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The map label for this gene is folB [H]

Identifier: 38234562

GI number: 38234562

Start: 2046779

End: 2047144

Strand: Reverse

Name: folB [H]

Synonym: DIP1998

Alternate gene names: 38234562

Gene position: 2047144-2046779 (Counterclockwise)

Preceding gene: 38234563

Following gene: 38234561

Centisome position: 82.26

GC content: 53.83

Gene sequence:

>366_bases
ATGGCTGATCGTATCGAACTTAAAGGCTTGCACTGCTTTGGCTACCACGGGGTTTTCGAACACGAAAAACGCGAAGGCCA
AGACTTCATTATCGACGTCACCTGCTGGCTGGATCTGCGCCCCGCAGCAGCCTCAGATGACCTGACACACACCGTTCACT
ACGGGGAATTAGCCCAGCTAGCTCACGATATTGTGACAGGTCCACCACGTGATCTCATCGAGGCCGTAGCCGGAGAGATC
GCCGAATCCGCGATGGCAACATTCCCGCTTATCACAGCCATTGAGGTCACCGTGCATAAGCCACAGGCACCGATTCCTCT
AGAATTTACCGATGTAGCAGTAGTTGCCCGTAGGTCAAGGAGGTAA

Upstream 100 bases:

>100_bases
CGATCGCCGCACACATGGGAGCATGGTGCGTGCGCGTCCACGAAGTAGCAGTTTCCCGAGACGCGGTCGACGTTGCGGCC
CTGTGGAATGCGTGATTGTT

Downstream 100 bases:

>100_bases
CCGGCGAATATGCGCGCAGTGCTTTCTATTGGTTCGAATATGGATGACCGCTATGCCTTGCTGCGAACGGTTGTCGAAGA
ATTCGCAGGGCAGATCGTGG

Product: putative dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MADRIELKGLHCFGYHGVFEHEKREGQDFIIDVTCWLDLRPAAASDDLTHTVHYGELAQLAHDIVTGPPRDLIEAVAGEI
AESAMATFPLITAIEVTVHKPQAPIPLEFTDVAVVARRSRR

Sequences:

>Translated_121_residues
MADRIELKGLHCFGYHGVFEHEKREGQDFIIDVTCWLDLRPAAASDDLTHTVHYGELAQLAHDIVTGPPRDLIEAVAGEI
AESAMATFPLITAIEVTVHKPQAPIPLEFTDVAVVARRSRR
>Mature_120_residues
ADRIELKGLHCFGYHGVFEHEKREGQDFIIDVTCWLDLRPAAASDDLTHTVHYGELAQLAHDIVTGPPRDLIEAVAGEIA
ESAMATFPLITAIEVTVHKPQAPIPLEFTDVAVVARRSRR

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13397; Mature: 13266

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRIELKGLHCFGYHGVFEHEKREGQDFIIDVTCWLDLRPAAASDDLTHTVHYGELAQL
CCCCEEECEEEEECCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCEEEECHHHHHHH
AHDIVTGPPRDLIEAVAGEIAESAMATFPLITAIEVTVHKPQAPIPLEFTDVAVVARRSR
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCHHHHHHHHHHCC
R
C
>Mature Secondary Structure 
ADRIELKGLHCFGYHGVFEHEKREGQDFIIDVTCWLDLRPAAASDDLTHTVHYGELAQL
CCCEEECEEEEECCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCEEEECHHHHHHH
AHDIVTGPPRDLIEAVAGEIAESAMATFPLITAIEVTVHKPQAPIPLEFTDVAVVARRSR
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCHHHHHHHHHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]