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The map label for this gene is kup1

Identifier: 39997446

GI number: 39997446

Start: 2567662

End: 2569557

Strand: Direct

Name: kup1

Synonym: GSU2350

Alternate gene names: 39997446

Gene position: 2567662-2569557 (Clockwise)

Preceding gene: 39997444

Following gene: 39997447

Centisome position: 67.32

GC content: 63.24

Gene sequence:

>1896_bases
ATGGAAAAGAACGGCACGGTACATACCGGCACTGTTCGTCAGTCACTGGGACTGAGCCTGGCCGCCCTGGGGGTCGTCTA
TGGCGACATCGGCACGAGCCCCCTCTATGCCATGCGCGAGTGCTTTCACGGCACACACCCCCACCCCGCCACCCCCGACA
ACGTCCTGGGCGTTCTTTCGCTGATCGTCTGGGCCTTGATTCTCATCGTCTCCCTCAAGTACCTGGTGTTTGTCCTCAGG
GCCGACAACCGGGGTGAAGGGGGCATCCTGGCCCTGACGGCGCTGCTCAACCCCTGGGGGGATGAAAACCGGCCGCCGCG
CAAGGTCCTGGTGTTTCTCGGACTCTTCGGCGCGGCCCTGCTCTACGGGGATGGAACGCTCACCCCGGCCATATCGGTCC
TGAGCGCCATCGAAGGGCTCAAGATCGCGACCCCCCTGTTTCACCCCTACATAGTTCCCATCACCGTCGTCATCCTGATC
CTGCTCTTCCTCATCCAGCACCGGGGCACGGCCCGCGTGGGCGCGCTCTTCGGCCCGGTCATGGTTCTCTGGTTCACGGT
GCTCGCCCTGCTCGGGATCAGGGGAATCATGATGGCCCCGGAGGTGCTCGGCGCCCTGAATCCGCTCCATGCCGTCCTCT
TTTTCGTCCGGGACGGGTGGAGCGGCTTTCAGGTTCTCGGCGCAGTATTCCTGGTGGTGACCGGAGGAGAAGCCCTGTAC
GCGGACATGGGACATTTCGGCCGGCTCCCCATCCGGTTGGCCTGGTTCTGCTGCGTTCTGCCGGCGCTGCTGCTCAACTA
CTTCGGGCAGGGGGCGTTGCTGCTGAGCGATCCGTCGGAGGCAACGGAACCCTTTTACCACCTGGCTCCCCCTTGGGCGC
TCTACCCTCTGGTCCTTCTTGCCACCCTGGCCACCATCATTGCGTCCCAGGCCGTGATCTCCGGCGTCTTTTCCCTCACC
CGGCAGGCCATCCAGCTGAGATTGAGTCCCAGGATGAGGATCGTCCAGACCTCATCCGAGGAGATCGGGCAGATTTACAT
CCCGGCCGTCAACTGGGCCCTGATGCTCGCCACCATCACGCTCGTTGCCGGCTTCGGCAGTTCGAGCGGCCTGGCGGCGG
CATACGGCGTGGCGGTCGCAACCACCATGGTCATTACCGCCCTGCTCGTTCGCTTTGTCATGCTGGAACGCTGGCACTGG
CATCCCCTGGCCGTTGCCGGGCTCACGGTAGTCTTTCTCACTGTCGACCTGGCCTTCTTCGGCGCCAACATCCTCAAGGT
GGGCGCCGGGGGATGGATTCCGCTGGCCGCCGGGCTGGCGGTTTTCACCGTCATGATCACCTGGCGCAGGGGACGGGAGC
TCGTCACCACTCATCTGCTGGCCCAGGCGACGCCCCTTCCCTCCTTTCTTGAGGAGCTCGCCGCAAAGCCTCCTCAACGA
GTTCCCGGCACTGCCGTTTTCATGTCGGGAAGGCTCTTTCCCGCCCCTCCGACGCTCATTCATCACCTGGAACACAACAA
GGTCCTCCACGAGCAGGTGGTGATCCTCACCGTCCTGACCGAGGACATCCCCCGGGTATCCGCCTCCGAGCGGATCGAGC
TGAAACGCCTGGGGCAGGGATTTTACCGGCTCATCGTGCGCTACGGCTTCATGCAGAGCCCCAACGTGCCGGTCATCCTG
CGGGAGTGCGAGCCGCTGGGGCTCGTTACCGATCCCGAGACAACCACCTTTTATCTGGGCCGCGAAACCCTTATCCCCAC
GGAAAAAGTCAGCGGAATGCCCCATTGGCGGGAAAAGCTCTTCGCCTTCATGTCCCGCAACTCTCTTCAAGCCACGGCAT
TTTACAATCTCCCGCCCGACCGTGTGGTCGAACTGGGGCAGCAGGTGGAAATTTGA

Upstream 100 bases:

