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The map label for this gene is glnM [H]

Identifier: 39997744

GI number: 39997744

Start: 2920249

End: 2921037

Strand: Direct

Name: glnM [H]

Synonym: GSU2650

Alternate gene names: 39997744

Gene position: 2920249-2921037 (Clockwise)

Preceding gene: 39997743

Following gene: 39997745

Centisome position: 76.56

GC content: 63.88

Gene sequence:

>789_bases
ATGAACCTCCTCTTCGCACCCAATGACTGCCGGGAGGGAGGCGCCGTCCCCCTCCCGGCCCGCATCGTCGGCATCCTTAT
CGCCTTTCTCCTGGTGACGCTCATCTTTGCCTACGCCTTCCATTCCCTCCAGTACCACTGGGGGTGGGAGTCGGTCTACG
CCTACCGGCAGAAATTCGTCAACGGCTGGCTCATGACCCTCGCCATCTCGGCGGCGGCGCTGCTTCTCTCGCTCGCGATC
GGTCTCTGCACGGCCTTGACCCAGCGGAGCCGGTTGCTGCCGCTACGCTACCTGGGCCGGATCTACGTGGAGACGATCCG
GGGAACGCCGCTGCTGGTGCAGATCCTGGTGTTCTTCTATGTGGTGGCCGACGCCTTCGGCGTGGGCGACCGCTACCTGG
TGGGAGTGATCACCCTGTCGCTCTTTGCCGGCGCCTACATCTCCGAGATGATCCGGGCCGGCATCGAAAGCGTGGGCGAC
TCCCAGATGGAATCGGCCCGGGCCATCGGCCTCACTCGTGCCCAGATCTACCGGTACGTGGTCTTTCCCCAGGCGTTCCG
CCAGACCCTCCCCCCCCTGGCGGGACAGTTCGCCTCCATCGTCAAGGACTCGTCGCTCCTTTCCATCATCGCCGTGAGCG
AATTCACCCTCAACGCCCAGGAGGTGAACGCCTTCACCTACAGCACCCTGGAAAGCTACCTTCCCCTGGCCATCGGCTAC
CTGGCCATCACCCTGCCCATCTCGCTCCTCTCGCGCCGGCTCGAGAAGAAGTTCCGTTATGCAACTTAG

Upstream 100 bases:

>100_bases
CCGCAAGAAAGGCGGCTTCGAGACGCTTGGCGACAAGTACCTCAAGGAGCAGAAGGAAGCGTTCAAGAAACTGGGCTATC
CCTTCTATCTCTAGGACGCC

Downstream 100 bases:

>100_bases
ACTGACGGGGATAACTAAGCGGTTCGGGAGCCAGACCGCCCTGGCCGGCCTGTCGCTGGACATGGCCGAGTTCAAGGCCC
TGGCGGTGATCGGCCCCTCC

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNLLFAPNDCREGGAVPLPARIVGILIAFLLVTLIFAYAFHSLQYHWGWESVYAYRQKFVNGWLMTLAISAAALLLSLAI
GLCTALTQRSRLLPLRYLGRIYVETIRGTPLLVQILVFFYVVADAFGVGDRYLVGVITLSLFAGAYISEMIRAGIESVGD
SQMESARAIGLTRAQIYRYVVFPQAFRQTLPPLAGQFASIVKDSSLLSIIAVSEFTLNAQEVNAFTYSTLESYLPLAIGY
LAITLPISLLSRRLEKKFRYAT

Sequences:

>Translated_262_residues
MNLLFAPNDCREGGAVPLPARIVGILIAFLLVTLIFAYAFHSLQYHWGWESVYAYRQKFVNGWLMTLAISAAALLLSLAI
GLCTALTQRSRLLPLRYLGRIYVETIRGTPLLVQILVFFYVVADAFGVGDRYLVGVITLSLFAGAYISEMIRAGIESVGD
SQMESARAIGLTRAQIYRYVVFPQAFRQTLPPLAGQFASIVKDSSLLSIIAVSEFTLNAQEVNAFTYSTLESYLPLAIGY
LAITLPISLLSRRLEKKFRYAT
>Mature_262_residues
MNLLFAPNDCREGGAVPLPARIVGILIAFLLVTLIFAYAFHSLQYHWGWESVYAYRQKFVNGWLMTLAISAAALLLSLAI
GLCTALTQRSRLLPLRYLGRIYVETIRGTPLLVQILVFFYVVADAFGVGDRYLVGVITLSLFAGAYISEMIRAGIESVGD
SQMESARAIGLTRAQIYRYVVFPQAFRQTLPPLAGQFASIVKDSSLLSIIAVSEFTLNAQEVNAFTYSTLESYLPLAIGY
LAITLPISLLSRRLEKKFRYAT

Specific function: Part of the ABC transporter complex glnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=213, Percent_Identity=33.8028169014084, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1788226, Length=195, Percent_Identity=35.3846153846154, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=28.8288288288288, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786874, Length=243, Percent_Identity=27.9835390946502, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787087, Length=217, Percent_Identity=28.110599078341, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788646, Length=220, Percent_Identity=29.0909090909091, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082239, Length=204, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788645, Length=230, Percent_Identity=28.2608695652174, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI48994930, Length=122, Percent_Identity=38.5245901639344, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787086, Length=216, Percent_Identity=24.0740740740741, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29054; Mature: 29054

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLFAPNDCREGGAVPLPARIVGILIAFLLVTLIFAYAFHSLQYHWGWESVYAYRQKFV
CCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NGWLMTLAISAAALLLSLAIGLCTALTQRSRLLPLRYLGRIYVETIRGTPLLVQILVFFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VVADAFGVGDRYLVGVITLSLFAGAYISEMIRAGIESVGDSQMESARAIGLTRAQIYRYV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VFPQAFRQTLPPLAGQFASIVKDSSLLSIIAVSEFTLNAQEVNAFTYSTLESYLPLAIGY
HHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LAITLPISLLSRRLEKKFRYAT
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLLFAPNDCREGGAVPLPARIVGILIAFLLVTLIFAYAFHSLQYHWGWESVYAYRQKFV
CCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NGWLMTLAISAAALLLSLAIGLCTALTQRSRLLPLRYLGRIYVETIRGTPLLVQILVFFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VVADAFGVGDRYLVGVITLSLFAGAYISEMIRAGIESVGDSQMESARAIGLTRAQIYRYV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VFPQAFRQTLPPLAGQFASIVKDSSLLSIIAVSEFTLNAQEVNAFTYSTLESYLPLAIGY
HHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LAITLPISLLSRRLEKKFRYAT
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 9384377 [H]