGTCTTGCCTTGCAATACATACCAACAACAAAGGCCGGGGCATTACGCCCCGGCCCGGTG
CTGTTTGA

Upstream 100 bases:

>100_bases
GGGTCACCTTCCCGCGCTCTTTTCGTATCCGCTTCTTGGAATCGAAGGTCGCGAGGGGGAAACATCTCGCGACTATTTTA
TTTCCAAAAGGAGCACTATC

Downstream 100 bases:

>100_bases
ATTAGCCGCTGTCTGCCGCGCTGCCGCGGGGAGGCGGCGTTATTTTTTCCGGCACGTTTCCGCGAAGCCGGTCACGGCGA
AGTCGCCCTGGTGATTGACC

Product: metallo-beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MQITPRIHAINIPFTVPTPSGTINRSVNVFLYCGAKITLIDSGVAGSEQHISQYLEQRGLQLQQIEHLILTHSHPDHIGA
AMEIQRATGCRVSAHTAERSWIEDINLQEKERPVPGFQTLVGGSVSVDNLLYDGETILIDQGISLKVIHTPGHSAGSISL
WCPSEKVLFTGDAVLVPGDMPIFDNYQLAVDSLVKLEAIELEWLLSAWDEPKQATEAKILFRESIDWLKKINAAVHNAAS
ILGTENHMEICRNVVAELGLPQFAVNPLVSRSLMSCLAIHTNNKGRGITPRPGAV

Sequences:

>Translated_295_residues
MQITPRIHAINIPFTVPTPSGTINRSVNVFLYCGAKITLIDSGVAGSEQHISQYLEQRGLQLQQIEHLILTHSHPDHIGA
AMEIQRATGCRVSAHTAERSWIEDINLQEKERPVPGFQTLVGGSVSVDNLLYDGETILIDQGISLKVIHTPGHSAGSISL
WCPSEKVLFTGDAVLVPGDMPIFDNYQLAVDSLVKLEAIELEWLLSAWDEPKQATEAKILFRESIDWLKKINAAVHNAAS
ILGTENHMEICRNVVAELGLPQFAVNPLVSRSLMSCLAIHTNNKGRGITPRPGAV
>Mature_295_residues
MQITPRIHAINIPFTVPTPSGTINRSVNVFLYCGAKITLIDSGVAGSEQHISQYLEQRGLQLQQIEHLILTHSHPDHIGA
AMEIQRATGCRVSAHTAERSWIEDINLQEKERPVPGFQTLVGGSVSVDNLLYDGETILIDQGISLKVIHTPGHSAGSISL
WCPSEKVLFTGDAVLVPGDMPIFDNYQLAVDSLVKLEAIELEWLLSAWDEPKQATEAKILFRESIDWLKKINAAVHNAAS
ILGTENHMEICRNVVAELGLPQFAVNPLVSRSLMSCLAIHTNNKGRGITPRPGAV

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Escherichia coli, GI1787158, Length=156, Percent_Identity=32.6923076923077, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193205216, Length=188, Percent_Identity=28.1914893617021, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17537503, Length=188, Percent_Identity=28.1914893617021, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32282; Mature: 32282

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQITPRIHAINIPFTVPTPSGTINRSVNVFLYCGAKITLIDSGVAGSEQHISQYLEQRGL
CCCCCCEEEEECCEEECCCCCCCCCCEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHCC
QLQQIEHLILTHSHPDHIGAAMEIQRATGCRVSAHTAERSWIEDINLQEKERPVPGFQTL
CHHHHHHHHHCCCCCCHHCHHEEEHHHCCCEEEECHHHHHHHHCCCCCHHCCCCCCHHHH
VGGSVSVDNLLYDGETILIDQGISLKVIHTPGHSAGSISLWCPSEKVLFTGDAVLVPGDM
CCCCCCHHHEEECCCEEEEECCCEEEEEECCCCCCCEEEEECCCCCEEEECCEEEECCCC
PIFDNYQLAVDSLVKLEAIELEWLLSAWDEPKQATEAKILFRESIDWLKKINAAVHNAAS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILGTENHMEICRNVVAELGLPQFAVNPLVSRSLMSCLAIHTNNKGRGITPRPGAV
HHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MQITPRIHAINIPFTVPTPSGTINRSVNVFLYCGAKITLIDSGVAGSEQHISQYLEQRGL
CCCCCCEEEEECCEEECCCCCCCCCCEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHCC
QLQQIEHLILTHSHPDHIGAAMEIQRATGCRVSAHTAERSWIEDINLQEKERPVPGFQTL
CHHHHHHHHHCCCCCCHHCHHEEEHHHCCCEEEECHHHHHHHHCCCCCHHCCCCCCHHHH
VGGSVSVDNLLYDGETILIDQGISLKVIHTPGHSAGSISLWCPSEKVLFTGDAVLVPGDM
CCCCCCHHHEEECCCEEEEECCCEEEEEECCCCCCCEEEEECCCCCEEEECCEEEECCCC
PIFDNYQLAVDSLVKLEAIELEWLLSAWDEPKQATEAKILFRESIDWLKKINAAVHNAAS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILGTENHMEICRNVVAELGLPQFAVNPLVSRSLMSCLAIHTNNKGRGITPRPGAV
HHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]