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The map label for this gene is mtaD [H]

Identifier: 39996808

GI number: 39996808

Start: 1872319

End: 1873581

Strand: Direct

Name: mtaD [H]

Synonym: GSU1708

Alternate gene names: 39996808

Gene position: 1872319-1873581 (Clockwise)

Preceding gene: 39996807

Following gene: 39996809

Centisome position: 49.09

GC content: 60.49

Gene sequence:

>1263_bases
ATGGAGCTCTACGCCGCCTCATACCTTGTTCCCATTTCATCGCCCCCTGTCGCCGGCGGCGCACTAGCCGTCGACAATGG
CCGGATAGTCGATACGGGTACGTTTGCCGAGCTTCGTGCCCGGTACGGCTGTCCCGTTCACGACTTTCCGGGCTGCACCA
TTCTTCCCGGCCTCGTCAACGCCCACACGCACCTGGAGCTTACCCATTTCCCGTCATGGAAAATCCGCAAGGGAATCGAT
TACTCACCCCGGACGTACGTTGATTGGATCATCCAGGTAATAAAGATCCGCCGGGCCCTGACGCGGCAGGAACAGGAACT
TTCCGTACGGGAAGGGCTGCGCATCTGCCTTGAAGCGGGGACCACGTCCATCGGCGAAATTCTCACCGACCGGTCGCTCC
TCCCTCTGTATGCCGATTCCGGCCTGGGGGGGCGGCTTTTTCTCGAGGCCATAGGCCACGACCCGGTCCGCAGCGCCGAG
CTCATCTCGGAGCTTGGTGCCGCCGTAGCTTCTTTCCCTGCTGGAGACTTACTGCCGGGCCTCTCGCCCCATGCCCCCCA
CACTGTTTCTGAGCAGCTCCATCAGAATGTTCGCCGGCTGGCGGAAGAGTACAACGTGCCGCGAATCATCCATCTGGCCG
AATCCCGGGAAGAGAGTGATTTCTTCTTCGATTCGACCGGAAAAATTGCTGAGCTTCTCTATTCCCACGTCAGGTGGGAG
TCGTACCTTCCCGCCCCGAGACGTGCTACCGCAACCGCCTGGCTTGACGGACTCGGCGTCCTCAACGGTGCCATCTCGGC
GGTCCACTGCGTTCATCTTACGCCGTCGGATGCCGAAACCCTGGCCAAACGCGGAGTCGGCATTGTGCTTTGCCCCCGGA
GCAACGAAAAGCTTGCTGTGGGGCGCGCACCTGTCGCCTATTTGAAGAAACTTGGTATTCCCCTTGCCTTGGGCACCGAC
TCGCTGGCCAGCAACGATTCCCTCTCACTCTGGGATGAAATGCGTTACCTCCTCGATCTCTTCCCGGGCGTCTTCACCCC
GTCAGAGGCCCTTGCCATGGCAACCATCGGTTCGGCACGACAGCTCGCTCTCGCCGATCGGGTAGGGTCCATCGAGAAGG
GCAAACGCGCCGATCTGCTTGTCATGAAACTACCTGGTCCGCAGAGCACCGGCGAAGGACTCCACGAAGCCGTTATCGGC
AGCGGAGAACTTCTCCATGTGATTCTGTCCGGCAGGTTCACCGACCGGACAGAACCCCGCTAA

Upstream 100 bases:

>100_bases
AGAGCTCTGTACCGGCTTGGCAAAAGCAGCTTCATGGTAGAAGCATGACGTTCTGTTTGTGCTAACGAGCGGGATGATTG
ACTAAGCGAGGATCAGTACG

Downstream 100 bases:

>100_bases
TTCCCCCTCAAATAGCGGACAACCATAGTCTTTTTTACTCCTTGCAATGATTTCACCATATCTGTTAGTATCATTTGCAT
GGGAGAAAAGCTGATCTGCA

Product: Atz/Trz family chlorohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MELYAASYLVPISSPPVAGGALAVDNGRIVDTGTFAELRARYGCPVHDFPGCTILPGLVNAHTHLELTHFPSWKIRKGID
YSPRTYVDWIIQVIKIRRALTRQEQELSVREGLRICLEAGTTSIGEILTDRSLLPLYADSGLGGRLFLEAIGHDPVRSAE
LISELGAAVASFPAGDLLPGLSPHAPHTVSEQLHQNVRRLAEEYNVPRIIHLAESREESDFFFDSTGKIAELLYSHVRWE
SYLPAPRRATATAWLDGLGVLNGAISAVHCVHLTPSDAETLAKRGVGIVLCPRSNEKLAVGRAPVAYLKKLGIPLALGTD
SLASNDSLSLWDEMRYLLDLFPGVFTPSEALAMATIGSARQLALADRVGSIEKGKRADLLVMKLPGPQSTGEGLHEAVIG
SGELLHVILSGRFTDRTEPR

