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The map label for this gene is tsf

Identifier: 38234086

GI number: 38234086

Start: 1530890

End: 1531717

Strand: Reverse

Name: tsf

Synonym: DIP1507

Alternate gene names: 38234086

Gene position: 1531717-1530890 (Counterclockwise)

Preceding gene: 38234087

Following gene: 38234085

Centisome position: 61.55

GC content: 55.19

Gene sequence:

>828_bases
ATGGCGAACTACACTGCTGCTGACGTTAAGAAGCTGCGTGAAATCACCGGCTCCGGCATGCTCGACTGCAAGAAGGCTCT
GGAAGAGACCAACGGTGACTTCGACAAGGCCGTTGAGGTTCTTCGCATCAAGGGTGCAAAGGACGTCGGAAAGCGCGCTG
AGCGCAACGCAACCGAGGGCCTGATTGCTGTTTCTGGCAACACCATGGTTGAGATCAACTCCGAGACGGACTTCGTTGCA
AAGAACGCAGAGTTCAAGGAATTTGCTCAGAAGGTTGCTGACGCAGCTGCAGCTGTTAAGGCAAACACCCCTGAGGAACT
CGCTGCTGCTGATCTTGATGGCAAGACCGCTGCTGATGCAATTCAGGAATTGTCCGCAAAGATCGGTGAGAAGCTCGAGC
TGCGTCGTGCTATCACCTTGGAAGGCGAGAAGCTCTCCGTTTACCTCCACCAGCGTTCCGCTGACCTGCCTCCAGCAGTG
GGCGTTTTGGTTGCCTACACCGGTGAAGGTGAAGCAGCTCAGGCTGCCGCTCACGCCGCTGCAATGCAGGTTGCTGCTCT
CAAGGCTCAGTACCTGACCCGTGAGGATGTTCCTGCTGAGGTCATCGAGAAGGAGCGCTCCATCGCTGAGCAGATCACCC
GTGAAGAGGGCAAGCCAGAAAAGGCAATTCCGAAGATCGTTGAGGGTCGTCTGAACGGCTTCTACAAGGATGTGTGCTTG
GTTGAGCAGGCTTCCGTTGCAGATAGCAAGAAGACTGTTAAGCAGGTCATGGATGAAGCTGGTGTTACCTTGACCGGTTT
CGCTCGCTATGAGGTTGGCCAGCACTAA

Upstream 100 bases:

>100_bases
GCATACTCAATAAAGAGCTGCATTATTGGCACGTGTTAGCTACGCTCGTCTACGAGAAAACTTTTTACATTTTTCCAATA
CAAGGAGGGTCGCCCACAAC

Downstream 100 bases:

>100_bases
TTACAGTGTGGTAGCTTTTAGCTAGTAATAATGCCCGTGCATTCGTGCACGGGCATTATTGTGTTATTTGGTGTTCCTTG
TTAGTTGGTCGGGGTGTGAA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MANYTAADVKKLREITGSGMLDCKKALEETNGDFDKAVEVLRIKGAKDVGKRAERNATEGLIAVSGNTMVEINSETDFVA
KNAEFKEFAQKVADAAAAVKANTPEELAAADLDGKTAADAIQELSAKIGEKLELRRAITLEGEKLSVYLHQRSADLPPAV
GVLVAYTGEGEAAQAAAHAAAMQVAALKAQYLTREDVPAEVIEKERSIAEQITREEGKPEKAIPKIVEGRLNGFYKDVCL
VEQASVADSKKTVKQVMDEAGVTLTGFARYEVGQH

Sequences:

>Translated_275_residues
MANYTAADVKKLREITGSGMLDCKKALEETNGDFDKAVEVLRIKGAKDVGKRAERNATEGLIAVSGNTMVEINSETDFVA
KNAEFKEFAQKVADAAAAVKANTPEELAAADLDGKTAADAIQELSAKIGEKLELRRAITLEGEKLSVYLHQRSADLPPAV
GVLVAYTGEGEAAQAAAHAAAMQVAALKAQYLTREDVPAEVIEKERSIAEQITREEGKPEKAIPKIVEGRLNGFYKDVCL
VEQASVADSKKTVKQVMDEAGVTLTGFARYEVGQH
>Mature_274_residues
ANYTAADVKKLREITGSGMLDCKKALEETNGDFDKAVEVLRIKGAKDVGKRAERNATEGLIAVSGNTMVEINSETDFVAK
NAEFKEFAQKVADAAAAVKANTPEELAAADLDGKTAADAIQELSAKIGEKLELRRAITLEGEKLSVYLHQRSADLPPAVG
VLVAYTGEGEAAQAAAHAAAMQVAALKAQYLTREDVPAEVIEKERSIAEQITREEGKPEKAIPKIVEGRLNGFYKDVCLV
EQASVADSKKTVKQVMDEAGVTLTGFARYEVGQH

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Escherichia coli, GI1786366, Length=278, Percent_Identity=43.5251798561151, Blast_Score=183, Evalue=1e-47,
Organism=Drosophila melanogaster, GI19921466, Length=292, Percent_Identity=30.1369863013699, Blast_Score=84, Evalue=8e-17,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_CORDI (P61332)

Other databases:

- EMBL:   BX248358
- RefSeq:   NP_939853.1
- ProteinModelPortal:   P61332
- SMR:   P61332
- GeneID:   2650391
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1507
- NMPDR:   fig|257309.1.peg.1444
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- BioCyc:   CDIP257309:DIP1507-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 29464; Mature: 29332

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYTAADVKKLREITGSGMLDCKKALEETNGDFDKAVEVLRIKGAKDVGKRAERNATEG
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCC
LIAVSGNTMVEINSETDFVAKNAEFKEFAQKVADAAAAVKANTPEELAAADLDGKTAADA
EEEECCCEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHH
IQELSAKIGEKLELRRAITLEGEKLSVYLHQRSADLPPAVGVLVAYTGEGEAAQAAAHAA
HHHHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHH
AMQVAALKAQYLTREDVPAEVIEKERSIAEQITREEGKPEKAIPKIVEGRLNGFYKDVCL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VEQASVADSKKTVKQVMDEAGVTLTGFARYEVGQH
HHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCCC
>Mature Secondary Structure 
ANYTAADVKKLREITGSGMLDCKKALEETNGDFDKAVEVLRIKGAKDVGKRAERNATEG
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCC
LIAVSGNTMVEINSETDFVAKNAEFKEFAQKVADAAAAVKANTPEELAAADLDGKTAADA
EEEECCCEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHH
IQELSAKIGEKLELRRAITLEGEKLSVYLHQRSADLPPAVGVLVAYTGEGEAAQAAAHAA
HHHHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHH
AMQVAALKAQYLTREDVPAEVIEKERSIAEQITREEGKPEKAIPKIVEGRLNGFYKDVCL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VEQASVADSKKTVKQVMDEAGVTLTGFARYEVGQH
HHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910