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The map label for this gene is lutB [H]

Identifier: 38233626

GI number: 38233626

Start: 1009343

End: 1010860

Strand: Reverse

Name: lutB [H]

Synonym: DIP1031

Alternate gene names: 38233626

Gene position: 1010860-1009343 (Counterclockwise)

Preceding gene: 38233627

Following gene: 38233625

Centisome position: 40.62

GC content: 56.13

Gene sequence:

>1518_bases
ATGCCACCACGCGCATCGGAGCGCAGCCAGCTGCGCGGTGACGAGAACTTCGTCCACGCCGCTCACCATGAGCTATACAA
TGCAACCCAGCGCCGAAACCTCACCAAGGCAACGACCACCATTCGCACCAAGCGTCTGAACGTCACCGCTGAGATGCCTG
ACTGGGAGGCAGTACGCGAAGCTGGTTCCGGTATTAAGCGCGATGTCGGACAGCGTCTCGACGAGCTGCTCGTTCAGTTC
GAAGAAGCCGTAACTGCCCGCGGTGGCCACGTCCACTGGGCACGCGACGCCAAAGAAGCAGGCGACATCGTTACCAAGCT
GGTTGAAGAAACCGGTGAGAAAAACGTTGTCAAGATCAAGTCCATGGCAACCATGGAAATTGACCTCAACAACCGCCTCC
GCGAAGCTGGCATTTCCGCCCGTGAAACCGACTTGGCTGAGCTTATCGTTCAGCTGGGCAAAGACAAGCCATCTCACATT
CTGGTTCCGGCAATTCACCGCAACCGCGCCGAGATCCGCGACATCTTCATTCGCGAAATGCCCAACACCGACGACTCCCT
TTCTTCCGAACCTGCAGAGTTGGCAGAAGCATCCCGCTCCTTCCTACGCGAGCAGTTCATGAAGGCAAAGGTTGCCATTT
CAGGAGCCAACTTCGGTATCGCTGAAACCGGCACCGTGACCATCATGGAGTCTGAAGGCAACGGCCGTATGTGCCTGACC
CTTCCTGAAACCCTGATCTCCGTCATGGGTATCGAGAAGATCATCCCAACCTTCCAAGACCTCGAGGTCTTCTTGCAGCT
GCTGCCACGTTCTTCCACCGGCGAGCGCCAGGCACCATACGTTTCCACTTGGTCCGGCGTTACCGAGGGTGACGGCCCGA
AGAACTTCCACATCGTGCTCGTTGATAACGGCCGTACCGCAGTACTCTCCGACGAGATCGGCCGTGAAGCACTCAAGTGC
ATCCGTTGCTCTGCATGTTTGAACGTATGCCCAGTCTACGAACGCGCTGGTGGCCACGCTTACGGTTCGACCTACCCAGG
TCCTATCGGCGCCATCTTGTCCCCACAGATGACCGGTATCAAGAATAAGCATGATCCAAATGCTTACCTGCCATACGCTT
CTTCCCTATGCGGTCGCTGCAATGAGGTTTGCCCAGTGAAGATTCCATTCACTGACATCCTTCTCGAGCTGCGCCACAAG
AAGATTCAAACCGACGCTCCAAAGATTGAGAAAGCCATGATGGGCGCTATGCAGCTCGCATGGGGCAACTCAACCATGTG
GAACATGATCACTCGCATGGTATTCATGGGTCGCATCATGGGCGGCTCAAACGGCAAGATCACCCACCTGCCAAGCTTTT
TGGCTGGTTGGACAGACGTTCGCGACACCGCAGTCCCACCGAAGAAGTCCTTCCGCCAGTGGTTCGAAACCGAGGAAGCA
CAACAGTTGCTTGCCGACGCTCGCCGCGACGGCATCCACCCAAATAATCCAGAAGTTAACCAGAAGAAGGAGAACTGA

Upstream 100 bases:

>100_bases
CTGAGATTCTTGCCTCCACCAAGGAAAATCCTTGGACCCCGACCACTGCCGCTTACTCCCGAGAGGTCATGCTGTGAGTA
TTTCACTTGGAACCCCAGCG

Downstream 100 bases:

>100_bases
GATGGATGCCAAAACCGAGATCCTCGAGCGTATCCGTAACGCCAACAAGCTAGCCAAGGCTCCTGAGGGCGCATACCCAG
TTGTCCGCGAATACATCACG

Product: putative iron-sulfur protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MPPRASERSQLRGDENFVHAAHHELYNATQRRNLTKATTTIRTKRLNVTAEMPDWEAVREAGSGIKRDVGQRLDELLVQF
EEAVTARGGHVHWARDAKEAGDIVTKLVEETGEKNVVKIKSMATMEIDLNNRLREAGISARETDLAELIVQLGKDKPSHI
LVPAIHRNRAEIRDIFIREMPNTDDSLSSEPAELAEASRSFLREQFMKAKVAISGANFGIAETGTVTIMESEGNGRMCLT
LPETLISVMGIEKIIPTFQDLEVFLQLLPRSSTGERQAPYVSTWSGVTEGDGPKNFHIVLVDNGRTAVLSDEIGREALKC
IRCSACLNVCPVYERAGGHAYGSTYPGPIGAILSPQMTGIKNKHDPNAYLPYASSLCGRCNEVCPVKIPFTDILLELRHK
KIQTDAPKIEKAMMGAMQLAWGNSTMWNMITRMVFMGRIMGGSNGKITHLPSFLAGWTDVRDTAVPPKKSFRQWFETEEA
QQLLADARRDGIHPNNPEVNQKKEN

Sequences:

>Translated_505_residues
MPPRASERSQLRGDENFVHAAHHELYNATQRRNLTKATTTIRTKRLNVTAEMPDWEAVREAGSGIKRDVGQRLDELLVQF
EEAVTARGGHVHWARDAKEAGDIVTKLVEETGEKNVVKIKSMATMEIDLNNRLREAGISARETDLAELIVQLGKDKPSHI
LVPAIHRNRAEIRDIFIREMPNTDDSLSSEPAELAEASRSFLREQFMKAKVAISGANFGIAETGTVTIMESEGNGRMCLT
LPETLISVMGIEKIIPTFQDLEVFLQLLPRSSTGERQAPYVSTWSGVTEGDGPKNFHIVLVDNGRTAVLSDEIGREALKC
IRCSACLNVCPVYERAGGHAYGSTYPGPIGAILSPQMTGIKNKHDPNAYLPYASSLCGRCNEVCPVKIPFTDILLELRHK
KIQTDAPKIEKAMMGAMQLAWGNSTMWNMITRMVFMGRIMGGSNGKITHLPSFLAGWTDVRDTAVPPKKSFRQWFETEEA
QQLLADARRDGIHPNNPEVNQKKEN
>Mature_504_residues
PPRASERSQLRGDENFVHAAHHELYNATQRRNLTKATTTIRTKRLNVTAEMPDWEAVREAGSGIKRDVGQRLDELLVQFE
EAVTARGGHVHWARDAKEAGDIVTKLVEETGEKNVVKIKSMATMEIDLNNRLREAGISARETDLAELIVQLGKDKPSHIL
VPAIHRNRAEIRDIFIREMPNTDDSLSSEPAELAEASRSFLREQFMKAKVAISGANFGIAETGTVTIMESEGNGRMCLTL
PETLISVMGIEKIIPTFQDLEVFLQLLPRSSTGERQAPYVSTWSGVTEGDGPKNFHIVLVDNGRTAVLSDEIGREALKCI
RCSACLNVCPVYERAGGHAYGSTYPGPIGAILSPQMTGIKNKHDPNAYLPYASSLCGRCNEVCPVKIPFTDILLELRHKK
IQTDAPKIEKAMMGAMQLAWGNSTMWNMITRMVFMGRIMGGSNGKITHLPSFLAGWTDVRDTAVPPKKSFRQWFETEEAQ
QLLADARRDGIHPNNPEVNQKKEN

Specific function: Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofi

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=486, Percent_Identity=39.0946502057613, Blast_Score=346, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 56096; Mature: 55965

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRASERSQLRGDENFVHAAHHELYNATQRRNLTKATTTIRTKRLNVTAEMPDWEAVRE
CCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEEEEECCCCHHHHHH
AGSGIKRDVGQRLDELLVQFEEAVTARGGHVHWARDAKEAGDIVTKLVEETGEKNVVKIK
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHCCCCCEEEEE
SMATMEIDLNNRLREAGISARETDLAELIVQLGKDKPSHILVPAIHRNRAEIRDIFIREM
CEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECHHCCHHHHHHHHHHCC
PNTDDSLSSEPAELAEASRSFLREQFMKAKVAISGANFGIAETGTVTIMESEGNGRMCLT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEECCCCCEEEE
LPETLISVMGIEKIIPTFQDLEVFLQLLPRSSTGERQAPYVSTWSGVTEGDGPKNFHIVL
CHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEE
VDNGRTAVLSDEIGREALKCIRCSACLNVCPVYERAGGHAYGSTYPGPIGAILSPQMTGI
EECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCHHCC
KNKHDPNAYLPYASSLCGRCNEVCPVKIPFTDILLELRHKKIQTDAPKIEKAMMGAMQLA
CCCCCCCCCCCCHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
WGNSTMWNMITRMVFMGRIMGGSNGKITHLPSFLAGWTDVRDTAVPPKKSFRQWFETEEA
CCCCHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
QQLLADARRDGIHPNNPEVNQKKEN
HHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PPRASERSQLRGDENFVHAAHHELYNATQRRNLTKATTTIRTKRLNVTAEMPDWEAVRE
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEEEEECCCCHHHHHH
AGSGIKRDVGQRLDELLVQFEEAVTARGGHVHWARDAKEAGDIVTKLVEETGEKNVVKIK
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHCCCCCEEEEE
SMATMEIDLNNRLREAGISARETDLAELIVQLGKDKPSHILVPAIHRNRAEIRDIFIREM
CEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECHHCCHHHHHHHHHHCC
PNTDDSLSSEPAELAEASRSFLREQFMKAKVAISGANFGIAETGTVTIMESEGNGRMCLT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEECCCCCEEEE
LPETLISVMGIEKIIPTFQDLEVFLQLLPRSSTGERQAPYVSTWSGVTEGDGPKNFHIVL
CHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEE
VDNGRTAVLSDEIGREALKCIRCSACLNVCPVYERAGGHAYGSTYPGPIGAILSPQMTGI
EECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCHHCC
KNKHDPNAYLPYASSLCGRCNEVCPVKIPFTDILLELRHKKIQTDAPKIEKAMMGAMQLA
CCCCCCCCCCCCHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
WGNSTMWNMITRMVFMGRIMGGSNGKITHLPSFLAGWTDVRDTAVPPKKSFRQWFETEEA
CCCCHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
QQLLADARRDGIHPNNPEVNQKKEN
HHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]