Click here to switch to the map view.

The map label for this gene is narL [H]

Identifier: 38637927

GI number: 38637927

Start: 281969

End: 282631

Strand: Direct

Name: narL [H]

Synonym: PHG266

Alternate gene names: 38637927

Gene position: 281969-282631 (Clockwise)

Preceding gene: 38637926

Following gene: 38637929

Centisome position: 62.36

GC content: 65.91

Gene sequence:

>663_bases
ATGACCATCTGCATCCTGCTGATCGATGACCACACGCTGTTTCGCTCCGGCATCCGGGCCCTGCTGCAGCGGCAGGCCGA
TTTCGAAATCGTCGACGAGGCCGCCGACGGCGTGGAGGACATCAAGCGCGCCAAGCAGCGCCGGCCCGATGTCATCCTGC
TGGACCTGAACATGCCCGGCCTGTCCGGGCTGGAAGCGCTCCAGCTGCTGGTGGAAGATCTTCCCGATAGCGCAGTGATC
GTGCTGACCGTGTCCGAAGAGGCCGAGGAGCTTGCCATCGCACTGCGCAGCGGCGCGCGCGGCTACCTGCTTAAGAACAT
CGAGACCGAGGCCCTGACCAGCGCCATCCGCCGTGCTGCGGCCGGTGAACCCGTGATCTCCGAAAGCATGACCGCCAAGC
TCGTCGCGCAGTTCCGCGCCCCCGCGCCCGCCGCTGTCGCTGTTCCTCAGCAGGTCGACACGGCGCGGCTCACGGTACGC
GAGCGCGAGATCGTTCAGGAACTGGCCCGCGGCGAGAGCAACAAGGAAATCGCGCGCACCCTGGGCGTGGCTGCGAGCAC
CGTGAAGATCCACGTGCAGAACATCCTGAAGAAGCTTAACCTCGCCAGCCGCGTGCAGGTCGCCGTCTACGCAGTCGAGC
ACCGCCTGACCGAAACTGGCTGA

Upstream 100 bases:

>100_bases
ACAGCCAGCCGGGGGCAGGCGTGCGCATCGCACTGCTGTTGCCGCGCGGCGAACAACAACCCGACGCCATGGCTGCCAGC
CAACTCCAAAATACCTTCCC

Downstream 100 bases:

>100_bases
ACCGTCCGGCGCCATTGCGCGCCGCCCCGCCGCGCGGCGTCCTCATCCTGTTCCTGGACCAGGATCAGTCCACCTTCGGC
GCGTCTTCCCATCCGCCTGG

Product: nitrate/nitrite response regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTICILLIDDHTLFRSGIRALLQRQADFEIVDEAADGVEDIKRAKQRRPDVILLDLNMPGLSGLEALQLLVEDLPDSAVI
VLTVSEEAEELAIALRSGARGYLLKNIETEALTSAIRRAAAGEPVISESMTAKLVAQFRAPAPAAVAVPQQVDTARLTVR
EREIVQELARGESNKEIARTLGVAASTVKIHVQNILKKLNLASRVQVAVYAVEHRLTETG

Sequences:

>Translated_220_residues
MTICILLIDDHTLFRSGIRALLQRQADFEIVDEAADGVEDIKRAKQRRPDVILLDLNMPGLSGLEALQLLVEDLPDSAVI
VLTVSEEAEELAIALRSGARGYLLKNIETEALTSAIRRAAAGEPVISESMTAKLVAQFRAPAPAAVAVPQQVDTARLTVR
EREIVQELARGESNKEIARTLGVAASTVKIHVQNILKKLNLASRVQVAVYAVEHRLTETG
>Mature_219_residues
TICILLIDDHTLFRSGIRALLQRQADFEIVDEAADGVEDIKRAKQRRPDVILLDLNMPGLSGLEALQLLVEDLPDSAVIV
LTVSEEAEELAIALRSGARGYLLKNIETEALTSAIRRAAAGEPVISESMTAKLVAQFRAPAPAAVAVPQQVDTARLTVRE
REIVQELARGESNKEIARTLGVAASTVKIHVQNILKKLNLASRVQVAVYAVEHRLTETG

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787473, Length=213, Percent_Identity=44.6009389671362, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788521, Length=214, Percent_Identity=40.6542056074766, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788222, Length=218, Percent_Identity=30.7339449541284, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790102, Length=206, Percent_Identity=33.0097087378641, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786747, Length=212, Percent_Identity=26.8867924528302, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788712, Length=211, Percent_Identity=22.7488151658768, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082052, Length=117, Percent_Identity=39.3162393162393, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789937, Length=205, Percent_Identity=23.9024390243902, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23917; Mature: 23786

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTICILLIDDHTLFRSGIRALLQRQADFEIVDEAADGVEDIKRAKQRRPDVILLDLNMPG
CEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCC
LSGLEALQLLVEDLPDSAVIVLTVSEEAEELAIALRSGARGYLLKNIETEALTSAIRRAA
CCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHH
AGEPVISESMTAKLVAQFRAPAPAAVAVPQQVDTARLTVREREIVQELARGESNKEIART
CCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
LGVAASTVKIHVQNILKKLNLASRVQVAVYAVEHRLTETG
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TICILLIDDHTLFRSGIRALLQRQADFEIVDEAADGVEDIKRAKQRRPDVILLDLNMPG
EEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCC
LSGLEALQLLVEDLPDSAVIVLTVSEEAEELAIALRSGARGYLLKNIETEALTSAIRRAA
CCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHH
AGEPVISESMTAKLVAQFRAPAPAAVAVPQQVDTARLTVREREIVQELARGESNKEIART
CCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
LGVAASTVKIHVQNILKKLNLASRVQVAVYAVEHRLTETG
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]