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The map label for this gene is insK [C]

Identifier: 38233952

GI number: 38233952

Start: 1382700

End: 1384079

Strand: Direct

Name: insK [C]

Synonym: DIP1366

Alternate gene names: 38233952

Gene position: 1382700-1384079 (Clockwise)

Preceding gene: 38233951

Following gene: 38233965

Centisome position: 55.56

GC content: 48.99

Gene sequence:

>1380_bases
ATGAACCGTTCCTACACCAACACGCAGAAGCGCACAGCACTGCGGGTCTACAAACGCACACAATCAGTGACTAAAACAGT
CCGCGAACTCGGCTACCCAGGCAGATGGACCCTGTATAAATGGCTACGCGAGCCCAAAACCCCACCACAACCACGTAAAC
AAGCCAAAACCCTGACCCACTACCCATACGAAGTCAAACTTCGCGCAGTAGAACTTTTCCACAATGGTTGGCGACCAGCT
GATATTGCCCAGGAATGCTGCCTGCACACTCACGCCAGCGTCTATGCTTGGGCGCAACGCTACCGTGAGGAAGGACAATG
GGGCTTGATGTCGAAAAAAGAACGCGCAGGCCATGGCCGCATCCCTACTAAAGCAGCACTAGAAAAATCATTGCCGGATA
ATCCAACACAGTTAAAACAGCAGATGGCCACGCTGCTGGTAGAAAAAGCCGTGTTGGAAAAGGAGCTGGAAATTATAAAA
AAAGACGTAAGCGTCATCCCCGGTCAGCTGAGTAATAAGCACAAAACCGACGTGGTTGACGCTTTGCGTAGCACGTTTCC
ATTAGCAATGCTGCTCGCTGCTAGTGGTCTTGCTGCATCCAGTTTCTATTACCACCTGAAAAAACGACGCATGCCTGATA
AGCACGCAGCTATTCGCAGCATGGTGCACCGCATCAGTTCTGATTCACATAATACCTATGGTTATCGCCGTATCTGGTGG
CAGTTACGACATTTAGGCATAACTATCAGTGAAAAAGTAGTTCGCAGGCTCATGCGCGAAGAAGCAATTACGGTGCGGTT
TCCGAAGCGGAAGGTGAAATATTCCAGTTATCAAGGAGAAATTTCTCCGGCTCCGCCGAACCTGGTCAACCGTTGTTTTC
ATGCCACTGCTGCGAATACGTTGTGGCTGACTGATATTAGTGTTTTCGCTGTGAATGAGGGGCGGGTGTATTTGTCTGTG
ATTATTGATTGTTTCGATGGCAAAGTCGTTGCTGCTAAGACGAGTGTGAATCCCACTATGGAGTTAGCAGAATCTACGCT
GCAGGCCGCTATTGATGCTGAGGGTCTTCCACCGGATGGTTCATTAGTGATTCATTCAGATCGTGGTGTGCATTACCGTG
GTCGGAGTTGGCATAGTCTGACTGCGAAATATGGCATCGTTCGTTCGATGTCGAAAAAGGGGTGTAGTCCTGACAATGCG
GCATGCGAGGGGTTTTTCGGGCGGATGAAAAATGAGATGTATTACGGCAAGAGGTGGCAGACAATCCAAGAGCTTGACGA
TGCCATTGCTGCTTATATCGAGTTTTATAACAATCATCGCATTAAAGTTAGTCTCAATGGTATGAGTATCGCGCGTTATC
GCATGGCTGCGGTAGCGTGA

Upstream 100 bases:

>100_bases
TTGGGATAGCCTTGTCGTAGAAGACTGGAAGTCCGGTTTTCTAGGTCGGCCGGCTTAAGGGACATTTGGGGATGCGGACG
AAATCTTGGAGGATTCCATT

Downstream 100 bases:

>100_bases
GGTTGAAAGTGTCTAACAAAACGTCCGCATCCCCAAATGTCCCTTAAGCCGGTCGGCCAACAGGATGTGATGGCACCGTA
GGCGCCTTGCCCACCATCGA

Product: putative transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAKTLTHYPYEVKLRAVELFHNGWRPA
DIAQECCLHTHASVYAWAQRYREEGQWGLMSKKERAGHGRIPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKELEIIK
KDVSVIPGQLSNKHKTDVVDALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHAAIRSMVHRISSDSHNTYGYRRIWW
QLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSSYQGEISPAPPNLVNRCFHATAANTLWLTDISVFAVNEGRVYLSV
IIDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDGSLVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCSPDNA
ACEGFFGRMKNEMYYGKRWQTIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMAAVA

Sequences:

>Translated_459_residues
MNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAKTLTHYPYEVKLRAVELFHNGWRPA
DIAQECCLHTHASVYAWAQRYREEGQWGLMSKKERAGHGRIPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKELEIIK
KDVSVIPGQLSNKHKTDVVDALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHAAIRSMVHRISSDSHNTYGYRRIWW
QLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSSYQGEISPAPPNLVNRCFHATAANTLWLTDISVFAVNEGRVYLSV
IIDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDGSLVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCSPDNA
ACEGFFGRMKNEMYYGKRWQTIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMAAVA
>Mature_459_residues
MNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAKTLTHYPYEVKLRAVELFHNGWRPA
DIAQECCLHTHASVYAWAQRYREEGQWGLMSKKERAGHGRIPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKELEIIK
KDVSVIPGQLSNKHKTDVVDALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHAAIRSMVHRISSDSHNTYGYRRIWW
QLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSSYQGEISPAPPNLVNRCFHATAANTLWLTDISVFAVNEGRVYLSV
IIDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDGSLVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCSPDNA
ACEGFFGRMKNEMYYGKRWQTIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMAAVA

Specific function: Probably involved in the transposition of insertion sequence IS1353 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=262, Percent_Identity=27.4809160305344, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1789981, Length=277, Percent_Identity=38.9891696750903, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1788405, Length=277, Percent_Identity=27.0758122743682, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787263, Length=277, Percent_Identity=27.0758122743682, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786753, Length=277, Percent_Identity=27.0758122743682, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786570, Length=277, Percent_Identity=27.0758122743682, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786490, Length=277, Percent_Identity=27.0758122743682, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337
- InterPro:   IPR002514 [H]

Pfam domain/function: PF00665 rve; PF01527 Transposase_8 [H]

EC number: NA

Molecular weight: Translated: 52444; Mature: 52444

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAKTLTH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHC
YPYEVKLRAVELFHNGWRPADIAQECCLHTHASVYAWAQRYREEGQWGLMSKKERAGHGR
CCEEEEHHHEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCC
IPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKELEIIKKDVSVIPGQLSNKHKTDVVD
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHAAIRSMVHRISSDSHNTYGYRRIWW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
QLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSSYQGEISPAPPNLVNRCFHATAANT
HHHHCCCCHHHHHHHHHHHHCCEEEECCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCE
LWLTDISVFAVNEGRVYLSVIIDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDG
EEEEEEEEEEEECCCEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCC
SLVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCSPDNAACEGFFGRMKNEMYYGKRWQ
CEEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHH
TIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMAAVA
HHHHHHHHHHHHHHHHCCCEEEEEECCCEEHHHHHHHCC
>Mature Secondary Structure
MNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAKTLTH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHC
YPYEVKLRAVELFHNGWRPADIAQECCLHTHASVYAWAQRYREEGQWGLMSKKERAGHGR
CCEEEEHHHEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCC
IPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKELEIIKKDVSVIPGQLSNKHKTDVVD
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHAAIRSMVHRISSDSHNTYGYRRIWW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
QLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSSYQGEISPAPPNLVNRCFHATAANT
HHHHCCCCHHHHHHHHHHHHCCEEEECCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCE
LWLTDISVFAVNEGRVYLSVIIDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDG
EEEEEEEEEEEECCCEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCC
SLVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCSPDNAACEGFFGRMKNEMYYGKRWQ
CEEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHH
TIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMAAVA
HHHHHHHHHHHHHHHHCCCEEEEEECCCEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755869; 12499211 [H]