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The map label for this gene is relE [H]

Identifier: 39997534

GI number: 39997534

Start: 2674078

End: 2674368

Strand: Direct

Name: relE [H]

Synonym: GSU2439

Alternate gene names: 39997534

Gene position: 2674078-2674368 (Clockwise)

Preceding gene: 39997533

Following gene: 39997551

Centisome position: 70.11

GC content: 51.89

Gene sequence:

>291_bases
ATGAGCTATAGCCTCGAATTCAAGGAATCCGCCCTGAAGGAGTGGAAAAAACTCGATGGCAGAATCCGTGAACAGTTTAA
GAAGAAGCTTACCGAACGGCTTGAGCTTCCTCGCGTCGAGCCGGCCCGACTCTCCGGCATGCCCGATTGCTACAAAATCA
AGCTGAAGAACGCCGGCTACCGGCTGGTTTACCAGGTTGACGACAACCGCATCATCGTTACTGTCGTGGCTGTCGGAAAA
CGCGAAAACCTTACCGTTTATCGAGCGGCAGAGAAAAGGGTGAAACAGTAA

Upstream 100 bases:

>100_bases
GCCGATGCCTTCGAGGCGCTCATGGAGAAACTGGAGGATTATGAGCTTTCCCAAATTGTGAAGGAACGGGAACACGAGCC
GAGTGTCAAGGTCTCCCTCG

Downstream 100 bases:

>100_bases
TAAATTTCGCTCTTGAAATTTGAAGGCACCACCCTTTTCTACTCCACATCAGAAATACTGACAATGATCTGCCTTAATCG
CTTTCTCTTCCAAAAACCAG

Product: RelE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MSYSLEFKESALKEWKKLDGRIREQFKKKLTERLELPRVEPARLSGMPDCYKIKLKNAGYRLVYQVDDNRIIVTVVAVGK
RENLTVYRAAEKRVKQ

Sequences:

>Translated_96_residues
MSYSLEFKESALKEWKKLDGRIREQFKKKLTERLELPRVEPARLSGMPDCYKIKLKNAGYRLVYQVDDNRIIVTVVAVGK
RENLTVYRAAEKRVKQ
>Mature_95_residues
SYSLEFKESALKEWKKLDGRIREQFKKKLTERLELPRVEPARLSGMPDCYKIKLKNAGYRLVYQVDDNRIIVTVVAVGKR
ENLTVYRAAEKRVKQ

Specific function: Inhibits translation during amino acid starvation. Acts by cleaving mRNA with high codon specificity in the ribosomal A site. UGA is cleaved with fast rate while UAA and UGA are cleaved with intermediate and slow rate, respectively. mRNA cleavage can also

COG id: COG2026

COG function: function code JD; Cytotoxic translational repressor of toxin-antitoxin stability system

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787846, Length=94, Percent_Identity=60.6382978723404, Blast_Score=120, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007712
- InterPro:   IPR012753 [H]

Pfam domain/function: PF05016 Plasmid_stabil [H]

EC number: NA

Molecular weight: Translated: 11331; Mature: 11200

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSLEFKESALKEWKKLDGRIREQFKKKLTERLELPRVEPARLSGMPDCYKIKLKNAGY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEEECCCCE
RLVYQVDDNRIIVTVVAVGKRENLTVYRAAEKRVKQ
EEEEEECCCEEEEEEEEECCCCCEEEECCHHHHCCC
>Mature Secondary Structure 
SYSLEFKESALKEWKKLDGRIREQFKKKLTERLELPRVEPARLSGMPDCYKIKLKNAGY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEEECCCCE
RLVYQVDDNRIIVTVVAVGKRENLTVYRAAEKRVKQ
EEEEEECCCEEEEEEEEECCCCCEEEECCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2990907; 9097039; 9278503; 9767574; 12526800 [H]