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The map label for this gene is moaC [H]

Identifier: 39997798

GI number: 39997798

Start: 2983379

End: 2983861

Strand: Direct

Name: moaC [H]

Synonym: GSU2704

Alternate gene names: 39997798

Gene position: 2983379-2983861 (Clockwise)

Preceding gene: 39997797

Following gene: 39997799

Centisome position: 78.22

GC content: 64.8

Gene sequence:

>483_bases
ATGTCCTTCAACCATTTTGACGACCAGGGACGGGCCATCATGGTGGACGTGAGCGGCAAGCAGCCGACCCTGCGCACCGC
TACGGCCGCCGCCACGGTGTCAATGCAGCCGGACACCCTGGCCGACCTGCTGGCCGGCCGGACCACCAAGGGCGATGTCC
TGGGCGTGGCACGGATCGCGGGTATCGCCGCCGCCAAGAAGACACCGGAGCTGATCCCCCTTTCCCACCCGCTGGCCATC
CACCATGCGGCAATCGATTTCGATACCGACCAGGCCTGCGGCACCGTCACCGTCAGAGCCACGGTACGGGCCTTCGAGCG
GACCGGCGTGGAGATGGAAGCCATGACCTCGGCGGCCGTGGCAGCTCTCACCATCTATGACATGTGCAAGGGGGCCGACA
AGGGAATCACCATCGGTCAGATTCGCCTTCTTTTCAAGGAGGGGGGGAAGAGCGGCACCTGGCAGAGGGAGGAAGGACAA
TGA

Upstream 100 bases:

>100_bases
GCTTCCCCGGGAGGCCTCGGTCGTCCCGGCCGGAAGCGAGGTGGAGATGATGATCCTGCGGGACGACGTTACGATGCTGG
AACGCTAAGGGAGATCGCGT

Downstream 100 bases:

>100_bases
AGGCGGCGATTCTTACCCTGAGCGACAAGGGCTCCCGGGGCGAACGGGCCGACGCCAGCGGCCCGGCCCTCGTCGCATGG
CTGGCGGAGCGGGGCGTCGA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSFNHFDDQGRAIMVDVSGKQPTLRTATAAATVSMQPDTLADLLAGRTTKGDVLGVARIAGIAAAKKTPELIPLSHPLAI
HHAAIDFDTDQACGTVTVRATVRAFERTGVEMEAMTSAAVAALTIYDMCKGADKGITIGQIRLLFKEGGKSGTWQREEGQ

Sequences:

>Translated_160_residues
MSFNHFDDQGRAIMVDVSGKQPTLRTATAAATVSMQPDTLADLLAGRTTKGDVLGVARIAGIAAAKKTPELIPLSHPLAI
HHAAIDFDTDQACGTVTVRATVRAFERTGVEMEAMTSAAVAALTIYDMCKGADKGITIGQIRLLFKEGGKSGTWQREEGQ
>Mature_159_residues
SFNHFDDQGRAIMVDVSGKQPTLRTATAAATVSMQPDTLADLLAGRTTKGDVLGVARIAGIAAAKKTPELIPLSHPLAIH
HAAIDFDTDQACGTVTVRATVRAFERTGVEMEAMTSAAVAALTIYDMCKGADKGITIGQIRLLFKEGGKSGTWQREEGQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=49.6774193548387, Blast_Score=145, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=38.9261744966443, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574490, Length=159, Percent_Identity=48.4276729559748, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28574492, Length=151, Percent_Identity=49.0066225165563, Blast_Score=119, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16914; Mature: 16782

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNHFDDQGRAIMVDVSGKQPTLRTATAAATVSMQPDTLADLLAGRTTKGDVLGVARIA
CCCCCCCCCCCEEEEEECCCCCCEEEEEEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHH
GIAAAKKTPELIPLSHPLAIHHAAIDFDTDQACGTVTVRATVRAFERTGVEMEAMTSAAV
HHHHCCCCCCEEECCCCEEEEEEEEECCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHH
AALTIYDMCKGADKGITIGQIRLLFKEGGKSGTWQREEGQ
HHHHHHHHHCCCCCCCCHHHEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SFNHFDDQGRAIMVDVSGKQPTLRTATAAATVSMQPDTLADLLAGRTTKGDVLGVARIA
CCCCCCCCCCEEEEEECCCCCCEEEEEEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHH
GIAAAKKTPELIPLSHPLAIHHAAIDFDTDQACGTVTVRATVRAFERTGVEMEAMTSAAV
HHHHCCCCCCEEECCCCEEEEEEEEECCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHH
AALTIYDMCKGADKGITIGQIRLLFKEGGKSGTWQREEGQ
HHHHHHHHHCCCCCCCCHHHEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA