Click here to switch to the map view.

The map label for this gene is cfa [H]

Identifier: 39997426

GI number: 39997426

Start: 2547960

End: 2549225

Strand: Direct

Name: cfa [H]

Synonym: GSU2329

Alternate gene names: 39997426

Gene position: 2547960-2549225 (Clockwise)

Preceding gene: 39997425

Following gene: 39997427

Centisome position: 66.8

GC content: 66.75

Gene sequence:

>1266_bases
ATGAGGACTACCGAGCAGACCTGCAGTGGCTATCCCGACGCCGTAATCCGGCCGGCCGGCCCCATGGAGCGCCTGGCCCG
GTCCCTGTTGCAGAAAAGCCTTGGAGCCATCTCCAGCGGCCACCTGACCCTGCTGGACAGCGGCCAGCGCATGGAATTCG
GCGATTCCCGGTCCGACCTCTCGGCCCTGGTGCGGGTCCACACCCCTTCCTTTTACCGCCGGACCGCCATCGGAGGAACC
ATCGGCGCCGCCGAGTCGTACATGGACGGCGAATGGGACTGTGATGACCTGCCGGCCCTGGTGCGGATCATGGTGCGCAA
CCAGGATGCCCAGGAGCGCCTGGAAGGAGCGACGGCGAGGCTGATCGCCCCGTTCCGGCGGCTCCTCCACCGGCTGAACG
ACAACACGCGCCGGGGGAGCCGGCGCAACATCGCCGCCCACTACGACCTGGGAAACGACTTCTACCGACTCTTTCTGGAT
CCCACCATGGCCTACTCCTGCGGCATCTTCGAGCGGAACGACAGCACCATGGAGGAGGCCTCCGTCGCCAAGTTTGACCG
GATCTGCCGCGCGCTCCACCTTCGCCCGGACATGGAGCTTCTTGAAATCGGCACCGGCTGGGGAGGCTTTGCCATCCATG
CGGCCGAGCACTACGGCTGCCGGGTGACGACCACCACCATCTCGCGCCGGCAGTTCTCCCTGGCGGCCGAACGGATCCGG
GAGGCCGGCCTGGACGATCGCATCACCCTGCTCCAGCGGGACTACCGGGACCTGACCGGAGAGTTCGACCGGCTCGTCTC
CATCGAGATGATCGAGGCGGTGGGGCACCGCCACCTCCCCGCCTTCTTTGCAGTCTGTTGCCGGCGGCTCAAGGCCGACG
GCATGGGACTCATCCAGGCCATCACTGTCCCCGACCGGATCTATGACCGCTACCTCAAAACCCCGGACTTCATCAACCGC
TACATTTTCCCCGGTGGGTGCTGTCCGTCGCCGGGGGCCATGGCCCGGGCCGTGGCAGCGGCCACCGACCTGCGCCTGGT
CCACCGGGAGGACCTGACTCCCCACTATGTCCGAACCCTCCAGGAGTGGCGCAGGACCTTCCACAAGCGGCTCGACGCCG
TACGGGCCCTGGGCTGCGACGACCGGTTCATCCGCATGTGGGACTATTATCTCGCCTACTGCGAAGGGGGATTCGCGGAG
CGGTTCACCGGCGTGGAACAGGTGGTCTACGCCCGGCCCGGCTGCATGGTGGAACCGGGGGTATAG

Upstream 100 bases:

>100_bases
TAACCGCCATTTACTGGCAGGCCCTGCGCATCAGGCGAAAGGGGGTTCCGTTCTGCCCCCATCCGGAAAAACTCACCATC
ACGAAAGGGGCCTACCACCC

Downstream 100 bases:

>100_bases
GTGGGAAGAAACCTTCTCAATGTGGCCCTCTTCCAGGGGGCCTGGTTCGCGGCGGTGCTGGGGGCAGCCGGGGGGCGGCA
CTGGCTCGGGCCGGCGGCGG

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MRTTEQTCSGYPDAVIRPAGPMERLARSLLQKSLGAISSGHLTLLDSGQRMEFGDSRSDLSALVRVHTPSFYRRTAIGGT
IGAAESYMDGEWDCDDLPALVRIMVRNQDAQERLEGATARLIAPFRRLLHRLNDNTRRGSRRNIAAHYDLGNDFYRLFLD
PTMAYSCGIFERNDSTMEEASVAKFDRICRALHLRPDMELLEIGTGWGGFAIHAAEHYGCRVTTTTISRRQFSLAAERIR
EAGLDDRITLLQRDYRDLTGEFDRLVSIEMIEAVGHRHLPAFFAVCCRRLKADGMGLIQAITVPDRIYDRYLKTPDFINR
YIFPGGCCPSPGAMARAVAAATDLRLVHREDLTPHYVRTLQEWRRTFHKRLDAVRALGCDDRFIRMWDYYLAYCEGGFAE
RFTGVEQVVYARPGCMVEPGV

Sequences:

>Translated_421_residues
MRTTEQTCSGYPDAVIRPAGPMERLARSLLQKSLGAISSGHLTLLDSGQRMEFGDSRSDLSALVRVHTPSFYRRTAIGGT
IGAAESYMDGEWDCDDLPALVRIMVRNQDAQERLEGATARLIAPFRRLLHRLNDNTRRGSRRNIAAHYDLGNDFYRLFLD
PTMAYSCGIFERNDSTMEEASVAKFDRICRALHLRPDMELLEIGTGWGGFAIHAAEHYGCRVTTTTISRRQFSLAAERIR
EAGLDDRITLLQRDYRDLTGEFDRLVSIEMIEAVGHRHLPAFFAVCCRRLKADGMGLIQAITVPDRIYDRYLKTPDFINR
YIFPGGCCPSPGAMARAVAAATDLRLVHREDLTPHYVRTLQEWRRTFHKRLDAVRALGCDDRFIRMWDYYLAYCEGGFAE
RFTGVEQVVYARPGCMVEPGV
>Mature_421_residues
MRTTEQTCSGYPDAVIRPAGPMERLARSLLQKSLGAISSGHLTLLDSGQRMEFGDSRSDLSALVRVHTPSFYRRTAIGGT
IGAAESYMDGEWDCDDLPALVRIMVRNQDAQERLEGATARLIAPFRRLLHRLNDNTRRGSRRNIAAHYDLGNDFYRLFLD
PTMAYSCGIFERNDSTMEEASVAKFDRICRALHLRPDMELLEIGTGWGGFAIHAAEHYGCRVTTTTISRRQFSLAAERIR
EAGLDDRITLLQRDYRDLTGEFDRLVSIEMIEAVGHRHLPAFFAVCCRRLKADGMGLIQAITVPDRIYDRYLKTPDFINR
YIFPGGCCPSPGAMARAVAAATDLRLVHREDLTPHYVRTLQEWRRTFHKRLDAVRALGCDDRFIRMWDYYLAYCEGGFAE
RFTGVEQVVYARPGCMVEPGV

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=362, Percent_Identity=37.5690607734807, Blast_Score=208, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI133904226, Length=396, Percent_Identity=33.5858585858586, Blast_Score=229, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 47750; Mature: 47750

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTEQTCSGYPDAVIRPAGPMERLARSLLQKSLGAISSGHLTLLDSGQRMEFGDSRSDL
CCCCCCHHCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHH
SALVRVHTPSFYRRTAIGGTIGAAESYMDGEWDCDDLPALVRIMVRNQDAQERLEGATAR
HHHHHHCCCHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LIAPFRRLLHRLNDNTRRGSRRNIAAHYDLGNDFYRLFLDPTMAYSCGIFERNDSTMEEA
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHEEECCHHHHHCCCEECCCCHHHHH
SVAKFDRICRALHLRPDMELLEIGTGWGGFAIHAAEHYGCRVTTTTISRRQFSLAAERIR
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEHHHCCCEEEEEHHHHHHHHHHHHHHH
EAGLDDRITLLQRDYRDLTGEFDRLVSIEMIEAVGHRHLPAFFAVCCRRLKADGMGLIQA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEE
ITVPDRIYDRYLKTPDFINRYIFPGGCCPSPGAMARAVAAATDLRLVHREDLTPHYVRTL
ECCCHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
QEWRRTFHKRLDAVRALGCDDRFIRMWDYYLAYCEGGFAERFTGVEQVVYARPGCMVEPG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEECCC
V
C
>Mature Secondary Structure
MRTTEQTCSGYPDAVIRPAGPMERLARSLLQKSLGAISSGHLTLLDSGQRMEFGDSRSDL
CCCCCCHHCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHH
SALVRVHTPSFYRRTAIGGTIGAAESYMDGEWDCDDLPALVRIMVRNQDAQERLEGATAR
HHHHHHCCCHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LIAPFRRLLHRLNDNTRRGSRRNIAAHYDLGNDFYRLFLDPTMAYSCGIFERNDSTMEEA
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHEEECCHHHHHCCCEECCCCHHHHH
SVAKFDRICRALHLRPDMELLEIGTGWGGFAIHAAEHYGCRVTTTTISRRQFSLAAERIR
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEHHHCCCEEEEEHHHHHHHHHHHHHHH
EAGLDDRITLLQRDYRDLTGEFDRLVSIEMIEAVGHRHLPAFFAVCCRRLKADGMGLIQA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEE
ITVPDRIYDRYLKTPDFINRYIFPGGCCPSPGAMARAVAAATDLRLVHREDLTPHYVRTL
ECCCHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
QEWRRTFHKRLDAVRALGCDDRFIRMWDYYLAYCEGGFAERFTGVEQVVYARPGCMVEPG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEECCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]