Sequences:

>Translated_420_residues
MELYAASYLVPISSPPVAGGALAVDNGRIVDTGTFAELRARYGCPVHDFPGCTILPGLVNAHTHLELTHFPSWKIRKGID
YSPRTYVDWIIQVIKIRRALTRQEQELSVREGLRICLEAGTTSIGEILTDRSLLPLYADSGLGGRLFLEAIGHDPVRSAE
LISELGAAVASFPAGDLLPGLSPHAPHTVSEQLHQNVRRLAEEYNVPRIIHLAESREESDFFFDSTGKIAELLYSHVRWE
SYLPAPRRATATAWLDGLGVLNGAISAVHCVHLTPSDAETLAKRGVGIVLCPRSNEKLAVGRAPVAYLKKLGIPLALGTD
SLASNDSLSLWDEMRYLLDLFPGVFTPSEALAMATIGSARQLALADRVGSIEKGKRADLLVMKLPGPQSTGEGLHEAVIG
SGELLHVILSGRFTDRTEPR
>Mature_420_residues
MELYAASYLVPISSPPVAGGALAVDNGRIVDTGTFAELRARYGCPVHDFPGCTILPGLVNAHTHLELTHFPSWKIRKGID
YSPRTYVDWIIQVIKIRRALTRQEQELSVREGLRICLEAGTTSIGEILTDRSLLPLYADSGLGGRLFLEAIGHDPVRSAE
LISELGAAVASFPAGDLLPGLSPHAPHTVSEQLHQNVRRLAEEYNVPRIIHLAESREESDFFFDSTGKIAELLYSHVRWE
SYLPAPRRATATAWLDGLGVLNGAISAVHCVHLTPSDAETLAKRGVGIVLCPRSNEKLAVGRAPVAYLKKLGIPLALGTD
SLASNDSLSLWDEMRYLLDLFPGVFTPSEALAMATIGSARQLALADRVGSIEKGKRADLLVMKLPGPQSTGEGLHEAVIG
SGELLHVILSGRFTDRTEPR

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319963, Length=366, Percent_Identity=24.0437158469945, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 45507; Mature: 45507

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELYAASYLVPISSPPVAGGALAVDNGRIVDTGTFAELRARYGCPVHDFPGCTILPGLVN
CCEEECEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHCCCCCCCCCCCEECCHHHC
AHTHLELTHFPSWKIRKGIDYSPRTYVDWIIQVIKIRRALTRQEQELSVREGLRICLEAG
CCCEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TTSIGEILTDRSLLPLYADSGLGGRLFLEAIGHDPVRSAELISELGAAVASFPAGDLLPG
CCHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
LSPHAPHTVSEQLHQNVRRLAEEYNVPRIIHLAESREESDFFFDSTGKIAELLYSHVRWE
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHH
SYLPAPRRATATAWLDGLGVLNGAISAVHCVHLTPSDAETLAKRGVGIVLCPRSNEKLAV
HCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHCCCEEEEECCCCCCEEE
GRAPVAYLKKLGIPLALGTDSLASNDSLSLWDEMRYLLDLFPGVFTPSEALAMATIGSAR
CCCHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
QLALADRVGSIEKGKRADLLVMKLPGPQSTGEGLHEAVIGSGELLHVILSGRFTDRTEPR
HHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MELYAASYLVPISSPPVAGGALAVDNGRIVDTGTFAELRARYGCPVHDFPGCTILPGLVN
CCEEECEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHCCCCCCCCCCCEECCHHHC
AHTHLELTHFPSWKIRKGIDYSPRTYVDWIIQVIKIRRALTRQEQELSVREGLRICLEAG
CCCEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TTSIGEILTDRSLLPLYADSGLGGRLFLEAIGHDPVRSAELISELGAAVASFPAGDLLPG
CCHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
LSPHAPHTVSEQLHQNVRRLAEEYNVPRIIHLAESREESDFFFDSTGKIAELLYSHVRWE
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHH
SYLPAPRRATATAWLDGLGVLNGAISAVHCVHLTPSDAETLAKRGVGIVLCPRSNEKLAV
HCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHCCCEEEEECCCCCCEEE
GRAPVAYLKKLGIPLALGTDSLASNDSLSLWDEMRYLLDLFPGVFTPSEALAMATIGSAR
CCCHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
QLALADRVGSIEKGKRADLLVMKLPGPQSTGEGLHEAVIGSGELLHVILSGRFTDRTEPR
HHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA