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The map label for this gene is lacC2 [H]

Identifier: 38234015

GI number: 38234015

Start: 1451300

End: 1452265

Strand: Direct

Name: lacC2 [H]

Synonym: DIP1430

Alternate gene names: 38234015

Gene position: 1451300-1452265 (Clockwise)

Preceding gene: 38234014

Following gene: 38234016

Centisome position: 58.32

GC content: 50.93

Gene sequence:

>966_bases
GTGATTCTGACGTTTACCCCAAATCCCAGCATCGATAAGACCCTCCAGTTGGATTCCGTACTTACTCGAGGCGCAGTACA
ACGCTTATCAGGCGTACAAACAGTTGCAGGAGGAAAGGGGATAAATGTTGCCGTTGCTTTAGCAAAGGCGCAGGCCGACA
CCGTAGCGCTTTACCCAGCCCACCCAGAAGATCCATTTAATAAGCTGATCCGAGAGTCCCAAATTCCAGCGCAAAGAGTG
ACAATCCGCGGTGAAGTGCGAATAAACACGACAGTGACTGAACCTGACGGCACAACCACAAAGCTCAATATTCAAGGCCC
GCAAATTCACGAGGACGAGTTACAAGCCTTGCAGAAAAACCTCCTAGAACGCACGGCACGTTGTTCATGGGCAGTTCTCG
CAGGTTCCTTGCCTCCAGGAGTTCCTACTGACTGGTATGTACATCTGACAAAATTGCTCAACGCTCGCCATCCCTCGCTG
CGAATTGCTATTGACACTTCCGACGTACCATTGCAAAAAGTTGGGGAATCATTCGGCAACTGTGCACTGTCGCTAATAAA
ACCCAATGGTATGGAACTTGGTCAACTTGTTGGGCTTGATGGCTACGTTTTGGAAAAAGAAGCAGCGCAAGGAAACTTCG
ACCCCGTTGTCAGCGCAGCCCGTAAAGCAATCCTCCAAGGTGTTGAAAATGTGCTCGTAACTCTAGGCGCTGCTGGCGCC
GTATTAGTTACTAAAGATCATGCGTGGAAAGCTACGCCCCCACCCATTACTGTCCTTTCTACAGTGGGAGCTGGGGACGC
CTCCTTAGCCGGTTTTATTCTTGCGTCGGAAGATGGGCTGCCTCCGGAAAAATGCCTAGCTCAGGCTGTCGCTTACGGCG
CAGCCGCTGCTAGTTTTGCAGGCACTCACATGCCATATCCTCATCAAATCGACGTCAATCACACACCTGTCACTCTCCTT
TCCTAG

Upstream 100 bases:

>100_bases
TTGCGCAGCTTGCCGATGTTGACTTTGTTGTTACTGATCGCAACTCTCCTCCTCAGCTTTCCCGCCAGCTCGGCGAACCC
AATTTACAAGTGGTGATCCC

Downstream 100 bases:

>100_bases
CCCACCCCGCTTTCCACCCAGTGGAAACTATTATTGCTACACTCATGTGTCTTTATATTTCATCTTGGTAACTAACTAAA
CCTACGCGTTCAAGGACACA

Product: putative phosphofructokinase (PTS system)

Products: NA

Alternate protein names: Phosphotagatokinase 2 [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MILTFTPNPSIDKTLQLDSVLTRGAVQRLSGVQTVAGGKGINVAVALAKAQADTVALYPAHPEDPFNKLIRESQIPAQRV
TIRGEVRINTTVTEPDGTTTKLNIQGPQIHEDELQALQKNLLERTARCSWAVLAGSLPPGVPTDWYVHLTKLLNARHPSL
RIAIDTSDVPLQKVGESFGNCALSLIKPNGMELGQLVGLDGYVLEKEAAQGNFDPVVSAARKAILQGVENVLVTLGAAGA
VLVTKDHAWKATPPPITVLSTVGAGDASLAGFILASEDGLPPEKCLAQAVAYGAAAASFAGTHMPYPHQIDVNHTPVTLL
S

Sequences:

>Translated_321_residues
MILTFTPNPSIDKTLQLDSVLTRGAVQRLSGVQTVAGGKGINVAVALAKAQADTVALYPAHPEDPFNKLIRESQIPAQRV
TIRGEVRINTTVTEPDGTTTKLNIQGPQIHEDELQALQKNLLERTARCSWAVLAGSLPPGVPTDWYVHLTKLLNARHPSL
RIAIDTSDVPLQKVGESFGNCALSLIKPNGMELGQLVGLDGYVLEKEAAQGNFDPVVSAARKAILQGVENVLVTLGAAGA
VLVTKDHAWKATPPPITVLSTVGAGDASLAGFILASEDGLPPEKCLAQAVAYGAAAASFAGTHMPYPHQIDVNHTPVTLL
S
>Mature_321_residues
MILTFTPNPSIDKTLQLDSVLTRGAVQRLSGVQTVAGGKGINVAVALAKAQADTVALYPAHPEDPFNKLIRESQIPAQRV
TIRGEVRINTTVTEPDGTTTKLNIQGPQIHEDELQALQKNLLERTARCSWAVLAGSLPPGVPTDWYVHLTKLLNARHPSL
RIAIDTSDVPLQKVGESFGNCALSLIKPNGMELGQLVGLDGYVLEKEAAQGNFDPVVSAARKAILQGVENVLVTLGAAGA
VLVTKDHAWKATPPPITVLSTVGAGDASLAGFILASEDGLPPEKCLAQAVAYGAAAASFAGTHMPYPHQIDVNHTPVTLL
S

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family. LacC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=274, Percent_Identity=29.5620437956204, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1788017, Length=308, Percent_Identity=30.5194805194805, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR005926
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.144 [H]

Molecular weight: Translated: 33824; Mature: 33824

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTFTPNPSIDKTLQLDSVLTRGAVQRLSGVQTVAGGKGINVAVALAKAQADTVALYPA
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEEEECCCCEEEEECC
HPEDPFNKLIRESQIPAQRVTIRGEVRINTTVTEPDGTTTKLNIQGPQIHEDELQALQKN
CCCCHHHHHHHHHCCCHHHEEEEEEEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHH
LLERTARCSWAVLAGSLPPGVPTDWYVHLTKLLNARHPSLRIAIDTSDVPLQKVGESFGN
HHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCC
CALSLIKPNGMELGQLVGLDGYVLEKEAAQGNFDPVVSAARKAILQGVENVLVTLGAAGA
EEEEEECCCCCCHHHEECCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
VLVTKDHAWKATPPPITVLSTVGAGDASLAGFILASEDGLPPEKCLAQAVAYGAAAASFA
EEEEECCCCCCCCCCEEEEEECCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
GTHMPYPHQIDVNHTPVTLLS
CCCCCCCCEEECCCCCEEEEC
>Mature Secondary Structure
MILTFTPNPSIDKTLQLDSVLTRGAVQRLSGVQTVAGGKGINVAVALAKAQADTVALYPA
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEEEECCCCEEEEECC
HPEDPFNKLIRESQIPAQRVTIRGEVRINTTVTEPDGTTTKLNIQGPQIHEDELQALQKN
CCCCHHHHHHHHHCCCHHHEEEEEEEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHH
LLERTARCSWAVLAGSLPPGVPTDWYVHLTKLLNARHPSLRIAIDTSDVPLQKVGESFGN
HHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCC
CALSLIKPNGMELGQLVGLDGYVLEKEAAQGNFDPVVSAARKAILQGVENVLVTLGAAGA
EEEEEECCCCCCHHHEECCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
VLVTKDHAWKATPPPITVLSTVGAGDASLAGFILASEDGLPPEKCLAQAVAYGAAAASFA
EEEEECCCCCCCCCCEEEEEECCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
GTHMPYPHQIDVNHTPVTLLS
CCCCCCCCEEECCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12354221 [H]