Click here to switch to the map view.

The map label for this gene is suhB [H]

Identifier: 38233988

GI number: 38233988

Start: 1420829

End: 1421662

Strand: Reverse

Name: suhB [H]

Synonym: DIP1403

Alternate gene names: 38233988

Gene position: 1421662-1420829 (Counterclockwise)

Preceding gene: 38233992

Following gene: 38233987

Centisome position: 57.13

GC content: 47.48

Gene sequence:

>834_bases
GTGGATTCTTTACGTGAGTATGCAGAATTGGCAGCGATAGCGGCAGAAGTGGCGTGTCAGGCATCAGATCACATTAGGCG
CACAATGAGAGAGCTTGGCGACGTTACCGCCGGAATGGAAACGAAATCATCTGATGTAGATCCCGTCACGATCGTTGATA
AGGCTGCTGAGCATTTTATCGCTGATGCATTGTCACACTTGCGACCAGGTGATGGGTTGTTAGGGGAAGAAGGAGCAGAA
TCTTCAAGCAGCACTGGAATAACATGGATAGTTGATCCTATTGATGGGACCGTGAATTTTATCTATGGAATTCCGCAATA
CGCGGTTTCGGTTGCGGCGTGTATAGGCGAGAACGTCGTGGCAGGCGCTGTGATTAATGTTGCAATTAGCGATCTTTATG
TTGCGGCATGTGGTAGCGGAGCTTTCGTTTTGAGGAGTGATTCTGATGCGCTCAAATCCATTGAGGCTTCAAAGTGTTCA
GATCTACAACACGCCTTGATCGCTACCGGATTTTCGTACTCTTCTCCGCGTCGAGAAGATCAAGCTAAGTTACTGGTTAG
TCTTTTGCCCAACGTGAGAGACATACGCAGATTTGGTAGTGCTGCTTTGGATCTTTGCGCTGTGGCTGAAGGGTGTTTTG
ATGGATACTACGAACACGGCCTTAATGCTTGGGATTTTGCTGCGGGTGCGTTAATCGCTCAAGAAGCGGGTGCCAAAATA
AAGCAGCCAGAGCTTAAATTGGCTTCTTCGGCGGGGGCACTACTTTTGGCTAGTTCATCGCCAATATTTCGTGAACTTGA
ACTGCAATTTTATCCATTTGACATGCGGAAATAA

Upstream 100 bases:

>100_bases
CCAACCGTGGATTCAAATTCCAATTTGCGAAATTTTCGGGGAGTAACACATGGCTAAAACAGGCTTGAAAGAACACATAG
TGGAGCAACTCTCTGTAAGA

Downstream 100 bases:

>100_bases
AAGGTTCTGCGAACGATTGCGTTTGTGGCTTTGCTACCCCCACTGGCGACACATGGATCGTGGAGGTGACAATCCCCAAA
AACTCACTTAATATGCGCCT

Product: putative hydrolase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MDSLREYAELAAIAAEVACQASDHIRRTMRELGDVTAGMETKSSDVDPVTIVDKAAEHFIADALSHLRPGDGLLGEEGAE
SSSSTGITWIVDPIDGTVNFIYGIPQYAVSVAACIGENVVAGAVINVAISDLYVAACGSGAFVLRSDSDALKSIEASKCS
DLQHALIATGFSYSSPRREDQAKLLVSLLPNVRDIRRFGSAALDLCAVAEGCFDGYYEHGLNAWDFAAGALIAQEAGAKI
KQPELKLASSAGALLLASSSPIFRELELQFYPFDMRK

Sequences:

>Translated_277_residues
MDSLREYAELAAIAAEVACQASDHIRRTMRELGDVTAGMETKSSDVDPVTIVDKAAEHFIADALSHLRPGDGLLGEEGAE
SSSSTGITWIVDPIDGTVNFIYGIPQYAVSVAACIGENVVAGAVINVAISDLYVAACGSGAFVLRSDSDALKSIEASKCS
DLQHALIATGFSYSSPRREDQAKLLVSLLPNVRDIRRFGSAALDLCAVAEGCFDGYYEHGLNAWDFAAGALIAQEAGAKI
KQPELKLASSAGALLLASSSPIFRELELQFYPFDMRK
>Mature_277_residues
MDSLREYAELAAIAAEVACQASDHIRRTMRELGDVTAGMETKSSDVDPVTIVDKAAEHFIADALSHLRPGDGLLGEEGAE
SSSSTGITWIVDPIDGTVNFIYGIPQYAVSVAACIGENVVAGAVINVAISDLYVAACGSGAFVLRSDSDALKSIEASKCS
DLQHALIATGFSYSSPRREDQAKLLVSLLPNVRDIRRFGSAALDLCAVAEGCFDGYYEHGLNAWDFAAGALIAQEAGAKI
KQPELKLASSAGALLLASSSPIFRELELQFYPFDMRK

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=237, Percent_Identity=32.0675105485232, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI221625487, Length=237, Percent_Identity=32.0675105485232, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI7657236, Length=241, Percent_Identity=32.3651452282158, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI221625507, Length=137, Percent_Identity=34.3065693430657, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1788882, Length=231, Percent_Identity=36.3636363636364, Blast_Score=120, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI193202570, Length=214, Percent_Identity=36.4485981308411, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI193202572, Length=217, Percent_Identity=34.1013824884793, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320493, Length=212, Percent_Identity=36.3207547169811, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321836, Length=212, Percent_Identity=29.2452830188679, Blast_Score=93, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24664922, Length=208, Percent_Identity=35.5769230769231, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24664926, Length=208, Percent_Identity=35.0961538461538, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357329, Length=265, Percent_Identity=31.3207547169811, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21357303, Length=212, Percent_Identity=33.4905660377358, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24664918, Length=203, Percent_Identity=32.0197044334975, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357957, Length=205, Percent_Identity=31.219512195122, Blast_Score=97, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29368; Mature: 29368

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLREYAELAAIAAEVACQASDHIRRTMRELGDVTAGMETKSSDVDPVTIVDKAAEHFI
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
ADALSHLRPGDGLLGEEGAESSSSTGITWIVDPIDGTVNFIYGIPQYAVSVAACIGENVV
HHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHCCCHH
AGAVINVAISDLYVAACGSGAFVLRSDSDALKSIEASKCSDLQHALIATGFSYSSPRRED
HHHHHHHHHHHHHHEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
QAKLLVSLLPNVRDIRRFGSAALDLCAVAEGCFDGYYEHGLNAWDFAAGALIAQEAGAKI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
KQPELKLASSAGALLLASSSPIFRELELQFYPFDMRK
CCCHHHHHCCCCEEEEECCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MDSLREYAELAAIAAEVACQASDHIRRTMRELGDVTAGMETKSSDVDPVTIVDKAAEHFI
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
ADALSHLRPGDGLLGEEGAESSSSTGITWIVDPIDGTVNFIYGIPQYAVSVAACIGENVV
HHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHCCCHH
AGAVINVAISDLYVAACGSGAFVLRSDSDALKSIEASKCSDLQHALIATGFSYSSPRRED
HHHHHHHHHHHHHHEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
QAKLLVSLLPNVRDIRRFGSAALDLCAVAEGCFDGYYEHGLNAWDFAAGALIAQEAGAKI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
KQPELKLASSAGALLLASSSPIFRELELQFYPFDMRK
CCCHHHHHCCCCEEEEECCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]