>100_bases
GAACGCCATGATCTGTGTACGGTGGGCCGATCGGCGTTTCAGGGTGCCGGGAACGGCTCCCGCAGTGGCGTGGCTCCAGC
CGGAGTAAAACGGGGTAACC

Downstream 100 bases:

>100_bases
ACGGGCACTGCAACTCCCCTGGAGGGAAATGATGGCAGCGTGATGAGCGCCCGGAAACCACCGGGACCATTGGAGCACCG
GGTGGGTCACGAGGCGTAGC

Product: potassium uptake protein, Kup system

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MEKNGTVHTGTVRQSLGLSLAALGVVYGDIGTSPLYAMRECFHGTHPHPATPDNVLGVLSLIVWALILIVSLKYLVFVLR
ADNRGEGGILALTALLNPWGDENRPPRKVLVFLGLFGAALLYGDGTLTPAISVLSAIEGLKIATPLFHPYIVPITVVILI
LLFLIQHRGTARVGALFGPVMVLWFTVLALLGIRGIMMAPEVLGALNPLHAVLFFVRDGWSGFQVLGAVFLVVTGGEALY
ADMGHFGRLPIRLAWFCCVLPALLLNYFGQGALLLSDPSEATEPFYHLAPPWALYPLVLLATLATIIASQAVISGVFSLT
RQAIQLRLSPRMRIVQTSSEEIGQIYIPAVNWALMLATITLVAGFGSSSGLAAAYGVAVATTMVITALLVRFVMLERWHW
HPLAVAGLTVVFLTVDLAFFGANILKVGAGGWIPLAAGLAVFTVMITWRRGRELVTTHLLAQATPLPSFLEELAAKPPQR
VPGTAVFMSGRLFPAPPTLIHHLEHNKVLHEQVVILTVLTEDIPRVSASERIELKRLGQGFYRLIVRYGFMQSPNVPVIL
RECEPLGLVTDPETTTFYLGRETLIPTEKVSGMPHWREKLFAFMSRNSLQATAFYNLPPDRVVELGQQVEI

Sequences:

>Translated_631_residues
MEKNGTVHTGTVRQSLGLSLAALGVVYGDIGTSPLYAMRECFHGTHPHPATPDNVLGVLSLIVWALILIVSLKYLVFVLR
ADNRGEGGILALTALLNPWGDENRPPRKVLVFLGLFGAALLYGDGTLTPAISVLSAIEGLKIATPLFHPYIVPITVVILI
LLFLIQHRGTARVGALFGPVMVLWFTVLALLGIRGIMMAPEVLGALNPLHAVLFFVRDGWSGFQVLGAVFLVVTGGEALY
ADMGHFGRLPIRLAWFCCVLPALLLNYFGQGALLLSDPSEATEPFYHLAPPWALYPLVLLATLATIIASQAVISGVFSLT
RQAIQLRLSPRMRIVQTSSEEIGQIYIPAVNWALMLATITLVAGFGSSSGLAAAYGVAVATTMVITALLVRFVMLERWHW
HPLAVAGLTVVFLTVDLAFFGANILKVGAGGWIPLAAGLAVFTVMITWRRGRELVTTHLLAQATPLPSFLEELAAKPPQR
VPGTAVFMSGRLFPAPPTLIHHLEHNKVLHEQVVILTVLTEDIPRVSASERIELKRLGQGFYRLIVRYGFMQSPNVPVIL
RECEPLGLVTDPETTTFYLGRETLIPTEKVSGMPHWREKLFAFMSRNSLQATAFYNLPPDRVVELGQQVEI
>Mature_631_residues
MEKNGTVHTGTVRQSLGLSLAALGVVYGDIGTSPLYAMRECFHGTHPHPATPDNVLGVLSLIVWALILIVSLKYLVFVLR
ADNRGEGGILALTALLNPWGDENRPPRKVLVFLGLFGAALLYGDGTLTPAISVLSAIEGLKIATPLFHPYIVPITVVILI
LLFLIQHRGTARVGALFGPVMVLWFTVLALLGIRGIMMAPEVLGALNPLHAVLFFVRDGWSGFQVLGAVFLVVTGGEALY
ADMGHFGRLPIRLAWFCCVLPALLLNYFGQGALLLSDPSEATEPFYHLAPPWALYPLVLLATLATIIASQAVISGVFSLT
RQAIQLRLSPRMRIVQTSSEEIGQIYIPAVNWALMLATITLVAGFGSSSGLAAAYGVAVATTMVITALLVRFVMLERWHW
HPLAVAGLTVVFLTVDLAFFGANILKVGAGGWIPLAAGLAVFTVMITWRRGRELVTTHLLAQATPLPSFLEELAAKPPQR
VPGTAVFMSGRLFPAPPTLIHHLEHNKVLHEQVVILTVLTEDIPRVSASERIELKRLGQGFYRLIVRYGFMQSPNVPVIL
RECEPLGLVTDPETTTFYLGRETLIPTEKVSGMPHWREKLFAFMSRNSLQATAFYNLPPDRVVELGQQVEI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=625, Percent_Identity=50.24, Blast_Score=595, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP1_GEOSL (Q74AK4)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_953397.1
- GeneID:   2686160
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU2350
- NMPDR:   fig|243231.1.peg.2335
- TIGR:   GSU2350
- HOGENOM:   HBG351154
- OMA:   FVIRYSW
- ProtClustDB:   CLSK763201
- BioCyc:   GSUL243231:GSU_2350-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 68732; Mature: 68732

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1070e764)-; HASH(0xb9c4624)-; HASH(0x107422f4)-; HASH(0x10794a60)-; HASH(0xb9c4684)-; HASH(0x1076a9a0)-; HASH(0x107b1724)-; HASH(0xe75d524)-; HASH(0x10799948)-; HASH(0x10797c2c)-; HASH(0xe75d41c)-; HASH(0x107b17f0)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNGTVHTGTVRQSLGLSLAALGVVYGDIGTSPLYAMRECFHGTHPHPATPDNVLGVLS
CCCCCCEEECHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
LIVWALILIVSLKYLVFVLRADNRGEGGILALTALLNPWGDENRPPRKVLVFLGLFGAAL
HHHHHHHHHHHHHHHHEEEECCCCCCCCCEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LYGDGTLTPAISVLSAIEGLKIATPLFHPYIVPITVVILILLFLIQHRGTARVGALFGPV
HCCCCCHHHHHHHHHHHCCCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MVLWFTVLALLGIRGIMMAPEVLGALNPLHAVLFFVRDGWSGFQVLGAVFLVVTGGEALY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHEECCCHHH
ADMGHFGRLPIRLAWFCCVLPALLLNYFGQGALLLSDPSEATEPFYHLAPPWALYPLVLL
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHCCCEECCCCHHHHHHHHH
ATLATIIASQAVISGVFSLTRQAIQLRLSPRMRIVQTSSEEIGQIYIPAVNWALMLATIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCEEEEHHHHHHHHHHHHH
LVAGFGSSSGLAAAYGVAVATTMVITALLVRFVMLERWHWHPLAVAGLTVVFLTVDLAFF
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GANILKVGAGGWIPLAAGLAVFTVMITWRRGRELVTTHLLAQATPLPSFLEELAAKPPQR
CCHHEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
VPGTAVFMSGRLFPAPPTLIHHLEHNKVLHEQVVILTVLTEDIPRVSASERIELKRLGQG
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FYRLIVRYGFMQSPNVPVILRECEPLGLVTDPETTTFYLGRETLIPTEKVSGMPHWREKL
HHHHHHHHCCCCCCCCCEEEECCCCCCCEECCCCCEEEECCCCCCCHHHHCCCCHHHHHH
FAFMSRNSLQATAFYNLPPDRVVELGQQVEI
HHHHHCCCCEEEEEECCCHHHHHHHHHHCCH
>Mature Secondary Structure
MEKNGTVHTGTVRQSLGLSLAALGVVYGDIGTSPLYAMRECFHGTHPHPATPDNVLGVLS
CCCCCCEEECHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
LIVWALILIVSLKYLVFVLRADNRGEGGILALTALLNPWGDENRPPRKVLVFLGLFGAAL
HHHHHHHHHHHHHHHHEEEECCCCCCCCCEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LYGDGTLTPAISVLSAIEGLKIATPLFHPYIVPITVVILILLFLIQHRGTARVGALFGPV
HCCCCCHHHHHHHHHHHCCCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MVLWFTVLALLGIRGIMMAPEVLGALNPLHAVLFFVRDGWSGFQVLGAVFLVVTGGEALY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHEECCCHHH
ADMGHFGRLPIRLAWFCCVLPALLLNYFGQGALLLSDPSEATEPFYHLAPPWALYPLVLL
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHCCCEECCCCHHHHHHHHH
ATLATIIASQAVISGVFSLTRQAIQLRLSPRMRIVQTSSEEIGQIYIPAVNWALMLATIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCEEEEHHHHHHHHHHHHH
LVAGFGSSSGLAAAYGVAVATTMVITALLVRFVMLERWHWHPLAVAGLTVVFLTVDLAFF
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GANILKVGAGGWIPLAAGLAVFTVMITWRRGRELVTTHLLAQATPLPSFLEELAAKPPQR
CCHHEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
VPGTAVFMSGRLFPAPPTLIHHLEHNKVLHEQVVILTVLTEDIPRVSASERIELKRLGQG
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FYRLIVRYGFMQSPNVPVILRECEPLGLVTDPETTTFYLGRETLIPTEKVSGMPHWREKL
HHHHHHHHCCCCCCCCCEEEECCCCCCCEECCCCCEEEECCCCCCCHHHHCCCCHHHHHH
FAFMSRNSLQATAFYNLPPDRVVELGQQVEI
HHHHHCCCCEEEEEECCCHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA