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The map label for this gene is 38233972

Identifier: 38233972

GI number: 38233972

Start: 1403777

End: 1404361

Strand: Reverse

Name: 38233972

Synonym: DIP1387

Alternate gene names: NA

Gene position: 1404361-1403777 (Counterclockwise)

Preceding gene: 38233973

Following gene: 38233971

Centisome position: 56.43

GC content: 49.74

Gene sequence:

>585_bases
ATGGGGTCAGTGCCAGACAACGGTGAAACATACGTTGATCAAGGCATCGGCGTGGAAGATCGTCTAGAACGCCTATGGGC
GCCTTATCGAATGGCGTACATCAAGAAAGATCCCGTTGATGATGCACGTGGCTCTACCAACCCTTTTGTTCGGATCCCTG
AGCTGTCAGATGAAGATGGGCTCATCGTTGCGAGAGGGGAGTACGTTTACTGCCTTCTTAATCTCTTTCCTTACAACTCT
GGGCATATGATGGTTGTTCCTTATCGCCAAGAGCCCAATTTGGAAGACCTTACTGCCGAAGAAATTTCTGAACTTTTTGC
TTTTGGCCAAGCTGCGATCAAAGTTGTGAAATCAGTATCGCGCCCAGATGCTATCAACGTCGGGTTCAATTTGGGTCGTG
CATCGGGTGGCTCGGTGGGCGAACATCTCCATATGCACATTGTGCCGCGTTGGTCTGGAGACGCGAATTTTATGACTGTT
ATTGATGGGACAAAAGTATTGCCACAATTGTTGCGTAAGACGCGGTCGTTGCTCGCGCAAGCGTGGAACGACATGGACGG
AATCCCAGGAGTAGCTCATGCTTAG

Upstream 100 bases:

>100_bases
AAACGAAGTACGGTGTAGTAAGAAATTGAGATAGTTACAACAGTAAGATTCAATATTTGCTGTTGGACATTGTTATCTAA
TTGGTGGTTGAGGAGCAGAT

Downstream 100 bases:

>100_bases
TGTCCATGGCAGGAAACCTGCAGCGGTTATCGTCGAGCCTGTGGCAAAAGCACTGATCAAGATTGGTTTTACTCCTAATT
CCATCACCATCGTAGGTACC

Product: hypothetical protein

Products: NA

Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MGSVPDNGETYVDQGIGVEDRLERLWAPYRMAYIKKDPVDDARGSTNPFVRIPELSDEDGLIVARGEYVYCLLNLFPYNS
GHMMVVPYRQEPNLEDLTAEEISELFAFGQAAIKVVKSVSRPDAINVGFNLGRASGGSVGEHLHMHIVPRWSGDANFMTV
IDGTKVLPQLLRKTRSLLAQAWNDMDGIPGVAHA

Sequences:

>Translated_194_residues
MGSVPDNGETYVDQGIGVEDRLERLWAPYRMAYIKKDPVDDARGSTNPFVRIPELSDEDGLIVARGEYVYCLLNLFPYNS
GHMMVVPYRQEPNLEDLTAEEISELFAFGQAAIKVVKSVSRPDAINVGFNLGRASGGSVGEHLHMHIVPRWSGDANFMTV
IDGTKVLPQLLRKTRSLLAQAWNDMDGIPGVAHA
>Mature_193_residues
GSVPDNGETYVDQGIGVEDRLERLWAPYRMAYIKKDPVDDARGSTNPFVRIPELSDEDGLIVARGEYVYCLLNLFPYNSG
HMMVVPYRQEPNLEDLTAEEISELFAFGQAAIKVVKSVSRPDAINVGFNLGRASGGSVGEHLHMHIVPRWSGDANFMTVI
DGTKVLPQLLRKTRSLLAQAWNDMDGIPGVAHA

Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320511, Length=92, Percent_Identity=38.0434782608696, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: =2.7.7.53 [H]

Molecular weight: Translated: 21444; Mature: 21312

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSVPDNGETYVDQGIGVEDRLERLWAPYRMAYIKKDPVDDARGSTNPFVRIPELSDEDG
CCCCCCCCCCHHHCCCCHHHHHHHHCCHHHHEEEECCCCCCCCCCCCCEEECCCCCCCCC
LIVARGEYVYCLLNLFPYNSGHMMVVPYRQEPNLEDLTAEEISELFAFGQAAIKVVKSVS
EEEECCCEEEEEEEHEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
RPDAINVGFNLGRASGGSVGEHLHMHIVPRWSGDANFMTVIDGTKVLPQLLRKTRSLLAQ
CCCEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
AWNDMDGIPGVAHA
HHHCCCCCCCCCCC
>Mature Secondary Structure 
GSVPDNGETYVDQGIGVEDRLERLWAPYRMAYIKKDPVDDARGSTNPFVRIPELSDEDG
CCCCCCCCCHHHCCCCHHHHHHHHCCHHHHEEEECCCCCCCCCCCCCEEECCCCCCCCC
LIVARGEYVYCLLNLFPYNSGHMMVVPYRQEPNLEDLTAEEISELFAFGQAAIKVVKSVS
EEEECCCEEEEEEEHEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
RPDAINVGFNLGRASGGSVGEHLHMHIVPRWSGDANFMTVIDGTKVLPQLLRKTRSLLAQ
CCCEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
AWNDMDGIPGVAHA
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]