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The map label for this gene is fabD [H]

Identifier: 39995350

GI number: 39995350

Start: 247661

End: 248503

Strand: Reverse

Name: fabD [H]

Synonym: GSU0240

Alternate gene names: 39995350

Gene position: 248503-247661 (Counterclockwise)

Preceding gene: 39995351

Following gene: 39995349

Centisome position: 6.52

GC content: 69.16

Gene sequence:

>843_bases
ATGATCTGCTTCATGTTTCCCGGACAACCCCTCGCGCCCCCGGTCGAATTCCCGGAGGACGCGGATTTCGAGGCCATTGC
CCTTTTGACGCGGCAGCGGGCCTCCTTTGACCTGCACACCTTTTCCTGGACCGGCGAGCCGTCCAGCGATACCGTGGCAC
TCCAGGCCTACGGCGTGGCCATGGGGCTCTACCGGACCCGCCGGCTCAGGGCCGAGGGGATCGCGCCCCGGCTCATCGCC
GAGCACAGCATGGGGATCTACCCCGCCCTGGCCGCGGCCGGCGCCCTGGATGAGGGGGACGCCCTGGAGCTCGCCGTCCG
CCTCGGCAGGACCATGGCCGCCATGGGGAGACAACGGACCTACGCCCTCGGCTGCATGGTGGGGCTCACCCTGGAACCCC
TCCTGGTCATTGCCGAGAACAACGGCGTGTACCTTGCCAATCACAATACGTCCCGCCACTTTCTCCTGGCCGGCGAACGG
GGGGCCATGGAGGACGCCTGCGCCGAGGCCCTGGCCCGCGGCGCCTTCTCGGCCAGGCTCTTTCCGTGCGACGCCCCGCT
CCACACCCCGCTCATGGCGGAGGTGGCAGAAGAGCTTGCTGCCGTTGCCGGCGATTACCGCTACCGGGAGCCGTCCGTCC
CCCTGGTGGACCACATCGACCAGGACTTCCTGGCCGCCGCAGACCTGCCGGTGTTCATGGTCCGGGACCTCATGGAGCCG
GTCCGGTGGGAGCGCACCTACCGCGCCCTGCGCGCCGCCGGCGTCGACCGTCTTTACGAGGTGGGGGCGGGTGATTCCCT
CCGCAAGTACAACCGGTGGATCGAAAGCGAGCGGGGGAGGTAG

Upstream 100 bases:

>100_bases
GCATCGGCAAGCTGCACCGCTCGGTACAGGTCTTCGGCCCCATGAACCTGGGGTTCCGCAGCGCCATCCGAAAATCCGAC
AAAACGAAAGCCTCCTGACC

Downstream 100 bases:

>100_bases
CATGCGGGAACACGAGACACCACTCACCGTCCGTTTCAACGAGGTTGACTCCTACGGCGTTGCCTGGCACGGCCACTACG
TGGCCTGGCTGGAGGTGGGG

Product: malonyl CoA-ACP transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MICFMFPGQPLAPPVEFPEDADFEAIALLTRQRASFDLHTFSWTGEPSSDTVALQAYGVAMGLYRTRRLRAEGIAPRLIA
EHSMGIYPALAAAGALDEGDALELAVRLGRTMAAMGRQRTYALGCMVGLTLEPLLVIAENNGVYLANHNTSRHFLLAGER
GAMEDACAEALARGAFSARLFPCDAPLHTPLMAEVAEELAAVAGDYRYREPSVPLVDHIDQDFLAAADLPVFMVRDLMEP
VRWERTYRALRAAGVDRLYEVGAGDSLRKYNRWIESERGR

Sequences:

>Translated_280_residues
MICFMFPGQPLAPPVEFPEDADFEAIALLTRQRASFDLHTFSWTGEPSSDTVALQAYGVAMGLYRTRRLRAEGIAPRLIA
EHSMGIYPALAAAGALDEGDALELAVRLGRTMAAMGRQRTYALGCMVGLTLEPLLVIAENNGVYLANHNTSRHFLLAGER
GAMEDACAEALARGAFSARLFPCDAPLHTPLMAEVAEELAAVAGDYRYREPSVPLVDHIDQDFLAAADLPVFMVRDLMEP
VRWERTYRALRAAGVDRLYEVGAGDSLRKYNRWIESERGR
>Mature_280_residues
MICFMFPGQPLAPPVEFPEDADFEAIALLTRQRASFDLHTFSWTGEPSSDTVALQAYGVAMGLYRTRRLRAEGIAPRLIA
EHSMGIYPALAAAGALDEGDALELAVRLGRTMAAMGRQRTYALGCMVGLTLEPLLVIAENNGVYLANHNTSRHFLLAGER
GAMEDACAEALARGAFSARLFPCDAPLHTPLMAEVAEELAAVAGDYRYREPSVPLVDHIDQDFLAAADLPVFMVRDLMEP
VRWERTYRALRAAGVDRLYEVGAGDSLRKYNRWIESERGR

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Escherichia coli, GI1787334, Length=251, Percent_Identity=31.0756972111554, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 30833; Mature: 30833

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICFMFPGQPLAPPVEFPEDADFEAIALLTRQRASFDLHTFSWTGEPSSDTVALQAYGVA
CEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEHHHHH
MGLYRTRRLRAEGIAPRLIAEHSMGIYPALAAAGALDEGDALELAVRLGRTMAAMGRQRT
HHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHH
YALGCMVGLTLEPLLVIAENNGVYLANHNTSRHFLLAGERGAMEDACAEALARGAFSARL
HHHHHHHCCCCCEEEEEEECCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEE
FPCDAPLHTPLMAEVAEELAAVAGDYRYREPSVPLVDHIDQDFLAAADLPVFMVRDLMEP
EECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHCCCHHHHHHHHHHH
VRWERTYRALRAAGVDRLYEVGAGDSLRKYNRWIESERGR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MICFMFPGQPLAPPVEFPEDADFEAIALLTRQRASFDLHTFSWTGEPSSDTVALQAYGVA
CEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEHHHHH
MGLYRTRRLRAEGIAPRLIAEHSMGIYPALAAAGALDEGDALELAVRLGRTMAAMGRQRT
HHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHH
YALGCMVGLTLEPLLVIAENNGVYLANHNTSRHFLLAGERGAMEDACAEALARGAFSARL
HHHHHHHCCCCCEEEEEEECCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEE
FPCDAPLHTPLMAEVAEELAAVAGDYRYREPSVPLVDHIDQDFLAAADLPVFMVRDLMEP
EECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHCCCHHHHHHHHHHH
VRWERTYRALRAAGVDRLYEVGAGDSLRKYNRWIESERGR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]