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The map label for this gene is lspA [H]

Identifier: 38234159

GI number: 38234159

Start: 1612368

End: 1612892

Strand: Reverse

Name: lspA [H]

Synonym: DIP1584

Alternate gene names: 38234159

Gene position: 1612892-1612368 (Counterclockwise)

Preceding gene: 38234161

Following gene: 38234158

Centisome position: 64.81

GC content: 48.76

Gene sequence:

>525_bases
GTGAGTCTAACGGACAGGAGTAATCCAGAGGCACGACGTCAAAAACAAAGCCAGACGTGGGTTGGTGTTATGGCAGCGAT
CATCGCGCTCGTGGCACTTGTTGATCAGCTGGTAAAAACGTGGATGCTTTCGGCATTGCGTGATGGGAACATCATCTACC
TCGTGGGGGATTGGTTCCGGTTGCGGTTGCTGTTTAATTCCGGAGCGGCGTTTTCAATTGGAGAAAACGCTACGTGGGTG
TTCACGTGTATCCAATTGATTTTTGTCATTGGAATCGTCGCTACGATGCGTAAAATCAAAGATCCATGGCAGGCTGTCGG
CCTCGCGTTGATTGCGGGGGGTGCGTTAGGCAACCTTATTGATCGGTTATTTCGAGCACCAGCATTTTTTATCGGCCACG
TTGTGGATTTTATTTCGGTAGGAAATTTTGCAGTTTTTAATGTCGCTGATAGTGCCATTAGCTGTGGTGTGGTTCTTGTT
GTGATCGCAATGCTGTTGGAAGGCCGTAAGGAGGGGAAGGAATGA

Upstream 100 bases:

>100_bases
TGCGGGAAATTGATCGTTTTTGTAGGCGCACCAGCGTCATTTTAGCGGGGTTAGCCTGTCGGTTGTTAGTTTGAGGTGGA
TTTTTGCCAAGATATAAGGC

Downstream 100 bases:

>100_bases
GCCGCGAACAAAGATCGTTGCCGGTCCCTGAGGGGCTAGCAGGCATGCGTGTCGACGCCGCCCTGAGCAAACTTTTAGGT
ATTTCTCGAACCGCAGCTGC

Product: putative lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSLTDRSNPEARRQKQSQTWVGVMAAIIALVALVDQLVKTWMLSALRDGNIIYLVGDWFRLRLLFNSGAAFSIGENATWV
FTCIQLIFVIGIVATMRKIKDPWQAVGLALIAGGALGNLIDRLFRAPAFFIGHVVDFISVGNFAVFNVADSAISCGVVLV
VIAMLLEGRKEGKE

Sequences:

>Translated_174_residues
MSLTDRSNPEARRQKQSQTWVGVMAAIIALVALVDQLVKTWMLSALRDGNIIYLVGDWFRLRLLFNSGAAFSIGENATWV
FTCIQLIFVIGIVATMRKIKDPWQAVGLALIAGGALGNLIDRLFRAPAFFIGHVVDFISVGNFAVFNVADSAISCGVVLV
VIAMLLEGRKEGKE
>Mature_173_residues
SLTDRSNPEARRQKQSQTWVGVMAAIIALVALVDQLVKTWMLSALRDGNIIYLVGDWFRLRLLFNSGAAFSIGENATWVF
TCIQLIFVIGIVATMRKIKDPWQAVGLALIAGGALGNLIDRLFRAPAFFIGHVVDFISVGNFAVFNVADSAISCGVVLVV
IAMLLEGRKEGKE

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18999; Mature: 18867

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00855 SPASE_II ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTDRSNPEARRQKQSQTWVGVMAAIIALVALVDQLVKTWMLSALRDGNIIYLVGDWFR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHH
LRLLFNSGAAFSIGENATWVFTCIQLIFVIGIVATMRKIKDPWQAVGLALIAGGALGNLI
HHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
DRLFRAPAFFIGHVVDFISVGNFAVFNVADSAISCGVVLVVIAMLLEGRKEGKE
HHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLTDRSNPEARRQKQSQTWVGVMAAIIALVALVDQLVKTWMLSALRDGNIIYLVGDWFR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHH
LRLLFNSGAAFSIGENATWVFTCIQLIFVIGIVATMRKIKDPWQAVGLALIAGGALGNLI
HHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
DRLFRAPAFFIGHVVDFISVGNFAVFNVADSAISCGVVLVVIAMLLEGRKEGKE
HHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA