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The map label for this gene is rnd [H]

Identifier: 38233981

GI number: 38233981

Start: 1413434

End: 1414657

Strand: Direct

Name: rnd [H]

Synonym: DIP1396

Alternate gene names: 38233981

Gene position: 1413434-1414657 (Clockwise)

Preceding gene: 38233980

Following gene: 38233986

Centisome position: 56.8

GC content: 48.45

Gene sequence:

>1224_bases
ATGGCACTTTTAGTCACTCAACCGAGTGAGGGATTACCCCCGCTCGCTGCAACTTCTCGATCGATTTACGAGGCAGCTTA
TCAACTATCTCAGGGCACTGGCCCTTTCGCAATTGATACTGAACGCGCTGGAGCTTATCGTTATGATGATCGCGCTTATC
TCTTACAGATTCGTCGCGAAGGAAGCGGCACAGTACTTATCGACCCAGAAGCGAATCGACGATTAGTCACATCTGTACTA
GGCAAGGTAATAAACAATCAACCGTGGATTATCCATGCCGCGGCAACAGACCTCCCCTGTCTTTCCGAGTTAGGTTTCTA
CCCCAGTACAATTTTCGATACTGAATTAGCAGGAAGACTCGCTGGATTGCCGCGAGTTAATTTAGCGTCCATGCTCGAAG
AGCGCTTGGAAGTTACCCTCAAAAAGGCACACGGTGCCGAAGACTGGTCACGTCGCCCGCTTCCCCACAGTTGGCTCGTT
TATGCAGCCTTAGACGTCGAGAAGCTCATTCCACTTGCAGAATCCATGAAACTCCTCCTAGAGGCTCATGGAAAATTAGA
ATGGCACAAACAAGAATGTGCGCATCTCATAAATACAAGCAGTCATGGCTTAGACACACAGCGTAGCTGGCAAGATATAA
AGGGGGTAAGCCGTCTTACCCGACCTCGGCAGCTAGTCGTTGCCGAAGCCCTCTGGGAGTTACGCGACGATGAAGCTCGT
ATGAAAAATACATCCGTATCTCGCTTGTTGCCGGACAAAGTACTGATTTCCGTTGCACAGCGTCCACCTCGCAATTCACA
AGCTGCTCTACGCGCCTCAGAGATTCCTAAACAGTACCGTAAGCGGATCGCTCGTTGGATGCCGACGATCAACGATGTTT
TGGAATCCGATCCACGCACTTGGCCACACACACCACAATTCGATGAGAACCAGTTGCCATCAAAGTACGTTTGGGAAAAG
ATCCATCCCGAATCTTTAGATGACTTTGAAGAGGTAAAAAATTCCATCGTTGAAAAGGCGCTACTTCTAAATCTTCCAGC
AGAAAATCTCATGCAGCCCCACTCGGTTAAAGAATTATGCTGGCAACTTCGAGATGTACCACGACCGATCGCACAAGACG
ATGTAATTGAATGCCTCATGAGATTAGAGGCACGACCTTGGCAAATCGACAACAGTGCGTCAGTAATTACAGATACACTC
AACAAAATTGAGCACGCCTCATAG

Upstream 100 bases:

>100_bases
ACCTCATGTATCAGCTTTTGCTCAAGTGTTAGCAAATGTAGCCGGACTGTCTCCCGAAGGTACGACAAGTATCTCCCGAT
AACCTAAACTTTTTACTGCT

Downstream 100 bases:

>100_bases
AGAAATACAGGGACGAGCCTAGATTCCAAAAAATCAAGGCCCGTCCCTCGCTTACAGAAGCTATTCCTTGTCTAAAAGGT
AAAGAGATTCTGCAGCTGCG

Product: putative ribonuclease

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MALLVTQPSEGLPPLAATSRSIYEAAYQLSQGTGPFAIDTERAGAYRYDDRAYLLQIRREGSGTVLIDPEANRRLVTSVL
GKVINNQPWIIHAAATDLPCLSELGFYPSTIFDTELAGRLAGLPRVNLASMLEERLEVTLKKAHGAEDWSRRPLPHSWLV
YAALDVEKLIPLAESMKLLLEAHGKLEWHKQECAHLINTSSHGLDTQRSWQDIKGVSRLTRPRQLVVAEALWELRDDEAR
MKNTSVSRLLPDKVLISVAQRPPRNSQAALRASEIPKQYRKRIARWMPTINDVLESDPRTWPHTPQFDENQLPSKYVWEK
IHPESLDDFEEVKNSIVEKALLLNLPAENLMQPHSVKELCWQLRDVPRPIAQDDVIECLMRLEARPWQIDNSASVITDTL
NKIEHAS

Sequences:

>Translated_407_residues
MALLVTQPSEGLPPLAATSRSIYEAAYQLSQGTGPFAIDTERAGAYRYDDRAYLLQIRREGSGTVLIDPEANRRLVTSVL
GKVINNQPWIIHAAATDLPCLSELGFYPSTIFDTELAGRLAGLPRVNLASMLEERLEVTLKKAHGAEDWSRRPLPHSWLV
YAALDVEKLIPLAESMKLLLEAHGKLEWHKQECAHLINTSSHGLDTQRSWQDIKGVSRLTRPRQLVVAEALWELRDDEAR
MKNTSVSRLLPDKVLISVAQRPPRNSQAALRASEIPKQYRKRIARWMPTINDVLESDPRTWPHTPQFDENQLPSKYVWEK
IHPESLDDFEEVKNSIVEKALLLNLPAENLMQPHSVKELCWQLRDVPRPIAQDDVIECLMRLEARPWQIDNSASVITDTL
NKIEHAS
>Mature_406_residues
ALLVTQPSEGLPPLAATSRSIYEAAYQLSQGTGPFAIDTERAGAYRYDDRAYLLQIRREGSGTVLIDPEANRRLVTSVLG
KVINNQPWIIHAAATDLPCLSELGFYPSTIFDTELAGRLAGLPRVNLASMLEERLEVTLKKAHGAEDWSRRPLPHSWLVY
AALDVEKLIPLAESMKLLLEAHGKLEWHKQECAHLINTSSHGLDTQRSWQDIKGVSRLTRPRQLVVAEALWELRDDEARM
KNTSVSRLLPDKVLISVAQRPPRNSQAALRASEIPKQYRKRIARWMPTINDVLESDPRTWPHTPQFDENQLPSKYVWEKI
HPESLDDFEEVKNSIVEKALLLNLPAENLMQPHSVKELCWQLRDVPRPIAQDDVIECLMRLEARPWQIDNSASVITDTLN
KIEHAS

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=233, Percent_Identity=30.9012875536481, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI161078302, Length=268, Percent_Identity=25.7462686567164, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 46190; Mature: 46059

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLVTQPSEGLPPLAATSRSIYEAAYQLSQGTGPFAIDTERAGAYRYDDRAYLLQIRRE
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCEEEEEEEEC
GSGTVLIDPEANRRLVTSVLGKVINNQPWIIHAAATDLPCLSELGFYPSTIFDTELAGRL
CCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHH
AGLPRVNLASMLEERLEVTLKKAHGAEDWSRRPLPHSWLVYAALDVEKLIPLAESMKLLL
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHEEHHHHHHHHHHHHHHHHHH
EAHGKLEWHKQECAHLINTSSHGLDTQRSWQDIKGVSRLTRPRQLVVAEALWELRDDEAR
HHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHH
MKNTSVSRLLPDKVLISVAQRPPRNSQAALRASEIPKQYRKRIARWMPTINDVLESDPRT
HHHCHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
WPHTPQFDENQLPSKYVWEKIHPESLDDFEEVKNSIVEKALLLNLPAENLMQPHSVKELC
CCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHH
WQLRDVPRPIAQDDVIECLMRLEARPWQIDNSASVITDTLNKIEHAS
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALLVTQPSEGLPPLAATSRSIYEAAYQLSQGTGPFAIDTERAGAYRYDDRAYLLQIRRE
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCEEEEEEEEC
GSGTVLIDPEANRRLVTSVLGKVINNQPWIIHAAATDLPCLSELGFYPSTIFDTELAGRL
CCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHH
AGLPRVNLASMLEERLEVTLKKAHGAEDWSRRPLPHSWLVYAALDVEKLIPLAESMKLLL
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHEEHHHHHHHHHHHHHHHHHH
EAHGKLEWHKQECAHLINTSSHGLDTQRSWQDIKGVSRLTRPRQLVVAEALWELRDDEAR
HHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHH
MKNTSVSRLLPDKVLISVAQRPPRNSQAALRASEIPKQYRKRIARWMPTINDVLESDPRT
HHHCHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
WPHTPQFDENQLPSKYVWEKIHPESLDDFEEVKNSIVEKALLLNLPAENLMQPHSVKELC
CCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHH
WQLRDVPRPIAQDDVIECLMRLEARPWQIDNSASVITDTLNKIEHAS
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]