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The map label for this gene is appC [H]

Identifier: 37680920

GI number: 37680920

Start: 2780366

End: 2781391

Strand: Direct

Name: appC [H]

Synonym: VV2736

Alternate gene names: 37680920

Gene position: 2780366-2781391 (Clockwise)

Preceding gene: 37680919

Following gene: 37680921

Centisome position: 82.88

GC content: 49.22

Gene sequence:

>1026_bases
ATGAACAACTTATTTAAGCTGATTCTAGGTAATGCGATTGCTCGCGTTGGTTTGGTCATTGTTTGTCTGTTTATCTTTAT
GGCGGTCGCAGCGCCACTGATCACCAAACATGCTCCAGATAAACGTACTGGTAACCCACACGAATACCCAAGTTTCGTCG
TCAAAGCCGCGCAAGCAGATCCAAATGGTTGGATTGCTACCAACCTTGCCGATGACCGTCGTACTCTTCTTCTGTCGAAG
AAAGCTGATCACGTACTGGGTACTTCTCGTATGGGGCGTGACGTATGGTCACAACTAGCTTACGGTGCACGAGTGTCACT
TGCGGTTGGTTTTGGTGCGGGTATCACCGTGTGTTTCCTCGCAACCGTTATTGGTATCTCAGCGGGTTACTTTGGTGGTC
GTGTTGATGACATTCTCACCGCTGCGATGAACATCATGCTGGTTATTCCTCAGTATCCATTGCTGTTCGTCCTTGCCGCC
TTTATCGGTGAAGCAGGGCCAATGACCATTGCCATTATCATCGGCTGTACCTCCTGGGCCTGGGGTGCGCGGGTTGTCCG
CTCTCAAACCCTTGCACTACGTGAAAAAGAATTTGTTAAAGCCGCAGAAGTATTGGGCGAATCTTCATGGCGCATCATCT
TTGTTGAAATTCTGCCAAACCTGATTCCAATTGTGGGTGCGAGTTTCATCGGCTCGGTAATGTACGCCATCACCATGGAA
TCGATCATTTCCTTCCTTGGTCTAGGCGATCCAAACACCATCAGTTGGGGCATCATGCTGTACAACGTACAGACCTCCTC
TTCAATGCTGATTGGCGCATGGTGGGAACTGCTTGCTCCGTGTATCGCACTGACACTACTCGTCACTGGCCTTGCATTAC
TGAACTTTGCGGTCGATGAGATTGCGAACCCACAACTTCGTTCTCACAAAGGAATGAAGCGCTGGCAGAAGCTAGCGAAA
GAAGACAAGAAAGAGCGTGAGCCTGAAATGGCACCGCAAAATGCACTTTGGAGCGGAGATAAATAA

Upstream 100 bases:

>100_bases
AATTGTTAATCATGACTCTGTTTATGCTGTCATTTAACCTGATTGCCGACATGCTGTATGTCGTACTCGATCCTCGCCTA
CGCAAGGGAGGCAAATAATC

Downstream 100 bases:

>100_bases
TCATGACCGAACCACTTATTTCAATCCGCAACCTTTGCGTTGACTACATCACAGACGCGGGCGATGTCCGCGCTTGTAAC
AACGTTAGCTTTGATATAGC

Product: peptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNNLFKLILGNAIARVGLVIVCLFIFMAVAAPLITKHAPDKRTGNPHEYPSFVVKAAQADPNGWIATNLADDRRTLLLSK
KADHVLGTSRMGRDVWSQLAYGARVSLAVGFGAGITVCFLATVIGISAGYFGGRVDDILTAAMNIMLVIPQYPLLFVLAA
FIGEAGPMTIAIIIGCTSWAWGARVVRSQTLALREKEFVKAAEVLGESSWRIIFVEILPNLIPIVGASFIGSVMYAITME
SIISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCIALTLLVTGLALLNFAVDEIANPQLRSHKGMKRWQKLAK
EDKKEREPEMAPQNALWSGDK

Sequences:

>Translated_341_residues
MNNLFKLILGNAIARVGLVIVCLFIFMAVAAPLITKHAPDKRTGNPHEYPSFVVKAAQADPNGWIATNLADDRRTLLLSK
KADHVLGTSRMGRDVWSQLAYGARVSLAVGFGAGITVCFLATVIGISAGYFGGRVDDILTAAMNIMLVIPQYPLLFVLAA
FIGEAGPMTIAIIIGCTSWAWGARVVRSQTLALREKEFVKAAEVLGESSWRIIFVEILPNLIPIVGASFIGSVMYAITME
SIISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCIALTLLVTGLALLNFAVDEIANPQLRSHKGMKRWQKLAK
EDKKEREPEMAPQNALWSGDK
>Mature_341_residues
MNNLFKLILGNAIARVGLVIVCLFIFMAVAAPLITKHAPDKRTGNPHEYPSFVVKAAQADPNGWIATNLADDRRTLLLSK
KADHVLGTSRMGRDVWSQLAYGARVSLAVGFGAGITVCFLATVIGISAGYFGGRVDDILTAAMNIMLVIPQYPLLFVLAA
FIGEAGPMTIAIIIGCTSWAWGARVVRSQTLALREKEFVKAAEVLGESSWRIIFVEILPNLIPIVGASFIGSVMYAITME
SIISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCIALTLLVTGLALLNFAVDEIANPQLRSHKGMKRWQKLAK
EDKKEREPEMAPQNALWSGDK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=303, Percent_Identity=28.3828382838284, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789889, Length=242, Percent_Identity=33.0578512396694, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787498, Length=302, Percent_Identity=30.1324503311258, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789964, Length=257, Percent_Identity=33.852140077821, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787054, Length=248, Percent_Identity=28.2258064516129, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788505, Length=171, Percent_Identity=30.9941520467836, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37074; Mature: 37074

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLFKLILGNAIARVGLVIVCLFIFMAVAAPLITKHAPDKRTGNPHEYPSFVVKAAQAD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCC
PNGWIATNLADDRRTLLLSKKADHVLGTSRMGRDVWSQLAYGARVSLAVGFGAGITVCFL
CCCCEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHH
ATVIGISAGYFGGRVDDILTAAMNIMLVIPQYPLLFVLAAFIGEAGPMTIAIIIGCTSWA
HHHHHHHCCCCCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHCCCCCEEEEEEEECCCHH
WGARVVRSQTLALREKEFVKAAEVLGESSWRIIFVEILPNLIPIVGASFIGSVMYAITME
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SIISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCIALTLLVTGLALLNFAVDE
HHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IANPQLRSHKGMKRWQKLAKEDKKEREPEMAPQNALWSGDK
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNNLFKLILGNAIARVGLVIVCLFIFMAVAAPLITKHAPDKRTGNPHEYPSFVVKAAQAD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCC
PNGWIATNLADDRRTLLLSKKADHVLGTSRMGRDVWSQLAYGARVSLAVGFGAGITVCFL
CCCCEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHH
ATVIGISAGYFGGRVDDILTAAMNIMLVIPQYPLLFVLAAFIGEAGPMTIAIIIGCTSWA
HHHHHHHCCCCCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHCCCCCEEEEEEEECCCHH
WGARVVRSQTLALREKEFVKAAEVLGESSWRIIFVEILPNLIPIVGASFIGSVMYAITME
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SIISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCIALTLLVTGLALLNFAVDE
HHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IANPQLRSHKGMKRWQKLAKEDKKEREPEMAPQNALWSGDK
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]