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The map label for this gene is lldR [H]

Identifier: 38234639

GI number: 38234639

Start: 2133153

End: 2133851

Strand: Reverse

Name: lldR [H]

Synonym: DIP2081

Alternate gene names: 38234639

Gene position: 2133851-2133153 (Counterclockwise)

Preceding gene: 38234643

Following gene: 38234638

Centisome position: 85.74

GC content: 53.36

Gene sequence:

>699_bases
ATGCGTAAGGACCGTGTCACTCAGGGCGTTGATCGCATAATGCAAGCTATTGCCGACAAAGAATTCGAGCTAGGACAAGC
GATTCCGGGTGAAGCGAAGCTAGCGGAGTTTCTTGACGTTTCGCGCCCGACAATGCGTGAGGTCGTCCGCACACTTGCAG
ATCGTGGAGTGCTGGAAGTAGTCCATGGCCGAGGTACTTTCGTCGCTCCGCTTGATCATTGGAGTGATGTGCGCAGCCGC
GTCGACTTCATTTCTCGAACATTATCTCCCGGTGAAGTCGGTTTCCACCTCACCGAGGTGCGTCGAATGATCGAAGTTGG
CTCTTGCGGTCATGCAGCAGCGCGCGCTGAGGATTGTGATTTAGATCGAATGCAGACGGCACTTGATGCTTATGACGCGG
CCTTGGAAGCTCATGATGTCGCTGGCATAGCAAAATCTGACGTTGAATTCCACAACGCAATTTTTGAAGCCACCAAGAAC
CCGGTCGTTACTGCGCTTATGATCCCTCTCGAGGGGGAGCTGGCGGCATCGCGCCTGCGGACAAGTGCAGTATCGGAGGT
CGCCGAACGTGCGCAAGAACATCATCGCCGAATCTATTCTGCAATCAAGGCAAGTGATGAAGAAGGAGCAAAGAACGCGA
TGCGCGCGCATATGTCGCAGACTTTTGATGATTTGCAGCGGTTCGTGGGAGAATATTAA

Upstream 100 bases:

>100_bases
GAAATCTAGGTCCTCTGAGGAGCTGTTTGTATGATGGATAAGTAGTTGTTGTCATTGGACGCAAACCTTAGAGGACTGCA
GTGTAGGGGAGATTTTTATC

Downstream 100 bases:

>100_bases
CTCATTTGGGGGCCACCATTGGCCGTTTGCAAGAGGAACGTGTGTAACGACAATCGGCTGTTTACGTAGTGTTTCACCGT
ACTTAACCCTTTGATGCAGC

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MRKDRVTQGVDRIMQAIADKEFELGQAIPGEAKLAEFLDVSRPTMREVVRTLADRGVLEVVHGRGTFVAPLDHWSDVRSR
VDFISRTLSPGEVGFHLTEVRRMIEVGSCGHAAARAEDCDLDRMQTALDAYDAALEAHDVAGIAKSDVEFHNAIFEATKN
PVVTALMIPLEGELAASRLRTSAVSEVAERAQEHHRRIYSAIKASDEEGAKNAMRAHMSQTFDDLQRFVGEY

Sequences:

>Translated_232_residues
MRKDRVTQGVDRIMQAIADKEFELGQAIPGEAKLAEFLDVSRPTMREVVRTLADRGVLEVVHGRGTFVAPLDHWSDVRSR
VDFISRTLSPGEVGFHLTEVRRMIEVGSCGHAAARAEDCDLDRMQTALDAYDAALEAHDVAGIAKSDVEFHNAIFEATKN
PVVTALMIPLEGELAASRLRTSAVSEVAERAQEHHRRIYSAIKASDEEGAKNAMRAHMSQTFDDLQRFVGEY
>Mature_232_residues
MRKDRVTQGVDRIMQAIADKEFELGQAIPGEAKLAEFLDVSRPTMREVVRTLADRGVLEVVHGRGTFVAPLDHWSDVRSR
VDFISRTLSPGEVGFHLTEVRRMIEVGSCGHAAARAEDCDLDRMQTALDAYDAALEAHDVAGIAKSDVEFHNAIFEATKN
PVVTALMIPLEGELAASRLRTSAVSEVAERAQEHHRRIYSAIKASDEEGAKNAMRAHMSQTFDDLQRFVGEY

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=223, Percent_Identity=33.6322869955157, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI48994955, Length=215, Percent_Identity=29.3023255813954, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1789621, Length=216, Percent_Identity=27.3148148148148, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786303, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790780, Length=225, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789353, Length=232, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25717; Mature: 25717

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKDRVTQGVDRIMQAIADKEFELGQAIPGEAKLAEFLDVSRPTMREVVRTLADRGVLEV
CCCHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
VHGRGTFVAPLDHWSDVRSRVDFISRTLSPGEVGFHLTEVRRMIEVGSCGHAAARAEDCD
HHCCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCC
LDRMQTALDAYDAALEAHDVAGIAKSDVEFHNAIFEATKNPVVTALMIPLEGELAASRLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
TSAVSEVAERAQEHHRRIYSAIKASDEEGAKNAMRAHMSQTFDDLQRFVGEY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKDRVTQGVDRIMQAIADKEFELGQAIPGEAKLAEFLDVSRPTMREVVRTLADRGVLEV
CCCHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
VHGRGTFVAPLDHWSDVRSRVDFISRTLSPGEVGFHLTEVRRMIEVGSCGHAAARAEDCD
HHCCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCC
LDRMQTALDAYDAALEAHDVAGIAKSDVEFHNAIFEATKNPVVTALMIPLEGELAASRLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
TSAVSEVAERAQEHHRRIYSAIKASDEEGAKNAMRAHMSQTFDDLQRFVGEY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]