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The map label for this gene is dop [H]

Identifier: 38233835

GI number: 38233835

Start: 1249490

End: 1251016

Strand: Reverse

Name: dop [H]

Synonym: DIP1247

Alternate gene names: 38233835

Gene position: 1251016-1249490 (Counterclockwise)

Preceding gene: 38233836

Following gene: 38233834

Centisome position: 50.27

GC content: 46.43

Gene sequence:

>1527_bases
ATGAGCAGATTTGTTGGTACAGAGACAGAATACGGAATAGCGACTCCGTCAAACACGATGCTGAGCCCTATCGTCACGTC
GACTCATGCAGTGGTGGCGTTTTCGTTGGGGGAGCGGTGTGCGTCTCAAGCTCGTTGGGACTTTTCAGAAGAATCACCAC
TAAGAGATCTTCGTGGCTTCGATTTACGTCGTTACCGCACAGTTCCGGTCGTGGATCCTCATGCTTTGGGCGTAGCTAAT
TCAGTTCTCATTAACGGAGGACGCTTTTATGTTGACCATGCTCACCCAGAGTATTCATCGCCTGAAACAAGTTCTGCTTT
CCAGGCGATGCTCTACGACGCCGCAGGTGACGTAGTAATGAATCGTGCAGTGGAACTTGTTGCTGAAAATTCCCAGCGTA
AGCATTCGGTGTTAGAACATCATGATCCGTGTCCACCATTAAAAATTTATAAAAACAATGTGGATGGTAAAGGCGCCAGC
TATGGTAGCCACGAAAATTACCTCTATAATCGCGAAACTCCTTTTGAAGAGATTTCTTCAGGTTTGACTCCCTTTTTCAT
TACTCGGCAAGTAATCATTGGAGCGGGTCGAGTTGGAATAGGGCAATATGGCGAAAAATCTGGTTTCCAGATTAGCCAAC
GTGCTGATTATATTGAGCAAGAAATTTCACTGGAAACAACGCTTAATCGTGGCATTATCAATACCCGCGATGAACCGCAT
GCAGATAGTGAACATTTTGGTCGCCTGCATGTCATCATCGGTGATGCCAATATGTCGCAAACTTCTAATTTTTTGAAAAT
TGGCATGACTACTTTAGTACTCGACGCAATTGAAGCTGGAGTTGATTTTTCTGACCTCGCGGTTGCCAATCCGGTCGCAG
AGGTAAGTGCGATTTCACATGATCTCACGCTTACGCACAAAATTGTCCTTCGCGATGGAAGAACTTTGACGGCACTCGAG
CTCCTCGACGAGTACCGCAAACGCGTATCTCCACAGTCAGATGACGATCTTGACGTTTTGAAGGAATGGTCTGAGATACT
AGTTTTGCTGCAAAAGGGACCTTTCTATGCTGCCGACCGACTTGACTGGTGTGCCAAGTGGCAGCTTATTTCTTCATTCA
TTAAGCGTGGAGTATCGATTGATGATCCTAAGATTCAGCTCATCGATCTGCAGTACGCCGATATTGATCCGGCTAAAAGC
CTTTATCATGCGCTCGTCCGCAAAGGTCGCATGAGAACTCTAGTCTCTACCGAGCAGATTAATAATGCTGCTTGGTCACC
GCCAAAAGGTAGCCGTGCTTATTTACGGGGCAGCCTAATCTCACGTTTTCCTGACAGCGTCGTCCAAGCAAGTTGGGATT
CCATCACACTTCAAACGTCTCGTGATCAAGCTACAAAAATCAAAATGCCAGTGGTTCAATCACTGTCCGCGGAAGCAATC
GCTACCATCGACACGGCTTCTTCAGTCAAAGAGGTTGCCACTATTTTGTCTCAGTGGTTACCGGTCACAACTATTTCCTT
GACATAA

Upstream 100 bases:

>100_bases
GTGAAGACTTGCCGAATACATCTAATCCTGATGATTGGAGTCGTATCATCGGCCGCCATGGACTTCGAGTAGCACACGCC
CGAGTACTGGGAGGACAACG

Downstream 100 bases:

>100_bases
AACTTTGTTTTCATGCAAGGGTACGCTAATAACTTAGATCTTTAAGGAGCAATCATTATGAACCAGAACGGTAGCCAAAT
TCATTCCGACGGCAATGGAC

Product: hypothetical protein

Products: NA

Alternate protein names: Deamidase of protein Pup [H]

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MSRFVGTETEYGIATPSNTMLSPIVTSTHAVVAFSLGERCASQARWDFSEESPLRDLRGFDLRRYRTVPVVDPHALGVAN
SVLINGGRFYVDHAHPEYSSPETSSAFQAMLYDAAGDVVMNRAVELVAENSQRKHSVLEHHDPCPPLKIYKNNVDGKGAS
YGSHENYLYNRETPFEEISSGLTPFFITRQVIIGAGRVGIGQYGEKSGFQISQRADYIEQEISLETTLNRGIINTRDEPH
ADSEHFGRLHVIIGDANMSQTSNFLKIGMTTLVLDAIEAGVDFSDLAVANPVAEVSAISHDLTLTHKIVLRDGRTLTALE
LLDEYRKRVSPQSDDDLDVLKEWSEILVLLQKGPFYAADRLDWCAKWQLISSFIKRGVSIDDPKIQLIDLQYADIDPAKS
LYHALVRKGRMRTLVSTEQINNAAWSPPKGSRAYLRGSLISRFPDSVVQASWDSITLQTSRDQATKIKMPVVQSLSAEAI
ATIDTASSVKEVATILSQWLPVTTISLT

Sequences:

>Translated_508_residues
MSRFVGTETEYGIATPSNTMLSPIVTSTHAVVAFSLGERCASQARWDFSEESPLRDLRGFDLRRYRTVPVVDPHALGVAN
SVLINGGRFYVDHAHPEYSSPETSSAFQAMLYDAAGDVVMNRAVELVAENSQRKHSVLEHHDPCPPLKIYKNNVDGKGAS
YGSHENYLYNRETPFEEISSGLTPFFITRQVIIGAGRVGIGQYGEKSGFQISQRADYIEQEISLETTLNRGIINTRDEPH
ADSEHFGRLHVIIGDANMSQTSNFLKIGMTTLVLDAIEAGVDFSDLAVANPVAEVSAISHDLTLTHKIVLRDGRTLTALE
LLDEYRKRVSPQSDDDLDVLKEWSEILVLLQKGPFYAADRLDWCAKWQLISSFIKRGVSIDDPKIQLIDLQYADIDPAKS
LYHALVRKGRMRTLVSTEQINNAAWSPPKGSRAYLRGSLISRFPDSVVQASWDSITLQTSRDQATKIKMPVVQSLSAEAI
ATIDTASSVKEVATILSQWLPVTTISLT
>Mature_507_residues
SRFVGTETEYGIATPSNTMLSPIVTSTHAVVAFSLGERCASQARWDFSEESPLRDLRGFDLRRYRTVPVVDPHALGVANS
VLINGGRFYVDHAHPEYSSPETSSAFQAMLYDAAGDVVMNRAVELVAENSQRKHSVLEHHDPCPPLKIYKNNVDGKGASY
GSHENYLYNRETPFEEISSGLTPFFITRQVIIGAGRVGIGQYGEKSGFQISQRADYIEQEISLETTLNRGIINTRDEPHA
DSEHFGRLHVIIGDANMSQTSNFLKIGMTTLVLDAIEAGVDFSDLAVANPVAEVSAISHDLTLTHKIVLRDGRTLTALEL
LDEYRKRVSPQSDDDLDVLKEWSEILVLLQKGPFYAADRLDWCAKWQLISSFIKRGVSIDDPKIQLIDLQYADIDPAKSL
YHALVRKGRMRTLVSTEQINNAAWSPPKGSRAYLRGSLISRFPDSVVQASWDSITLQTSRDQATKIKMPVVQSLSAEAIA
TIDTASSVKEVATILSQWLPVTTISLT

Specific function: Specifically catalyzes the deamidation of the C-terminal glutamine of the prokaryotic ubiquitin-like protein Pup to glutamate, thereby rendering Pup competent for conjugation. Also displays depupylase (DPUP) activity, removing conjugated Pup from target p

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022366
- InterPro:   IPR004347 [H]

Pfam domain/function: PF03136 DUF245 [H]

EC number: NA

Molecular weight: Translated: 56285; Mature: 56154

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFVGTETEYGIATPSNTMLSPIVTSTHAVVAFSLGERCASQARWDFSEESPLRDLRGF
CCCCCCCCCCCCCCCCCCCHHHHHHHCCHHEEEEHHHHHHHHHCCCCCCCCCCHHHHCCC
DLRRYRTVPVVDPHALGVANSVLINGGRFYVDHAHPEYSSPETSSAFQAMLYDAAGDVVM
CCHHEEECCCCCCHHHCCCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
NRAVELVAENSQRKHSVLEHHDPCPPLKIYKNNVDGKGASYGSHENYLYNRETPFEEISS
HHHHHHHHCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCCHHHHHC
GLTPFFITRQVIIGAGRVGIGQYGEKSGFQISQRADYIEQEISLETTLNRGIINTRDEPH
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ADSEHFGRLHVIIGDANMSQTSNFLKIGMTTLVLDAIEAGVDFSDLAVANPVAEVSAISH
CCHHHCCEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHC
DLTLTHKIVLRDGRTLTALELLDEYRKRVSPQSDDDLDVLKEWSEILVLLQKGPFYAADR
CCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
LDWCAKWQLISSFIKRGVSIDDPKIQLIDLQYADIDPAKSLYHALVRKGRMRTLVSTEQI
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHH
NNAAWSPPKGSRAYLRGSLISRFPDSVVQASWDSITLQTSRDQATKIKMPVVQSLSAEAI
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCEEEEEECCCCHHEECHHHHHHCCCCCE
ATIDTASSVKEVATILSQWLPVTTISLT
EEHHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure 
SRFVGTETEYGIATPSNTMLSPIVTSTHAVVAFSLGERCASQARWDFSEESPLRDLRGF
CCCCCCCCCCCCCCCCCCHHHHHHHCCHHEEEEHHHHHHHHHCCCCCCCCCCHHHHCCC
DLRRYRTVPVVDPHALGVANSVLINGGRFYVDHAHPEYSSPETSSAFQAMLYDAAGDVVM
CCHHEEECCCCCCHHHCCCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
NRAVELVAENSQRKHSVLEHHDPCPPLKIYKNNVDGKGASYGSHENYLYNRETPFEEISS
HHHHHHHHCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCCHHHHHC
GLTPFFITRQVIIGAGRVGIGQYGEKSGFQISQRADYIEQEISLETTLNRGIINTRDEPH
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ADSEHFGRLHVIIGDANMSQTSNFLKIGMTTLVLDAIEAGVDFSDLAVANPVAEVSAISH
CCHHHCCEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHC
DLTLTHKIVLRDGRTLTALELLDEYRKRVSPQSDDDLDVLKEWSEILVLLQKGPFYAADR
CCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
LDWCAKWQLISSFIKRGVSIDDPKIQLIDLQYADIDPAKSLYHALVRKGRMRTLVSTEQI
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHH
NNAAWSPPKGSRAYLRGSLISRFPDSVVQASWDSITLQTSRDQATKIKMPVVQSLSAEAI
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCEEEEEECCCCHHEECHHHHHHCCCCCE
ATIDTASSVKEVATILSQWLPVTTISLT
EEHHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7583123 [H]