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The map label for this gene is ftsZ [H]

Identifier: 38234170

GI number: 38234170

Start: 1623908

End: 1625143

Strand: Reverse

Name: ftsZ [H]

Synonym: DIP1595

Alternate gene names: 38234170

Gene position: 1625143-1623908 (Counterclockwise)

Preceding gene: 38234171

Following gene: 38234169

Centisome position: 65.3

GC content: 52.99

Gene sequence:

>1236_bases
ATGACTTCCCCAGATAATTACCTCGCCGTAATCAAGGTTGTTGGTGTCGGTGGCGGCGGTGTAAACGCTGTTAACCGAAT
GATCGAAGAGGGGCTAAAAGGTGTTGAGTTTATTGCGGTCAACACCGACTCTCAGGCATTGATGTTCTCTGATGCCGATG
TCAAGCTCGACATTGGACGAGAAGCTACTCGCGGCCTTGGTGCTGGTGCAAACCCTGAAGTTGGACGCGCATCAGCAGAA
GATCACAAAAACGAGATCGAAGAAACCCTTAAAGGGGCGGACATGGTCTTCGTTACTGCCGGTGAGGGCGGCGGTACTGG
TACCGGTGCAGCACCAGTCGTTGCGGGAATCGCTAAACGCTTGGGTGCACTTACCGTCGGCGTGGTTACGCGTCCATTCA
AGTTTGAGGGCCCACGCCGTACCCGCCAAGCAATGGAAGGTATCGATGCACTGCGTGAAGTTTGTGACACGCTTATCGTT
ATTCCAAACGATCGCCTACTTCAGCTTGGCGACGCCAACATCACCATGGTTGATGCGTTCCACGAAGCAGACCGCGTGCT
TCACAATGGTGTCCAAGGTATTACCGATCTCATTACCATTCCTGGTCTGATTAACGTTGACTTCGCCGACGTTCGTTCTG
TTATGCACGATGCTGGCTCCGCCTTGATGGGTGTTGGTTCTGCATCTGGTGAAAATCGAGTGCTTACTGCTGCTGAGCAG
GCAATTAACTCACCACTGTTGGAATCCACGATGGAAGGTGCCAAGGGAGTTTTGCTCTCCGTTGCAGGTGGCTCAGACTT
GGGGCTGCAAGAAGTCAACGAGGCCGCATCCATGGTCCAGGAAAAAGCAGATGAGGACGTTAACCTCATCTTCGGTACCA
TTTTCGACGACAACCTCGGAGACGAGGTTCGTATTACCGTGATCGCTACTGGTTTTGACGGTGAGAAGAATTCTCTCGAT
CGTCAACGCGAAGCTGCGCAGCCAGCTGCTTCACAATCAGCATCTGCAATGGAAGCCAATCCAACTCCTGCGCCTGATCG
CTCTACGTCGACGTCGTTGTTTGGGGATTCAGATAGTGCTCCGCGCCATCGCTTGAATGAGGAACCTGCTGCGCGACGGA
CTTCCCATGATTCTGAGGGAATGTACACGCGCCGGTCGGTGCCTCGTGAGTCCTATCGCGATCAGCGTTCTGATGACTTT
GATGACGATCTCGATATTCCAGACTTCCTACGCTAA

Upstream 100 bases:

>100_bases
TGAAGCAATGCTGCTCTCCATGGTGTCTGTGGGGTGTGGCGGGGCAATCGGTGCATCGCAAGTGAACGTTTTCCCACAAA
AGTGAAAGGCGAGTCTCTTA

Downstream 100 bases:

>100_bases
TGAGTACATCTGTGCACAACCGTCCTGTTCGTAAGGTTTTCACCAATCGATTAGGAGGGGTATCGCAACCGCCATATAGC
TCTTTTAACCTAGGCGATCA

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTSPDNYLAVIKVVGVGGGGVNAVNRMIEEGLKGVEFIAVNTDSQALMFSDADVKLDIGREATRGLGAGANPEVGRASAE
DHKNEIEETLKGADMVFVTAGEGGGTGTGAAPVVAGIAKRLGALTVGVVTRPFKFEGPRRTRQAMEGIDALREVCDTLIV
IPNDRLLQLGDANITMVDAFHEADRVLHNGVQGITDLITIPGLINVDFADVRSVMHDAGSALMGVGSASGENRVLTAAEQ
AINSPLLESTMEGAKGVLLSVAGGSDLGLQEVNEAASMVQEKADEDVNLIFGTIFDDNLGDEVRITVIATGFDGEKNSLD
RQREAAQPAASQSASAMEANPTPAPDRSTSTSLFGDSDSAPRHRLNEEPAARRTSHDSEGMYTRRSVPRESYRDQRSDDF
DDDLDIPDFLR

Sequences:

>Translated_411_residues
MTSPDNYLAVIKVVGVGGGGVNAVNRMIEEGLKGVEFIAVNTDSQALMFSDADVKLDIGREATRGLGAGANPEVGRASAE
DHKNEIEETLKGADMVFVTAGEGGGTGTGAAPVVAGIAKRLGALTVGVVTRPFKFEGPRRTRQAMEGIDALREVCDTLIV
IPNDRLLQLGDANITMVDAFHEADRVLHNGVQGITDLITIPGLINVDFADVRSVMHDAGSALMGVGSASGENRVLTAAEQ
AINSPLLESTMEGAKGVLLSVAGGSDLGLQEVNEAASMVQEKADEDVNLIFGTIFDDNLGDEVRITVIATGFDGEKNSLD
RQREAAQPAASQSASAMEANPTPAPDRSTSTSLFGDSDSAPRHRLNEEPAARRTSHDSEGMYTRRSVPRESYRDQRSDDF
DDDLDIPDFLR
>Mature_410_residues
TSPDNYLAVIKVVGVGGGGVNAVNRMIEEGLKGVEFIAVNTDSQALMFSDADVKLDIGREATRGLGAGANPEVGRASAED
HKNEIEETLKGADMVFVTAGEGGGTGTGAAPVVAGIAKRLGALTVGVVTRPFKFEGPRRTRQAMEGIDALREVCDTLIVI
PNDRLLQLGDANITMVDAFHEADRVLHNGVQGITDLITIPGLINVDFADVRSVMHDAGSALMGVGSASGENRVLTAAEQA
INSPLLESTMEGAKGVLLSVAGGSDLGLQEVNEAASMVQEKADEDVNLIFGTIFDDNLGDEVRITVIATGFDGEKNSLDR
QREAAQPAASQSASAMEANPTPAPDRSTSTSLFGDSDSAPRHRLNEEPAARRTSHDSEGMYTRRSVPRESYRDQRSDDFD
DDLDIPDFLR

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=311, Percent_Identity=50.4823151125402, Blast_Score=264, Evalue=7e-72,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 43467; Mature: 43336

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPDNYLAVIKVVGVGGGGVNAVNRMIEEGLKGVEFIAVNTDSQALMFSDADVKLDIGR
CCCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEEEECCC
EATRGLGAGANPEVGRASAEDHKNEIEETLKGADMVFVTAGEGGGTGTGAAPVVAGIAKR
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
LGALTVGVVTRPFKFEGPRRTRQAMEGIDALREVCDTLIVIPNDRLLQLGDANITMVDAF
HHHEEHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCEEEECCCCEEEEHHH
HEADRVLHNGVQGITDLITIPGLINVDFADVRSVMHDAGSALMGVGSASGENRVLTAAEQ
HHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCHHHEECCCCCCCCCEEHHHHH
AINSPLLESTMEGAKGVLLSVAGGSDLGLQEVNEAASMVQEKADEDVNLIFGTIFDDNLG
HHCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
DEVRITVIATGFDGEKNSLDRQREAAQPAASQSASAMEANPTPAPDRSTSTSLFGDSDSA
CEEEEEEEEECCCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PRHRLNEEPAARRTSHDSEGMYTRRSVPRESYRDQRSDDFDDDLDIPDFLR
CHHHCCCCCHHHHCCCCCCCCCHHHCCCHHHHHHCCCCCCCCCCCCHHHCC
>Mature Secondary Structure 
TSPDNYLAVIKVVGVGGGGVNAVNRMIEEGLKGVEFIAVNTDSQALMFSDADVKLDIGR
CCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEEEECCC
EATRGLGAGANPEVGRASAEDHKNEIEETLKGADMVFVTAGEGGGTGTGAAPVVAGIAKR
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
LGALTVGVVTRPFKFEGPRRTRQAMEGIDALREVCDTLIVIPNDRLLQLGDANITMVDAF
HHHEEHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCEEEECCCCEEEEHHH
HEADRVLHNGVQGITDLITIPGLINVDFADVRSVMHDAGSALMGVGSASGENRVLTAAEQ
HHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCHHHEECCCCCCCCCEEHHHHH
AINSPLLESTMEGAKGVLLSVAGGSDLGLQEVNEAASMVQEKADEDVNLIFGTIFDDNLG
HHCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
DEVRITVIATGFDGEKNSLDRQREAAQPAASQSASAMEANPTPAPDRSTSTSLFGDSDSA
CEEEEEEEEECCCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PRHRLNEEPAARRTSHDSEGMYTRRSVPRESYRDQRSDDFDDDLDIPDFLR
CHHHCCCCCHHHHCCCCCCCCCHHHCCCHHHHHHCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9240446; 9738885; 12948626 [H]