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The map label for this gene is icfA [H]

Identifier: 39997405

GI number: 39997405

Start: 2524394

End: 2525029

Strand: Direct

Name: icfA [H]

Synonym: GSU2307

Alternate gene names: 39997405

Gene position: 2524394-2525029 (Clockwise)

Preceding gene: 39997404

Following gene: 39997406

Centisome position: 66.19

GC content: 58.49

Gene sequence:

>636_bases
ATGAAGGACATCGAACGCTTCATCGCAGGATTCCGCCGGTTCAGAGAGGATTATTTCGGTTCGGAATACTCACCCTTCGA
ACACCTTAAGCAGGGGCAAAGCCCCAAGACCATGATCATCGGCTGTTCCGATTCCCGGGTCGATCCGGCCATCCTGACCG
ACTGTGCGCCTGGCGACATCTTCACCGTTCGCAACGTGGCCAACCTGGTCCCCCCCTTCGAGGAAAACGGCGGGCTTCAC
GGGGTAAGTGCGGCATTGGAATTCGCGGTCTGCCACCTGGGGGTCGAGCATATCATCGTACTTGGGCACTCCCAGTGCGG
CGGCATTAACGCCCTCATGAAAGGAACCTGCGGCTGCAAGGGGGGAGGGTTTATCTCCCGCTGGATGTCAATCGCCACGC
CCGCCCGCGAACGGGTCCTGGCGGAGCTGCCGGAAAAGGATACGGCCCTCCAGCAGCGGGCCGCCGAGCAGGCCGCCATC
CTCCTCTCTCTGGAAAATCTCCACTCCTTCCCTTGGATCGACGAGCGGGTGGTACGGGGGGAACTCACTCTGCATGGGTG
GTATTTCGATATCTCAGCTGGTGAACTGCTCGAATATCGATCCGAAACCGGATTATTCGAAAAAGTCTCTAAATAA

Upstream 100 bases:

>100_bases
TGACCGCCGATGAGGCCCTGGCAAAACTCACCTCGTGCGTCAAGTAATGAAGGAGAGAACGCGCGGCGCCCTTTCCCGGG
CGCCGCGCCATGGAGGCACT

Downstream 100 bases:

>100_bases
CAGAGCATTTCTGGGAACTGATTTTCTCCGTGATCGTCGGTGAATACCGGCGAACCAGCCGGGTAGCCGCTGCCAGATAT
TAGCCACCACTCATCAGACC

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MKDIERFIAGFRRFREDYFGSEYSPFEHLKQGQSPKTMIIGCSDSRVDPAILTDCAPGDIFTVRNVANLVPPFEENGGLH
GVSAALEFAVCHLGVEHIIVLGHSQCGGINALMKGTCGCKGGGFISRWMSIATPARERVLAELPEKDTALQQRAAEQAAI
LLSLENLHSFPWIDERVVRGELTLHGWYFDISAGELLEYRSETGLFEKVSK

Sequences:

>Translated_211_residues
MKDIERFIAGFRRFREDYFGSEYSPFEHLKQGQSPKTMIIGCSDSRVDPAILTDCAPGDIFTVRNVANLVPPFEENGGLH
GVSAALEFAVCHLGVEHIIVLGHSQCGGINALMKGTCGCKGGGFISRWMSIATPARERVLAELPEKDTALQQRAAEQAAI
LLSLENLHSFPWIDERVVRGELTLHGWYFDISAGELLEYRSETGLFEKVSK
>Mature_211_residues
MKDIERFIAGFRRFREDYFGSEYSPFEHLKQGQSPKTMIIGCSDSRVDPAILTDCAPGDIFTVRNVANLVPPFEENGGLH
GVSAALEFAVCHLGVEHIIVLGHSQCGGINALMKGTCGCKGGGFISRWMSIATPARERVLAELPEKDTALQQRAAEQAAI
LLSLENLHSFPWIDERVVRGELTLHGWYFDISAGELLEYRSETGLFEKVSK

Specific function: Reversible hydration of carbon dioxide. Essential to photosynthetic carbon dioxide fixation [H]

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=211, Percent_Identity=35.0710900473934, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786318, Length=203, Percent_Identity=33.0049261083744, Blast_Score=88, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI25147564, Length=242, Percent_Identity=29.3388429752066, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115532990, Length=241, Percent_Identity=27.8008298755187, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324292, Length=191, Percent_Identity=29.3193717277487, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24645213, Length=233, Percent_Identity=25.3218884120172, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23329; Mature: 23329

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIERFIAGFRRFREDYFGSEYSPFEHLKQGQSPKTMIIGCSDSRVDPAILTDCAPGDI
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEEECCCCCCCHHHCCCCCCCCE
FTVRNVANLVPPFEENGGLHGVSAALEFAVCHLGVEHIIVLGHSQCGGINALMKGTCGCK
EHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCHHHEEEECCCCCCCHHHHHHCCCCCC
GGGFISRWMSIATPARERVLAELPEKDTALQQRAAEQAAILLSLENLHSFPWIDERVVRG
CCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCC
ELTLHGWYFDISAGELLEYRSETGLFEKVSK
EEEEEEEEEECCHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MKDIERFIAGFRRFREDYFGSEYSPFEHLKQGQSPKTMIIGCSDSRVDPAILTDCAPGDI
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEEECCCCCCCHHHCCCCCCCCE
FTVRNVANLVPPFEENGGLHGVSAALEFAVCHLGVEHIIVLGHSQCGGINALMKGTCGCK
EHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCHHHEEEECCCCCCCHHHHHHCCCCCC
GGGFISRWMSIATPARERVLAELPEKDTALQQRAAEQAAILLSLENLHSFPWIDERVVRG
CCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCC
ELTLHGWYFDISAGELLEYRSETGLFEKVSK
EEEEEEEEEECCHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584776 [H]