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The map label for this gene is glgB

Identifier: 38233659

GI number: 38233659

Start: 1043761

End: 1045959

Strand: Reverse

Name: glgB

Synonym: DIP1065

Alternate gene names: 38233659

Gene position: 1045959-1043761 (Counterclockwise)

Preceding gene: 38233660

Following gene: 38233657

Centisome position: 42.03

GC content: 54.34

Gene sequence:

>2199_bases
ATGGTTTCTCCTACTCAGATCACACCAGTCCATCCTGATGTCCTCCACGCCCTCAAAATCTGCCAGTACCACGATCCGCA
CGGAGTATATGGCTGGCACGAGGTAGATGCTGAACGCGCAGTTATCCGTACCCGCCACATCGGAGCAGAACGCGTGGAAA
CATTACTCAGCGACTCCACTGTGGTAGAGCTCGCCGCCGTAGGTGACGACATCTTTGAAGCAATCGTTGACCACGATGCT
TCCTGCGATTATCGCCTACGAATTCACTGGCAAGGTGGACAAGTAACCGAGCAAGCCGATGCATACCATTTCCTGCCAAC
GCTAGGTGATCTTGACCTCCACCTCATCAACGAAGGCCGTCATGAGCGACTTTGGGAAGTACTCGGCGCAAACCCGACCA
CTATCACCACGGCCATGGGTGACGTTGAAGGTACTGCCTTTGCAGTCTGGGCACCTAACGCAAGCGGAGTTGCTGTCATC
GGCGACTTCTGCGGATGGAACCCCAGCCAATACCCTATGCGTAGCCTCGGCTCGACCGGAATCTGGGAGCTGTTCATCCC
TAACATTGGCGTGGGAACAGTCTACAAATTTGCGATCCACACCCACGAAGGTCATCGTCTCGACAAGGCAGACCCCATGG
CAAAGCGTGCCGAGGTAGCACCGGCAACCGGCTCTATCATCGCTTCCTCCTCCTACACGTGGAATGACGATACATGGATG
ACCAATCGTGCGCACACCGACCACGACAACACTGCGATGAGCGTCTACGAGGTCCATCTTGGTTCATGGAGCCAAGGCCA
AAACTACGAGGAACTAGCCACCAACCTTGTCGACTATGTCAAGGAAATGGGCTATACCCACGTGGAGTTCCTCCCTGTAG
CAGAGCACCCCTTTGGTGGTTCATGGGGCTACCAAGTTTCTGGTTACTACGCTCCTACCTCGCGCTGGGGTACCCCAGAT
CAGCTTCGCTTGCTTATCGACGCCTTCCACCAAGCAGGCATCGGCGTAATCGTCGACTGGGTACCAGCACACTTCCCCAA
AGATGCCTTTGCACTCGGCCGCTTCGATGGTCAAGCTCTTTACGAACACCCTGACTGGCGCCGCGGTGAACAAAAAGACT
GGGGCACCTACGTTTTCGATTTCGGCCGCAACGAAGTCCGCAACTTCCTCGTCGCCAACGCTTTGTACTGGCTCGAAGAG
TTCCATGTCGATGGACTCCGTGTCGATGCTGTGGCCTCCATGCTGTATTTGGACTACTCACGCGAACCCGGTGAGTGGCT
TCCTAACATCTACGGTGGCCGTGAAAACCTCGAAGCTGTTCAGTTCCTCCAAGAAATGAACGCCACCGTGCACAAGAGCC
ACCCAGGCGTGATGACCATTGCTGAAGAATCCACCTCATGGCCAGGAGTTACCTCTCCAACGTGGGAAGGCGGCCTCGGT
TTCAGCATGAAATGGAACATGGGCTGGATGAATGACACACTCGAATACTTCTCACACGAGCCTATTCATCGCATGTACCA
CCACAACGACATCACATTCTCCATGGTGTACGCATACTCTGAGAAATTCGTGCTCCCCTTCAGCCACGACGAAGTAGTTC
ACGGCAAAGGCTCGCTGTGGACTCGAATGCCAGGCGACGCATGGAACAAAGCAGCGGGTCTACGCACCTTGTATGCCTAC
ATGTACGCTCACCCAGGCAAGAATCTGCTGTTCCAGGGACAAGAATTCGGCCAAGTGAAAGAATGGTCCGAAGAACGAAG
CCTTGACTGGGGTGACATGGACGGTTGGGAAGGCGAATACCACCGCGGTATCCGCACCCTAGTGCAAGACCTCAACGCAC
TGTACAAAGACTCCCCTGCGCTCTACAGCCAAGACAACAACCCAGCAGGATTTAGCTGGACAAAGTCTGACGACGCAGCA
AACAACATCTTGTCTTTCGTGCGCTACGGTGCTGATGGATCCAAGATCCTAGCTGTATTCAACTTTGGTGGAGCAGATCA
CCCAAGCTACAAATTAGGTGTGCCTGAAGGCGGAAACTGGAAGTGCATCCTCAACACTGATGCAGGCATCTACGAAGGAG
AAGACAACTACCTCGACAGCGACGTCATGGCGTGGGACACCGACTGGGATGGCTATCAGCATTCCCTCACAGTGCATATA
CCTGCAATGAGCGGCCAGCTCTATCGTTGGGAAGCATAA

Upstream 100 bases:

>100_bases
CAAAGCGCAACTATCGTGGCGCGGAGAATCCGATTATCGGAACTAATAACAGTCAACATCCGCCTCATATCGACTTAACG
TAAAGAAAGTACTTACTCTC

Downstream 100 bases:

>100_bases
TCACGCTGTTGTAAGAAGGTACGTTGCCGACCAGCATCAAACTGGCCGGCAACGTACCGTTCTCGCTTTTACTAGTTACT
ACCCGCGCTTTTCTTAAAAA

Product: glycogen branching enzyme

Products: NA

Alternate protein names: 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase; Glycogen-branching enzyme; BE

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MVSPTQITPVHPDVLHALKICQYHDPHGVYGWHEVDAERAVIRTRHIGAERVETLLSDSTVVELAAVGDDIFEAIVDHDA
SCDYRLRIHWQGGQVTEQADAYHFLPTLGDLDLHLINEGRHERLWEVLGANPTTITTAMGDVEGTAFAVWAPNASGVAVI
GDFCGWNPSQYPMRSLGSTGIWELFIPNIGVGTVYKFAIHTHEGHRLDKADPMAKRAEVAPATGSIIASSSYTWNDDTWM
TNRAHTDHDNTAMSVYEVHLGSWSQGQNYEELATNLVDYVKEMGYTHVEFLPVAEHPFGGSWGYQVSGYYAPTSRWGTPD
QLRLLIDAFHQAGIGVIVDWVPAHFPKDAFALGRFDGQALYEHPDWRRGEQKDWGTYVFDFGRNEVRNFLVANALYWLEE
FHVDGLRVDAVASMLYLDYSREPGEWLPNIYGGRENLEAVQFLQEMNATVHKSHPGVMTIAEESTSWPGVTSPTWEGGLG
FSMKWNMGWMNDTLEYFSHEPIHRMYHHNDITFSMVYAYSEKFVLPFSHDEVVHGKGSLWTRMPGDAWNKAAGLRTLYAY
MYAHPGKNLLFQGQEFGQVKEWSEERSLDWGDMDGWEGEYHRGIRTLVQDLNALYKDSPALYSQDNNPAGFSWTKSDDAA
NNILSFVRYGADGSKILAVFNFGGADHPSYKLGVPEGGNWKCILNTDAGIYEGEDNYLDSDVMAWDTDWDGYQHSLTVHI
PAMSGQLYRWEA

Sequences:

>Translated_732_residues
MVSPTQITPVHPDVLHALKICQYHDPHGVYGWHEVDAERAVIRTRHIGAERVETLLSDSTVVELAAVGDDIFEAIVDHDA
SCDYRLRIHWQGGQVTEQADAYHFLPTLGDLDLHLINEGRHERLWEVLGANPTTITTAMGDVEGTAFAVWAPNASGVAVI
GDFCGWNPSQYPMRSLGSTGIWELFIPNIGVGTVYKFAIHTHEGHRLDKADPMAKRAEVAPATGSIIASSSYTWNDDTWM
TNRAHTDHDNTAMSVYEVHLGSWSQGQNYEELATNLVDYVKEMGYTHVEFLPVAEHPFGGSWGYQVSGYYAPTSRWGTPD
QLRLLIDAFHQAGIGVIVDWVPAHFPKDAFALGRFDGQALYEHPDWRRGEQKDWGTYVFDFGRNEVRNFLVANALYWLEE
FHVDGLRVDAVASMLYLDYSREPGEWLPNIYGGRENLEAVQFLQEMNATVHKSHPGVMTIAEESTSWPGVTSPTWEGGLG
FSMKWNMGWMNDTLEYFSHEPIHRMYHHNDITFSMVYAYSEKFVLPFSHDEVVHGKGSLWTRMPGDAWNKAAGLRTLYAY
MYAHPGKNLLFQGQEFGQVKEWSEERSLDWGDMDGWEGEYHRGIRTLVQDLNALYKDSPALYSQDNNPAGFSWTKSDDAA
NNILSFVRYGADGSKILAVFNFGGADHPSYKLGVPEGGNWKCILNTDAGIYEGEDNYLDSDVMAWDTDWDGYQHSLTVHI
PAMSGQLYRWEA
>Mature_732_residues
MVSPTQITPVHPDVLHALKICQYHDPHGVYGWHEVDAERAVIRTRHIGAERVETLLSDSTVVELAAVGDDIFEAIVDHDA
SCDYRLRIHWQGGQVTEQADAYHFLPTLGDLDLHLINEGRHERLWEVLGANPTTITTAMGDVEGTAFAVWAPNASGVAVI
GDFCGWNPSQYPMRSLGSTGIWELFIPNIGVGTVYKFAIHTHEGHRLDKADPMAKRAEVAPATGSIIASSSYTWNDDTWM
TNRAHTDHDNTAMSVYEVHLGSWSQGQNYEELATNLVDYVKEMGYTHVEFLPVAEHPFGGSWGYQVSGYYAPTSRWGTPD
QLRLLIDAFHQAGIGVIVDWVPAHFPKDAFALGRFDGQALYEHPDWRRGEQKDWGTYVFDFGRNEVRNFLVANALYWLEE
FHVDGLRVDAVASMLYLDYSREPGEWLPNIYGGRENLEAVQFLQEMNATVHKSHPGVMTIAEESTSWPGVTSPTWEGGLG
FSMKWNMGWMNDTLEYFSHEPIHRMYHHNDITFSMVYAYSEKFVLPFSHDEVVHGKGSLWTRMPGDAWNKAAGLRTLYAY
MYAHPGKNLLFQGQEFGQVKEWSEERSLDWGDMDGWEGEYHRGIRTLVQDLNALYKDSPALYSQDNNPAGFSWTKSDDAA
NNILSFVRYGADGSKILAVFNFGGADHPSYKLGVPEGGNWKCILNTDAGIYEGEDNYLDSDVMAWDTDWDGYQHSLTVHI
PAMSGQLYRWEA

Specific function: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position

COG id: COG0296

COG function: function code G; 1,4-alpha-glucan branching enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family

Homologues:

Organism=Homo sapiens, GI189458812, Length=630, Percent_Identity=29.3650793650794, Blast_Score=194, Evalue=3e-49,
Organism=Escherichia coli, GI1789839, Length=732, Percent_Identity=44.672131147541, Blast_Score=603, Evalue=1e-173,
Organism=Escherichia coli, GI2367229, Length=299, Percent_Identity=25.4180602006689, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554896, Length=624, Percent_Identity=27.0833333333333, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI32564391, Length=594, Percent_Identity=26.7676767676768, Blast_Score=158, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6320826, Length=653, Percent_Identity=25.5742725880551, Blast_Score=170, Evalue=6e-43,
Organism=Drosophila melanogaster, GI28573410, Length=642, Percent_Identity=26.9470404984424, Blast_Score=182, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLGB_CORDI (Q6NHR6)

Other databases:

- EMBL:   BX248357
- RefSeq:   NP_939426.1
- ProteinModelPortal:   Q6NHR6
- SMR:   Q6NHR6
- GeneID:   2649325
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1065
- NMPDR:   fig|257309.1.peg.1017
- HOGENOM:   HBG287139
- OMA:   DGTCLYE
- PhylomeDB:   Q6NHR6
- ProtClustDB:   PRK05402
- BioCyc:   CDIP257309:DIP1065-MONOMER
- BRENDA:   2.4.1.18
- HAMAP:   MF_00685
- InterPro:   IPR006407
- InterPro:   IPR006048
- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004193
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756
- Gene3D:   G3DSA:2.60.40.1180
- Gene3D:   G3DSA:3.20.20.80
- Gene3D:   G3DSA:2.60.40.10
- TIGRFAMs:   TIGR01515

Pfam domain/function: PF00128 Alpha-amylase; PF02806 Alpha-amylase_C; PF02922 CBM_48; SSF51445 Glyco_hydro_cat; SSF81296 Ig_E-set

EC number: =2.4.1.18

Molecular weight: Translated: 82603; Mature: 82603

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: ACT_SITE 304-304 ACT_SITE 339-339 ACT_SITE 344-344 ACT_SITE 407-407 ACT_SITE 409-409 ACT_SITE 462-462 ACT_SITE 529-529 ACT_SITE 530-530

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSPTQITPVHPDVLHALKICQYHDPHGVYGWHEVDAERAVIRTRHIGAERVETLLSDST
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHCCHHHHHHHHCCCC
VVELAAVGDDIFEAIVDHDASCDYRLRIHWQGGQVTEQADAYHFLPTLGDLDLHLINEGR
EEEEEHHCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCCCEEEEECCCH
HERLWEVLGANPTTITTAMGDVEGTAFAVWAPNASGVAVIGDFCGWNPSQYPMRSLGSTG
HHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHCCCCC
IWELFIPNIGVGTVYKFAIHTHEGHRLDKADPMAKRAEVAPATGSIIASSSYTWNDDTWM
EEEEECCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCEEECCCCEECCCCEE
TNRAHTDHDNTAMSVYEVHLGSWSQGQNYEELATNLVDYVKEMGYTHVEFLPVAEHPFGG
CCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
SWGYQVSGYYAPTSRWGTPDQLRLLIDAFHQAGIGVIVDWVPAHFPKDAFALGRFDGQAL
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHEECCCCCCCC
YEHPDWRRGEQKDWGTYVFDFGRNEVRNFLVANALYWLEEFHVDGLRVDAVASMLYLDYS
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHEECC
REPGEWLPNIYGGRENLEAVQFLQEMNATVHKSHPGVMTIAEESTSWPGVTSPTWEGGLG
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCCCCCCCCCCCC
FSMKWNMGWMNDTLEYFSHEPIHRMYHHNDITFSMVYAYSEKFVLPFSHDEVVHGKGSLW
EEEEECCCCHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCCEEEECCCCCEEECCCCEE
TRMPGDAWNKAAGLRTLYAYMYAHPGKNLLFQGQEFGQVKEWSEERSLDWGDMDGWEGEY
ECCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHH
HRGIRTLVQDLNALYKDSPALYSQDNNPAGFSWTKSDDAANNILSFVRYGADGSKILAVF
HHHHHHHHHHHHHHHCCCCCEECCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCEEEEEE
NFGGADHPSYKLGVPEGGNWKCILNTDAGIYEGEDNYLDSDVMAWDTDWDGYQHSLTVHI
ECCCCCCCCEEECCCCCCCEEEEEECCCCEECCCCCCCCCCCEEECCCCCCCEEEEEEEE
PAMSGQLYRWEA
ECCCCCEEEECC
>Mature Secondary Structure
MVSPTQITPVHPDVLHALKICQYHDPHGVYGWHEVDAERAVIRTRHIGAERVETLLSDST
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHCCHHHHHHHHCCCC
VVELAAVGDDIFEAIVDHDASCDYRLRIHWQGGQVTEQADAYHFLPTLGDLDLHLINEGR
EEEEEHHCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCCCEEEEECCCH
HERLWEVLGANPTTITTAMGDVEGTAFAVWAPNASGVAVIGDFCGWNPSQYPMRSLGSTG
HHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHCCCCC
IWELFIPNIGVGTVYKFAIHTHEGHRLDKADPMAKRAEVAPATGSIIASSSYTWNDDTWM
EEEEECCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCEEECCCCEECCCCEE
TNRAHTDHDNTAMSVYEVHLGSWSQGQNYEELATNLVDYVKEMGYTHVEFLPVAEHPFGG
CCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
SWGYQVSGYYAPTSRWGTPDQLRLLIDAFHQAGIGVIVDWVPAHFPKDAFALGRFDGQAL
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHEECCCCCCCC
YEHPDWRRGEQKDWGTYVFDFGRNEVRNFLVANALYWLEEFHVDGLRVDAVASMLYLDYS
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHEECC
REPGEWLPNIYGGRENLEAVQFLQEMNATVHKSHPGVMTIAEESTSWPGVTSPTWEGGLG
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCCCCCCCCCCCC
FSMKWNMGWMNDTLEYFSHEPIHRMYHHNDITFSMVYAYSEKFVLPFSHDEVVHGKGSLW
EEEEECCCCHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCCEEEECCCCCEEECCCCEE
TRMPGDAWNKAAGLRTLYAYMYAHPGKNLLFQGQEFGQVKEWSEERSLDWGDMDGWEGEY
ECCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHH
HRGIRTLVQDLNALYKDSPALYSQDNNPAGFSWTKSDDAANNILSFVRYGADGSKILAVF
HHHHHHHHHHHHHHHCCCCCEECCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCEEEEEE
NFGGADHPSYKLGVPEGGNWKCILNTDAGIYEGEDNYLDSDVMAWDTDWDGYQHSLTVHI
ECCCCCCCCEEECCCCCCCEEEEEECCCCEECCCCCCCCCCCEEECCCCCCCEEEEEEEE
PAMSGQLYRWEA
ECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14602910