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The map label for this gene is xerC [H]

Identifier: 39995600

GI number: 39995600

Start: 524995

End: 525879

Strand: Reverse

Name: xerC [H]

Synonym: GSU0492

Alternate gene names: 39995600

Gene position: 525879-524995 (Counterclockwise)

Preceding gene: 39995606

Following gene: 39995599

Centisome position: 13.79

GC content: 63.5

Gene sequence:

>885_bases
GTGGAGTTTGAAGTAACCACTTTCATCCGCTACCTGGAGAACGAGCGCGCCGTTTCCCCCCACACTCGCGCCGCCTATGA
GTCCGACCTTGCCCAATTCAGGGACTTCGTCCGGGGAGAACTGGGCGCCGGAGCCGGCGCGGCGGCCATAAGCCACCTCC
TGGTCCGGCGCTGGCTTGCCCAGCTCCATCAATCTCACGCCAGGAGCTCAATCGGCCGTAAACTGGCCGCAGTGCGTGCA
TTTTTTACCTACCTTGTCCGCACCGGAGCCCTGCCGCGCAACCCGGCAGAACTGGTCAGCACCCCCAAGCGCGAGAAGAA
GGTCCCGTTCCACCTGAACATCGATGAGGTGACCGCCCTGGTGGAGTCTCCCCGGGAACCCGGCGTCCTGAGCCTGCGCG
ACCGGGCCATTCTGGAAACCCTCTATTCCTGCGGCGTCAGGGTTTCGGAGCTGACCGGCCTCAATGTGGGGGGGATCGAC
CTGGCTGACGGCACGGTCCGTGTCCTCGGCAAGGGTGGCAAGGAACGGGTAGTTCCGATCGGGAGCCATGCCCGCCTCGC
CCTAAGCTCCTATCTGGCCGCCCGTAACCACCCTCCCCTGGAGGTCCCCCTTTTCACCAACGCTCGGGGAGGCCGGCTTA
CCGCCCGTAGCGTCCGGCGGGTGGTGGACAAGCATATCCTGAAAGTCGCCGCCATGAGGAAGATATCTCCCCACACCCTG
CGCCACACCTTTGCCACTCACCTCCTTGAGGGAGGAGCCGATCTGCGTGCCATCCAGGAACTGCTGGGACATGCCTCGCT
CTCAACCACCCAGAAATATACCCACGTGGGAATCGACCGTCTCATGGAAGTGTACGACAAGGCCCATCCCAAGGCACGCA
CCTGA

Upstream 100 bases:

>100_bases
GGAAGCATACCCCGATTCAGGGCGATACACAACCGGCCTTCGCACGGTCAATGGAATCTGTTATCATAGGCCGATCGCAC
GATCCTACCCGGAGGCAGCC

Downstream 100 bases:

>100_bases
GCCTCATCCGGATGCGCAAAGCCGCCACCGGACGGTGTTCAGCGCCCGCCGACAAAAAATCCTTGTCATTTCCACCAGTA
TCCCGTACAGTTACCGCTGA

Product: PfpI family intracellular peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MEFEVTTFIRYLENERAVSPHTRAAYESDLAQFRDFVRGELGAGAGAAAISHLLVRRWLAQLHQSHARSSIGRKLAAVRA
FFTYLVRTGALPRNPAELVSTPKREKKVPFHLNIDEVTALVESPREPGVLSLRDRAILETLYSCGVRVSELTGLNVGGID
LADGTVRVLGKGGKERVVPIGSHARLALSSYLAARNHPPLEVPLFTNARGGRLTARSVRRVVDKHILKVAAMRKISPHTL
RHTFATHLLEGGADLRAIQELLGHASLSTTQKYTHVGIDRLMEVYDKAHPKART

Sequences:

>Translated_294_residues
MEFEVTTFIRYLENERAVSPHTRAAYESDLAQFRDFVRGELGAGAGAAAISHLLVRRWLAQLHQSHARSSIGRKLAAVRA
FFTYLVRTGALPRNPAELVSTPKREKKVPFHLNIDEVTALVESPREPGVLSLRDRAILETLYSCGVRVSELTGLNVGGID
LADGTVRVLGKGGKERVVPIGSHARLALSSYLAARNHPPLEVPLFTNARGGRLTARSVRRVVDKHILKVAAMRKISPHTL
RHTFATHLLEGGADLRAIQELLGHASLSTTQKYTHVGIDRLMEVYDKAHPKART
>Mature_294_residues
MEFEVTTFIRYLENERAVSPHTRAAYESDLAQFRDFVRGELGAGAGAAAISHLLVRRWLAQLHQSHARSSIGRKLAAVRA
FFTYLVRTGALPRNPAELVSTPKREKKVPFHLNIDEVTALVESPREPGVLSLRDRAILETLYSCGVRVSELTGLNVGGID
LADGTVRVLGKGGKERVVPIGSHARLALSSYLAARNHPPLEVPLFTNARGGRLTARSVRRVVDKHILKVAAMRKISPHTL
RHTFATHLLEGGADLRAIQELLGHASLSTTQKYTHVGIDRLMEVYDKAHPKART

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=38.013698630137, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1789261, Length=297, Percent_Identity=39.0572390572391, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1790768, Length=181, Percent_Identity=27.6243093922652, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32417; Mature: 32417

Theoretical pI: Translated: 10.85; Mature: 10.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFEVTTFIRYLENERAVSPHTRAAYESDLAQFRDFVRGELGAGAGAAAISHLLVRRWLA
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QLHQSHARSSIGRKLAAVRAFFTYLVRTGALPRNPAELVSTPKREKKVPFHLNIDEVTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHCCCCEEECHHHHHHH
VESPREPGVLSLRDRAILETLYSCGVRVSELTGLNVGGIDLADGTVRVLGKGGKERVVPI
HHCCCCCCEEHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEECCCCEEEECCCCCCCEEEC
GSHARLALSSYLAARNHPPLEVPLFTNARGGRLTARSVRRVVDKHILKVAAMRKISPHTL
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RHTFATHLLEGGADLRAIQELLGHASLSTTQKYTHVGIDRLMEVYDKAHPKART
HHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEFEVTTFIRYLENERAVSPHTRAAYESDLAQFRDFVRGELGAGAGAAAISHLLVRRWLA
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QLHQSHARSSIGRKLAAVRAFFTYLVRTGALPRNPAELVSTPKREKKVPFHLNIDEVTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHCCCCEEECHHHHHHH
VESPREPGVLSLRDRAILETLYSCGVRVSELTGLNVGGIDLADGTVRVLGKGGKERVVPI
HHCCCCCCEEHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEECCCCEEEECCCCCCCEEEC
GSHARLALSSYLAARNHPPLEVPLFTNARGGRLTARSVRRVVDKHILKVAAMRKISPHTL
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RHTFATHLLEGGADLRAIQELLGHASLSTTQKYTHVGIDRLMEVYDKAHPKART
HHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA