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The map label for this gene is rnz [H]

Identifier: 39995245

GI number: 39995245

Start: 148677

End: 149777

Strand: Reverse

Name: rnz [H]

Synonym: GSU0134

Alternate gene names: 39995245

Gene position: 149777-148677 (Counterclockwise)

Preceding gene: 39995246

Following gene: 39995243

Centisome position: 3.93

GC content: 64.21

Gene sequence:

>1101_bases
ATGAAGAGCCGCCTCCCCTTCCGTTACCTGGAGCCCACCTTCTGCGCGGGGCTCCTGGACGACCCGGTCCTCCTGGTGAA
CGTCCGGCCCCTGGGGCGCTCGATCCTGGTGGACTGCGGCCAGATTCACCATCTGGCCAAGCGGGTCCTGAAATCCATCG
ATGCCGTCTTCGTCTCCCATGCCCATATGGATCACTTCATGGGGCTGGACACCCTGGTCCGCCACATTCACGTCTCCCCG
CGGACGGTCGAACTCTTCGGCCCGCCGGGGATCGCCCGGAAAGTGGCTGCAAAGCTGGCCGGTTACGACTGGAACCTGAC
CGAATCCTACTGGTGCACCTTCCGGGTGAGCGAAGTCCATCCCGAGCGTATTGTCCGGTTCACGTTCCCCGGCTCCGAAG
GATTTCCCTGCCTGCCCGAGGAAGAGACAACGCGGGAGGGGACCGAGATCTTCCGCAACGACTTTCTCGCGGTCGACGCG
GATCTCTGCGACCATAACACCCTGCCGACCCTGGTCTTTCGCATCACCGAACGTCCCACCTTCTGGATCGACGAGGCAAA
AGTCGATCAGGAGGGTCTTGTGCCGGGGGAATGGCTGCGGGAGCTGAAGCACCGCTTCTATCGCGGCAGACTGGATGGGA
AGACGATCACCGTGCCCGTGCGCACGGCCGGCGACACGGTGGCACAACGGATCCGGGAAGGACGGGAGCTGTTCGAGGCA
ATCCGGAGGAGCCAGGAGCCTGCCAGCATTGGCTACCTCACCGACATCGGCGCCGGCGACACCAACCTGGCGACGGTGCG
GCGATTACTTGCCGGTGTCACGCTCCTTGCCTGCGAGTGCTCGTTTCTAGCAGCCGACGTGGCCAAGGCCCGCACCTCCC
ACCACCTCTGCACGGCGGATGTATCGGCCCTCGCCCGGGAGATCCGTCCCGGCTGGCTCCTTCCCATGCATCTTTCCAAG
AGCTACAATACAAAGGGCCACCTCCTCTACCGGGAGCTGACCCTTGCGCCGGAAACCCGGCTGATCCGCCTGCCCGAGCA
TCTTACCCCCCGGCCGCTTCTGCCGGGGGAGTTTCCGGGCCTCTGGAAAATCGCGGAATAG

Upstream 100 bases:

>100_bases
GCGGGTCCTCAAGAGAGGATAGCCTGTTTCCGTGATACACTGAAAAGGCCTGCCGGGTGGCGGGCCTTTTTTCGTATCAG
CCGCATTCGCGAGGCATCCT

Downstream 100 bases:

>100_bases
AGGGGGGCTTACTCCCCTGCCAGCCACCCTTCGATCCGAGCCAGTTCTTCGCCCCATCCGGCACCCAGACGCACCGTGAG
GAATTCGCCGTACAGGCTGT

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MKSRLPFRYLEPTFCAGLLDDPVLLVNVRPLGRSILVDCGQIHHLAKRVLKSIDAVFVSHAHMDHFMGLDTLVRHIHVSP
RTVELFGPPGIARKVAAKLAGYDWNLTESYWCTFRVSEVHPERIVRFTFPGSEGFPCLPEEETTREGTEIFRNDFLAVDA
DLCDHNTLPTLVFRITERPTFWIDEAKVDQEGLVPGEWLRELKHRFYRGRLDGKTITVPVRTAGDTVAQRIREGRELFEA
IRRSQEPASIGYLTDIGAGDTNLATVRRLLAGVTLLACECSFLAADVAKARTSHHLCTADVSALAREIRPGWLLPMHLSK
SYNTKGHLLYRELTLAPETRLIRLPEHLTPRPLLPGEFPGLWKIAE

Sequences:

>Translated_366_residues
MKSRLPFRYLEPTFCAGLLDDPVLLVNVRPLGRSILVDCGQIHHLAKRVLKSIDAVFVSHAHMDHFMGLDTLVRHIHVSP
RTVELFGPPGIARKVAAKLAGYDWNLTESYWCTFRVSEVHPERIVRFTFPGSEGFPCLPEEETTREGTEIFRNDFLAVDA
DLCDHNTLPTLVFRITERPTFWIDEAKVDQEGLVPGEWLRELKHRFYRGRLDGKTITVPVRTAGDTVAQRIREGRELFEA
IRRSQEPASIGYLTDIGAGDTNLATVRRLLAGVTLLACECSFLAADVAKARTSHHLCTADVSALAREIRPGWLLPMHLSK
SYNTKGHLLYRELTLAPETRLIRLPEHLTPRPLLPGEFPGLWKIAE
>Mature_366_residues
MKSRLPFRYLEPTFCAGLLDDPVLLVNVRPLGRSILVDCGQIHHLAKRVLKSIDAVFVSHAHMDHFMGLDTLVRHIHVSP
RTVELFGPPGIARKVAAKLAGYDWNLTESYWCTFRVSEVHPERIVRFTFPGSEGFPCLPEEETTREGTEIFRNDFLAVDA
DLCDHNTLPTLVFRITERPTFWIDEAKVDQEGLVPGEWLRELKHRFYRGRLDGKTITVPVRTAGDTVAQRIREGRELFEA
IRRSQEPASIGYLTDIGAGDTNLATVRRLLAGVTLLACECSFLAADVAKARTSHHLCTADVSALAREIRPGWLLPMHLSK
SYNTKGHLLYRELTLAPETRLIRLPEHLTPRPLLPGEFPGLWKIAE

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 41352; Mature: 41352

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRLPFRYLEPTFCAGLLDDPVLLVNVRPLGRSILVDCGQIHHLAKRVLKSIDAVFVSH
CCCCCCCHHCCHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHMDHFMGLDTLVRHIHVSPRTVELFGPPGIARKVAAKLAGYDWNLTESYWCTFRVSEVH
HHHHHHHCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCC
PERIVRFTFPGSEGFPCLPEEETTREGTEIFRNDFLAVDADLCDHNTLPTLVFRITERPT
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCE
FWIDEAKVDQEGLVPGEWLRELKHRFYRGRLDGKTITVPVRTAGDTVAQRIREGRELFEA
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
IRRSQEPASIGYLTDIGAGDTNLATVRRLLAGVTLLACECSFLAADVAKARTSHHLCTAD
HHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VSALAREIRPGWLLPMHLSKSYNTKGHLLYRELTLAPETRLIRLPEHLTPRPLLPGEFPG
HHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCC
LWKIAE
CEEECC
>Mature Secondary Structure
MKSRLPFRYLEPTFCAGLLDDPVLLVNVRPLGRSILVDCGQIHHLAKRVLKSIDAVFVSH
CCCCCCCHHCCHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHMDHFMGLDTLVRHIHVSPRTVELFGPPGIARKVAAKLAGYDWNLTESYWCTFRVSEVH
HHHHHHHCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCC
PERIVRFTFPGSEGFPCLPEEETTREGTEIFRNDFLAVDADLCDHNTLPTLVFRITERPT
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCE
FWIDEAKVDQEGLVPGEWLRELKHRFYRGRLDGKTITVPVRTAGDTVAQRIREGRELFEA
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
IRRSQEPASIGYLTDIGAGDTNLATVRRLLAGVTLLACECSFLAADVAKARTSHHLCTAD
HHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VSALAREIRPGWLLPMHLSKSYNTKGHLLYRELTLAPETRLIRLPEHLTPRPLLPGEFPG
HHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCC
LWKIAE
CEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]