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The map label for this gene is fabF [H]

Identifier: 39995567

GI number: 39995567

Start: 489577

End: 490602

Strand: Reverse

Name: fabF [H]

Synonym: GSU0459

Alternate gene names: 39995567

Gene position: 490602-489577 (Counterclockwise)

Preceding gene: 39995568

Following gene: 39995566

Centisome position: 12.86

GC content: 67.45

Gene sequence:

>1026_bases
ATGGACATAGCCGTCACCGGCCTCGCCGCCATCTCCGCCGCCGGGGTGGGAATCGAACCGTTGCGGGAAACGGTGGCACA
GCGTCAATGCCGCCTCACCCCCGTCCCCGTTGAAGTCCTCGGTGAAGACGGATATCTCTGGGGCAAGGCGGATGGCTTCA
GGGCCGCCGATTTCATGCCTCCCCTCAAGGCCCGAAAGTTCGACCGGTGCAGCCTTCTGGCCACTGTGGCCGCAGGCATG
GCCCTGGCCGATGCCGGCATCGACCCGAAGGGGGGCGATCCCACACGCATCGGCATCGCCCTGGGCTGCGGCTTCGGCGG
CATCGCCAATTCCGTGGAGTTTCTGGGCGGCTACTTCTCCAGGGGCGTGGAAGGGCTCGTGCCCATGCTCTTCCCCAATA
CCGTTGCCAATGCCGCCGCCAGCAACGCCTCCATCGAGCATGGCCTCAAGGGGCCCAACGTGACCCAAGTACAGCGCTTC
TGCTCCGCAGAGGCTGCTATCCAGATGGCCTGTCGTTTCCTGGAGGAAGGGCGGGCCGACGTGATGCTGGCGGGCGGAGT
GGATGAGCTGACCCCGCTGATGATGGCCGGCTTCCAGGCCGTGGGCCAGTTGCGGACCTATGCCCGCTCCTTCAGCGAGG
GGTGCGGCATCCTGGTCCTTGAGCGGCGAGACCATGCGGAACGACGCGCCGCCAGGCTGCGGGGCCGAATCACGGGACTG
CGAACGGTGGGCATGCTGCCCGCCGGCCGGGAACAGGAGACGGTCGACCGACTCATGCCACCCGCGGCACCGGCCCTGGT
GTCGCTCTCGGGAATCGCAGCCGACATCACAGCCCTCATCGCTCCACTCCCTGCCGTGCCGACTTTGGAATCGGGCAACC
TTATCGGACGATCCCTGGCCATGGGGGGGCTTGCCCTGGCCTCGCTCCTGCTGGTCCTCCCCGAAGGTGCCCGGGGGCTC
CACCTGGCAGCGTCGCCCGAAGGACCGTACCACGCCATCGACGTCACCGGGGGTATGCGTGCATAG

Upstream 100 bases:

>100_bases
ACGGCCCACGGGAGAGCTCGGCAACCGTCGCCCTCTCCAATTCCTTTGCCTTTGGCGGCAACGTTACCTCGGTGGTGATC
GGACGATGAGCATCCCGTCA

Downstream 100 bases:

>100_bases
CCCCGCTCCGTGGGACTTCCTGCCCCATCGCTATCCTTTTCTCGTCCTCGACCGTATAATCGCCAAGGAGCCCGGCCGAT
CGGCCACGGCCCTCATGCGG

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MDIAVTGLAAISAAGVGIEPLRETVAQRQCRLTPVPVEVLGEDGYLWGKADGFRAADFMPPLKARKFDRCSLLATVAAGM
ALADAGIDPKGGDPTRIGIALGCGFGGIANSVEFLGGYFSRGVEGLVPMLFPNTVANAAASNASIEHGLKGPNVTQVQRF
CSAEAAIQMACRFLEEGRADVMLAGGVDELTPLMMAGFQAVGQLRTYARSFSEGCGILVLERRDHAERRAARLRGRITGL
RTVGMLPAGREQETVDRLMPPAAPALVSLSGIAADITALIAPLPAVPTLESGNLIGRSLAMGGLALASLLLVLPEGARGL
HLAASPEGPYHAIDVTGGMRA

Sequences:

>Translated_341_residues
MDIAVTGLAAISAAGVGIEPLRETVAQRQCRLTPVPVEVLGEDGYLWGKADGFRAADFMPPLKARKFDRCSLLATVAAGM
ALADAGIDPKGGDPTRIGIALGCGFGGIANSVEFLGGYFSRGVEGLVPMLFPNTVANAAASNASIEHGLKGPNVTQVQRF
CSAEAAIQMACRFLEEGRADVMLAGGVDELTPLMMAGFQAVGQLRTYARSFSEGCGILVLERRDHAERRAARLRGRITGL
RTVGMLPAGREQETVDRLMPPAAPALVSLSGIAADITALIAPLPAVPTLESGNLIGRSLAMGGLALASLLLVLPEGARGL
HLAASPEGPYHAIDVTGGMRA
>Mature_341_residues
MDIAVTGLAAISAAGVGIEPLRETVAQRQCRLTPVPVEVLGEDGYLWGKADGFRAADFMPPLKARKFDRCSLLATVAAGM
ALADAGIDPKGGDPTRIGIALGCGFGGIANSVEFLGGYFSRGVEGLVPMLFPNTVANAAASNASIEHGLKGPNVTQVQRF
CSAEAAIQMACRFLEEGRADVMLAGGVDELTPLMMAGFQAVGQLRTYARSFSEGCGILVLERRDHAERRAARLRGRITGL
RTVGMLPAGREQETVDRLMPPAAPALVSLSGIAADITALIAPLPAVPTLESGNLIGRSLAMGGLALASLLLVLPEGARGL
HLAASPEGPYHAIDVTGGMRA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=205, Percent_Identity=29.7560975609756, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1787337, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 35322; Mature: 35322

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIAVTGLAAISAAGVGIEPLRETVAQRQCRLTPVPVEVLGEDGYLWGKADGFRAADFMP
CCEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCEEEECCCCCCCCCCCC
PLKARKFDRCSLLATVAAGMALADAGIDPKGGDPTRIGIALGCGFGGIANSVEFLGGYFS
CHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
RGVEGLVPMLFPNTVANAAASNASIEHGLKGPNVTQVQRFCSAEAAIQMACRFLEEGRAD
CCHHHHHHHHCCHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VMLAGGVDELTPLMMAGFQAVGQLRTYARSFSEGCGILVLERRDHAERRAARLRGRITGL
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
RTVGMLPAGREQETVDRLMPPAAPALVSLSGIAADITALIAPLPAVPTLESGNLIGRSLA
HHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
MGGLALASLLLVLPEGARGLHLAASPEGPYHAIDVTGGMRA
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCCCC
>Mature Secondary Structure
MDIAVTGLAAISAAGVGIEPLRETVAQRQCRLTPVPVEVLGEDGYLWGKADGFRAADFMP
CCEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCEEEECCCCCCCCCCCC
PLKARKFDRCSLLATVAAGMALADAGIDPKGGDPTRIGIALGCGFGGIANSVEFLGGYFS
CHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
RGVEGLVPMLFPNTVANAAASNASIEHGLKGPNVTQVQRFCSAEAAIQMACRFLEEGRAD
CCHHHHHHHHCCHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VMLAGGVDELTPLMMAGFQAVGQLRTYARSFSEGCGILVLERRDHAERRAARLRGRITGL
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
RTVGMLPAGREQETVDRLMPPAAPALVSLSGIAADITALIAPLPAVPTLESGNLIGRSLA
HHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
MGGLALASLLLVLPEGARGLHLAASPEGPYHAIDVTGGMRA
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]