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The map label for this gene is oxyR [H]

Identifier: 38234006

GI number: 38234006

Start: 1439301

End: 1440239

Strand: Direct

Name: oxyR [H]

Synonym: DIP1421

Alternate gene names: 38234006

Gene position: 1439301-1440239 (Clockwise)

Preceding gene: 38234003

Following gene: 38234008

Centisome position: 57.83

GC content: 51.65

Gene sequence:

>939_bases
ATGAGCAATAAAGAATATCGGCCAACCCTTGCACAGCTGCGCACGTTCGCCACCATTGCGGAAAACAAGCATTTTGGGAC
CGCAGCTGCCAAGCTTTCGATTTCTCAACCATCGCTTTCGCAAGCGTTAGCAGCTCTTGAAAACGGCCTTGGTGTTCAGC
TCATTGAACGCTCCACACGGCGAGTCATCGTCACTCCCGCTGGGGAAATGCTCTTACCGTATGCAAAGGCCACGCTTGAT
GCGGCTGATGCTTTCCTTGCCCATGCACATGGTGCTTCCGGCACGCTTTCTGGCCCCATGAGTCTTGGTATCATTCCGAC
CATTGCCCCATATATCCTCCCGAATCTACTCGATGCTGTACGCGACGAGTTTCCCGACTTGGAGCTTCGAATCGTAGAAG
AGCAGACAAAGCACCTCATAGCGCTTCTTCGCGACGGACATATCGATTGTGCAATATTGGCGCTTCCGACTGAACAAATC
GGTTTTACAGAAATGCCACTTTATGTCGAAGATTTCCGCATGGTGACAACAGAAGATCACCCATTGGCGCATCGCAATGA
CTTAACTCTTTCTCATCTCAAAGAGCTTGATCTTTTGCTTCTCGACGACGGCCACTGCCTTCGCGACCAGATCGTAGATC
TATGCCGACACGTTGACGTAAATCCCACACACAGCAAGGCGGCAGAGACCCGCGCGGCCAGCTTGACTACTGTTATGCAA
TTGGTCAGTGCTGGAATGGGCGCTACCTTAGTGCCGGAAAGCTCAGTGTCCATAGAATGCTCGCGCCCAGGCTTGGCCAC
GGCTACTTTCGCTCCTGAAGTTAGTGCTTCGCGTCAAGTGGGAATGGTGTACCGAACATCATCCTCAAGGACTGAGGAGT
TTCAAAAGCTAGGTTCTATAGTTGGCCAAGCGTTTCAAGACGTTATCGCGCAGAATTAG

Upstream 100 bases:

>100_bases
GAATATGGGACTAAGGTTTTGGCTCCTGTCATTGTTTATACCTATACAGCGAACACCTGTCAATATGACTTTCTTTTAAA
AGTGTCTATAATAAATAGGC

Downstream 100 bases:

>100_bases
CATAATAAAAATGGTGGAGAGGATTTCACGATCCTCACCACCATTCTCTTATTTCCTATGCTTTCAACGGAACCGTTCCT
TGAGCAATTTGCCGATACAT

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSNKEYRPTLAQLRTFATIAENKHFGTAAAKLSISQPSLSQALAALENGLGVQLIERSTRRVIVTPAGEMLLPYAKATLD
AADAFLAHAHGASGTLSGPMSLGIIPTIAPYILPNLLDAVRDEFPDLELRIVEEQTKHLIALLRDGHIDCAILALPTEQI
GFTEMPLYVEDFRMVTTEDHPLAHRNDLTLSHLKELDLLLLDDGHCLRDQIVDLCRHVDVNPTHSKAAETRAASLTTVMQ
LVSAGMGATLVPESSVSIECSRPGLATATFAPEVSASRQVGMVYRTSSSRTEEFQKLGSIVGQAFQDVIAQN

Sequences:

>Translated_312_residues
MSNKEYRPTLAQLRTFATIAENKHFGTAAAKLSISQPSLSQALAALENGLGVQLIERSTRRVIVTPAGEMLLPYAKATLD
AADAFLAHAHGASGTLSGPMSLGIIPTIAPYILPNLLDAVRDEFPDLELRIVEEQTKHLIALLRDGHIDCAILALPTEQI
GFTEMPLYVEDFRMVTTEDHPLAHRNDLTLSHLKELDLLLLDDGHCLRDQIVDLCRHVDVNPTHSKAAETRAASLTTVMQ
LVSAGMGATLVPESSVSIECSRPGLATATFAPEVSASRQVGMVYRTSSSRTEEFQKLGSIVGQAFQDVIAQN
>Mature_311_residues
SNKEYRPTLAQLRTFATIAENKHFGTAAAKLSISQPSLSQALAALENGLGVQLIERSTRRVIVTPAGEMLLPYAKATLDA
ADAFLAHAHGASGTLSGPMSLGIIPTIAPYILPNLLDAVRDEFPDLELRIVEEQTKHLIALLRDGHIDCAILALPTEQIG
FTEMPLYVEDFRMVTTEDHPLAHRNDLTLSHLKELDLLLLDDGHCLRDQIVDLCRHVDVNPTHSKAAETRAASLTTVMQL
VSAGMGATLVPESSVSIECSRPGLATATFAPEVSASRQVGMVYRTSSSRTEEFQKLGSIVGQAFQDVIAQN

Specific function: Required for the induction the katG gene for catalase. Involved in the response to hydrogen peroxide [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=290, Percent_Identity=37.2413793103448, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1787879, Length=261, Percent_Identity=32.5670498084291, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI157672245, Length=280, Percent_Identity=27.8571428571429, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI2367136, Length=261, Percent_Identity=29.5019157088123, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI145693105, Length=249, Percent_Identity=28.9156626506024, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=28.8065843621399, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788297, Length=253, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87081904, Length=205, Percent_Identity=29.7560975609756, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788748, Length=294, Percent_Identity=24.8299319727891, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787530, Length=208, Percent_Identity=27.8846153846154, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787601, Length=147, Percent_Identity=29.2517006802721, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788481, Length=208, Percent_Identity=27.8846153846154, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789506, Length=176, Percent_Identity=24.4318181818182, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788296, Length=198, Percent_Identity=25.7575757575758, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790208, Length=246, Percent_Identity=26.0162601626016, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI48994962, Length=169, Percent_Identity=27.810650887574, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788626, Length=240, Percent_Identity=27.0833333333333, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1787806, Length=257, Percent_Identity=24.5136186770428, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33772; Mature: 33641

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKEYRPTLAQLRTFATIAENKHFGTAAAKLSISQPSLSQALAALENGLGVQLIERSTR
CCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEECCCC
RVIVTPAGEMLLPYAKATLDAADAFLAHAHGASGTLSGPMSLGIIPTIAPYILPNLLDAV
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RDEFPDLELRIVEEQTKHLIALLRDGHIDCAILALPTEQIGFTEMPLYVEDFRMVTTEDH
HHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEECHHHCCCCCCCEEEECEEEEECCCC
PLAHRNDLTLSHLKELDLLLLDDGHCLRDQIVDLCRHVDVNPTHSKAAETRAASLTTVMQ
CCCCCCCCCHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LVSAGMGATLVPESSVSIECSRPGLATATFAPEVSASRQVGMVYRTSSSRTEEFQKLGSI
HHHCCCCCEECCCCCCEEEECCCCCEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
VGQAFQDVIAQN
HHHHHHHHHCCC
>Mature Secondary Structure 
SNKEYRPTLAQLRTFATIAENKHFGTAAAKLSISQPSLSQALAALENGLGVQLIERSTR
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEECCCC
RVIVTPAGEMLLPYAKATLDAADAFLAHAHGASGTLSGPMSLGIIPTIAPYILPNLLDAV
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RDEFPDLELRIVEEQTKHLIALLRDGHIDCAILALPTEQIGFTEMPLYVEDFRMVTTEDH
HHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEECHHHCCCCCCCEEEECEEEEECCCC
PLAHRNDLTLSHLKELDLLLLDDGHCLRDQIVDLCRHVDVNPTHSKAAETRAASLTTVMQ
CCCCCCCCCHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LVSAGMGATLVPESSVSIECSRPGLATATFAPEVSASRQVGMVYRTSSSRTEEFQKLGSI
HHHCCCCCEECCCCCCEEEECCCCCEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
VGQAFQDVIAQN
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9733688 [H]